This document summarizes the effects and properties of opium. It begins by stating that opium is illegal but used therapeutically, and that its primary effects on the central nervous system are analgesia, euphoria, sedation, and respiratory depression. It then lists additional CNS effects and peripheral effects. The document concludes by discussing addiction, withdrawal symptoms, tolerance mechanisms, and treatments for opium addiction such as methadone and buprenorphine.

1. MUHAMMAD ABDULLAH
PHARM-D 9TH SEMESTER
KOHAT UNIVERSITY OF SCIENCE
AND TECHNOLOGY

2. OPIUM

3. Illegal
Therapeutic Class
CNS

5. EFFECTS ON CNS
•ANALGESIC
•EUPHORIC
•SEDATION
•RESPIRATORY DEPRESSION
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6. EFFECTS ON CNS
•CVS DEPRESSION
•COUGH SUPPRESSION
•MIOSIS
•N AND V

7. PERIPHERAL EFFECTS
•GIT (REDUCED MOTILITY)
•RENAL FUNCTION DEPRESSION
•UTRUS
•PRURITIS AND ITCHING

8. Addiction
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9. WITHDRAWAL SYMPTOMS
• RHINORRHEA
• LACRIMATION
• YAWNING
• CHILLS
• GOOSEFLESH (GOOSEBUMPS)

10. WITHDRAWAL SYMPTOMS
• MUSCLE ACHES
• HYPERTHERMIA
• VOMITING , DIARRHEA
• ANXIETY
• HOSTILITY

11. TOLERANCE MECHANISM
•RECEPTOR RECYCLING
•RECEPTOR DOWN-REGULATION

12. TREATMENT
• METHADONE
• BUPREONORPHINE
• FOLLOW BY AND CONCURRENT WAYS OF THERAPY
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