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Cell Theory 
1
Cell Theory 
This theory is one of the foundations of 
biology. 
2
Antonie van Leeuwenhoek 
The first man to witness a live cell under a 
microscope was Antonie van Leeuwenhoek, 
who in 1674 described the algae Spirogyra 
and named the moving organisms 
animalcules, meaning “little animals.” 
In 1678, Antoni van Leeuwenhook reported 
that he had observed “little animals” -- 
protozoa -- through a microscope, he also 
called them “little beasties.” 
3
Robert Hooke 
The cell was first discovered by 
Robert Hooke in 1665. He 
observed dead cork (cork comes 
from the bark of a cork oak0 
tree) and named the structures 
he observed “cells” which 
means small room. 
4
Theodor Schwann 
Matthias Jakob Schleiden 
Rudolf Virchow 
In 1839, Schwann and Schleiden suggested 
that cells were the basic unit of life. 
In 1858, Rudolf Virchow concluded that all 
cells come from pre-existing cells, thus 
completing the classical cell theory. 
Theodor Schwann, Matthias Jakob 
Schleiden, and Rudolf Virchow are credited 
with developing cell theory. 
5 
Schwann 
Schleiden 
Virchow
Traditional rules of the 
Cell Theory 
1. All life forms are made 
from one or more cells. 
2. Cells only arise from pre-existing 
cells. 
3. The cell is the smallest 
form of life. 
6
Modern rules of the 
Cell Theory — 1 
1 All known living things are 
made up of cells. All organisms 
are made up of one or more 
cells. 
2 The cell is structural & 
functional unit of all living 
things. 
3 All cells come from pre-existing 
cells by division. (Spontaneous 
Generation does not occur). 
7
Modern rules of the 
Cell Theory — 2 
4 Cells contains hereditary 
information (DNA) which is 
passed from cell to cell during 
cell division. 
5 All cells are basically the same 
in chemical composition. 
6 All energy flow (metabolism & 
biochemistry) of life occurs 
within cells. 
8
Characteristics of Life 
Living? 
Homeostasis 
Organization 
Metabolism 
Growth 
Adaptation 
Response to stimuli 
Reproduce 
Hereditary molecule is DNA 
Viruses 
 Bacteria are living organisms but 
opinions vary on whether viruses are. 
 A virus is an organic structures that 
interacts with living organisms. 
 It does show characteristics of life such 
as having genes, evolving by natural 
selection and reproducing by creating 
multiple copies of themselves through 
self-assembly. 
 But viruses don't have a cellular 
structure or their own metabolism; 
they need a host cell to reproduce. 
9
 Viruses are the smallest and 
simplest life form known. They are 
10 to 100 times smaller than 
bacteria. 
Viruses 
 Viruses must have a living host - like 
a plant or animal - to multiply. 
 Viruses are intracellular organisms 
(they infiltrate the host cell and live 
inside the cell). They change the 
host cell's genetic material from its 
normal function to producing the 
virus itself. 
10
Two basic cell types 
Prokaryotes 
& 
Eukaryotes 
11
Two basic cell types 
Prokaryotes 
& 
Eukaryotes 
12
PPrrookkaarryyootteess 
The lack of a nucleus gives prokaryotes their name.
PPrrookkaarryyootteess 
 The prokaryotes are a 
group of organisms that 
lack a cell nucleus, or any 
other membrane-bound 
organelles. 
 They differ from the 
eukaryotes, which have a 
cell nucleus. 
 Most are unicellular, but 
a few prokaryotes such as 
myxobacteria have 
multicellular stages in 
their life cycles. 
14
Prokaryotes 
 The prokaryotes are divided into 
two domains: the bacteria and the 
archaea. 
 Archaea were recognized as a 
domain of life in 1990. 
 These organisms were originally 
thought to live only in inhospitable 
conditions such as extremes of 
temperature, pH, and radiation 
but have since been found in all 
types of habitats. 
15
Eukaryotes 
The presence of a nucleus gives eukaryotes their name. 
Greek Meaning 
eu good, noble, true 
karyon nut, kernel
Eukaryotic 
A eukaryotic is an 
organism whose 
cells contain 
complex 
structures inside 
the membranes. 
17
 The most important 
membrane-bound structure 
setting eukaryotic cells 
apart from prokaryotic cells 
is the nucleus, or nuclear 
envelope, within which the 
genetic material is carried. 
 Most eukaryotic cells also 
contain other membrane-bound 
organelles such as 
mitochondria, chloroplasts 
and the Golgi apparatus. 
18 
Eukaryotic
Organelles 
Found only in eukaryotic cells 
19
Nucleus 
The “control center,” 
it maintain the integrity 
of these genes and to 
control the activities of 
the cell by regulating 
gene expression. 
20
Nucleolus 
21 
Function: 
Ribosomal RNA (rRNA) 
is transcribed and 
assembled within the 
nucleolus.
Cell Membrane or Plasma Membrane 
22 
Function: 
It separates the interior of 
a cell from the outside 
environment. The cell 
membrane surrounds all 
cells and it is semi-permeable, 
controlling the 
movement of substances in 
and out of cells.
Cell Wall 
23 
 Provides these cells with 
structural support and 
protection, and also acts as a 
filtering mechanism. A major 
function of the cell wall is to 
act as a pressure vessel, 
preventing over-expansion 
when water enters the cell. 
They are found in plants, 
bacteria, fungi, algae, and 
some archaea.
Ribosome 
 Make proteins from amino acids. 
24
Vesicle 
Membrane-enclosed 
sac that stores or 
transports substances 
within a cell. 
25
Rough Endoplasmic Reticulum (RER) 
Ribosome to bind to 
the RER and pass the 
new protein through 
the ER membrane. 
26
Smooth Endoplasmic Reticulum (SER) 
 Several metabolic processes, 
including synthesis of lipids and 
steroids, metabolism of 
carbohydrates, regulation of calcium 
concentration, drug detoxification, 
attachment of receptors on cell 
membrane proteins, and steroid 
metabolism. 
27
Golgi apparatus 
Processes and packages 
macromolecules, such as 
proteins and lipids, after their 
synthesis and before they 
make their way to their 
destination; it is particularly 
important in the processing of 
proteins for secretion 
28
Cytoskeleton 
 It is a dynamic structure that 
maintains cell shape, protects the 
cell, enables cellular motion (using 
structures such as flagella, cilia and 
lamellipodia), and plays important 
roles in both intracellular transport 
(the movement of vesicles and 
organelles, for example) and cellular 
division. 
29
Mitochondria 
 Generate most of the cell’s supply of 
adenosine triphosphate (ATP), used 
as a source of chemical energy. In 
addition to supplying cellular 
energy, they are involved in a range 
of other processes, such as signaling, 
cellular differentiation, cell death, as 
well as the control of the cell cycle 
and cell growth. 
30
Vacuole 
 The function and importance of vacuoles varies greatly 
according to the type of cell in which they are present, 
having much greater prominence in the cells of plants, fungi 
and certain protists than those of animals and bacteria. In 
general, the functions of the vacuole include: 
 Isolating materials that might be harmful or a threat to 
the cell 
 Containing waste products 
 Maintaining internal hydrostatic pressure or turgor 
within the cell 
 Maintaining an acidic internal pH 
 Containing small molecules 
 Exporting unwanted substances from the cell 
 Allows plants to support structures such as leaves and 
flowers due to the pressure of the central vacuole 
31
Cytoplasm 
 Are filled with liquid that is kept separate 
from the rest of the cytoplasm by 
biological membranes. The cytoplasm is 
the site where most cellular activities 
occur, such as many metabolic pathways 
like glycolysis, and processes such as cell 
division. 
32
Lysosome 
Lysosomes digest 
excess or worn-out 
organelles, food 
particles, and 
engulfed viruses or 
bacteria. 
33
Centrioles within Centrosome 
 These are involved in the organization of 
the mitotic spindle and in the completion 
of cytokinesis (the process in which the 
cytoplasm of a single eukaryotic cell is 
divided to form two daughter cells). 
34
Chloroplasts 
Chloroplasts capture light 
energy to conserve free 
energy in the form of ATP 
and reduce NADP to 
NADPH through a complex 
set of processes called 
photosynthesis. 
35
Organelles 
PPllaannttss 
Cell Membrane 
Cell walls 
Chloroplasts 
Vacuoles 
 Lysosomes 
Golgi Bodies 
Mitochondria 
Endoplasmic Reticulum 
(ER) 
Ribosomes 
AAnniimmaallss 
Cell Membrane 
Centrioles (used in cellular 
reproduction) 
Vacuoles 
Lysosomes 
Golgi Bodies 
Mitochondria 
Endoplasmic Reticulum 
(ER) 
Ribosomes 
36
Cell Theory Rap 
Listen close to the story I tell. 
It’s the rapping story of the living 
cell. 
It’s a happy tune that’s sort of 
cheery. 
About a real tough topic called the 
cell theory. 
All animals, plants, and protists 
too, 
Are made of cells with different 
jobs to do. 
They’re the basic units of all 
organisms, 
And I hope by now you got the 
rhythm. 
37
It all started with one dude named 
Hooke. 
Who at some cork cells took a 
look. 
He used a scope and took his time. 
‘Cause a cell is small and thinner 
than a dime. 
Say 1, 2, 3, 4, 
Are you ready to learn some 
more? 
The animal cell has many parts, 
And you must know each one by 
heart. 
38
Like the farmer man in the dell. 
The nucleus controls the cell. 
its gives the orders -- kind of like a 
brain. 
And it’s protected by a nuclear 
membrane. 
Around the cell, you’ll find another 
“skin,” 
The cellular membrane holds the 
whole cell in 
But its job isn’t simple there’s no 
doubt, 
It lets some particles go in and out. 
39
Now please don’t lose your science 
enthusiasm, 
Listen to the story of the 
cytoplasm. 
All around the cell this thick fluid 
does go, 
But in the nucleus it will not flow. 
And don’t forget those ribosomes - 
This is where proteins come from. 
These protein factories are so 
small, you’ll agree, 
You need an electron microscope 
to see. 
40
Just when you thought you 
weren’t having any fun, 
Along comes teh endoplasmic 
reticulum. 
These tubelike structures serve as 
a track, 
To carry stuff to the membrane 
and back. 
Now have you ever seen any 
doughnuts without holes? 
In a cell, they’re called vacuoles. 
They’re filled with stuff like H2O 
And they carry food so the cell can 
grow. 
41
Las of all, but not the very least, 
Mitochondria - mighty cellular 
beasts, 
Since they turn sugars into energy 
so well, 
We call them the powerhouse of 
the cell. 
Now my friend, you know it well, 
The unforgettable story of the 
living cell. 
“Science World” 
10-5-90 
42

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Cell Theory: The Foundation of Biology in 40 Characters

  • 2. Cell Theory This theory is one of the foundations of biology. 2
  • 3. Antonie van Leeuwenhoek The first man to witness a live cell under a microscope was Antonie van Leeuwenhoek, who in 1674 described the algae Spirogyra and named the moving organisms animalcules, meaning “little animals.” In 1678, Antoni van Leeuwenhook reported that he had observed “little animals” -- protozoa -- through a microscope, he also called them “little beasties.” 3
  • 4. Robert Hooke The cell was first discovered by Robert Hooke in 1665. He observed dead cork (cork comes from the bark of a cork oak0 tree) and named the structures he observed “cells” which means small room. 4
  • 5. Theodor Schwann Matthias Jakob Schleiden Rudolf Virchow In 1839, Schwann and Schleiden suggested that cells were the basic unit of life. In 1858, Rudolf Virchow concluded that all cells come from pre-existing cells, thus completing the classical cell theory. Theodor Schwann, Matthias Jakob Schleiden, and Rudolf Virchow are credited with developing cell theory. 5 Schwann Schleiden Virchow
  • 6. Traditional rules of the Cell Theory 1. All life forms are made from one or more cells. 2. Cells only arise from pre-existing cells. 3. The cell is the smallest form of life. 6
  • 7. Modern rules of the Cell Theory — 1 1 All known living things are made up of cells. All organisms are made up of one or more cells. 2 The cell is structural & functional unit of all living things. 3 All cells come from pre-existing cells by division. (Spontaneous Generation does not occur). 7
  • 8. Modern rules of the Cell Theory — 2 4 Cells contains hereditary information (DNA) which is passed from cell to cell during cell division. 5 All cells are basically the same in chemical composition. 6 All energy flow (metabolism & biochemistry) of life occurs within cells. 8
  • 9. Characteristics of Life Living? Homeostasis Organization Metabolism Growth Adaptation Response to stimuli Reproduce Hereditary molecule is DNA Viruses  Bacteria are living organisms but opinions vary on whether viruses are.  A virus is an organic structures that interacts with living organisms.  It does show characteristics of life such as having genes, evolving by natural selection and reproducing by creating multiple copies of themselves through self-assembly.  But viruses don't have a cellular structure or their own metabolism; they need a host cell to reproduce. 9
  • 10.  Viruses are the smallest and simplest life form known. They are 10 to 100 times smaller than bacteria. Viruses  Viruses must have a living host - like a plant or animal - to multiply.  Viruses are intracellular organisms (they infiltrate the host cell and live inside the cell). They change the host cell's genetic material from its normal function to producing the virus itself. 10
  • 11. Two basic cell types Prokaryotes & Eukaryotes 11
  • 12. Two basic cell types Prokaryotes & Eukaryotes 12
  • 13. PPrrookkaarryyootteess The lack of a nucleus gives prokaryotes their name.
  • 14. PPrrookkaarryyootteess  The prokaryotes are a group of organisms that lack a cell nucleus, or any other membrane-bound organelles.  They differ from the eukaryotes, which have a cell nucleus.  Most are unicellular, but a few prokaryotes such as myxobacteria have multicellular stages in their life cycles. 14
  • 15. Prokaryotes  The prokaryotes are divided into two domains: the bacteria and the archaea.  Archaea were recognized as a domain of life in 1990.  These organisms were originally thought to live only in inhospitable conditions such as extremes of temperature, pH, and radiation but have since been found in all types of habitats. 15
  • 16. Eukaryotes The presence of a nucleus gives eukaryotes their name. Greek Meaning eu good, noble, true karyon nut, kernel
  • 17. Eukaryotic A eukaryotic is an organism whose cells contain complex structures inside the membranes. 17
  • 18.  The most important membrane-bound structure setting eukaryotic cells apart from prokaryotic cells is the nucleus, or nuclear envelope, within which the genetic material is carried.  Most eukaryotic cells also contain other membrane-bound organelles such as mitochondria, chloroplasts and the Golgi apparatus. 18 Eukaryotic
  • 19. Organelles Found only in eukaryotic cells 19
  • 20. Nucleus The “control center,” it maintain the integrity of these genes and to control the activities of the cell by regulating gene expression. 20
  • 21. Nucleolus 21 Function: Ribosomal RNA (rRNA) is transcribed and assembled within the nucleolus.
  • 22. Cell Membrane or Plasma Membrane 22 Function: It separates the interior of a cell from the outside environment. The cell membrane surrounds all cells and it is semi-permeable, controlling the movement of substances in and out of cells.
  • 23. Cell Wall 23  Provides these cells with structural support and protection, and also acts as a filtering mechanism. A major function of the cell wall is to act as a pressure vessel, preventing over-expansion when water enters the cell. They are found in plants, bacteria, fungi, algae, and some archaea.
  • 24. Ribosome  Make proteins from amino acids. 24
  • 25. Vesicle Membrane-enclosed sac that stores or transports substances within a cell. 25
  • 26. Rough Endoplasmic Reticulum (RER) Ribosome to bind to the RER and pass the new protein through the ER membrane. 26
  • 27. Smooth Endoplasmic Reticulum (SER)  Several metabolic processes, including synthesis of lipids and steroids, metabolism of carbohydrates, regulation of calcium concentration, drug detoxification, attachment of receptors on cell membrane proteins, and steroid metabolism. 27
  • 28. Golgi apparatus Processes and packages macromolecules, such as proteins and lipids, after their synthesis and before they make their way to their destination; it is particularly important in the processing of proteins for secretion 28
  • 29. Cytoskeleton  It is a dynamic structure that maintains cell shape, protects the cell, enables cellular motion (using structures such as flagella, cilia and lamellipodia), and plays important roles in both intracellular transport (the movement of vesicles and organelles, for example) and cellular division. 29
  • 30. Mitochondria  Generate most of the cell’s supply of adenosine triphosphate (ATP), used as a source of chemical energy. In addition to supplying cellular energy, they are involved in a range of other processes, such as signaling, cellular differentiation, cell death, as well as the control of the cell cycle and cell growth. 30
  • 31. Vacuole  The function and importance of vacuoles varies greatly according to the type of cell in which they are present, having much greater prominence in the cells of plants, fungi and certain protists than those of animals and bacteria. In general, the functions of the vacuole include:  Isolating materials that might be harmful or a threat to the cell  Containing waste products  Maintaining internal hydrostatic pressure or turgor within the cell  Maintaining an acidic internal pH  Containing small molecules  Exporting unwanted substances from the cell  Allows plants to support structures such as leaves and flowers due to the pressure of the central vacuole 31
  • 32. Cytoplasm  Are filled with liquid that is kept separate from the rest of the cytoplasm by biological membranes. The cytoplasm is the site where most cellular activities occur, such as many metabolic pathways like glycolysis, and processes such as cell division. 32
  • 33. Lysosome Lysosomes digest excess or worn-out organelles, food particles, and engulfed viruses or bacteria. 33
  • 34. Centrioles within Centrosome  These are involved in the organization of the mitotic spindle and in the completion of cytokinesis (the process in which the cytoplasm of a single eukaryotic cell is divided to form two daughter cells). 34
  • 35. Chloroplasts Chloroplasts capture light energy to conserve free energy in the form of ATP and reduce NADP to NADPH through a complex set of processes called photosynthesis. 35
  • 36. Organelles PPllaannttss Cell Membrane Cell walls Chloroplasts Vacuoles  Lysosomes Golgi Bodies Mitochondria Endoplasmic Reticulum (ER) Ribosomes AAnniimmaallss Cell Membrane Centrioles (used in cellular reproduction) Vacuoles Lysosomes Golgi Bodies Mitochondria Endoplasmic Reticulum (ER) Ribosomes 36
  • 37. Cell Theory Rap Listen close to the story I tell. It’s the rapping story of the living cell. It’s a happy tune that’s sort of cheery. About a real tough topic called the cell theory. All animals, plants, and protists too, Are made of cells with different jobs to do. They’re the basic units of all organisms, And I hope by now you got the rhythm. 37
  • 38. It all started with one dude named Hooke. Who at some cork cells took a look. He used a scope and took his time. ‘Cause a cell is small and thinner than a dime. Say 1, 2, 3, 4, Are you ready to learn some more? The animal cell has many parts, And you must know each one by heart. 38
  • 39. Like the farmer man in the dell. The nucleus controls the cell. its gives the orders -- kind of like a brain. And it’s protected by a nuclear membrane. Around the cell, you’ll find another “skin,” The cellular membrane holds the whole cell in But its job isn’t simple there’s no doubt, It lets some particles go in and out. 39
  • 40. Now please don’t lose your science enthusiasm, Listen to the story of the cytoplasm. All around the cell this thick fluid does go, But in the nucleus it will not flow. And don’t forget those ribosomes - This is where proteins come from. These protein factories are so small, you’ll agree, You need an electron microscope to see. 40
  • 41. Just when you thought you weren’t having any fun, Along comes teh endoplasmic reticulum. These tubelike structures serve as a track, To carry stuff to the membrane and back. Now have you ever seen any doughnuts without holes? In a cell, they’re called vacuoles. They’re filled with stuff like H2O And they carry food so the cell can grow. 41
  • 42. Las of all, but not the very least, Mitochondria - mighty cellular beasts, Since they turn sugars into energy so well, We call them the powerhouse of the cell. Now my friend, you know it well, The unforgettable story of the living cell. “Science World” 10-5-90 42