This document provides information on various types of pellet cores that can be used for encapsulation, including their compositions, properties, and applications. It describes sugar pellets, starch pellets, lactose pellets, calcium carbonate pellets, tartaric acid pellets, mannitol pellets, silica pellets, and MCC pellets. For each type, it provides details on grade, particle size ranges, and uses as seed cores for drug layering or coating in formulations requiring controlled or sustained release.

1. ENCAPSULATIONENCAPSULATIONNeutral Pellets and Coating Polymers

2. Sugar Pellets
Grade
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sugar Pellets SS
Sr. No.
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
Mesh Size (ASTM)
120 – 140
100 – 120
80 – 100
70 – 80
60 – 70
50 – 60
45 – 50
45 – 60
40 – 60
40 – 50
40 – 45
35 – 55
35 – 50
35 – 45
35 – 40
30 – 35
25 – 30
20 – 25
18 – 20
16 – 20
16 – 18
14 – 16
12 – 16
12 – 14
10 – 12
Diameter In mm (µm)
0,106 – 0,125
0,125 – 0,150
0,150 – 0,180
0,180 – 0,212
0,212 – 0,250
0,250 – 0,300
0,300 – 0,355
0,250 – 0,355
0,250 – 0,425
0,300 – 0,425
0,355 – 0,425
0,355 – 0,500
0,300 – 0,500
0,400 – 0,450
0,425 – 0,500
0,500 – 0,600
0,600 – 0,710
0,710 – 0,850
0,850 – 1,000
0,850 – 1,180
1,000 – 1,180
1,180 – 1,400
1,400 – 1,700
1,400 – 1,700
1,700 – 2,000
We do customized special cores / pellets for customers on their annual product requirements.
Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are
involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as
to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and,
therefore, entirely your own responsibility.
Sugar Pellets Definitions:
l SPRAYSPHERES™ - SS contains not more than 92 percent of sucrose. Calculated on the dried basis. The dried basis. The remainder consists of
corn starch as per the European Pharmacopoeia.
l Compliance with Ph. Eur., USP/ NF and JP.
l Produced in accordance with the cGMP.
Sugar pellets particle size specifications:
Particle size distribution (analyzed by laser diffraction) shows the symmetrical character of the distribution. The single model profile, associated a
very homogeneous population of SPRAYSPHERES™ - SS.
Sugar PelletsApplication:
Used as cores to be coated in the manufacture of dry pharmaceutical / Nutraceutical / herbal / homeopathy form especially for controlled release &
specially formulations.
SPRAYSPHERES™ - Speciality Products (SS):
Definition:
SPRAYSPHERES™ - SS base of sugar & starch pellets coated with cationic polymers.
Application:
l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.
l Using SPRAYSPHERES™ - SS can be converted to ready to fill pellet technology.
l Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc.
Application
Used as drug - free cores / starter cores for controlled or sustained release,
immediate release, delayed release applications.

3. Starch Pellets
Grade
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Starch Pellets STS
Sr. No.
1
2
3
4
5
6
7
8
9
10
Mesh Size (ASTM)
12 - 14
16 - 18
18 - 20
20 - 30
30 - 40
40 - 50
50 - 60
60 - 80
80 - 100
100 - 200
We do customized special cores / pellets for customers on their annual product requirements.
Starch Pellets Definitions:
l
The dried basis.The remainder consists of sugar.
l Produced in accordance with the cGMP.
Application:
l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs /
unstable drug.
l Using SPRAYSPHERES™ - STS can be converted to ready to fill pellet technology.
l Starter cores for Delayed release / Sustained release / time release / pulse release /
Controlled release & Immediate release applications, etc.
Starch spheres contain more than 92 percent of starch. Calculated on the dried basis.
Used as spherical seed cores for drug layering & film coating.
Also used in manufacture of granules / beadlets with sustained /
controlled release, taste masking & other special properties.
Diameter In mm (µm)
1,400 – 1,700
1,000 – 1,180
0,850 – 1,000
–
–
0,300 – 0,425
0,250 – 0,300
–
0,150 – 0,180
–
Application
Lactose Pellets
We do customized special cores / pellets for customers on their annual product requirements.
Lactose Pellets Definitions:
l
basis.The dried basis.The remainder consists of Starch.
l Produced in accordance with the cGMP.
l Completely for water soluble application a substitute for sugar.
Application:
l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs /
unstable drug.
l Using SPRAYSPHERES™ - LS can be converted to ready to fill pellet technology.
l Starter cores for Delayed release / Sustained release / time release / pulse release /
Controlled release & Immediate release applications, etc.
Lactose spheres contain more than 80 percent of lactose. Calculated on the dried
Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are
involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as
to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and,
therefore, entirely your own responsibility.
Grade
Lactose Pellets LS
Lactose Pellets LS
Lactose Pellets LS
Lactose Pellets LS
Lactose Pellets LS
Lactose Pellets LS
Lactose Pellets LS
Lactose Pellets LS
Sr. No.
1
2
3
4
5
6
7
8
Mesh Size (ASTM)
18 / 20
20 / 30
30 / 40
40 / 50
50 / 60
60 / 80
80 / 100
100 / 200
Used as spherical seed cores for drug layering & film coating.
Also used in manufacture of granules / beadlets with sustained /
controlled release, taste masking & other special properties.
Diameter In mm (µm)
0,850 – 1,000
–
–
0,300 – 0,425
0,250 – 0,300
–
0,150 – 0,180
–
Application

4. Calcium Carbonate Pellets
We do customized special cores / pellets for customers on their annual product requirements.
Grade
Calcium Carbonate Pellets CS -100
Calcium Carbonate Pellets CS-102
Calcium Carbonate Pellets CS-203
Calcium Carbonate Pellets CS-305
Calcium Carbonate Pellets CS-507
Calcium Carbonate Pellets CS-708
Sr. No.
1
2
3
4
5
6
Particle size range (µm)
75 - 212
106 - 212
150 - 300
300 - 500
500 - 710
710 - 850
Used as spherical seed cores for drug layering & film coating.
Also used in manufacture of granules / beads with sustained /
controlled release, taste masking & other special properties.
Diameter In mm (µm)
–
–
–
–
–
–
Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are
involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as
to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and,
therefore, entirely your own responsibility.
SPRAYSPHERES™ - CS
l Calcium Carbonate Neutral Pellets consist of CaCO3 and also used for the controlled release and MUPS formulations in nutraceutical and
pharmaceutical medicine.
l Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most suitable size and
dissolution profile.
Calcium Carbonate Pellets Definitions:
l The SPRAYSPHERES™ - CS have been developed using calcium carbonate (90%) as base and other ingredient is maize starch.
l Calcium carbonate complying with Ph. Eur / USP/ NF.
l Manufacturing in accordance with the cGMP.
Calcium Carbonate General Properties:
l Nearly white hard, uniform and spherical particles. (sphericity degree average >90%)
l Very low friability level.
l Calcium carbonate high physiochemical inertness improves the stability of the finished product.
l Uniform and consistent loading.
l Calcium give a improved taste and mouth feel for the pellets.
l For PH dependent applications
Calcium Carbonate Particle Size Specifications:
l Minimum of 92% (w/w) of SPRAYSPHERES™ - CS are between the lower and the upper limits of the size stated on the label.
l The SPRAYSPHERS™ - CS selection is obtained by the decreasing size by sieving method.
Calcium CarbonateApplication:
l Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug layering and
coating.
l Suitable for non-carcinogenic products.
l Ph controlled applications, these starter cores give a specific ph to the dissolution profile.
l Adopted to controlled release or sustained release formulations SPRAYSPHERES™ - CS make it easy to produce spherical micro granules which
have the most suitable size and dissolution profile to each specific purpose.
Application

5. Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are
involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as
to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and,
therefore, entirely your own responsibility.
Tartaric Acid Pellets
We do customized special cores / pellets for customers on their annual product requirements.
Grade
Tartaric Acid Pellets TS
Tartaric Acid Pellets TS
Tartaric Acid Pellets LS
Tartaric Acid Pellets TS
Tartaric Acid Pellets TS
Tartaric Acid Pellets TS
Tartaric Acid Pellets TS
Sr. No.
1
2
3
4
5
6
Particle size range (µm)
20 / 30
30 / 40
40 / 50
50 / 60
60 / 80
80 / 100
100 / 200
Used as spherical seed cores for drug layering & film coating.
Also used in manufacture of granules / beads with sustained /
controlled release, taste masking & other special properties.
Diameter In mm (µm)
–
–
–
–
–
–
–
SPRAYSPHERES™ - TS
l Tartaric acid pellets and also used for the controlled release and MUPS formulations in nutraceutical and pharmaceutical medicine.
l Adapted for controlled release or sustained release formulations to produce spherical granules or pellets which have the most suitable size and
dissolution profile.
l Tartaric acid complying with Ph. Eur / USP/ NF.
l Manufacturing in accordance with the cGMP.
Tartaric acid General Properties:
l Very low friability level.
l Tartaric acid high physiochemical inertness improves the stability of the finished product.
l Uniform and consistent loading.
l For PH dependent applications
Tartaric acid pelletApplication:
l Used as cores to be coated in the manufacture of dry pharmaceutical forms. It enables greater accuracy and consistency in drug layering and
coating.
l Suitable for non-carcinogenic products.
l Ph controlled applications; these starter cores give a specific ph to the dissolution profile.
Mannitol Pellets
We do customized special cores / pellets for customers on their annual product requirements.
Grade
Mannitol Pellets MAS
Mannitol Pellets MAS
Mannitol Pellets MAS
Mannitol Pellets MAS
Mannitol Pellets MAS
Mannitol Pellets MAS
Mannitol Pellets MAS
Mannitol Pellets MAS
Sr. No.
1
2
3
4
5
6
7
8
Mesh Size (ASTM)
18 / 20
20 / 30
30 / 40
40 / 50
50 / 60
60 / 80
80 / 100
100 / 200
Used as spherical seed cores for drug layering & film coating.
Also used in manufacture of granules / beadlets with sustained /
controlled release, taste masking & other special properties.
Diameter In mm (µm)
0,850 – 1,000
–
–
0,300 – 0,425
0,250 – 0,300
–
0,150 – 0,180
–
Application
Application
SPRAYSPHERES™ - MAS
Manitol Pellets Definitions:
l
l Produced in accordance with the cGMP.
l Completely for water soluble application a substitute for sugar.
Application:
l Suitable for very low / high dosage forms and for drugs with a low therapeutic margin.
l Used as cores to be coated in the manufacture of highly hygroscopic / soluble drugs / unstable drug.
l Using SPRAYSPHERES™ - MAS can be converted to ready to fill pellet technology.
l Starter cores for Delayed release / Sustained release / time release / pulse release / Controlled release & Immediate release applications, etc.
Manitol spheres contain more than 80 percent of Manitol. Calculated on the dried basis.The dried basis.The remainder consists of Starch.

6. Silica Pellets
SPRAYSPHERES™ -AS
Silica Pellets Neutral pellets Consist of SiO2 and mainly used as a core for drug loading of insoluble and instable drug. Also used in MUPS
technology.
Silica Pellets Definitions:
l The SPRAYSPHERES™ -AS have been developed using Silicon dioxide (< 75%) as base.
l Silica complying with Ph. Eur / USP/ NF.
l Manufacturing in accordance with the cGMP.
Silica Pellets General properties:
l Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)
l Very low friability level.
MCC Pellets
SPRAYSPHERES™ - MS
Microcrystalline Cellulose Pellets Neutral pellets for sugar free products, highly soluble & controlled released formulation products.
MCC Pellets Definitions:
l The SPRAYSPHERES™ - MS have been developed using microcrystalline cellulose (MCC) as base.
l Microcrystalline cellulose is purifies, partly devolymerised cellulose, prepared from alpha cellulose.
l MCC complying with Ph. Eur.
l Manufacturing in accordance with the cGMP.
MCC Pellets General properties:
l Nearly white hard, uniform and spherical particles. (Sphericity degree average >90%)
l Very low friability level.
l MCC high physiochemical inertness improves the stability of the finished product.
l Insoluble in water, absolute ethanol, acetone.
We do customized special cores / pellets for customers on their annual product requirements.
Grade
Silica Pellets AS-100
Silica Pellets AS-102
Silica Pellets AS-203
Silica Pellets AS-305
Silica Pellets AS-507
Silica Pellets AS-708
Sr. No.
1
2
3
4
5
6
Particle size range (µm)
75 - 212
106 - 212
150 - 300
300 - 500
500 - 710
710 - 850
Used as spherical seed cores for drug layering & film coating.
Also used in manufacture of granules / beads with sustained /
controlled release, taste masking & other special properties.
Diameter In mm (µm)
–
–
–
–
–
–
Application
We do customized special cores / pellets for customers on their annual product requirements.
Grade
MCC Pellets MS-100
MCC Pellets MS-102
MCC Pellets MS-203
MCC Pellets MS-305
MCC Pellets MS-507
MCC Pellets MS-708
Sr. No.
1
2
3
4
5
6
Particle size range (µm)
75 - 212
106 - 212
150 - 300
300 - 500
500 - 710
710 - 850
Used as spherical seed cores for drug layering & film coating.
Also used in manufacture of granules / beads with sustained /
controlled release, taste masking & other special properties.
Diameter In mm (µm)
–
–
–
–
–
–
Application
Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are
involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as
to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and,
therefore, entirely your own responsibility.

7. Disclaimer : This information and our technical advice - whether verbal, in writing or by way of trials - are given in good faith but without warranty, and this also applies where proprietary rights of third parties are
involved. Our advice does not release you from the obligation to verify the information currently provided - especially that contained in our safety data and technical information sheets - and to test our products as
to their suitability for the intended processes and uses. The application, use and processing our products and the products manufactured by you on the basis of our technical advice are beyond our control and,
therefore, entirely your own responsibility.
We do customized Projects / Development for customer based on their annual requirement of the product. Pellets from 50 - 2500 micron sizes possible.
Neutral Excipients
Spraypol L-30D-55
Spraypol E-100
Spraypol EPO
Spraypol L-100
Spraypol S-100
Sr. No.
1
2
3
4
5
Percentage (%)
30.00%
100%
100%
100%
100%
Therapeutical
Polymer for enteric coating
Polymer for enteric coating
Polymer for enteric coating
Polymer for enteric coating
Polymer for enteric coating
PH Release
PH 7.5 - 5
PH 1 - 1.5
PH 1 - 1.5
PH 6 - 7
PH up to 7.5
Acrylic Coating Polymer
Application: Drug delivery in Jejunum.
Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.
L - 30 D - 55
Application: Taste and odour masking, insolating coating, transdermal applications, moisture protection.
Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.
E - 100
Application: Taste and odour masking, Insolating coating, transdermal applications, moisture protection.
Functionality: Cationic polymer with dimethylaminoethyl ammonium functional groups.
EPO
Application: Drug delivery in Jejunum.
Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.
L - 100
Application: Drug delivery in Jejunum.
Functionality: Anionic polymer of methacrylic acid and ethacrylates with -COOH functional groups.
S - 100
DUODENUM PH > 5.5
SPRAYPOL L 30 D-55
JEJUNM PH 6-7
TIME CONTROLLED
SUSTAINED RELEASE
SPRAYPOL L 100
COLON ASCENDENS PH 6-7
SPRAYPOL S 100
IIEUM PH UP TO 7.5
SPRAYPOL S 100
STOMACH PH 1- 1.5
SPRAYPOL E 100
SPRAYPOL EPO

8. Survey No. 146, H. No.1 (PT),
Vasai Phata Highway Junction, Pelhar,
Nh8, Vasai (E) - 401 208, Maharashtra (India).
Tel. : (+91-22) 30018900 / 30018915 - 98
Mob. : (+91) 986 723 6594
Fax : (+91-22) 30018908 / 30018913
E-mail : umang@umangpharmatech.com
Today the company has three major
divisions: Personal care, Bakery and food
ingredients, Pharmaceutical division for
innovative dosage form development.
Websites:
www.umangpharmatech.com
www.umangengineering.com
www.extruderspheronizer.com
Umang Pharmatech Pvt. Ltd. A truly global organization...
Today the company has three major
divisions: Personal care, Bakery and food
ingredients, Pharmaceutical division for
innovative dosage form development.
Websites:
www.concept-machines.com
www.coating-machines.com
Today the company has three major
divisions: Personal care, Bakery and food
ingredients, Pharmaceutical division for
innovative dosage form development.
Websites:
www.umangpharma.com
www.cosmeticbeads.com
Today the company has three major
divisions: Personal care, Bakery and food
ingredients, Pharmaceutical division for
innovative dosage form development.
Websites:
www.umangpharma.com
www.edibleglitters.com
www.ediblefilm.co.uk
Today the company has three major
divisions: Personal care, Bakery and food
ingredients, Pharmaceutical division for
innovative dosage form development.
Websites:
www.umangpharmaceuticals.com
www.pharmaceuticalpellets.com
www.pharma-spheres.com
Today the company has three major
divisions: Personal care, Bakery and food
ingredients, Pharmaceutical division for
innovative dosage form development.
Websites:
www.umangpharmaceuticals.com
www.micro-pellets.com
www.pharma-spheres.com
Umang was incepted in the year 1982, with an objective to serve the clients with all kinds of equipments and accessories under one roof.
Within a very short span of time, we succeeded to be the most reliable brand name in the market supplying equipments and solutions to the
Pharmaceutical industry for Pelletization and granulation solutions.
In 2007, the company ventured into solutions for Personal care industry majorly focusing on Oral care products, giving encapsulated
ingredients for cooling applications. In 2009, the company further integrated itself to give solutions for Bakery and food applications like
Chewing gum, mouth dissolving films etc. Today the company has three major divisions: Personal care, Bakery and food ingredients,
Pharmaceutical division for innovative dosage form development like geletain beads, Edible films, innovative encapsulation applications.
© 2012. All rights reserved.
Pelletization and Edible Film Solutions Concept Range
Personal Care and Detergents Bakery and Food Decoration
Pharmaceutical and Nutraceutical Neutral Pellets and Coating Polymers