4. Functions
1. Ab attaches to the antigen Ab antigen complex
2. Ab attaches to the toxins Neutralises toxins
( antigens)
3. Antibody attaches to the receptor Disrupts the
function
4. Antibody attach to the pathogens Binds together
6. B cells
• B cells are also called B – lymphocytes, they
are the type of white blood cell of lymphocyte
subtype
• The function of humoral immunity component
of adaptive immune system by secreting Ab.
• B cells are specific to a single antigen
• They are useless against any other antigen.
8. Immune system and immunological
properties
“The immune system is a complex network of
cells and proteins that defends the body against
infection.”
9. Monoclonal Antibodies
“Monoclonal antibodies (mAb or moAb)
are antibodies that are made by
identical immune cells that are all clones of a
unique parent cell”.
It is an antibody produced by a single clone of
cells. Hence monoclonal Ab is a single pure type
of Ab.
10. Difference between Monoclonal Ab
and Polyclonal Ab
Polyclonal Ab Monoclonal Ab
Derived from different B lymphocytes
cell lines.
Derived from single B cell clone
Batch – batch variations affecting Ab
reactivity & treatments.
No batch – batch variation.
Effectivness of Ab is predictable.
Not powerful tool for clinical
diagnostic test.
Enables the development of secure
immune assay systems.
