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1. MCQs Revision Biochemistry for
NEET
Part –II
Jan - 2018
DR. SMILY PRUTHI PAHWA
(MD-BIOCHEMISTRY)
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2. Q1. Defect in alpha oxidation of fatty acid leads
to :
a) Refsum’s disease
b) Jamaican Vomiting Sickness
c) Zellweger syndrome
d) Dicarboxylic aciduria
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3. Q1. Defect in alpha oxidation of fatty acid leads
to :
a) Refsum’s disease
b) Jamaican Vomiting Sickness
c) Zellweger syndrome
d) Dicarboxylic aciduria
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4. Defect in Peroxisomes
Defect in alpha oxidation Defect in oxidation of VLCFA
Refsum’s disease Zellweger syndrome
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5. Jamaican Vomiting Sickness
• Unripe fruit of akee tree
• Hypoglycin
• Inhibits Fatty Acyl CoA Dehydrogenase
• Severe hypoglycemia after ingestion
• Sudden vomiting 2-6 hours after ingestion
• Convulsions, coma & death
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6. Alpha – oxidation
• Peroxisomes & ER
• For branched chain FA
• Removal of 1 carbon from alpha carbon atom
• No ATPs produced
Refsum’s disease –
• Defect in alpha oxidation in peroxisomes
• Phytanic acid not oxidized
• Restrict dairy products & green leafy vegetables
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7. Q2. A tRNA molecule that is supposed to carry
cysteine (tRNAcys) is mischarged. so that it actually
carries alanine (ala-tRNAcys). Assuming no
correction occurs, what will be the fate of this
alanine residue during protein synthesis?
A. It will be incorporated into a protein in
response to an alanine codon.
B. It will be incorporated into a protein in
response to a cysteine codon.
C. It will remain attached to the tRNA as it cannot
be used for protein synthesis.
D. It will be chemically converted to cysteine by
cellular-enzymes.
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8. Q2. A tRNA molecule that is supposed to carry
cysteine (tRNAcys) is mischarged. so that it actually
carries alanine (ala-tRNAcys). Assuming no
correction occurs, what will be the fate of this
alanine residue during protein synthesis?
A. It will be incorporated into a protein in
response to an alanine codon.
B. It will be incorporated into a protein in
response to a cysteine codon.
C. It will remain attached to the tRNA as it cannot
be used for protein synthesis.
D. It will be chemically converted to cysteine by
cellular-enzymes.
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9. Q3. The hydrolytic step leading to the release
of a polypeptide chain from a ribosome is
catalyzed by which of the following?
a. Dissociation of ribosomes
b. Peptidyl transferase
c. Release factors
d. Stop codons
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10. Q3. The hydrolytic step leading to the release
of a polypeptide chain from a ribosome is
catalyzed by which of the following?
a. Dissociation of ribosomes
b. Peptidyl transferase
c. Release factors
d. Stop codons
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11. Q4. What is the importance of lactic acid
production in glycolysis?
A. Regeneration of NAD
B. Regeneration of NADH
C. Synthesis of ATP
D. Exergonic reaction
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13. Q4. What is the importance of lactic acid
production in glycolysis?
A. Regeneration of NAD
B. Regeneration of NADH
C. Synthesis of ATP
D. Exergonic reaction
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14. Q5. The given is the structure of protein. Which
bond is responsible for this structure?
a) Disulfide bond
b) Hydrophobic bond
c) Hydrogen bond
d) Covalent bond
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15. Q5. The given is the structure of protein. Which
bond is responsible for this structure?
a) Disulfide bond
b) Hydrophobic bond
c) Hydrogen bond
d) Covalent bond
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16. Q6. Which of the following is true about ketone
bodies
a. Acetoacetate is most common ketone body
present in blood
b. Beta hydroxybutyrate is the first ketone body
to be synthesized
c. Thiophorase is absent in liver
d. Muscle can not utilize ketone bodies
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17. Q6. Which of the following is true about ketone
bodies
a. Acetoacetate is most common ketone body
present in blood
b. Beta hydroxybutyrate is the first ketone body
to be synthesized
c. Thiophorase is absent in liver
d. Muscle can not utilize ketone bodies
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18. Q7. Which one of the following tissues can
metabolize glucose, fatty acids, and ketone
bodies for ATP production?
a. Liver
b. Muscle
c. Brain
d. Red blood cells
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19. Q7. Which one of the following tissues can
metabolize glucose, fatty acids, and ketone
bodies for ATP production?
a. Liver
b. Muscle
c. Brain
d. Red blood cells
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20. Q8. All of the following Lipoproteins are
increased in type 3 Hyperlipoproteinemia,
EXCEPT :
a. VLDL Remnant
b. Chylomicron remnant
c. Triglycerides
d. IDL (Intermediate density lipoprotein)
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21. Q8. All of the following Lipoproteins are
increased in type 3 Hyperlipoproteinemia,
EXCEPT :
a. VLDL Remnant
b. Chylomicron remnant
c. Triglycerides
d. IDL (Intermediate density lipoprotein)
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22. Q9. HDL is synthesized and secreted from :
a. Liver
b. Peripheral tissue
c. Adipose tissue
d. Muscle
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23. Q9. HDL is synthesized and secreted from :
a. Liver
b. Peripheral tissue
c. Adipose tissue
d. Muscle
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24. Q10. The base sequence of the strand of DNA
used as the template for transcription has the
base sequence GATCTAC. What is the base
sequence of RNA product?
a. CTAGATG b. GTAGATC
c. GAUCUAC d. GUAGAUC
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25. Q10. The base sequence of the strand of DNA
used as the template for transcription has the
base sequence GATCTAC. What is the base
sequence of RNA product?
a. CTAGATG b. GTAGATC
c. GAUCUAC d. GUAGAUC
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