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Mechanical Ventilation
•Why do we ventilate?
    – Inadequate Ventilation (C02 too high)
    – Inadequate Oxygenation (02 too low)
    – Patients intubated for Airway protection
•How do we ventilate?
    – Invasively
        • Via Endotracheal / Tracheostomy tube
    – Non-invasively
        • Via mask




Covidien |   | Confidential
Indications for Mechanical Ventilation


•Elective
     – To allow for sedation and paralysis during major
       surgery
•Therapeutic
     – Inadequate Alveolar Ventilation
     – Refractory Hypoxemia
     – Airway protection (indication for intubation)



Covidien |   | Confidential
Inadequate Alveolar Ventilation
•Apnea
•Respiratory Failure
•Impending Respiratory Failure




Covidien |   | Confidential
Inadequate Alveolar Ventilation
     – Resuscitation
     – Neuromuscular Disorders
        • Poliomyelitis
        • Guillian-Barre
        • Phrenic Nerve Paralysis
     – CNS disorders
        • Cerebral trauma
        • Spinal cord injury
        • Narcotic / barbiturate poisoning




Covidien |   | Confidential
Inadequate Alveolar Ventilation
     – Chest Wall Diseases
     – Excessive Work of Breathing
     – Acute Airway Obstruction
             • COPD exacerbation
             • Severe Asthma
             • Excessive Secretions
     – Intra-thorax
             • Pleural disease



Covidien |   | Confidential
Refractory Hypoxemia
     – Pneumonia
     – Atelectasis
     – Pulmonary Edema
     – ARDS




Covidien |   | Confidential
Airway protection
•Inadequate cough / gag
•Tracheal obstruction / trauma
•Severe Allergic Reaction




Covidien |   | Confidential
Signs of Respiratory Failure
    •Respiratory Rate         >35/minute
    •Tidal Volume             <2mL/kg
    •Minute Ventilation       <5L/minute or > 12L/minute
    •Vital Capacity           <10mL/kg (N=65/75)
    •Negative Inspiratory     <20cmH20
    •Force
    •Vd / Vt                  0.60 (N=0.3)
    •PaC02                    >10 above baseline
    •pH                       <7.30 with increased C02
    •HR and BP                > 20% baseline




Covidien |   | Confidential
Signs of Respiratory Failure
•Subjective signs
     – Increasing breathlessness
     – Fatigue
     – Change in level of consciousness
     – Use of accessory muscles
     – Diaphoresis




Covidien |   | Confidential
Ventilation system
                                        PMOUTH
                                        .
                                        VPATIENT
                            Patient Y
                                                   CI, RI
      P
     . e
     VE
                   CE, RE                           Humidifier


                                             CH
              Return To
              Ventilator
         We measure pressure and flow at
         the inspiratory and expiratory
         sides of the circuit, but we want
         pressure and flow at the Y and            Pi   From
                                                   .
Covidien lungConfidential
          | | volume
                                                   VI   Ventilator
Modes of Ventilation
•Assist / Control
     – All breaths are machine delivered breaths
     – Can be machine or patient initiated
•Mixed Modes
     – Combination of machine breaths and patient’s
       own spontaneous breaths
•Spontaneous
     – All breaths initiated by the patient

Covidien |   | Confidential
Classification of Breath Types
    •What are we controlling or targeting?
        – Volume
        – Pressure
        – % Work of Breathing
    •Why does the breath stop?
        – A set volume has been delivered (vent decides)
        – A set pressure has been reached (vent decides)
        – A set period of time has elapsed (vent decides)
        – The breath is at its natural completion (flow into the patient has stopped)
           (patient can decide)




Covidien |   | Confidential

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Mechanical ventilation

  • 1. Mechanical Ventilation •Why do we ventilate? – Inadequate Ventilation (C02 too high) – Inadequate Oxygenation (02 too low) – Patients intubated for Airway protection •How do we ventilate? – Invasively • Via Endotracheal / Tracheostomy tube – Non-invasively • Via mask Covidien | | Confidential
  • 2. Indications for Mechanical Ventilation •Elective – To allow for sedation and paralysis during major surgery •Therapeutic – Inadequate Alveolar Ventilation – Refractory Hypoxemia – Airway protection (indication for intubation) Covidien | | Confidential
  • 3. Inadequate Alveolar Ventilation •Apnea •Respiratory Failure •Impending Respiratory Failure Covidien | | Confidential
  • 4. Inadequate Alveolar Ventilation – Resuscitation – Neuromuscular Disorders • Poliomyelitis • Guillian-Barre • Phrenic Nerve Paralysis – CNS disorders • Cerebral trauma • Spinal cord injury • Narcotic / barbiturate poisoning Covidien | | Confidential
  • 5. Inadequate Alveolar Ventilation – Chest Wall Diseases – Excessive Work of Breathing – Acute Airway Obstruction • COPD exacerbation • Severe Asthma • Excessive Secretions – Intra-thorax • Pleural disease Covidien | | Confidential
  • 6. Refractory Hypoxemia – Pneumonia – Atelectasis – Pulmonary Edema – ARDS Covidien | | Confidential
  • 7. Airway protection •Inadequate cough / gag •Tracheal obstruction / trauma •Severe Allergic Reaction Covidien | | Confidential
  • 8. Signs of Respiratory Failure •Respiratory Rate >35/minute •Tidal Volume <2mL/kg •Minute Ventilation <5L/minute or > 12L/minute •Vital Capacity <10mL/kg (N=65/75) •Negative Inspiratory <20cmH20 •Force •Vd / Vt 0.60 (N=0.3) •PaC02 >10 above baseline •pH <7.30 with increased C02 •HR and BP > 20% baseline Covidien | | Confidential
  • 9. Signs of Respiratory Failure •Subjective signs – Increasing breathlessness – Fatigue – Change in level of consciousness – Use of accessory muscles – Diaphoresis Covidien | | Confidential
  • 10. Ventilation system PMOUTH . VPATIENT Patient Y CI, RI P . e VE CE, RE Humidifier CH Return To Ventilator We measure pressure and flow at the inspiratory and expiratory sides of the circuit, but we want pressure and flow at the Y and Pi From . Covidien lungConfidential | | volume VI Ventilator
  • 11. Modes of Ventilation •Assist / Control – All breaths are machine delivered breaths – Can be machine or patient initiated •Mixed Modes – Combination of machine breaths and patient’s own spontaneous breaths •Spontaneous – All breaths initiated by the patient Covidien | | Confidential
  • 12. Classification of Breath Types •What are we controlling or targeting? – Volume – Pressure – % Work of Breathing •Why does the breath stop? – A set volume has been delivered (vent decides) – A set pressure has been reached (vent decides) – A set period of time has elapsed (vent decides) – The breath is at its natural completion (flow into the patient has stopped) (patient can decide) Covidien | | Confidential