This document provides an overview of the 2021 ASHRAE Handbook - Fundamentals. It lists the contributors to the handbook and the ASHRAE technical committees involved. It also includes a table of contents showing the 41 chapters covered in the handbook, which are grouped into sections on principles, indoor environmental quality, load and energy calculations, HVAC design, building envelope, materials, and general topics. The handbook is a key reference for fundamental HVAC&R concepts and applications.