How can Caleva help me to make extrudate or pellets from my pharmaceutical, catalyst, ceramic, cosmetic, petrochemical materials?

1. Celebrating 50 Years as market leader in manufacturing and developing
equipment for the production of pellets or extrudate (beads or spheroids) by Extrusion
and Spheronization™ from Caleva®.
THE SPHERONIZATION COMPANY

2. ABOUT USA market leader in manufacturing and developing equipment
for the production of pellets (beads or spheroids) by Extrusion
and Spheronization™
HISTORY
For over 50 years Caleva Process Solutions have designed and
manufactured high quality products that have shaped the way
our clients understand extrusion and spheronization.
We work in close partnership with our customers from various
backgrounds in their developments that surround the need to
make pellets and extrudates using the processes of extrusion
and spheronization.
If you are involved in the pharmaceutical, catalyst or ceramic
industries (beads) and are thinking about extrusion and
spheronization to make pellets then talk to Caleva.

3. DISTRIBUTORS
WHERE WE OPERATE
EUROPE
THE AMERICAS
ASIA
MIDDLE EAST AND AFRICA

4. A single bench top unit offering you advantages for university
teaching that is cost effective to purchase, easy and safe to
use and is robust in the hands of student users.
Offers best use of your benchtop space. You will have a safer
and more efficient work environment. “Tool-Less Technology”
reduces cleaning time and increases interaction of your students.
Suitable for a wide range of material, from easily mixed pharmaceutical
formulations to less easy to mix catalyst and inorganic mixes for the
petrochemical industry.
Use batches from 10g up to 100g whilst
saving your bench space and offering you a
high level of flexibility for your student groups
CALEVA MULTI LAB

5. You can achieve excellent uniformity within and between
batches whilst reducing your product cost and overcome
limited product availability.
Ease of use together with the possibility to coat very small
batches makes the MCD-2 particularly attractive both for
university teaching and research laboratories.
From a single tablet up to about 150 tablets
From a few grams to about 60 grams of small pellets
From a single capsule to a "small handful"
TABLET AND PELLET
MINI COATER DRIER

6. The Caleva Mixer Torque Rheometer is well established as a
valuable formulation development, formulation research and
production quality control tool.
It will uniquely provide you with quantitative and reproducible
measurement of the rheology of a wet mass.
Having this information will enable you to optimize your
formulations in the least possible time. It will enable you
to investigate product and excipient quality issues in a
quantitative and meaningful way.
The data can be used as part of scale-up and the instrument
can also be used for quality control in production. The MTR-3
is designed to enable the user to quantify the consistency
properties of a wet mass.
MIXER TORQUE
RHEOMETER

7. EXTRUDER AND SPHERONIZER WITH
BATCH SIZE FLEXIBILITY
FROM 50 GRAMS TO 1.5 KG
If you plan to work with batch sizes from between 50 g and
1500 g then this Caleva kit will give you the flexibility you need.
The Multi-Bowl Spheronization Kit is designed for your
laboratory bench-top and includes the following 2 pieces
The Caleva bench-top screen Extruder 20 and Caleva
Multi Bowl Spheronizer base with a 250mm, 120 mm,
85mm or 60mm diameter bowl.
MULTI BOWL
SPHERONIZER

8. EXTRUDER AND SPHERONIZER WITH BATCH SIZE
FLEXIBILITY FROM 50 GRAMS TO 1.5 KG
The Caleva variable Density Kit will allow you to develop pellets
with different densities, thus widening your chance of
achieving a successful formulation. The kit is made up of the
Caleva Variable Density Extruder and the Multi Bowl Benchtop
Spheronizerw ith a 250 mm diameter bowl attached.
The Caleva Bench-top VariableD ensity Extruder and Caleva
Multi Bowl Spheronizer base with a 250mm, 120 mm,
85mm or 60mm diameterb owl.
VARIABLE DENSITY KIT

9. EXTRUDER AND SPHERONIZER WITH
BATCH SIZE FLEXIBILITY
FROM 2 TO 8 KGs
The Caleva Gear Extruder high density Extrusion and Spheronization
kit is a small scale production kit with an output between about 40
to 60 kg per hour linked with a Caleva Spheronizer 500.
The Caleva gear extruder 40 and Caleva
Spheronizer 500 base with 500mm diameter bowl.
HIGH DENSITY KIT

10. EXTRUDER AND SPHERONIZERW ITH
BATCH SIZE FLEXIBILITY
FROM 250 GRAMS TO 4 KG
The 50 kg/h system for your product development, and for
your contract manufacture. You can clean it quickly and
change your products regularly. This rapid cleaning allows
you to work with different products in the same equipment
leading a more efficient use of your time and resources.
The Caleva screen Extruder 35 and Caleva
Spheronizer 380 base with a 380mm diameter bowl.
50 KG PER HOUR
SPHERONIZER KIT

11. EXTRUDER AND SPHERONIZER
WITH BATCH SIZE FLEXIBILITY
FROM 1 TO 8 KG
With the Caleva 100 kg/hour System you can easily dismantle
and clean this equipment to allow you to work with different
products using this “easy to clean” system. Do you want to
spend more time producing and less time cleaning!
The Caleva screen Extruder 35 and Caleva
Spheronizer 500 base with a 500mm diameter bowl.
100KG PER HOUR
SPHERONIZER KIT

12. EXTRUDER AND SPHERONIZER
WITH BATCH SIZE FLEXIBILITY
FROM 2 TO 15K G
Product trials show that this very compact yet efficient
extruder can produce in excess of 250 kg of extrudate
per hour using axial extrusion.
Other die patterns and shapes suitable for “industrial”
materials in the catalyst and petrochemical industries
are available and are proving to be extremely successful..
The Caleva twin screw Extruder TSE70 and Caleva
Spheronizer 700 base with a 700mm diameter bowl.
150KG PER HOUR
SPHERONIZER KIT

13. VARIABLE DENSITY TWIN
SCREW EXTRUDER
PRODUCTION EXTRUDER WITH
THROUGHPUT CAPACITY
OF UP TO 250 KG PER HOUR
Product trials show that this very compact yet efficient
extruder can produce in excess of 250 kg of extrudate
per hour using axial extrusion.
Other die patterns and shapes suitable for “industrial”
materials in the catalyst and petrochemical industries
are available and are proving to be extremely successful..
VARIABLE DENSITY TWIN
SCREW EXTRUDER
PRODUCTION EXTRUDER WITH
THROUGHPUT CAPACITY
OF UP TO 250 KG PER HOUR
Product trials show that this very compact yet efficient
extruder can produce in excess of 250 kg of extrudate
per hour using axial extrusion.
Other die patterns and shapes suitable for “industrial”
materials in the catalyst and petrochemical industries
are available and are proving to be extremely successful..

14. APPLICATION NOTES &
INTERESTING BLOG
ARTICLES
SAVE TIME AND COST IN YOUR PRODUCT DEVELOPMENT with the Mixer Torque Rheometer
A PRACTICAL EXAMPLE OF OF “END POINT” DETERMINATION USING THE CALEVA MIXER TORQUE RHEOMETER
RESULTS OF A MIXING TRIAL USING THE CALEVA MULTI LAB MIXER/GRANULATOR WITH SOME DIFFICULT MATERIALS
Caleva Mixer Torque Rheometer - The importance of mixing time for your formulation development and production
What type of extruder do I need?
It is possible to purchase extruders and spheronizers at a lower price .... but will it cost you more in the longer term?
Mini Coater Drier results - can they be used in the scale up of process development?
Coating of very small capsules with the Caleva Mini Coater Drier
What characteristics should my extrudate have?
Are you working with thick, viscous or sticky granulations?
How do I mix very small batches of my product?
Can you help with my cosmetics formulation?
Catalyst Pellets cracked! The strange apple sauce method