Opium as an addictive drugs

1. MUHAMMAD ABDULLAH
PHARM-D 9TH SEMESTER
KOHAT UNIVERSITY OF SCIENCE
AND TECHNOLOGY

2. OPIUM

3. Illegal
Therapeutic Class
CNS

5. EFFECTS ON CNS
•ANALGESIC
•EUPHORIC
•SEDATION
•RESPIRATORY DEPRESSION
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6. EFFECTS ON CNS
•CVS DEPRESSION
•COUGH SUPPRESSION
•MIOSIS
•N AND V

7. PERIPHERAL EFFECTS
•GIT (REDUCED MOTILITY)
•RENAL FUNCTION DEPRESSION
•UTRUS
•PRURITIS AND ITCHING

8. Addiction
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9. WITHDRAWAL SYMPTOMS
• RHINORRHEA
• LACRIMATION
• YAWNING
• CHILLS
• GOOSEFLESH (GOOSEBUMPS)

10. WITHDRAWAL SYMPTOMS
• MUSCLE ACHES
• HYPERTHERMIA
• VOMITING , DIARRHEA
• ANXIETY
• HOSTILITY

11. TOLERANCE MECHANISM
•RECEPTOR RECYCLING
•RECEPTOR DOWN-REGULATION

12. TREATMENT
• METHADONE
• BUPREONORPHINE
• FOLLOW BY AND CONCURRENT WAYS OF THERAPY
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