Differential diagnosis of depressed mood

1. Differential diagnosis of depressed mood
Major depressive
disorder
•≥2 weeks
•≥5 of 9 symptoms: depressed mood & SIGECAPS
•Significant functional impairment
•No lifetime history of mania
Persistent depressive
disorder (dysthymia)
•Chronic depressed mood ≥2 years
•≥2 of the following: appetite disturbance, sleep disturbance,
low energy, low self-esteem, poor concentration,
hopelessness
Adjustment disorder
with depressed mood
•Onset within 3 months of identifiable stressor
•Marked distress &/or functional impairment
•Does not meet criteria for another DSM-5 disorder
Normal stress response
•Not excessive or out of proportion to severity of stressor
•No significant functional impairment
SIGECAPS = Sleep disturbance, loss of Interest, excessive Guilt, low Energy, impaired
Concentration, Appetite disturbance, Psychomotor agitation/retardation, and Suicidal
ideation.