Nutrigenomics

1. Nutrigenomics: The Latest
Area of Nutrition Research
R. T. Patil
Director, CIPHET, Ludhiana

2. • Nutrigenomics is the science of how your genes
interact with nutrients. It is the study of how DNA and
your genetic code affect your need for certain
nutrients and help maintain optimal health throughout
your life.
• How phytonutrients affect gene expression-
developing personalized nutrition solutions for you –
based upon your specific DNA.
• Personalized health and wellness at its most
fundamental, focused on your individual needs based
on your DNA and genetic code.

3. • Nutrigenomics will ultimately enable personalised
dietary advice, it is a science still in its infancy and its
contribution to public health over the next decade is
thought to be major.
• Diet is determined by the specific demands of your
genetic signature and perfectly balances your micro-
and macro-nutrient needs
• Population whose cholesterol count doesn't react
much to diet, They will be able to go ahead and eat
lots of meat.
• Vitamin supplements may not be required; take only
the vitamins you need, in precisely the right doses

4. • diet is a big factor in chronic disease, responsible, for
a third of most types of cancer. Dietary chemicals
change the expression of one's genes and even the
genome itself.
• the influence of diet on health depends on an
individual's genetic makeup.
• biologically, when we eat a meal. Food is
metabolised to provide energy for the cell. Most
dietary chemicals don't get metabolised at all;
instead, the moment they're ingested, they peel off
and become molecules that bind to proteins involved
in "turning on" certain genes to one degree or
another.

5. • A diet that's particularly out of balance, will cause
gene expressions that push us toward chronic illness
unless a precisely-tailored "intelligent diet" is
employed to restore the equilibrium.
• Why two people eating the same diet can respond
very differently - one maintaining weight, for example,
and the other ballooning
• Certain populations have variants that, when
presented with western-type food (fatty and
overprocessed and high in calories) pushes them
toward disease rather than health."

6. • You prick your finger, draw a little blood and send it,
with $100, to a consumer genomics lab. There, it's
passed through a mass spectrometer for protein
analysis and cross-referenced to your DNA profile
that will decide your recommended diet.
• The people who will benefit from customised
nutritional packets will be the 20% at either end:
those at the top who don't have to worry much about
what they eat and at the bottom, who respond
disastrously to conventional diets and will discover
that they need to follow special diets or eat specific
supplements.
What your genes want you to eat

7. Thank You