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General method of the preparation of
Bacterial Infections, Toxoids, Viral vaccine, Antitoxins,
Serum-immune blood derivatives and
other products relative to immunity.
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-1 1
CO3.1
Noida Institute of Engineering and Technology
(Pharmacy Institute) Greater Noida
Abhijit Debnath
Asst. Professor
NIET, Pharmacy
Institute
Unit: 3
Subject Name: Biotechnology
(BP605T)
Course Details
(B. Pharm 6th Sem)
General Method of
the Preparation of
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-1 2
 Bacterial infections,
 Toxoids,
 Viral vaccine,
 Antitoxins,
 Serum-immune blood derivatives and
other products relative to immunity.
CO1.1
Noida Institute of Engineering and Technology
(Pharmacy Institute) Greater Noida
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
3
 A vaccine is a biological preparation that provides
active acquired immunity to a particular
infectious disease.
 A vaccine typically contains an agent that
resembles a disease-causing microorganism and
is often made from weakened or killed forms of
the microbe, its toxins, or one of its surface
proteins.
VACCINE CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
4
 The agent stimulates the body's immune system to
recognize the agent as a threat, destroy it, and to further
recognize and destroy any of the microorganisms
associated with that agent that it may encounter in the
future. Vaccines can be prophylactic (to prevent or
ameliorate the effects of a future infection by a natural or
"wild" pathogen), or therapeutic
VACCINE CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
5
VACCINE CO3.2
 A vaccine is a biological preparation that provides active acquired immunity to
a particular infectious disease.
 A vaccine typically contains an agent that resembles a disease-causing
microorganism and is often made from weakened or killed forms of the
microbe, its toxins, or one of its surface proteins.
 The agent stimulates the body's immune system to recognize the agent as a
threat, destroy it, and to further recognize and destroy any of the
microorganisms associated with that agent that it may encounter in the future.
 Vaccines can be prophylactic (to prevent or ameliorate the effects of a future
infection by a natural or "wild" pathogen), or therapeutic (e.g., vaccines
against cancer, which are being investigated)
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
6
VACCINE CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
7
VACCINE TYPES CO3.2
 Types
• Inactivated
• Attenuated
• Toxoid
• Subunit
• Conjugate
• Experimental
• Valence
• Heterotypic
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
8
GENERATION OF VACCINES CO3.2
• First generation or traditional vaccines
-live or fixed whole pathogens
• Second generation vaccines
-the native protein antigens purified from the pathogen.
• Third-generation vaccines
-DNA plasmids capable of expressing the sequence of the most important
pathogen protein antigens in the host.
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
9
GENERATION OF VACCINES CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
10
GENERATION OF VACCINES CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
11
HOW VACCINE WORKS? CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
12
HOW VACCINE WORKS? CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
13
VACCINE PREPRATION CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
14
VACCINE PREPRATION CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
15
HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
Follow anyone of these approach:
• Inactivated
• Attenuated
• Toxoid
• Subunit
• Conjugate
• Experimental
• Valence
• Heterotypic
• First generation or traditional vaccines: live or fixed whole pathogens
• Second generation vaccines: native protein antigens purified from the
pathogen.
• Third-generation vaccines : DNA plasmids capable of expressing the
sequence of the most important pathogen protein antigens in the host.
Or
HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
17
HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
18
STORAGE CONDITIONS FOR VACCINES CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3
19
DIFFERENCE BETWEEN VACCINE AND DRUGS CO3.2
20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 2
0
DIFFERENCE BETWEEN VACCINE AND DRUGS CO3.2

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Vaccines

  • 1. General method of the preparation of Bacterial Infections, Toxoids, Viral vaccine, Antitoxins, Serum-immune blood derivatives and other products relative to immunity. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-1 1 CO3.1 Noida Institute of Engineering and Technology (Pharmacy Institute) Greater Noida Abhijit Debnath Asst. Professor NIET, Pharmacy Institute Unit: 3 Subject Name: Biotechnology (BP605T) Course Details (B. Pharm 6th Sem)
  • 2. General Method of the Preparation of 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-1 2  Bacterial infections,  Toxoids,  Viral vaccine,  Antitoxins,  Serum-immune blood derivatives and other products relative to immunity. CO1.1 Noida Institute of Engineering and Technology (Pharmacy Institute) Greater Noida
  • 3. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 3  A vaccine is a biological preparation that provides active acquired immunity to a particular infectious disease.  A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins. VACCINE CO3.2
  • 4. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 4  The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future. Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic VACCINE CO3.2
  • 5. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 5 VACCINE CO3.2  A vaccine is a biological preparation that provides active acquired immunity to a particular infectious disease.  A vaccine typically contains an agent that resembles a disease-causing microorganism and is often made from weakened or killed forms of the microbe, its toxins, or one of its surface proteins.  The agent stimulates the body's immune system to recognize the agent as a threat, destroy it, and to further recognize and destroy any of the microorganisms associated with that agent that it may encounter in the future.  Vaccines can be prophylactic (to prevent or ameliorate the effects of a future infection by a natural or "wild" pathogen), or therapeutic (e.g., vaccines against cancer, which are being investigated)
  • 6. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 6 VACCINE CO3.2
  • 7. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 7 VACCINE TYPES CO3.2  Types • Inactivated • Attenuated • Toxoid • Subunit • Conjugate • Experimental • Valence • Heterotypic
  • 8. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 8 GENERATION OF VACCINES CO3.2 • First generation or traditional vaccines -live or fixed whole pathogens • Second generation vaccines -the native protein antigens purified from the pathogen. • Third-generation vaccines -DNA plasmids capable of expressing the sequence of the most important pathogen protein antigens in the host.
  • 9. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 9 GENERATION OF VACCINES CO3.2
  • 10. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 10 GENERATION OF VACCINES CO3.2
  • 11. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 11 HOW VACCINE WORKS? CO3.2
  • 12. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 12 HOW VACCINE WORKS? CO3.2
  • 13. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 13 VACCINE PREPRATION CO3.2
  • 14. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 14 VACCINE PREPRATION CO3.2
  • 15. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 15 HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
  • 16. Follow anyone of these approach: • Inactivated • Attenuated • Toxoid • Subunit • Conjugate • Experimental • Valence • Heterotypic • First generation or traditional vaccines: live or fixed whole pathogens • Second generation vaccines: native protein antigens purified from the pathogen. • Third-generation vaccines : DNA plasmids capable of expressing the sequence of the most important pathogen protein antigens in the host. Or HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
  • 17. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 17 HOW TO DEVELOP NEW VACCINE FOR COVID-19? CO3.2
  • 18. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 18 STORAGE CONDITIONS FOR VACCINES CO3.2
  • 19. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 19 DIFFERENCE BETWEEN VACCINE AND DRUGS CO3.2
  • 20. 20 July 2021 Abhijit Debnath BP605T and Biotech Unit-3 2 0 DIFFERENCE BETWEEN VACCINE AND DRUGS CO3.2