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Targeting, minimising and measuring
antibiotic use| What is Possible?
Stuart Wilkinson|
Feedworks Pty Ltd
Challenges – consumers/markets/legislation
3
• Increasing compliance and consumer awareness placing
pressure on in-feed medications
• TRUST? – Social Licence
Global Trends
4
Global trends
• Prohibition of antibiotic growth promotants
• Sweden (1986), Denmark (2000), rest of Europe (2006), 75% of the 180 OIE member
nations (2015)
• Decoupling antibiotic prescriptions and sales from veterinarians
• Or price control / margin limits
• Decoupling examples – Spain, Portugal, Sweden, Norway
• No sales margin – Denmark – veterinarian turnover offset by higher number of farm
visits
5
Global trends – Premixes and antibiotics
6
20% reduction in exposure to antibiotics 2011-15
1st step to reducing antibiotic use is to remove from premixes
Global trends
• ZnO
• Medical use of ZnO is being phased out
• Antimicrobial resistance concerns
• Environmental concerns
• Opportunity for alternative strategies
• low dose, highly specific Zinc Oxide like HiZox.
7
Antibiotic Monitoring Systems
8
Antibiotic Monitoring
• VETSTAT (Denmark)
• Since 2000
• Medicine prescriptions recorded centrally
• Vet prescriptions
• Pharmacies
• Feed mills
• All vet prescriptions recorded < 30 days
• Warning to farms (Yellow card) based on antibiotic consumption
• 9 months to improve
9
Australian Perspective 2005-2010
• 98% of antimicrobials sold for animals were
used in food animals
• 43% sold for therapeutic/prophylactic reasons
10
Industry %
Poultry 49
Pigs 36
Cattle and Sheep 15
APVMA (2014)
2005-2010
• Key findings
• Sales data did not indicate a significant change in the volume (MT) of active
ingredients sold
11
APVMA (2014)
Purpose 2005-06 2006-07 2007-08 2008-09 2009-10
Coccidiostat 336.2 302.9 279.3 258.5 327.1
Growth Promotant 47.2 38.2 38.4 23.8 28.9
Therapeutic 271.6 230.4 262.3 199.1 288.0
Total 655.0 571.5 580.0 481.5 644.0
2005-2010
• Delivery of antimicrobials
12
Industry %
Feed 76.4
Water 18.4
Injectable 4
Intramammary 0.7
Other 0.6
APVMA (2014)
People?
1
3
www.safetyandquality.gov.au www.theconversation.com.au
Challenges to Feed Mill Addition
Feed mill challenges
• Extra diets
• Bin management
• Cross contamination
• Scheduling
• Run time (batch size)
• Slower response time
• Inventory management
• Feed intake may be reduced on farm
– dosing?
• Transport logistics – wrong silo on
farm?
15
Alternatives to Feed Mill Addition
Alternatives to addition at the feed mill
• Injectable
• Water
• Micro-dosing
17
Alternatives to addition at the feed mill
• Micro-dosing
18
Micro-dosing on farm
19
Sample Expected (g/MT) Analysed (g/MT) %
1 4.5 3.4 76
2 4.5 4.1 91
3 4.5 4.2 93
4 4.5 4.4 98
5 4.5 4.1 91
6 4.5 4.8 107
7 4.5 4.4 98
8 4.5 3.7 82
9 4.5 3.4 76
10 4.5 4.1 91
Mean 4.06 90.22
Van Barneveld, (2014)
Variability in consumption and exposure to medications
20
Soraci et al (2014)
• Subordinate pigs ate 22% less feed than dominant pigs
Alternatives to Feed Mill Addition | water
Water administration benefits
• Reduced treatment time periods compared to in-feed (5x)
• Fast/responsive to situation
• Targeted – single weaner room / half sheds
• Flexible dosing and duration of administration
• Water intake generally continues in response to hyperthermia or
dehydration
22
Water administration considerations
• Plumbing
• Type of pump
• Solubility
• Dosing rate
• Water consumption
• Volume
• Pattern
23
Water administration considerations
• Precision at low water flow, pressure changes
• Electric pumps require water meters which vary in accuracy (flow
dependent) and longevity (water quality)
• High water flow with high dose % will withstand peak water consumption
24
The future?
25
The future?
26
Greater accountability and traceability
• Increased delivery via drinking water
• Vaccinations
• QR / Barcode recognition of treatment
• Acidification
• Automatic sanitation post depop.
• Water intake
• Report generated detailing treatment / volume / time / batch etc.
27
Thank you
28
Questions?

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3. Friday Monogastric Sessions dr stuart wilkinson feedworks - targeting, minimising and measuring ab use through water and new mirco dosing feeding tech

  • 1. Targeting, minimising and measuring antibiotic use| What is Possible? Stuart Wilkinson| Feedworks Pty Ltd
  • 2. Challenges – consumers/markets/legislation 3 • Increasing compliance and consumer awareness placing pressure on in-feed medications • TRUST? – Social Licence
  • 4. Global trends • Prohibition of antibiotic growth promotants • Sweden (1986), Denmark (2000), rest of Europe (2006), 75% of the 180 OIE member nations (2015) • Decoupling antibiotic prescriptions and sales from veterinarians • Or price control / margin limits • Decoupling examples – Spain, Portugal, Sweden, Norway • No sales margin – Denmark – veterinarian turnover offset by higher number of farm visits 5
  • 5. Global trends – Premixes and antibiotics 6 20% reduction in exposure to antibiotics 2011-15 1st step to reducing antibiotic use is to remove from premixes
  • 6. Global trends • ZnO • Medical use of ZnO is being phased out • Antimicrobial resistance concerns • Environmental concerns • Opportunity for alternative strategies • low dose, highly specific Zinc Oxide like HiZox. 7
  • 8. Antibiotic Monitoring • VETSTAT (Denmark) • Since 2000 • Medicine prescriptions recorded centrally • Vet prescriptions • Pharmacies • Feed mills • All vet prescriptions recorded < 30 days • Warning to farms (Yellow card) based on antibiotic consumption • 9 months to improve 9
  • 9. Australian Perspective 2005-2010 • 98% of antimicrobials sold for animals were used in food animals • 43% sold for therapeutic/prophylactic reasons 10 Industry % Poultry 49 Pigs 36 Cattle and Sheep 15 APVMA (2014)
  • 10. 2005-2010 • Key findings • Sales data did not indicate a significant change in the volume (MT) of active ingredients sold 11 APVMA (2014) Purpose 2005-06 2006-07 2007-08 2008-09 2009-10 Coccidiostat 336.2 302.9 279.3 258.5 327.1 Growth Promotant 47.2 38.2 38.4 23.8 28.9 Therapeutic 271.6 230.4 262.3 199.1 288.0 Total 655.0 571.5 580.0 481.5 644.0
  • 11. 2005-2010 • Delivery of antimicrobials 12 Industry % Feed 76.4 Water 18.4 Injectable 4 Intramammary 0.7 Other 0.6 APVMA (2014)
  • 13. Challenges to Feed Mill Addition
  • 14. Feed mill challenges • Extra diets • Bin management • Cross contamination • Scheduling • Run time (batch size) • Slower response time • Inventory management • Feed intake may be reduced on farm – dosing? • Transport logistics – wrong silo on farm? 15
  • 15. Alternatives to Feed Mill Addition
  • 16. Alternatives to addition at the feed mill • Injectable • Water • Micro-dosing 17
  • 17. Alternatives to addition at the feed mill • Micro-dosing 18
  • 18. Micro-dosing on farm 19 Sample Expected (g/MT) Analysed (g/MT) % 1 4.5 3.4 76 2 4.5 4.1 91 3 4.5 4.2 93 4 4.5 4.4 98 5 4.5 4.1 91 6 4.5 4.8 107 7 4.5 4.4 98 8 4.5 3.7 82 9 4.5 3.4 76 10 4.5 4.1 91 Mean 4.06 90.22 Van Barneveld, (2014)
  • 19. Variability in consumption and exposure to medications 20 Soraci et al (2014) • Subordinate pigs ate 22% less feed than dominant pigs
  • 20. Alternatives to Feed Mill Addition | water
  • 21. Water administration benefits • Reduced treatment time periods compared to in-feed (5x) • Fast/responsive to situation • Targeted – single weaner room / half sheds • Flexible dosing and duration of administration • Water intake generally continues in response to hyperthermia or dehydration 22
  • 22. Water administration considerations • Plumbing • Type of pump • Solubility • Dosing rate • Water consumption • Volume • Pattern 23
  • 23. Water administration considerations • Precision at low water flow, pressure changes • Electric pumps require water meters which vary in accuracy (flow dependent) and longevity (water quality) • High water flow with high dose % will withstand peak water consumption 24
  • 26. Greater accountability and traceability • Increased delivery via drinking water • Vaccinations • QR / Barcode recognition of treatment • Acidification • Automatic sanitation post depop. • Water intake • Report generated detailing treatment / volume / time / batch etc. 27

Editor's Notes

  1. Woolworths bought a 50% stake in a data science and analytics company for $20 million in 2013. That company is now reported to be valued in excess of $400 million, putting Woolworths’ 50% stake at over $200 million – in 5 years.
  2. Woolworths bought a 50% stake in a data science and analytics company for $20 million in 2013. That company is now reported to be valued in excess of $400 million, putting Woolworths’ 50% stake at over $200 million – in 5 years.