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2. It is an acute bacterial infection of the
respiratory tract caused by Bordetella pertussis .
It is also known as whooping cough due to a
characteristic sound produced during coughing.
3. Pertussis is caused by Bordetella
pertussis. It is a a gram negative
negative bacteria. The bacteria
survives only for very short
periods outside the human
body.
4. Source of infection of pertussis is a patient of
pertussis and mode of transmission is droplet
infection and direct contact. Incubation period
is 7 – 14 days.
5. pertussis produces a local infection and causes
inflammation and necrosis of the mucosa leading to
secondary bacterial invasion. Based on sign and symptoms
pertussis have 3 stages-
(a) catarrhal stage
(b) paroxysmal stage
(c) convalescent stage
6. This stage is characterized by common cold like
symptoms such as lacrimation, sneezing, coryza,
anorexia, malaise and mild cough. This stage
lasts up to 10 days
7. paroxysmal stage is characterized by bursts of rapid,
consecutive coughs followed by a deep, high-pitched
inspiration (whoop). It is usually followed by
vomiting. In young infants it may cause cyanosis and
apnoea. This stage lasts up to 2-4 weeks
8. This stage begins approximately 4 weeks after
onset of disease and lasts for 1-2 weeks. Slow
recovery starts in this phase. Episodes of
coughing becomes less frequent in this stage.
9. Complications occur in 5-6 per cent of cases,
most frequently in infants aged less than 6
months. The chief complications of pertussis are
bronchitis; bronchopneumonia.and
bronchiectasis.
10. Presence of sign and symptoms indicates
pertussis.
For confirmation nose or throat sab culture test
is done.
Complete Blood count is also done
11. Medical management of pertussis includes use
of antibiotics such as erythromycin, ampicillin,
septran or tetracycline. erythromycin is the
drug of choice in the treatment of pertussis.
12. Immunization is the most rational approach to
pertussis control. It is available in combination
as DPT or pentavalent vaccine. It is included in
national immunization schedule in India.
13. Health education regarding routine immunization
play an important role in preventing vaccine
preventable diseases including pertussis.
Notification and reporting of pertussis to authorities
is another important measure to prevent spread of
pertussis in community.
14. Isolation of the patient till the period of
infectivity is also a good preventive measure.
During epidemics protection of health workers
through chemoprophylaxis is also considered.