Anti Asthmatic drugs and classification , classification of asthmatic drugs , Drugs acting on the respiratory tract, Pharmacotherapy of Asthma , Asthma and Anti asthmatic drugs.

2. • These are the class of medication use
in the treatment of Bronchial Asthma
a disease ofrespiratory systemn.
• They are medications called
• Drugs acting on Respiratory system.
• Thus, Antiasthmatic drugs are
medicines that treat or prevent
asthma attacks.

3. WHAT IS ?
• Asthma is a condition in which your
airways narrow and swell and may
produce extra mucus.
• This can make breathing difficult and
trigger coughing a whistling sound
(wheezing) when you breathe out
and shortness of breath.

4. BRONCHIAL ASTHMA
• Bronchial asthma is a medical
condition which causes the airway
path of lungs to swell and narrow.
• Due to this swelling, the air path
produces excess mucus making it
hard to breathe, which results in
coughing, short breath, wheezing.
• The disease is chronic and
interferes with daily working.

5. DRUGS FOR BRONCHIAL ASTHMA
Bronchodilators
Leukotriene antagonist
Mast cell stabilizers
Corticostiroids
Anti-IgE antibody

6. ANTI-ASTHMATIC DRUGS
• 1. BROCHODILATORS
• Salbutamol
• Terbutaline
• Bambuterol
• Salmeterol
• Formoterol
• Ephedrine

7. 1.BROCHODILATORS
LONG ACTING SHORT
ACTING
• Salmeterol Salbutamol
• Formoterol Terbutaline
• Carmoterol Pirbuterol
• Olodaterol Bitolterol
• Indacterol Fenoterol
Procaterol

8. 1. BROCHODILATORS
• Theophylline (anhydrous)
• Aminophylline
• Choline theophyllinate
• Hydroxy-ethyl theophylline
• Doxophylline
• Theophylline ethanolate of piperazine

9. 1.BROCHODILATORS
• Ipratropium bromide
• Tiotropium bromide
• It is used by inhaler
or nebulizer.
• To treat asthma chronic
attack.
Nebulizer
Inhaler

10. 2. LEUKOTRIENE ANTAGONIST
• Montelukast
• Zafirlukast
• Pranlukast
• 5-lipoxygenase inhibitors
• Zileuton
• Hypericum perforatum

11. 3. MAST CELL STABILEZERS
• Prevent the degranulation of mast cells by trigger
stimuli.
• These are indicated only for prophylaxis of bronchial
asthma
• These are given by
• INHALATIONAL ROUTE
• Sodium cromoglycate
• Ketotifen
• Methylxanthines
• nedocromil

12. 4. DRUGS INHIBITING IgE ACTION
• Omalizumab is a monoclonal
antibody against IgE
• It is indicated to prevent the attack
of bronchial asthma in patients not
responding to combination of long
acting β2 agonist and a high dose of
inhalational steroid.
• It is administered by subcutanious
(S.C)route

13. 5.
• a) Systemic :
• Hydrocortisone
• Prednisolone
• b) Inhalation
• Beclomethasone
• Budesonide
• Flunisolide
• Ciclesonide

14. DRUG OF CHOICE
• Condition Drug of choice Bronchial asthma
• acute attack - Salbutamol
• acute attack in pregnancy - Salbutamol
• acute attack during labour - Ipratropium
• acute attack in patients - β-blocker
• therapy - Ipratropium
• prophylaxis - Corticosteroids

15. DRUG OF CHOICE
• Exercise induced Asthma
• acute attack - Salbutamol
• prophylaxis - Corticosteroids
• Aspirin-induced Asthma
• acute attack - Salbutamol
• prophylaxis - Corticosteroids