Enamel is the hardest tissue in the body. It is formed by cells called ameloblasts secreting enamel matrix proteins. Enamel cannot renew itself because the ameloblasts are only present during tooth development. Enamel acquires a complex structural organization and high mineralization to compensate for this limitation. Enamel has a crystalline structure composed mainly of calcium and phosphate ions. It contains enamel rods that run from the dentin-enamel junction to the enamel surface. Enamel formation involves two stages - initial mineralization followed by maturation where the crystals grow in size.
6. …To COMPENSATE this inherent LIMITATION,
Acquires a COMPLEX STRUCTURAL ORGANIZATION
& HIGH DEGREE OF MINERALISATION
(by almost total absence of in its mature state)
enamel
Dr.Shubhangi
27. Do you remember
in Advanced Bell Stage ?
Inner Enamel Epithelium
Dr.Shubhangi
28. Advanced Bell Stage
Odontoblasts
Thin layer of dentin
Inner Enamel Epithelium
We secreted
some dentinal
matrix Now,
you START
secreting
ENAMEL matrix
OKAY! We
will change
into TALL
ameloblasts
now!
Dr.Shubhangi
29. Advanced Bell Stage
Odontoblasts
Thin layer of dentin
AMELOBLASTS
Just like we
did. At the
CUSP first!
Then move
downwards to
cervical area!
But, from
where should
we start
depositing
ENAMEL
MATRIX ?
Dr.Shubhangi
36. I will interact with
adjacent mesenchymal
cells and determine the
shape of DEJ and crown
Dr.Shubhangi
37. I will interact with
adjacent mesenchymal
cells and determine the
shape of DEJ and crown
Dr.Shubhangi
38. I will keep
interacting with
adjacent
mesenchymal cells
and feed them
with some proteins
(like enamel
matrix), till they
agree to become
Odontoblasts!
Dr.Shubhangi
39. I will keep
interacting with
adjacent
mesenchymal cells
and feed them
with some proteins
(like enamel
matrix), till they
agree to become
Odontoblasts!
Dr.Shubhangi