This Technology Innovation Alert Report by DexPatent gives you a thorough and comprehensive analysis of all patents published, granted or expired by companies, start-ups, inventors or universities across the world during the month of April 2019. This Exclusive report provides you patent and technology insights which help you to take direct decisions relating to R&D alignment, licensing or acquisition and saves a lot of time of your in-house IP and R&D team To get in-depth analysis of innovations and opportunities relating to Smart pills for Gastrointestinal tract, Please contact us at linda@dexpatent.com. The report helps you to understand the gist of each important patent just by a glance.

1. Technology Innovation Alert
Smart pill for
gastrointestinal tract
April 2019

2. Benefits of this Report
Technology Innovation Alert – Smart pill for gastrointestinal tract
• To get a complete information on patents published or granted in the given
technology
• To identify opportunities of patent/business acquisition and licensing
• To stay updated on R&D and Patenting activities of competitors and align your
plans based on real time information
• Save time of in-house IP team and R&D team
• The report is researched and designed by experts at DexPatent to help you to
get the gist of each critical patent just by a glance
• Save Time, Save Cost and Remain Up-to-date
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3. Technology Innovation Alert – Smart pill for gastrointestinal tract
• Smart pill is a medical device with small embedded
electronic appliances such as sensors, cameras and
trackers
• This electronic device is a wireless and ingestible
capsule that measures pressure, pH and temperature
data and wirelessly transmits that information
• It provides physicians with data for gastric emptying time, combined small/large
bowel transit time and whole gut transit time
• The Smartpill procedure requires only a short 15-30 minute office visit after which
you can return to your daily activities
• With Smartpill, there is no exposure to radiation and no hospital visit required as
with traditional test methods
Smart Pill
3

4. Highlights
Technology Innovation Alert – Smart pill for gastrointestinal tract
4
United States
Most active jurisdiction
Smart pill for gastrointestinal tract
1. Capsule endoscope
2. Swallowable electronics
Interesting innovation
Appetite suppressing
vibration capsule
Grant7
Application5
Inactive1
April
2019

5. Highlights
Technology Innovation Alert – Smart pill for gastrointestinal tract
Key players
5
Start-ups
• Rani Therapeutics
• Ancon Medical Technologies
Small and Medium Enterprises
• Capso Vision
• InCube Labs
• Ankon medical tech
• Pop Test Abuse
Deterrent Technology Volkmar christian
Individual Inventor
Universities / Research Centers
• Massachusetts Institute
of Technology
• Dalian University of
Technology
Large companies
• IBM
• STMicroelectronics
• Shenzhen Zifu Medical
Technology

6. Highlights
Technology Innovation Alert – Smart pill for gastrointestinal tract
Geographical distribution of
innovations
United
States
(5)
China
(3)
Europe
(2)
6
Germany
(1)
Japan
(1)
Korea
(1)

7. Problems and proposed solutions
Technology Innovation Alert – Smart pill for gastrointestinal tract
7
Many new drugs cannot be given
orally, poor oral toleration and poor
absorption of the drugs
Improved method for delivery of drugs
directly within the GI tract
Intravenous and intramuscular
delivery have pain and risk of
infection from needle stick
Reducing risk of pain and infection
from needle stick
Limited battery lifespan impact the
completion rates of the evaluation
Wireless charging technology helps to
improve the completion rates of the
evaluation

8. Problems and proposed solutions
Technology Innovation Alert – Smart pill for gastrointestinal tract
8
Invasive treatments fails to invoke
the satiety signal pathways
Stimulate satiety signals and/or appetite
suppression signals to suppress appetite
Real-time position of GI tract
cannot be accurately determined
and navigated
Efficient diagnosis and accurate active
navigation of GI tract

9. Highlights
Technology Innovation Alert – Smart pill for gastrointestinal tract
Technologies of smart pill for gastrointestinal tract
9
• Capsule camera
• Image capturing
• Image comparing
• Displaying unit
• Location sensor
• Movement sensor
• Image processing
• Visual navigation
• Endoscopic capsule
• Drug delivery means
• Physiological sensor
• Communication control
• Ingestible electronics
• Orientation adjustment
• Drug storage reservoir
• Drug dispensing control
• Producing electrical signal
• Vibration to digestive tract
• Iso-density capsule endoscope
• Electrical stimulation of L-cells
• Double hemispherical capsule robot
• Permanent magnetic dipole movement
control
• Drug deliver based on authentication
from user

10. Technology Innovation Alert – Smart pill for gastrointestinal tract
Overview of Key Patents
10

11. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
U S 2 0 1 9 0 1 0 4 9 7 9 1
Innovation Involves
A piezoelectric element disposed on
dissolvable capsule to sense the physiologic
and pathophysiologic state of a patient
gastrointestinal tract.
11
DexPatent Abstract
Ingestible electronic capsule
✓ Ingestible electronics
✓ Physiological sensor
✓ Producing electrical signal in
response to deformation
University

12. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
Vibration capsule
K R 2 0 1 9 0 0 3 4 4 9 8
A vibration capsule helps to reduce the
absorption of food and body weight of a
patient by vibrating the digestive tract,
wherein the capsule includes a motion
generation unit, a movement control unit, a
wireless communication unit and a power
supply unit.
4
Innovation Involves
12
DexPatent Abstract
✓ Vibration to the digestive tract
✓ Capsule motion control
✓ Communication control
Small and Medium enterprises

13. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
Capsule robot
C N 1 0 9 6 2 0 1 0 8
A double hemispherical capsule robot uses
visual navigation, universal rotating magnetic
field and attitude information to determine
centroid of the dark region of the intestine
image.
Innovation Involves
13
DexPatent Abstract
University
✓ Visual navigation
✓ Double hemispherical capsule
robot
0

14. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
E P 3 4 6 6 4 3 8
A swallowable capsule to treat diabetes by
electrically stimulating cells in GI track , the
capsule comprising an electrode to
electrically stimulate the track, a sensor to
sense property of the track to determine
location of the capsule and a controller to
control electrode and sensor.
Innovation Involves
14
DexPatent Abstract
Swallowable capsule
✓ Electrical stimulation of L-cells
✓ Sense activity of GI track
✓ Monitor location of capsule
15
Small and Medium enterprises

15. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
15
C N 1 0 9 5 8 9 0 8 5 0
Method for checking digestive tract using
iso-density capsule endoscope, which
includes a camera unit to inspect digestive
tract, a magnetic control means to guides
the capsule endoscope and a motion
sensor to adjust movement of the capsule
endoscope.
✓ Iso-density capsule endoscope
✓ Image capturing
✓ Movement adjustment using
sensor
Shenzhen Zifu Medical Technology
Capsule endoscopy
Large Company

16. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
U S 1 0 2 6 0 8 7 6 3
Innovation Involves
A capsule endoscopy system comprises an
imaging means to capture image, a
gyroscope to indicate orientation of image
axis and an external unit to process and
display images of GI tract.
16
DexPatent Abstract
Capsule endoscope
✓ Image capturing
✓ Orientation adjustment
✓ Image processing
✓ Displaying unit
Large Company

17. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
U S 1 0 2 5 2 0 3 9
A swallowable device includes a capsule and
a actuator for delivering drugs or therapeutic
agents within the GI tract for efficient
absorption of the drug.
Innovation Involves
17
DexPatent Abstract
Start-Up company
Swallowable drug delivery device
✓ Drug deliver means
✓ Actuator
103

18. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
Smart pill
U S 1 0 2 6 4 9 7 2
A smart pill includes a controller, a dispenser,
and a reservoir housing drug, wherein the
smart pill is communicatively connected to
user device for transmitting and receiving
secure communications to release the drug
in specific location of intestinal tract.
Innovation Involves
18
DexPatent Abstract
Large Company
✓ Drug dispensing control
✓ Drug storage reservoir
✓ Communication control
2

19. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
Ingestible drug delivery device
U S 1 0 2 4 5 3 2 3
A method for treatment of withdrawal from
narcotics and subsequent prevention of
relapse of narcotic, wherein the method
comprises ingestible drug delivery device to
determine whether large intestine has
entered or whether eight hours has elapsed
since ingestion.
7
Innovation Involves
19
Pop Test Abuse Deterrent
Technology
DexPatent Abstract
✓ Drug deliver device
✓ Drug deliver based on
authentication from user
Small and Medium enterprises

20. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
Capsule endoscopy
E P 2 9 9 5 2 4 0
A suspended capsule endoscope comprises
a permanent magnetic dipole, wherein a
sphere-shaped external magnet is used to
suspend and control the movement of the
capsule endoscope at the liquid/gas interface
in the human GI track.
1
Innovation Involves
20
DexPatent Abstract
✓ Permanent magnetic dipole
movement control
Small and Medium enterprises

21. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
D E 1 0 2 0 1 2 2 0 5 5 2 5
Capsule endoscopy for study of the human
digestive tract, wherein individual motors and
camera system is controlled wirelessly via
computer system.
Innovation Involves
21
DexPatent Abstract
Individual Inventor
✓ Endoscopic capsule
✓ Image capturing system
0
Capsule endoscopy
Volkmar christian

22. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
22
Small and Medium enterprises
J P 6 5 0 1 8 0 0 0
Method for displaying target image of GI
tract which is captured using capsule
camera according to quality of image
matching.
✓ Capsule camera
✓ Image capturing
✓ Image comparing
Capsule camera

23. Patent Family Count
Technology Innovation Alert – Smart pill for gastrointestinal tract
DexPatent Abstract
Innovation Involves
Capsule endoscope
C N 1 0 6 3 7 7 2 1 8
A twin-lens capsule endoscope comprises a
working circuit board which is integrated with
endoscope shell and image acquisition
module to diagnose gastrointestinal
diseases.
Innovation Involves
23
Jinshan Science & Technology
DexPatent Abstract
Large Company
0
Rejection of invention patent
application after publication
Legal Status
✓ Twin lens endoscope
✓ Image capturing

24. Our Services
Technology Innovation Alert – Smart pill for gastrointestinal tract
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Technology Innovation Alert – Smart pill for gastrointestinal tract
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