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Surface Coating Technology
๏ฌ Change surface chemistry without changing mechanical
properties;
๏ฌ Alter binding properties for proteins and other molecules
to improve device performance;
๏ฌ Surface coating technology increases range of
performance and, in general, requires less capital
investment and less dramatic changes in manufacturing
practices.
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Methods
๏ฌ Plasma or corona treatment in the presence
of a reactive atmosphere;
๏ฌ Adsorption; and,
๏ฌ Covalent Immobilization
The objective is to create a minimally reactive
surface by creating an interface that is
invisible to the system or one that is
specifically activated to control cell behavior
at the interface.
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Surface Modification Using Low-
Pressure Plasma Technology
โข A plasma is a partially ionized gas containing ions,
electrons, atoms, and neutral species.
โข Although many gases can be used, commonly selected
gases or mixtures of gases for plasma treatment of
polymers include oxygen, argon, nitrous oxide,
tetrafluoromethane, and air.
โข high-frequency generator ionizes the gas into plasma
that formed reactive particles react in a direct way with the
surface without damaging the bulk properties of the treated
part, the surface modification is limited to the outermost 10
to 1000 ร of the substrate.
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PLASMA APPLICATIONS
Surface modification using gas plasma is a versatile process,
with systems on the market capable of treating everything
from small components like hubs or balloons up to very large
and complex substrates, from fibers, nonwovens, wovens,
and paper to plastic foils and metal and ceramic parts
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Emerging Technologies
๏ฌ Coatings for enhanced imaging
๏ฌ Cell coated grafts for tissue engineering
๏ฌ Coating to enhance regenerative processes
๏ฌ Coatings for drug delivery
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Coating Companies
Polymer Technology Group
SurModics
Carmeda
Hydromer Inc.
AST Products Inc.
STS Biopolymers
Biocoat
Richard James Inc.
Biocompatibles Ltd.
BioChrom
Surface Solutions Laboratories
Spire Corp.
Implant Sciences Corp.
Advanced Polymer Systems Inc.
