2. Chancroid :
It is an acute STD characterized by a
painful ulcer at the site of inoculation
and development of suppurative
regional lymphadenopathy.
2
3. Chancroid :
Etiology : Hemophilus ducreyi , a gram –ve
streptobacillus.
High incidence of HIV infection in patients
with chancroid . Known to enhance infection
rate.
Incubation period : 4 to 7 days.
Endemic in tropical 3rd world countries.
3
4. Skin lesion
Initially tender papule that
evolves to pustule,
erosion and ulcer.
Ulcer is quite tender and
painful.
Borders are sharp
undermined and not
indurated.
Base of ulcer covered
with gray to yellow
exudate.
4
7. Skin lesions :
Ulcers may be single or multiple or merge to
form large ulcers.
Suppurative Lymphadenopathy ,painful,
(usually unilateral) occur within 1 to 2 weeks
of the lesion.
Buboes may drain spontaneously.
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8. Investigations :
Gram stain: Scrapings from base of ulcer may
show clusters of gram negative rods
(SCHOOL OF FISH).
Culture : Difficult, special media, Sensitivity
< 80%.
Serologic tests : None, Should be tested for
syphilis and HIV. Repeat after 3 months if –
ve initially.
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9. Management :
Azithromycin : 1 gm Single dose.
Inj. Ceftriaxone : 250 mg IM single dose.
Ciprofloxacin : 500mg bid for 3 days.
Reexamination after 3 to 7 days.
Buboes may need to be aspirated.
9
10. Complications :
Large inguinal abscess may develop & rupture to form
draining sinus or giant ulcer
Superinfection by Fusarium & Bacteroides
Phimosis- in long standing lesions