The hypothenar eminence contains four muscles that act on the little finger. The three primary muscles are the abductor digiti minimi, flexor digiti minimi brevis, and opponens digiti minimi. Each muscle has a specific origin, insertion, nerve supply, and action. The abductor digiti minimi abducts the little finger, the flexor digiti minimi brevis flexes the little finger, and the opponens digiti minimi flexes and rotates the fifth metacarpal bone.