Immune system waseem

1. HAFIZ M WASEEM
Immunology
Lecture 1: Immune system
1)Vaccine was first discovered by...........in 1796.
a) Thucydides b) Edward Jenner
c)Pasteur d)Robert Koch
2)Which cells recognize the foreign antigenson the surface of
cells ,organisms or tissues.....
a)B cells b)T cells
c)Antibody cells d)None

2. 3)1-Primary lymphoidorgan is:
a)-Spleen
b)-Lymph node
c)- Thymus
d)-Bone marrow
4)Which one is not a secondry lymphoidorgan:
a)-Spleen
b)-Lymph node
c)-Thymus
d)-All
5)Immunity can be lifelongin:
a).Influenza
b).Intestinal infection
c).Oral Polio vaccine
d)Tetanustaxoid
6) In Naturalacquired active immunity,
Immunity may be lifelong in _______or temporary in
_________

3. a) Mumps, influenza. b) Small pox, polio
c) Intestinal infection, hepatitis. d) none of these
7) In Natruallyacquired passive immunity , immunity is usually
short lived:
a) weeks to months b) days to weeks
c) weeks to years. d) more than 1 year
8)A preparationcontainingmaterial which may consist of dead
microorganisms called
a) vaccination b) antibodiesc) WBC's d) none of them
9)Who devised a vaccine against cholera in chickens, and
developedrabies vaccine ?
a)Robert koch
b)Louis pasture
c)Emil von
d)Paul ehrlich
10)-----------------discovered that the serum of vaccinated
individualscontainedsubstances which they called antibodies?
a)Emil von Behring
b)ShibasaburoKitasato
c)Louis Pasteur
d) A and B

4. 11) A "nonself" substance that can provoke an immune
response is calledan __________.
a)Antibody
b)Antigen
c)Interferon
d)Immunoglobulin
12)............ are major class of pattern recognition receptors
found in all coelomates.
a) Effectors
b) Receptors
c) Toll-like receptors
d) Normal receptors.
13) Complement System support productionof peptides
that......
a) Attract Immune Cells,
b)Increase vascular permeability,
c)Opsonize the surface of a pathogens.
d) All given options.
14) Passive immunity include
a) Natural immunity
b)Aquired immunity

5. c) Humoral immunity
d)Both a and b
15)MHC factor and peptide attached on the surface of
_____cells
a)B cells
b)T cells
c)G cells
d)both a and b
16) Generalized , act early , havinglimited specificity and first
line of defense are characteristics of
a)Innate immune system
b)Specific immune system
c)Non-specific immune system
d)Both a and c
17)Recruiting immune cells to sites of infection and
inflammation
a)Innate immune system
b)Immune system
c)Aquired immunity
d)Passsive immunity

6. 18) Cowpox inducedprotection against human small pox was
discovered in year:
a)1679
b)1796
c)1967
d)1888
19)Which of the followingis not anatomicalbarriers
a)Waxy cutical
b)Exoskeleton of insect
c)pH
d)Skin
20) Louis Pasteur in 1880 devised a vaccine against __________
in chickens, and developed ________ vaccine.
a) Cholera, Pneumonia b) Rabies, Pneumonia
c) Cholera, Rabies d) Rabies, Polio
21) ________ explain the specificity of the antigen-antibody
reaction.

7. a) Specific chain theory b) Side chain theory
c) Specific antigen theory d) Specificity theory
22)B lymphocyteswhich make different types of antibodiesare
about:
a)5 million
b)10 million
c)15 million
d)20 million
23)Basophilsexpress ------ on cell surface which on activation
release -----.?
a)HSC's , histadine. b)FcR, Histamine
c)T-cells, plasma B cells. d) Erythroid cell, Histocytes.
24)The functions of Innate immune system are all, except
a)-recruition of immune cells
b) inhibit Adaptive immune system
c)foreign substances undentificationand removal
d)None
25)Robert koch got Nobel prize in —.
a) 1904
b) 1905

8. c) 1906
d) 1907
26)Self renewing hematopoieticstem cell give rise to:
a) Dendritic cell
b) Mycloid progenitor
c)Lymphoid progenitor
d)Both b and c
27) Which enzymes involvephysiologicalbarries ?
a)lysozymes ,
b)-hydrolases
c)-phophsolipases
d)-a,c
28)How many types of passive immunity?
a)3
b)1
c)2
d)4
29)Innate immune system is
a)non specific b)limitedspecific

9. c) highly specific. d)both 1and2
30)When any phathogenenter into body the adaptiveimmune
response star
a)very early b) early
c) Late d) immediate
31)Pattern recognition receptors are present in
a)AnatomicalBerriers
b)phisiological Berriers*
c)Inflamatory Berriers
d)cells
32)During immune dysfunction.......................causes blood
vessels to widen and become leaky
a)desloratadine
b)histamine
c)choline
d)luteolin
33)A preparation containingantigenic material is called
a)Serum
b) Vaccine

10. c) Nutrient.
d) Suspension
34)Antigen recognition is by
a)MHF
b)BCR
c)FcR
d) None of these.