2. INTRODUCTION
Dengue fever is a
painful debilitating
mosquito born
disease caused by
any one of four
closely related
dengue virus
3. DEFINITION
Dengue fever is transmitted by the bite of an
Aedes mosquito infected with a dengue
virus. The mosquito becomes infected when
it bites a person with dengue virus in
their blood. It canât be spread directly from
one person to another person.
4. DEFINITION
⢠Dengue fever is also known as breakbone fever
is a mosquito born tropical disease caused by
the mosquito bite.
⢠The alternative name for dengue, "breakbone
fever", comes from the associated muscle and
joint pains.
⢠It is caused by the female aedes aegypti
mosquito bite, which transmit the dengue virus
to human.
5. INCIDENCE
ďźEach year an estimated 100 millions
cases of dengue occur world wide.
⢠The global incidence of dengue has
grown dramatically in recent decades.
⢠In INDIA the cases has increase sharply
over past five years there have been
38,000 so far in 2013.
10. Febrile Phase x 7days
ďźHigh fever 40 °C (104 °F)
ďźheadache
ďźgeneralized arthalgia
ďźmyalgia
ďźpetechiae
ďźbleeding from mucus membrane.
ďźA rash occurs in 50â80%
11. Critical Phase x 2days
ďźLeukopenia
ďźthrombocytopenia.
ďźIncrease capillary permeability
leading to plasma leakage that lead
to metabolic acidosis.
ďźIn children febrile phase is common
carries nausea, vomiting,
thrombocytopnea.
12. Recovery phase x 2-3 days
ďźStabilize hemodynamic status
ďźincrease urine output
ďźoverall clinical improvement.
ďźIncrease in fluid overload can cause
cerebral edema.
13.
14. SIGN & SYMPTOMS
⢠Fever ( more than 105 )
⢠Headache
⢠Muscle, joint pain
⢠skin rash ( appear 4-5 days after fever )
⢠Pain behind eyes
⢠Nausea
⢠Vomiting
⢠Mild bleeding
15.
16. WARNING SIGNS
⢠Severe abdominal pain
⢠Persistent vomiting
⢠Vomit with blood
⢠Drowsiness or irritability
⢠Dyspnoea
⢠Swollen lymph node
⢠Prostration
⢠diarrhea
17. Dengue with warning signs
⢠Probable dengue plus one of:
⢠Abdominal pain or tenderness
⢠Persistent vomiting
⢠Signs of fluid accumulation, e.g. pleural effusion or
⢠ascites
⢠Mucosal bleed
⢠Lethargy
⢠Hepatomegaly > 2 cm
⢠Rapid increase in haematocrit with fall in platelet
⢠count
⢠Needs medical intervention, e.g. intravenous fluid
18. ⢠Severe dengue
⢠⢠Severe plasma leakage leading to:
⢠Shock (dengue shock syndrome)
⢠Fluid accumulation with respiratory distress
⢠⢠Severe haemorrhagic manifestations, e.g. GI
⢠haemorrhage
⢠⢠Severe organ involvement:
⢠Liver AST or ALT ⼠1000U/L
⢠CNS: impaired consciousness
⢠Cardiomyopathy
⢠Other organs, e.g. renal impairment
⢠Needs emergency medical treatment and specialist care with
23. WHO-proposed clinical
definition of dengue
PROBABLE DENGUE
⢠⢠Exposure in an endemic area
⢠⢠Fever
Two of:
⢠Nausea/vomiting
⢠Rash
⢠Aches/pains
⢠Positive tourniquet test
⢠Leucopenia
⢠Any warning sign
⢠Laboratory confirmation important
⢠Needs regular medical observation and
instruction in the
warning signs
⢠If there are no warning signs,
need for hospitalisation is
⢠influenced by age,
comorbidities, pregnancy and
social factors
24.
25. LABORATORY FEATURES
⢠include leucopenia, neutropenia, thrombocytopenia
⢠elevated alanine aminotransferase (ALT) or
aspartate aminotransferase (AST)
⢠serology or detection of dengue viral material in
blood by RT-PCR
26. ⢠Dengue-specific IgG and IgM ELISA { positive for IgM
antibodies on or after day 5 of the fever}
IgM ELISA has a sensitivity of 83.9â98.4% and
a specificity of 100%
Dengue 2 virus enhancement in asthmatic
and non asthmatic individual.Guzman MG,
Kouri G, Soler M, Bravo J, RodrĂguez de
La Vega A, Vazquez S, Mune M
27. ⢠Extravasation of fluid due to vascular leakage can be
detected radiologically (chest radiography for pleural
effusions, echocardiography for pericardial effusions,
ultrasonography for ascites).
[Dengue haemorrhagic fever in children:
ten years of clinical experience].MĂŠndez A,
GonzĂĄlez G
Biomedica. 2003 Jun; 23(2):180-93.
40. NURSING MANAGEMENT
⢠Increased body temperature related to infection as evidence
by vital sign monitoring.
⢠Hypovolemic shock related to hemorrhage.
⢠Fluid volume deficit related to migration of intravascular fluid
into extravascular fluid.
⢠Impaired nutrition less than body requirement related to
decreased appetite.
41.
42. PROGNOSIS
⢠For the majority of peoples the people infected with
dengue virus fever the prognosis is excellent.
⢠Although they are likely to feel very ill during first 1-2
week of acute illness.
⢠Overall the fatality rate is about 1% for all denge
fever infection.
43. COMPLICATION
⢠A small percentage of individual who have dengue fever can develop
a more serious form of disease.
⢠Dengue haemorrhagic fever and disseminated intravascular
⢠coagulation
⢠Dengue shock syndrome
⢠Hepatitis, cerebral haemorrhage or oedema, encephalitis,
⢠cranial nerve palsies, rhabdomyolysis, myocarditis
⢠Vertical transmission if infection within 5 wks of delivery