2. DENGUE FEVER
• Dengue is a mosquito-borne infection caused by any one of four closely related
dengue viruses (DENV-1, -2, -3, and -4). These four viruses are called serotypes
because each has different interactions with the antibodies in human blood
serum .Infection with one serotype of DENV provides immunity to that serotype
for life, but provides no long-term immunity to other serotypes. Thus, a person
can be infected as many as four times, once with each serotype. Dengue viruses
are transmitted from person to person by Aedes mosquitoes (most often Aedes
aegypti) in the domestic environment.
3. DENGUE HEMORRHAGIC FEVER
• Dengue hemorrhagic fever (DHF): A syndrome due to the dengue virus that
tends to affect children under 10, causing abdominal
pain, hemorrhage (bleeding) and circulatory collapse (shock)
• A severe form of dengue fever, also called dengue hemorrhagic fever, can
cause severe bleeding, a sudden death
• DHF a potentially lethal complication has become a leading cause of
hospitalization and death among children's
• Sequential infection increase the risk of more serious disease results in DHF
4. TRANSMISSION
• Dengue viruses are transmitted to humans through the bite of
infective female aedes mosquitoes. It generally acquire the virus
while feeding on the blood of an infective person.
• After virus incubation for 8-10 days in mosquitos, during blood
feeding mosquito is capable, to transmitting the virus to
susceptible individual for the rest of life
• Female mosquitos also transmit the virus to their off springs by
transovarial transmission A female Aedes aegypti mosquito
obtaining a blood-meal from a human
host through her proboscis, which
penetrates the host’s skin
5. CLINICAL DIAGNOSIS
• Dengue fever is characterized by acute onset of high fever 3–14 days after the bite of
an infected mosquito.
• Symptoms include frontal headache, retro-orbital pain(behind eye balls),myalgia
(muscle pain), arthralgia(joint pain), hemorrhagic manifestations, rash, and low white
blood cell count. The patient also may complain of anorexia and nausea. Acute
symptoms, weakness, malaise, and anorexia may persist for several weeks Nausea and
vomiting ,Unusual bleeding (nose or gum bleed, small red spots under the skin, or
unusual bruising)
• Infants and young children may have a non specific febrile illness with rash
6. COMPLICATION
• High fever
• Hemorrhagic phenomenon
• Enlargement of liver
• Sever cases circulation failure
• Temp 105˚F
• Get worse day by day
7. TREATMENT
• No specific treatment for dengue virus
• Take antipyretics to control their temperature. Children with dengue are at risk for
febrile seizures during the febrile phase of illness.
• Warn patients to avoid aspirin and other nonsteroidal, anti-inflammatory
medications because they increase the risk of hemorrhage.
• If patients cannot tolerate fluids orally, they may need IV fluids. Assess
hemodynamic status frequently by checking the patient’s heart rate, capillary
refill, pulse pressure, blood pressure, and urine output.
8. PREVENTION
• Avoid infection by preventing mosquito bites.
Mosquitoes that spread dengue virus bite during the
day and night.
• Dress your child in clothing that covers arms and
legs.
• Cover strollers and baby carriers with mosquito
netting.
• Use insecticides to prevent mosquito breeding
• Vector control is implemented using management
and chemical methods