4. INTRODUCTION
The lens of the eye is a transparent,
biconvex, elliptical, semi solid,
avascular body of crystalline
appearance located between the iris
and the vitreous.
Weight of lens varies with age.
5. Equatorial diameter 6.5 mm at
birth, increases to 9 to 10 mm in
the second decade and then
remain almost constant.
6. Thickness (axial or anterioposterior
diameter ) varies with age between 3.5 mm
(at birth ), about 4 mm at 40 years and
increase slowly to 4.75 to 5 mm in extreme
old age.
The weight is approximately 260 mg at 70 -
80 years of age.
In males, the lens weight more than the
aged matched females, with a mean
difference of 7.9 to 2.47 mg.
8. It is less convex than the posterior
surface.
The anterior surface is the segment
of a sphere whose radius average 10
mm.
The center of anterior surface is
known as the anterior pole, and is
about 3 mm from the back of the
cornea.
ANTERIOR SURFACE
9. It is more curved than the anterior
and present a radius of about 6
mm (4.5-7.5) .
The centre of posterior surface is
called as posterior pole.
It lies in a fossa lined by the
hyaloid membrane on the front of
the vitreous.
POSTERIOR SURFACE
10. REFRACTIVE INDEX
The refractive index of the lens is 1.39 (
nucleus 1.42, cortex 1.38 ) , which is
slightly more than that of the aqueous (
1.336 ) and vitreous humor ( 1.3349 ).
The refractive power is about 16 – 17
dioptres, out of a total of about 60 diopters
for the normal eye.
11. Accommodative power is 15 - 16 diopters,
diminishing to half of this at about 25 years of
age and to 2 diopters or less at age 50 years.
12. Structure
The lens consists of –
1. The lens capsule
2. The lens epithelium and
3. The lens cells or fibers
STRUCTURE
13.
14. LENS CAPSULE
It is a thin, transparent, hyaline
collagenous membrane which
surrounds the lens completely.
The lens capsule is highly elastic
but does not contain any elastic
tissue.
15. CHARACTERISTICS OF THE LENS CAPSULE
The capsule completely envelops
the lens and the cells of origin are
completely contained in it.
The capsule is the basement
membrane of the lens epithelium
and is the thickest basement
membrane of the body.
16. It is much thicker in front than behind and the
anterior and posterior portions are thicker towards
the periphery ( equator ) just within the attachment
of the suspensory ligament than at the poles.
17. The thickness at the posterior pole is 2.8 – 4
microne meter and at anterior pole is 15.5
microne meter.
Capsule thickness increase anteriorly with
age.
Under the light microscope the
capsule appears transparent,
homogenous.
ON MICROSCOPES
18. However, on ultramicropic
examination, it shows a lamellar
appearance.
Under electron microscope the
capsule appears to have a relatively
amorphous appearance.
There are up to 40 lamellae each of
which is 40 mm thick.
19. THE LENS EPITHELIUM
The lens epithelium consists of a
single shut of cuboidal cells spread
over the front of the lens, deep to the
capsule and extending outwards to the
equator.
There are about 500,000 cells in the
mature lens.
There cells contain all the organelles
found in a typical epithelium cell.
20. Almost all the metabolic, synthetic and transport
process of the lens occur in this layer.
EQUATOR
21. ZONES OF LENS EPITHELIUM
There are 3 zones in the lens
epithelium.
The central zone represents a stable
population of cells.
The intermediate zone is peripheral to
central zone and its cells are smaller.
The germinative zone is the most
peripheral and is located just pre
equatorially.
22. FEATURES OF LENS EPITHELIUM
The highest metabolic rate occurs
in the anterior lens epithelium,
because the content of ATP and
enzymes is highest in this area of
lens.
23. THE LENS FIBRES
The epithelial cells elongate to form the lens
fibres are formed from the posterior
epithelium which runs from posterior to
anterior to fill the lens vesicle.
But later on, the lens fibres are derived from
the cells of the equatorial region of the
anterior epithelium.
These cells divide, elongate and
differentiate to produce long, thin, regularly
arranged the bulk of the lens .
25. ZONAL ARRANGEMENT OF LENS FIBRES
The lens fibres are formed throughout life
and are arranged in zones that describe the
various development periods of the lens.
a. Nucleus
b. Cortex
a) Nucleus – It is central part containing the
oldest fibres. It consists of different zones.
Embryonic nucleus is its innermost part.
(formed at 1 to 3 months of gestation )
26.
27. Fetal nucleus (corresponding to lens
from 3 months of gestation till birth)
Infantile nucleus ( corresponding to lens
from birth to puberty )
Adult nucleus (corresponding to the lens in
adult life)
b) Cortex – it is peripheral part of the lens
substance which lies just outside the adult nucleus.
It include the youngest lens fibres.
28.
29. THE CILIARY ZONULES
The ciliary zonules ( zonules
of Zinn or suspensory
ligament of lens ) consists
essentially of a series of fibres
which run from the ciliary
body and fuse into the outer
layer of the lens capsule
around the equatorial zone.
Thus, they hold the lens in
position and enable the ciliary
muscle to act on it.
30.
31. ACCOMMODATION
Accommodation is the ability to increase
the refractive power of eye by changing the
shape of the crystalline lens.
Accommodation is the process by which
one can focus the object at differences in a
bid to have a clear vision.
In humans the process of accommodation
is achieved by a change in the shape of
the lens.