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ASSIGNMENT ON : IMPORTANCE OF ANTIBIOTICS AND ANTISEPTICS , ITS
TYPES AND APPLICATION IN THE FIELD OF MICROBIOLOGY
History of antibody and antiseptics:
• Antibodes :
• Antiseptics ;
Key Points :










Antibiotics :



Classification of antibiotics

•
•
•
On the basis of mechanism of action:
• Cell Wall Synthesis inhibitors:
Protein Synthesis Inhibitors
 Inhibit 30s Subunit
 Inhibit 50s Subunit
• DNA Synthesis Inhibitors
RNA synthesis Inhibitors
Mycolic Acid synthesisinhibitors
Folic Acid synthesis inhibitors
On the basis of mechanism of action:
2. Use of antimicrobials in aquaculture :
On the basis of spectrum activity :
• Broad spectrum antibiotic : A broad-spectrum antibiotic antibiotic
antibiotic
 Ampicillin.
 Tetracycline
 Chlorampenicol
 Erythromycin
• Short spectrum antibiotics: Short -spectrum
microbiota
……..examples are -
Penicillin – G
 Cloxacillin
On the basis of mode of action :
Bacteriostatic antibiotics : Bacteriostatic antibiotics
Ex :
• Bacteriocidal antibiotics : Bactericidal antibiotics bacteriostatic antibiotics
Bactericidal antibiotics
Antibiotics indications :
 Meningitis
Osteomyelitis
 Urinogenital Infections
 Gall Infections
Sepsis
Quinsy
 Skin Infections
Pneumonia
 Mucous MembraneInfections
 Scarlet Fever
Scarlet Fever
 Diphtheria
Siberian Ulcer
Gynecologic Infections
Syphilis
Respiratory Infections
 ENT Infections
 Fungous Infections
Misuse of antibiotics :
Antibiotics resistance :
OR
The ability of a microorganism to produce aprotein that disables an antibiotic or
preventstransport of the antibiotic into the cell.
Cross-resistance :
• Cross-resistance to a particularantibiotic that often results
inresistance to other antibiotics,usually from a similar
chemical class,to which the bacteria may not havebeen
exposed
• Cross-resistance can occur, forexample, to both colistin
and polymyxinB or to both clindamycin and lincomycin
Mistreatment of Doctor :
• Inappropriate prescription :
40 % antimicrobials prescribed inappropriate
. Some 150million prescriptions are written
annually in t theUSA And Of those, 50 million are
absolutelyunnecessary or inappropriate
 You get a fever. You have diarrhoea.You catch a cold. Take a couple
ofantibiotics (Amoxicillin ,Azithromycin)
 You should avoid it ,don’t takeantibiotics without prescription.
Antibiotics side effects :
• The most common side effects ofantibiotics :
Unconsciousness of Patient :
Without proper directionthe patient take the drug
They do not maintain thedosage intervals andcomplete the
dose
Patient stop the drug whenfeel better.
What Is The Role Of Pharmacist :
The pharmacist should review the previous diseaseshistory of the patient
Hypersensitivity reaction of Drug
 Drug-drug interaction
Exact dose and frequency of the drug
When the drug should be taken before or after meal
Suggest not to stop the antibiotics without completethe course even feel better
My Opinion -
• The doctor must be concern about the diseasewhether it viral or
bacterial.
• They should not prescribed the drug without test orover sure .
• The pharmacist should also more conscious aboutthe dose ,drug
interaction, resistant andhypersensitivity of the drug .
• The patient should strictly maintain the suggestionof the pharmacist
ANTISEPTICS :
• ANTISEPTICS
Use in surgery :
COMMON ANTISEPTICS :
• ALCOHOLS: (surgical alcohol
• Ethanol (60-90%) :
• 1-Propanol (60-70%) :
• 2- Propanol/isopropanol (70-80%)
QUATERNARY AMMONIUM
COMPOUNDS: (Quats or QAC’s)
3 BORIC ACID
 CHLORHEXIDINE GLUCONATE
CLASSIFICATIONS OF ANTISEPTICS :
Characteristics of an ideal antiseptics :
USES :
SIDE EFFECTS OF ANTISEPTICS :
Other Antiseptics in Ayurveda :
Thank
You

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Importance of Antibiotics and Antiseptics: History, Types, Uses

  • 1. ASSIGNMENT ON : IMPORTANCE OF ANTIBIOTICS AND ANTISEPTICS , ITS TYPES AND APPLICATION IN THE FIELD OF MICROBIOLOGY
  • 2. History of antibody and antiseptics: • Antibodes : • Antiseptics ;
  • 6. On the basis of mechanism of action: • Cell Wall Synthesis inhibitors: Protein Synthesis Inhibitors  Inhibit 30s Subunit  Inhibit 50s Subunit • DNA Synthesis Inhibitors RNA synthesis Inhibitors Mycolic Acid synthesisinhibitors Folic Acid synthesis inhibitors
  • 7. On the basis of mechanism of action:
  • 8. 2. Use of antimicrobials in aquaculture :
  • 9. On the basis of spectrum activity : • Broad spectrum antibiotic : A broad-spectrum antibiotic antibiotic antibiotic  Ampicillin.  Tetracycline  Chlorampenicol  Erythromycin • Short spectrum antibiotics: Short -spectrum microbiota ……..examples are - Penicillin – G  Cloxacillin
  • 10. On the basis of mode of action : Bacteriostatic antibiotics : Bacteriostatic antibiotics Ex : • Bacteriocidal antibiotics : Bactericidal antibiotics bacteriostatic antibiotics Bactericidal antibiotics
  • 11. Antibiotics indications :  Meningitis Osteomyelitis  Urinogenital Infections  Gall Infections Sepsis Quinsy  Skin Infections Pneumonia  Mucous MembraneInfections  Scarlet Fever Scarlet Fever  Diphtheria Siberian Ulcer Gynecologic Infections Syphilis Respiratory Infections  ENT Infections  Fungous Infections
  • 13. Antibiotics resistance : OR The ability of a microorganism to produce aprotein that disables an antibiotic or preventstransport of the antibiotic into the cell.
  • 14. Cross-resistance : • Cross-resistance to a particularantibiotic that often results inresistance to other antibiotics,usually from a similar chemical class,to which the bacteria may not havebeen exposed • Cross-resistance can occur, forexample, to both colistin and polymyxinB or to both clindamycin and lincomycin
  • 15. Mistreatment of Doctor : • Inappropriate prescription : 40 % antimicrobials prescribed inappropriate . Some 150million prescriptions are written annually in t theUSA And Of those, 50 million are absolutelyunnecessary or inappropriate
  • 16.  You get a fever. You have diarrhoea.You catch a cold. Take a couple ofantibiotics (Amoxicillin ,Azithromycin)  You should avoid it ,don’t takeantibiotics without prescription.
  • 17. Antibiotics side effects : • The most common side effects ofantibiotics :
  • 18. Unconsciousness of Patient : Without proper directionthe patient take the drug They do not maintain thedosage intervals andcomplete the dose Patient stop the drug whenfeel better.
  • 19. What Is The Role Of Pharmacist : The pharmacist should review the previous diseaseshistory of the patient Hypersensitivity reaction of Drug  Drug-drug interaction Exact dose and frequency of the drug When the drug should be taken before or after meal Suggest not to stop the antibiotics without completethe course even feel better
  • 20. My Opinion - • The doctor must be concern about the diseasewhether it viral or bacterial. • They should not prescribed the drug without test orover sure . • The pharmacist should also more conscious aboutthe dose ,drug interaction, resistant andhypersensitivity of the drug . • The patient should strictly maintain the suggestionof the pharmacist
  • 23. COMMON ANTISEPTICS : • ALCOHOLS: (surgical alcohol • Ethanol (60-90%) : • 1-Propanol (60-70%) : • 2- Propanol/isopropanol (70-80%)
  • 24. QUATERNARY AMMONIUM COMPOUNDS: (Quats or QAC’s) 3 BORIC ACID
  • 27. Characteristics of an ideal antiseptics :
  • 29. SIDE EFFECTS OF ANTISEPTICS :
  • 30. Other Antiseptics in Ayurveda :