3. Definition of vaccine
A vaccine is a biological preparation that
improves immunity to a particular disease. It
contains an agent that resembles disease-causing
microorganism.
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4. Properties of vaccine
Provide long lasting immunity.
It will show both humoral and cellular immunity.
It Should not be induce autoimmunity.
It Should be inexpensive to produce.
Vaccine must also be perceived to be safe.
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5. History Of vaccine
In 1796 british physician Edward Jenner
used the cowpox virus to confer protection
against smallpox.
In 1885 the French microbiologist Louis
Pasteur developed the first vaccine against
rabies.
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6. Types of vaccine found in Bangladesh
Inactivated vaccine
Attenuated vaccine
Toxoid vaccine
Subunit vaccine
Conjugate vaccine
DNA vaccine
Recombinant Vector Vaccines
Vaccine adjuvant
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7. Inactivated vaccine
This vaccines are for those micro-
organisms which are destroyed
with chemicals, heat, radiation, or
antibiotics.
Examples : Cholera vaccine
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14. Vaccine adjuvant
It is added to the vaccine to
increase the body's immune
response to the vaccine.
Example : Sapions
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15. Stages of vaccine production in
Bangladesh
It has several stages for vaccine manufacturing,
Inactivation : This involves making of the antigenic
preparation.
Purification : The isolated antigen is purified
Formulation : The purified antigen is formulated in this step.
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16. Common disease of Bangladesh and their
cause
Hepatitis A: CDC recommends this vaccine because you can get hepatitis A
through contaminated food or water in Bangladesh.
Typhoid :You can get typhoid through contaminated food or water in
Bangladesh
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17. Common disease of Bangladesh and their
causes
Hepatitis B :You can get hepatitis B through sexual contact, contaminated needles, and
blood products
Malaria : When traveling in Bangladesh, you should avoid mosquito bites to prevent
malaria
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18. Common disease of Bangladesh and their
cause
Rabies :Rabies can be found in dogs, bats, and other mammals in
Bangladesh
Yellow Fever: There is no risk of yellow fever in Bangladesh.
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19. Common Viruses & Their Vaccines in
Bangladesh
Disease Name Vaccine Name
Influenza Agrippal S1
Human papilloma virus Cervarix
Cholera Dukora
BCG BCG Vaccine
Rabies Vekorab
Hepatitis B Engerix
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20. Some pharmaceutical which produce
vaccines in Bangladesh
1. Incepta
2. Square
3. Acme
4. Ibne-sina
5. Reneta
6. Beximco
7. Opsonin
8. Globe pharma
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21. Reasons to be vaccinated
Vaccines will help keep you healthy.
Vaccines are as important to your overall health as diet and exercise.
Vaccination can mean the difference between life and death.
Vaccines are safe.
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22. Reasons to be vaccinated
Vaccines won’t give you the disease they are
designed to prevent.
Young and healthy people can get very sick,
too.
Vaccine-preventable diseases are expensive.
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23. Advantages of vaccine in Bangladesh
It has no risk of infection.
Cost effectiveless.
Immune response focused only on antigen of interest.
Show both Humoral & Cell mediated immunity.
Refrigation are not required.
Stable for storage.
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24. Disadvantages Of vaccine in Bangladesh
Many vaccines do not raise immunity
Boosters needed
No local immunity
Higher cost
Shortage of money
Failure in inactivation
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25. Vaccine failure
Primary failure : An individual fails to make an
adequate immune response to initial vaccination
Secondary failure : An individual makes an
adequate immune response initially but then
immunity wanes over time.
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26. Causes of vaccine failure in Bangladesh
Used of expired vaccine
Genetic resistance
Improper storage of vaccine
Mycotoxins
Vaccination reactions.
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27. Recent research
Approaches for designing a preventive HIV vaccine.
Vaccine against Dengue Vaccine.
NIH Scientists Identify New HIV-Inhibiting Protein.
NIH Scientists Find Cause of Rare Immune Disease: Genetic Mutation Leads to Cold
Allergy, Immune Deficiency and Autoimmunity.
NIH Found a Gene That May Play a Role in Type 1 Diabetes.
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