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Principles of
medical
genetic
Thalía Ramírez Montoya
DNA help us to understand and
found different diagnose
dissease .
Genetic is the study
of genes, heredity, and genetic
variation in living organisms.
DNA is the prerequisite for
life’s inception. It transfers
hereditary information and it
controls the production of
proteins.
New cancer marker identified;
possible therapeutic target
for breast cancer.
Boston University
July 31 2015.
New cancer marker identified;
possible therapeutic target for
breast cancer.
A gene called IL13RA2 its
involved to breast cancer.
The study consist in markers of the
surface of the cancer cells to gene
expression profile of breast tumor.
Where they found that this
molecule was abundant in
metastatic or later stage of BLBC.
The amount of IL13RA2
expression in the cancer cells the
tumor growth was significantly
slower in models , which
suggested that IL13RA2 was
involved in cancer growth and
spread.
Student
observation
I think this research is
important because this gen
could be a target to many
genic therapy that can
prevent breast cancer and
other cancers related to the
gen.
Urine test for early
stage pancreatic
cancer possible after
biomarker discovery.
Barts Cancer Institute,
Queen Mary University
of London.
August 3 2015.
Urine test for early stage
pancreatic cancer possible after
biomarker discovery.
A team at Barts Cancer Institute,
has shown that the three-protein
'signature' can both identify the
most common form of pancreatic
cancer when still in its early
stages .
The investigation consisted in 117
samples from patients , around
1500 proteins were found in the
urine .
Three proteins LYVE1, REG1A and
TFF1 were selected for closer
examination because Patients with
pancreatic cancer were found to have
increased levels of each of the three
proteins.
Student observation:
It is really great that with a
simple test we can discovered
a cancer because that can be
used for an early and cheaper
diagnosis , and prevent a
bigger stage of the cancer.
MEDICA
L
UTILITY
MEDICAL UTILITY
These research are really important
to the advanced of medicine, it
brings a new perspective of how we
can treat cancer and maybe also
find a way to suppress the genes
that develop it.
The first one could help
investigators to create cancer
therapies that reduces the levels
of IL13RA2 in the body and giving
a hope to breast cancer patients.
The second discovery could lead to a non-invasive, inexpensive test to
screen people at high risk of developing pancreatic cancer.
BIBLIOGRAPHY
•  Boston University Medical Center. "New cancer marker identified;
possible therapeutic target for breast cancer." ScienceDaily.
ScienceDaily, 31 July 2015.
<www.sciencedaily.com/releases/2015/07/150731105250.htm
• Pancreatic Cancer Research Fund. "Urine test for early stage
pancreatic cancer possible after biomarker discovery." ScienceDaily.
ScienceDaily, 3 August 2015.
<www.sciencedaily.com/releases/2015/08/150803083345.htm>.
Principles of medical genetic

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Principles of medical genetic

  • 2.
  • 3.
  • 4. DNA help us to understand and found different diagnose dissease . Genetic is the study of genes, heredity, and genetic variation in living organisms. DNA is the prerequisite for life’s inception. It transfers hereditary information and it controls the production of proteins.
  • 5. New cancer marker identified; possible therapeutic target for breast cancer. Boston University July 31 2015.
  • 6. New cancer marker identified; possible therapeutic target for breast cancer. A gene called IL13RA2 its involved to breast cancer.
  • 7. The study consist in markers of the surface of the cancer cells to gene expression profile of breast tumor. Where they found that this molecule was abundant in metastatic or later stage of BLBC.
  • 8. The amount of IL13RA2 expression in the cancer cells the tumor growth was significantly slower in models , which suggested that IL13RA2 was involved in cancer growth and spread.
  • 9. Student observation I think this research is important because this gen could be a target to many genic therapy that can prevent breast cancer and other cancers related to the gen.
  • 10. Urine test for early stage pancreatic cancer possible after biomarker discovery. Barts Cancer Institute, Queen Mary University of London. August 3 2015.
  • 11. Urine test for early stage pancreatic cancer possible after biomarker discovery. A team at Barts Cancer Institute, has shown that the three-protein 'signature' can both identify the most common form of pancreatic cancer when still in its early stages .
  • 12. The investigation consisted in 117 samples from patients , around 1500 proteins were found in the urine .
  • 13. Three proteins LYVE1, REG1A and TFF1 were selected for closer examination because Patients with pancreatic cancer were found to have increased levels of each of the three proteins.
  • 14. Student observation: It is really great that with a simple test we can discovered a cancer because that can be used for an early and cheaper diagnosis , and prevent a bigger stage of the cancer.
  • 16. MEDICAL UTILITY These research are really important to the advanced of medicine, it brings a new perspective of how we can treat cancer and maybe also find a way to suppress the genes that develop it.
  • 17. The first one could help investigators to create cancer therapies that reduces the levels of IL13RA2 in the body and giving a hope to breast cancer patients.
  • 18. The second discovery could lead to a non-invasive, inexpensive test to screen people at high risk of developing pancreatic cancer.
  • 19. BIBLIOGRAPHY •  Boston University Medical Center. "New cancer marker identified; possible therapeutic target for breast cancer." ScienceDaily. ScienceDaily, 31 July 2015. <www.sciencedaily.com/releases/2015/07/150731105250.htm • Pancreatic Cancer Research Fund. "Urine test for early stage pancreatic cancer possible after biomarker discovery." ScienceDaily. ScienceDaily, 3 August 2015. <www.sciencedaily.com/releases/2015/08/150803083345.htm>.