This document introduces work package two (WP2) which focuses on advanced manufacturing and after sales service supply chain design. WP2 will examine strategic supply chain design decisions like the optimal number of echelons, resource positioning, and resource allocation while accounting for costs and demand. It will also analyze more technical aspects like minimal repair and level of repair analysis. WP2 will build upon work from package one on product and process characteristics and work with package three on inventory theory evaluation. An example problem presented is a facility location model to determine when and where to invest in additive manufacturing technology for spare parts production over time. The results of this model would depend on the input parameters and specify uncertainty in additive manufacturing development.