3. Atropine is
solanaceous alkaloid.
It occurs in deadly
night shade plant
Atropa belladonna.
Specific
rotation of
atropine is -
22 degree.
Atropine is ester
of tropic acid.
It is hydrolyzed to
tropine and tropic
acid.
It is an
important
class of drug.
4. Eyes:
Topical atropine is used in treatment of eyes.
It is used as mydriatic to dilate pupils.
While atropine eye drops have been shown to be
effective in slowing the progression of myopia in
children in several studies.
All doses are effective. Low dose is thus
generally recommended due to less side effects.
6. Heart :
Atropine injection is used in the treatment of
bradycardia ( heart disease).
Atropine is useful in second and third degree
heart block.
Atropine has also been used in an effort to
prevent a low heart rate during intubation of
children.
7. Secretions:
It actions on the parasympathetic nervous
system inhibit salivary and mucus gland.
This drug may also used in inhibiting sweating
via sympathetic nervous system.
This can be useful in treating hyperhidrosis and
can prevent the death rate of dying patients.
.
8. Poisoning:
Atropine serves as a treatment for poisoning by
organophosphate insecticides and nerve agents by
injection such as:
I. Tubun (GA)
II. Serin (GB)
III. Soman (GD)
Atropine used to reduce the effects of poisoning by
blocking muscarinic acetylcholine receptors.
9. Dose of atropine are needed
for organophosphate
pesticide poisoning .
Optimizing oxygenation
prior to the use of atropine to
minimize the potential for
dyrhythmias.
