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Difficult Laparoscopic Cholecystectomy-When and Where
is the Need to Convert?
Original Article
INTRODUCTION
Laparoscopic cholecystectomy has become the gold
standard treatment of symptomatic gall stone since its
inception in 1987 [1]. With the increasing experience in
laparoscopic surgery, surgeon has started to take more and
more difficult, complex and high risk cases, which were
considered relative contradictions for laparoscopic
removal of gall bladder few year back.
But it is important to know the different clinical,
radiological parameter and specific predictor that give
some prediction of difficult laparoscopic cholecystectomy,
which not only helps in patient counselling but also help
the surgeon to prepare better for intraoperative difficulties
expected to be encountered. Laparoscopic
cholecystectomy is associated with less morbidity than
open cholecystectomy if it is done successfully,
irrespective the of duration of surgery [2].
But with the growing experience and improved
technology more number of laparoscopic
cholecystectomy, even in case of so called difficult cases,
can be completed successfully and the need for conversion
to open is gradually decreasing.
METHOD
We conducted this study at our hospital and included
all laparoscopic cholecystectomy done at our hospital
from May 2008 to January 2010. Detailed clinical history
and physical examination were carried out. Complete
blood count, RBS, RFT, LFT, BT, CT, PT, Viral marker,
Urine examination and USG was done in every case.
Preoperative ERCP done in case of suspected CBD
stones. Total time taken in surgery, conversion rate and
complication rate were analysed. Factors making lap
cholecystectomy difficult were also analysed.
We defined difficult laparoscopic cholecystectomy
when we found
(i) Dense fibrotic adhesion in and around calot’s
triangle
(ii) Gangeranous gall bladder
(iii) Empyema
(iv) Large stone impacted at neck of gall bladder
(v) Contracted gallbladder
(vi) Mirrizi’s syndrome
135 Apollo Medicine, Vol. 7, No. 2, June 2010
DIFFICULT LAPAROSCOPIC CHOLECYSTECTOMY- WHEN AND WHERE IS
THE NEED TO CONVERT?
Rajesh Sinha
Consultant, Department of Surgery, Apollo BSR Hospitals, Bhilai 490 020, India.
e-mail:rajeshsinha1987@yahoo.co.in
Laparoscopic cholecystectomy has now become the treatment of choice for the gall bladder stone. With
increasing experience, surgeon has started to take more difficult cases which were considered relative contra
indications for laparoscopic removal of gall bladder few years back.
We conducted this study at our hospital and included all laparoscopic cholecystectomy done from May’08 to
January’10. Total time taken in surgery, conversion rate and complication rate were analysed. Factors making
laparoscopic cholecystectomy difficult were also analysed. We defined difficult laparoscopic cholecystectomy
when we found -dense fibrotic adhesions in and around Callot’s triangle, gangrenous gall bladder, empyma,
large stone impacted at gall bladder neck, contracted gall bladder, Mirrizi’s syndrome, h/o biliary pancreatitis,
CBD stones, acute cholecystitis of <72 hrs duration.
Out of 206 cases done during above period, 56 cases were considered difficult. Only two cases were
converted to open.
With growing experience and technical advancement surgery can be completed in most of the difficult cases.
This is important because recently it is shown in literature that laparoscopic cholecystectomy is associated
with less morbidity than open method irrespective of duration of the surgery.
Key word: Laparoscopic cholecystectomy, Difficult laparoscopic cholecystectomy, Laparoscopy,
Cholecystectomy.
Apollo Medicine, Vol. 7, No. 2, June 2010 136
Original Article
complition rate and low conversion rate in difficult cases
when surgeons are experienced and technique is little bit
modified & operative team is same [3-6].
Conversion rates can be brought down to a very low
level, if surgeon is experienced enough and if the
procedure is modified accordingly in difficult cases [7].
The most common cause of conversion to open
surgery in literature is dense adhesion at Callot’s triangle
followed Mirrizi’s syndrome [8].
Many studies also tried to find the method by which
prediction of the difficult laparoscopic cholecystectomy
can be made preoperatively [9-12], with varied degree of
success.
Some have also tried to come out with some sort of
scoring system [13,14] which can help in prediction of
difficult lap cholecystectomy. Several clinical and
radiological parameter have been identified, which can
predict the difficult laparoscopic cholecystectomy. The
clinical parameter, male sex [15-16], advanced age [14-
17], prolonged history of gall stone, leucocytosis and
systemic signs of sepsis, elevated liver enzyme are related
to difficulty encountered during the surgery.
USG finding of gall bladder wall thickness >4.0 mm
[18], procaline gallbladder, calcification in gallbladder,
large gallbladder stone can predict the difficult
laparoscopic cholecystectomy.
Predication of difficult laparoscopic cholecystectomy,
preoperatively helps in patient counselling and also helps
the surgeon to prepare both for intra operative risk and the
technical difficulties expected to be encountered [19-20].
Finally many technical modifications have been
advised for the successful completion of the laparoscopic
cholecys-tectomy in difficult cases.
Our modification in difficult cases include putting
additional trocar, use of fan shaped retractor, to retract the
stomach & duodenum, aspiration of gall bladder in case of
mucocele and empyema, use of long and tooth grasper in
case of thick walled gallbladder, blunt dissection with tip
of suction cannula, subtotal and partial cholecystectomy,
use of intra corporeal suturing in case of wide cystic duct,
separate removal of large impacted stone in hartman’s
pouch which helps in grasping the gallbladder neck.
In spite of all these methods there are the instances,
where a surgeon need to convert the surgery from
laparoscopic to open – like (a) When surgeon is
inexperienced (b) Anatomy is unclear (c) If no progress is
madeinidentifyingtheanatomyduringthesurgery[19-20].
(vii) H/o Biliary pancreatitis.
(viii)CBS stones.
(xi) Acute cholecystitis of <72 hrs duration.
We, as a policy do not operate in case of acute
cholecystitis of >72 hrs duration at 1st admission and plan
for surgery after 6-8 weeks.
RESULTS
We included 206 cases of laparoscopic
cholecystectomy done at out centre between May 2008 to
Jan 2010. Out 206 cases 50 were male 156 were female.
Out of 206 cases 56 cases were considered as difficult
laparoscopy cholecystectomy cases by our definition. Out
of 56 difficult laparoscopic cholecystectomy cases, we
were able to complete the surgery by laparoscopic method
in 54 cases and only in two cases we converted it to open.
In Both these cases the indication for conversion was
extremely friable gall bladder, which makes the gall
bladder difficult to hold. There was no significant
complication in cases where cholecystectomy was
completed successfully by laparo-scopic method. In one
of two converted cases, wound infection occurred which
was treated by dreessings & antibiotics. Average time
taken for the completion of surgery was 45 min. Average
time taken in case of difficult cases was 1.35 hrs.
DISCUSSION
Laparoscopic cholecystectomy has almost replaced
the open cholecystectomy as a treatment option of
diseased gall bladder, since Philip Mouret did the first
laparoscopic cholecystectomy as in 1987 [1].
Laparoscopic cholecystec-tomy has many advantage over
the open cholecystectomy like
(i) Minimal post operative pain
(ii) Fast recovery
(iii) Short hospital stay
(iv) Decreased morbidity
(v) Better cosmesis
(vi) Cost effectiveness.
These advantages are also there even in case of
difficult laparoscopic cholecystectomy. It has been shown
that laparoscopic cholecsystectomy if completed
successfully, is associated with less morbidity than open
cholecystectomy irrespective of total duration of the
surgery [2].
Many studies also indicates the reasonably high
Original Article
137 Apollo Medicine, Vol. 7, No. 2, June 2010
Also conversion should not be considered as a failure
or complication of the surgery rather it is a demand of the
situation and when need arises surgeon should not hesitate
to convert.
CONCLUSION
Laparoscopic Cholecystectomy is a gold standard
treatment now for the gall stone disease. The Technique
has been standardized for the laparoscopic
cholecystectomy. There are situations which give rise to
difficult laparoscopic cheoleystectomy. With experience
& little modification of technique & patience, we can
successfully complete the surgery by laparoscopic method
only, because it is shown in literature that laparoscopic
cholecystectomy is still better option than open
cholecystectomy even in case of difficult cases. But there
are situation, where there is a need to convert the surgery
to open method & it should not be considerd as failure but
a sound judgement by the surgeon.
REFERENCES
1. Mouret P. From the first laparoscopic cholecystecomy to
frontiers of laparoscopic surgery, the future perspective.
Dig. Surg. 1991;8:124-125.
2. Habib FA, Kolachalam RB, Khilnani R, et al. Role of
laparoscopic choleystecomy in the management of
gangerenous cholecystitis. Am J. surg.2001;181: 71-75.
3. Kum CK, Goh PMY, Issac JR, et al laparoscopic
cholecystectomy for acute cholecystitis. Br. J Surg 1994;
81: 1651-1654.
4. Rattner DW, Ferguson C, Warshaw AL. Factors
associated with successful laparoscopic
cholecystectomy for acute cholecystitis. Ann surg 1993;
217: 233-236.
5. Zucker KA, Bailey RW, Flowers J. Laparoscopic
management of acute and chronic cholecystitis. Surg
Clin North Am. 1992; 2: 1045-1067.
6. Faber JM, Fagot H, Domergue J, et al. Laparoscopic
cholecystectomy in complicated cholelithiasis. Surg
Endosc 1989; 3: 1198-1201.
7. Singh K, Ohri A. Laparoscopic cholecystectomy – is there
a need to convert? J Mini Access Surg. 2005; 1: 59-62.
8. Rosen M, Fred B, Jeffery P. Predictive factors for
conversion of laparoscopic choleystectomy. Am J Surg
2002;184: 254-258.
9. S Kumar, S Tiwary, N Agrawal, G Prasanna, R Khanna, A
Khanna. Predictive factors for difficult surgery in
laparoscopic cholecystectomy and chronic cholecystits.
The internal journal of surgery 2008, 6(2).
10. P Lal, P N Agarwal, V K Malik, AL Chakaravorty.A difficult
laparoscopic cholecystectomy that requires conversion
to open procedure can be predicated by preoperetive
ultra sonography. JSLS 2002; 6: 59-63.
11. Eamonn carmody, Ann-marrie Arenson, Sharif Hanna.
Failed or difficult laparoscopic cholecystectomy. Can pre
operative ultrasonography identify potential problems?
Jounral of clinical ultrasound. 22(6): 391-396.
12. J Nachnani, A Supe. Pre operative prediction of difficult
laparoscopic cholecystectomy using clinical and ultra-
sonographic parameters. Indian J Gastroenterol 2005:
24:16-18.
13. N Bulbuller, et al. Implementation of a scoring system for
Assessing difficult cholecystectomy in a single center.
Surgery Today 2006; 36(1): 37-40.
14. Kama NA, Kologlu M, Dogonay M, et al. A risk score for
conversion from laparoscopic to open cholecystectomy.
Am J Surg 2001;181:520-525
15. Alponat A, Kum CK, Koh BC, et al. Predictive factors for
conversion of laparoscopic cholecystectomy. World J
Surg. 1997; 21: 629-633.
16. Wiebke EA, Pruitt AL, Howard TJ, et al. Conversion of
laparoscopic to open Cholecystectomy. An analysis of
risk factors. Surg Endosc 1996;10 :742-745.
17. Brodsky A, Matter I, Sabo E, et al. Laparoscopic
cholecystectomy for acute cholecystitis, can the need for
conversion and the probability of conversion be
predicted? A prospective study. Surg. Endosc
2000;14:755-760.
18. Cuschiere A, Berci G. The difficult cholecystectomy. In
Cuschieri A,Berci G, eds. Laparoscopic Biliary surgery.
2nd ed. Blackwell Scientific Publications, London;
1992:101-115.
19. Subhash Khanna. How to predict difficult laparoscopic
cholecystectomy and When to convert? In Compre-
hensive Laparoscopic Surgery. IAGES. 2007; 81-89.
20. Zucker KA. Laparoscopic management of acute
cholesystitis. In Zucker KA, ed. Surgical Laparoscopy,
2nd ed. Lippincott Williams & Willkins, Philadelphia,
USA. 2001; 142-162.
Difficult Laparoscopic Cholecystectomy-When and Where is the Need to Convert?

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Difficult Laparoscopic Cholecystectomy-When and Where is the Need to Convert?

  • 1. Difficult Laparoscopic Cholecystectomy-When and Where is the Need to Convert?
  • 2. Original Article INTRODUCTION Laparoscopic cholecystectomy has become the gold standard treatment of symptomatic gall stone since its inception in 1987 [1]. With the increasing experience in laparoscopic surgery, surgeon has started to take more and more difficult, complex and high risk cases, which were considered relative contradictions for laparoscopic removal of gall bladder few year back. But it is important to know the different clinical, radiological parameter and specific predictor that give some prediction of difficult laparoscopic cholecystectomy, which not only helps in patient counselling but also help the surgeon to prepare better for intraoperative difficulties expected to be encountered. Laparoscopic cholecystectomy is associated with less morbidity than open cholecystectomy if it is done successfully, irrespective the of duration of surgery [2]. But with the growing experience and improved technology more number of laparoscopic cholecystectomy, even in case of so called difficult cases, can be completed successfully and the need for conversion to open is gradually decreasing. METHOD We conducted this study at our hospital and included all laparoscopic cholecystectomy done at our hospital from May 2008 to January 2010. Detailed clinical history and physical examination were carried out. Complete blood count, RBS, RFT, LFT, BT, CT, PT, Viral marker, Urine examination and USG was done in every case. Preoperative ERCP done in case of suspected CBD stones. Total time taken in surgery, conversion rate and complication rate were analysed. Factors making lap cholecystectomy difficult were also analysed. We defined difficult laparoscopic cholecystectomy when we found (i) Dense fibrotic adhesion in and around calot’s triangle (ii) Gangeranous gall bladder (iii) Empyema (iv) Large stone impacted at neck of gall bladder (v) Contracted gallbladder (vi) Mirrizi’s syndrome 135 Apollo Medicine, Vol. 7, No. 2, June 2010 DIFFICULT LAPAROSCOPIC CHOLECYSTECTOMY- WHEN AND WHERE IS THE NEED TO CONVERT? Rajesh Sinha Consultant, Department of Surgery, Apollo BSR Hospitals, Bhilai 490 020, India. e-mail:rajeshsinha1987@yahoo.co.in Laparoscopic cholecystectomy has now become the treatment of choice for the gall bladder stone. With increasing experience, surgeon has started to take more difficult cases which were considered relative contra indications for laparoscopic removal of gall bladder few years back. We conducted this study at our hospital and included all laparoscopic cholecystectomy done from May’08 to January’10. Total time taken in surgery, conversion rate and complication rate were analysed. Factors making laparoscopic cholecystectomy difficult were also analysed. We defined difficult laparoscopic cholecystectomy when we found -dense fibrotic adhesions in and around Callot’s triangle, gangrenous gall bladder, empyma, large stone impacted at gall bladder neck, contracted gall bladder, Mirrizi’s syndrome, h/o biliary pancreatitis, CBD stones, acute cholecystitis of <72 hrs duration. Out of 206 cases done during above period, 56 cases were considered difficult. Only two cases were converted to open. With growing experience and technical advancement surgery can be completed in most of the difficult cases. This is important because recently it is shown in literature that laparoscopic cholecystectomy is associated with less morbidity than open method irrespective of duration of the surgery. Key word: Laparoscopic cholecystectomy, Difficult laparoscopic cholecystectomy, Laparoscopy, Cholecystectomy.
  • 3. Apollo Medicine, Vol. 7, No. 2, June 2010 136 Original Article complition rate and low conversion rate in difficult cases when surgeons are experienced and technique is little bit modified & operative team is same [3-6]. Conversion rates can be brought down to a very low level, if surgeon is experienced enough and if the procedure is modified accordingly in difficult cases [7]. The most common cause of conversion to open surgery in literature is dense adhesion at Callot’s triangle followed Mirrizi’s syndrome [8]. Many studies also tried to find the method by which prediction of the difficult laparoscopic cholecystectomy can be made preoperatively [9-12], with varied degree of success. Some have also tried to come out with some sort of scoring system [13,14] which can help in prediction of difficult lap cholecystectomy. Several clinical and radiological parameter have been identified, which can predict the difficult laparoscopic cholecystectomy. The clinical parameter, male sex [15-16], advanced age [14- 17], prolonged history of gall stone, leucocytosis and systemic signs of sepsis, elevated liver enzyme are related to difficulty encountered during the surgery. USG finding of gall bladder wall thickness >4.0 mm [18], procaline gallbladder, calcification in gallbladder, large gallbladder stone can predict the difficult laparoscopic cholecystectomy. Predication of difficult laparoscopic cholecystectomy, preoperatively helps in patient counselling and also helps the surgeon to prepare both for intra operative risk and the technical difficulties expected to be encountered [19-20]. Finally many technical modifications have been advised for the successful completion of the laparoscopic cholecys-tectomy in difficult cases. Our modification in difficult cases include putting additional trocar, use of fan shaped retractor, to retract the stomach & duodenum, aspiration of gall bladder in case of mucocele and empyema, use of long and tooth grasper in case of thick walled gallbladder, blunt dissection with tip of suction cannula, subtotal and partial cholecystectomy, use of intra corporeal suturing in case of wide cystic duct, separate removal of large impacted stone in hartman’s pouch which helps in grasping the gallbladder neck. In spite of all these methods there are the instances, where a surgeon need to convert the surgery from laparoscopic to open – like (a) When surgeon is inexperienced (b) Anatomy is unclear (c) If no progress is madeinidentifyingtheanatomyduringthesurgery[19-20]. (vii) H/o Biliary pancreatitis. (viii)CBS stones. (xi) Acute cholecystitis of <72 hrs duration. We, as a policy do not operate in case of acute cholecystitis of >72 hrs duration at 1st admission and plan for surgery after 6-8 weeks. RESULTS We included 206 cases of laparoscopic cholecystectomy done at out centre between May 2008 to Jan 2010. Out 206 cases 50 were male 156 were female. Out of 206 cases 56 cases were considered as difficult laparoscopy cholecystectomy cases by our definition. Out of 56 difficult laparoscopic cholecystectomy cases, we were able to complete the surgery by laparoscopic method in 54 cases and only in two cases we converted it to open. In Both these cases the indication for conversion was extremely friable gall bladder, which makes the gall bladder difficult to hold. There was no significant complication in cases where cholecystectomy was completed successfully by laparo-scopic method. In one of two converted cases, wound infection occurred which was treated by dreessings & antibiotics. Average time taken for the completion of surgery was 45 min. Average time taken in case of difficult cases was 1.35 hrs. DISCUSSION Laparoscopic cholecystectomy has almost replaced the open cholecystectomy as a treatment option of diseased gall bladder, since Philip Mouret did the first laparoscopic cholecystectomy as in 1987 [1]. Laparoscopic cholecystec-tomy has many advantage over the open cholecystectomy like (i) Minimal post operative pain (ii) Fast recovery (iii) Short hospital stay (iv) Decreased morbidity (v) Better cosmesis (vi) Cost effectiveness. These advantages are also there even in case of difficult laparoscopic cholecystectomy. It has been shown that laparoscopic cholecsystectomy if completed successfully, is associated with less morbidity than open cholecystectomy irrespective of total duration of the surgery [2]. Many studies also indicates the reasonably high
  • 4. Original Article 137 Apollo Medicine, Vol. 7, No. 2, June 2010 Also conversion should not be considered as a failure or complication of the surgery rather it is a demand of the situation and when need arises surgeon should not hesitate to convert. CONCLUSION Laparoscopic Cholecystectomy is a gold standard treatment now for the gall stone disease. The Technique has been standardized for the laparoscopic cholecystectomy. There are situations which give rise to difficult laparoscopic cheoleystectomy. With experience & little modification of technique & patience, we can successfully complete the surgery by laparoscopic method only, because it is shown in literature that laparoscopic cholecystectomy is still better option than open cholecystectomy even in case of difficult cases. But there are situation, where there is a need to convert the surgery to open method & it should not be considerd as failure but a sound judgement by the surgeon. REFERENCES 1. Mouret P. From the first laparoscopic cholecystecomy to frontiers of laparoscopic surgery, the future perspective. Dig. Surg. 1991;8:124-125. 2. Habib FA, Kolachalam RB, Khilnani R, et al. Role of laparoscopic choleystecomy in the management of gangerenous cholecystitis. Am J. surg.2001;181: 71-75. 3. Kum CK, Goh PMY, Issac JR, et al laparoscopic cholecystectomy for acute cholecystitis. Br. J Surg 1994; 81: 1651-1654. 4. Rattner DW, Ferguson C, Warshaw AL. Factors associated with successful laparoscopic cholecystectomy for acute cholecystitis. Ann surg 1993; 217: 233-236. 5. Zucker KA, Bailey RW, Flowers J. Laparoscopic management of acute and chronic cholecystitis. Surg Clin North Am. 1992; 2: 1045-1067. 6. Faber JM, Fagot H, Domergue J, et al. Laparoscopic cholecystectomy in complicated cholelithiasis. Surg Endosc 1989; 3: 1198-1201. 7. Singh K, Ohri A. Laparoscopic cholecystectomy – is there a need to convert? J Mini Access Surg. 2005; 1: 59-62. 8. Rosen M, Fred B, Jeffery P. Predictive factors for conversion of laparoscopic choleystectomy. Am J Surg 2002;184: 254-258. 9. S Kumar, S Tiwary, N Agrawal, G Prasanna, R Khanna, A Khanna. Predictive factors for difficult surgery in laparoscopic cholecystectomy and chronic cholecystits. The internal journal of surgery 2008, 6(2). 10. P Lal, P N Agarwal, V K Malik, AL Chakaravorty.A difficult laparoscopic cholecystectomy that requires conversion to open procedure can be predicated by preoperetive ultra sonography. JSLS 2002; 6: 59-63. 11. Eamonn carmody, Ann-marrie Arenson, Sharif Hanna. Failed or difficult laparoscopic cholecystectomy. Can pre operative ultrasonography identify potential problems? Jounral of clinical ultrasound. 22(6): 391-396. 12. J Nachnani, A Supe. Pre operative prediction of difficult laparoscopic cholecystectomy using clinical and ultra- sonographic parameters. Indian J Gastroenterol 2005: 24:16-18. 13. N Bulbuller, et al. Implementation of a scoring system for Assessing difficult cholecystectomy in a single center. Surgery Today 2006; 36(1): 37-40. 14. Kama NA, Kologlu M, Dogonay M, et al. A risk score for conversion from laparoscopic to open cholecystectomy. Am J Surg 2001;181:520-525 15. Alponat A, Kum CK, Koh BC, et al. Predictive factors for conversion of laparoscopic cholecystectomy. World J Surg. 1997; 21: 629-633. 16. Wiebke EA, Pruitt AL, Howard TJ, et al. Conversion of laparoscopic to open Cholecystectomy. An analysis of risk factors. Surg Endosc 1996;10 :742-745. 17. Brodsky A, Matter I, Sabo E, et al. Laparoscopic cholecystectomy for acute cholecystitis, can the need for conversion and the probability of conversion be predicted? A prospective study. Surg. Endosc 2000;14:755-760. 18. Cuschiere A, Berci G. The difficult cholecystectomy. In Cuschieri A,Berci G, eds. Laparoscopic Biliary surgery. 2nd ed. Blackwell Scientific Publications, London; 1992:101-115. 19. Subhash Khanna. How to predict difficult laparoscopic cholecystectomy and When to convert? In Compre- hensive Laparoscopic Surgery. IAGES. 2007; 81-89. 20. Zucker KA. Laparoscopic management of acute cholesystitis. In Zucker KA, ed. Surgical Laparoscopy, 2nd ed. Lippincott Williams & Willkins, Philadelphia, USA. 2001; 142-162.