1. Haemoglobin, Mioglobin and Binding
Mechanism of Oxygen
Asni Ramdani

2. HAEMOGLOBIN
MIOGLOBIN

3. Hemoglobin
4 globular
protein
2 sub unit α
2 sub unit β
Hemoglobin A (HbA)
4
Heme Group

4. The totality of
amino acid in
hemoglobin :
• Sub unit α :
141 residue
• Sub unit β :
146 residue

7. N
1
5
N
4
Fe
2
N
6
3
N
6
2
1
3
4
5

16.  As
stabilisator of deoksihemoglobin status (T
status)
 Created 1 more “jembatan garam”

20. Outline of Bohr effect
CO2 + H2O
H2CO3, H2CO3 unravel into proton and ions bikarbonat.
In the lungs, binding of oxygen by hemoglobin will release protons from
hemoglobin.