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Care and Maintenance of
  Soft Contact Lenses



    Vishakh G Nair
   M.Optom,FIACLE
Outline of the presentation
• Why care for contact lenses?
• Deposits & Types
• Lens care regimen
    • Components of lens care solution
    • Functions
    • Steps in lens care and maintenance
    • Types of disinfectants
    • Do-s & Don’t-s
Outline of the presentation
• Why care for contact lenses?
• Deposits & Types
• Lens care regimen
    • Components of lens care solution
    • Functions
    • Steps in lens care and maintenance
    • Types of disinfectants
    • Do-s & Don’t-s
Purpose of Care and Maintenance
• Clean lenses:
  –   To prevent/minimize deposits
  –   To maintain hydration and wettability
  –   To provide comfort and clear vision
  –   To prevent or reduce the risk of ocular
      infection/inflammation
Purpose of Care & Maintenance
• Failure to prescribe proper
  lens care regimen

• Failure of compliance
                                           Failure of
      Reduced comfort
      Reduced vision
      Increased risk of contamination 
       complications/ infections
                                            CL wear
      Dissatisfied patient
Outline of the presentation
• Why care for contact lenses?
• Deposits & Types
• Lens care regimen
    • Components of lens care solution
    • Functions
    • Steps in lens care and maintenance
    • Types of disinfectants
    • Do-s & Don’t-s
Deposits & Types
• “… Any lens surface coating or matrix
  formation which is not flushed or rinsed from
  a lens by tears during blinking”

Types of deposits:
• External
  – eye make-up, air pollutants , etc.
• Internal
  – tear components - protein, lipid, mucin, etc.
Contact Lens Deposits

• How do deposits form on contact lens
  surface?
  – Interaction between lens and content of tears
  – Evaporation of tears leaves residue on lens
  – Lens chemistry attracts tear film constituents
    (proteins, lipids, mucin, calcium)
Protein Deposits
How do protein deposits get denatured?
                                Environmental
                                Factors:
                                • Heat
                                • Drying
                                • Oxidation
                                • UV light

Native Protein                                  Denatured Protein
•   Transparent                                 •   Translucent/opaque
•   Natural part of tears                       •   Strongly binds to lens
•   Beneficial to eyes                              surface
    (anti-microbial activity)                   •   Harmful to eyes
Lipid Deposits
Jelly Bumps
Other Deposits




Calcium Deposit          Fungal Contamination



                               Rust Spots
Deposit Complications
• Reduced visual acuity
• Lens dryness - proteins repel water & the lens may dry
  up more easily
• Irritation and reduced comfort  shortened wear time
• Cause allergic response (e.g. GPC)
• Micro-organism’s attachment to deposits may cause eye
  infection
Non-wetting SCL surface
FDA Classification of Lens Materials


Group   Water Content     Charge

 I       Low (< 50%)     Non Ionic
 II      High (> 50%)    Non Ionic

 III        Low           Ionic
 IV         High          Ionic
Outline of the presentation
• Why care for contact lenses?
• Deposits & Types
• Lens care regimen
    • Components of lens care solution
    • Functions
    • Steps in lens care and maintenance
    • Types of disinfectants
    • Do-s & Don’t-s
Components of Care and Maintenance
½ Daily cleaner
½ Rinsing solution
½ Disinfecting solution
½ Protein removers
½ Lubricating/
rewetting
  solution
½ Lens storage case
Compliance Vs Non- Compliance
Simple system and Instruction
               - Better compliance
               - Easy and convenient
Complicated System
                - Confusion
                - Non-compliance
                - Lens wear complications
Essential Steps of Care & Maintenance

½ Cleaning
½ Rinsing
½ Disinfecting
½ Extra Steps - Protein Removal
                 - Lubricating / Re-wetting
Daily Cleaning and / or Rinsing removes
majority of Micro-organisms
Essential Steps of Care & Maintenance

½ Cleaning
½ Rinsing
½ Disinfecting
½ Extra Steps - Protein Removal
                 - Lubricating / Re-wetting
Daily Cleaner - Functions

To Remove
½ Loosely bound foreign matter
     - Cell debris
     - Mucus, lipid, protein
     - Cosmetic or other surface contamination
½ Majority of micro-organisms
Daily Cleaner Composition

•   Surfactants
•   Buffers
•   Osmolality adjusting agents
•   Preservatives
•   Water
Surfactant Cleaners - Functions
• Remove deposits by:
  – interacting with deposits
  – displacing deposits from lens surface
• Emulsify oils and lipids
• Destroy/dislodge micro-organisms
• Prepare lens for rinsing and disinfection
Daily Cleaner Procedures
½ Wash hands
½ Place lens in the palm of the hand
½ Place 2-3 drops of cleaner on each lens surface
½ Rub with fore-finger for about 10-15 sec per side
  using to and fro and circular action
½ Rolling the fore-finger in both directions
½ Clean lens periphery
½ Rinse well
Daily Lens Care Procedures




Wash hands           Either Rub + Rinse




 Disinfect              Or Rinse Only
Hand washing

      - Reduce bio-burden

      - With water-based soaps

      - Often forgotten step
Rubbing the lens
        • 10-15 sec on each side

        • To and fro action

        • Removal of
          environmental & protein
          deposits

        • Reduces risks of
          infections
Consumer’s perception of No Rub

• Simply put the lenses into lens case after
  removal
• No digital cleaning, No rinsing
• Simple, carefree, convenient lens care
• Reduced usage of lens care solution
Essential Steps of Care & Maintenance

½ Cleaning
½ Rinsing
½ Disinfecting
½ Extra Steps - Protein Removal
                 - Lubricating / Re-wetting
Rinsing

  • Wash off loosened debris

  • Decrease risk of deposit
    related problems
Essential Steps of Care & Maintenance

½ Cleaning
½ Rinsing
½ Disinfecting
½ Extra Steps - Protein Removal
                 - Lubricating / Re-wetting
Disinfecting System
½ Kill or Deactivate potentially pathogenic
organisms including

        -Bacteria
        -Fungi
        -Viruses
        -Amoebas

½ Maintain lens hydration  stable parameters
Disinfection
      • Store the lenses for
        at least 4 hours in
        FRESH solution

      • Decreases the risk
        of infections
Types of Disinfection

Heat
       - Thermal Unit
       - Microwave
Chemical
       - Oxidative
             - Hydrogen peroxide
             - Chlorine
       - Cold Chemicals
             - Various disinfectants
Thermal Disinfection
• Original form of disinfection - discontinued in the
  market



• Procedures
   – Clean and rinse lenses
   – Place lenses in fresh saline in lens case
   – Heat to 70° - 80°C for 10-20 minutes
   – After heat cycle, allow lenses to cool before use
Thermal Disinfection
Advantages:
• Short disinfection cycle times
• Highly effective antimicrobial action
• Low risk of toxic or allergic reactions

Disadvantages:
• Incompatible with some lenses, e.g. high water content;
  may cause deformation & discoloration
• Increased protein deposition (cook the protein onto the
  lens) & causes allergic response
• Suitable electrical power for heat units may not always
  be available
Chemical Disinfection
Chemical Disinfection
½ Disinfection achieved by the presence
preservative
     - Thiomersal, Chlorhexidine, Sorbic acid

½ Disinfection depends on the concentration
and type of preservative

½ Preservatives are potential irritants though
rare
Modern Chemical Disinfectants
• Used in Multi-Purpose (All-in-one) Solutions:
• Polyaminopropyl biguanide (PABA, PHMB)
• Quaternary-ammonia (Polyquad) & Aldox

                       Much less incidence of solution
                       sensitivity than older generation of
                       disinfectants. Because the
                       molecules specifically bind to cell
                       membrane of micro-organism rather
                       than human cells.
Bacteria   Human eye
Multipurpose Solutions
Single bottle of solution for cleaning, rinsing,
  disinfection, & removing protein

Advantages:
•   Simple, convenient, easy transport
•   Enhanced safety due to lower toxicity & complications
•   Doesn’t cause protein denaturation
•   Improved compliance

Disadvantages:
• Small incidence of mild sensitivity reactions
Hydrogen Peroxide
 Advantages:
 • Preservative free – theoretically less allergy
 • Effective disinfection

 Disadvantages:
 • Inflexible neutralization time (lens must be fully
   neutralized before use)
 • H2O2 concentration decreased rapidly (3% to 1% in
   <10mins) - decreased anti-microbial efficacy
 • Not suitable for all lens types
 • Potential for irritation on incomplete neutralization
 • Possible recontamination
Choice of Lens Care System
  SCL         Heat   MPS      Hydrogen
                              Peroxide
Low water,                       
 Non-ionic
High water,   Some                *
 Non-ionic
Low water,                       
  Ionic
High water,                      *
   Ionic
                            * Bleaches color
                            in cosmetic CLs
Recommendations

½ Discard solution everyday
½ Rub and Rinse step is essential with
combination solution
½ Keep nozzle closed
½ Narrow openings
½ Clean and rinse well
½ Soak for recommended time
Essential Steps of Care & Maintenance

½ Cleaning
½ Rinsing
½ Disinfecting
½ Extra Steps - Protein Removal
                 - Lubricating / Re-wetting
Protein Removers
½ Effectively remove protein deposits
½ Have no effect on most other deposits
½ React by breaking protein molecules
½ For heavy depositors; conventional lens user
Protein Removal Procedure

½ Use regularly after daily wear and rinsing step
½ Lenses should be soaked in enzyme, dissolve
in solution / saline for 15 min or over night
depending on manufacturer

½ Lenses should be thoroughly rubbed and
rinsed again afterwards
Essential Steps of Care & Maintenance

½ Cleaning
½ Rinsing
½ Disinfecting
½ Extra Steps - Protein Removal
                 - Lubricating / Re-wetting
Rewetting or Lubricating Drops

½ Alleviating signs of dryness and discomfort

½ Flushing irritation particles from eye and CL

½ Rehydrating lens
Care for Lens Cases
½ Scrub with new tooth brush using cleaning
solution weekly
½ Rinse with saline or disinfecting solution
½ Air dry up-side down
½ Replace case regularly
Dos and Don'ts of
CL care and maintenance
Do-s
Always wash your hands
before handling contact
lenses




Check the position
of lenses before
insertion
Cosmetics/Make-up
Put your contact
  lenses in
• after applying hair
  products like
  hairspray

• before applying
  cosmetics,
  especially eye
  makeup.
Instruction for eye makeup
• Insert your lenses before applying
  make up

• Remove your lenses before taking
  your makeup off.
Avoid Harmful or Irritating Fumes
while the Lenses Are on
Do Rinse the Lenses
• Always before inserting the lens and
  after removing it from the eye

• Rinse the lens with contact lenses
  solution suggested by your practitioner
Clean and change the solution
in the lens case Daily




 Keep your contact
 lenses either in your eyes
 or in your lens case
Don’t-s
Do not let hair spray or
other cosmetic aerosols
come in contact with
your lenses.



Avoid Long and Dirty
Nails
Do not Swim with contact lenses
if Yes with swimming goggles only
Don’t sleep with contact lenses
• Remove your lenses
  before going to
  sleep
   Your cornea may not
   get the necessary
   oxygen* while you
   are sleeping.

* Continuous wear lenses or Extended wear lenses with High
Dk can be used upon practitioner’s recommendations
Additional Tips for Hygienic CL Wear

• Do not mix solution types and brands

• Never soak/store lenses in saline or tap water

• Don’t put your solutions and lens case in the toilet or
  refrigerator

• Don’t touch the tip of the any contact lens solution

• Don’t use any topical eye drops when wearing lenses
Dirty lenses can cause
infection / inflammation
Immediate contact with ECP
• If your eyes get red and irritated or if you feel
  any pain remove your lenses and contact
  your eye care practitioner
How to avoid infection?
• Deposits can be avoided by maintaining a
  good lens care regimen
• Cleaning
• Disinfection
• Following the instruction
• Shorter is better – Disposables, small packs
  of solution (120ml or 360ml rather than
  500ml)
Why disposable ?
•   More comfortable
•   Healthy
•   More hygeinic
•   Convenience of spare pair at hand
•   Longer wearing time
•   Contact lenses related infection & complication
    reduces in disposables
How to enhance compliance?
• Educate staff & the patient
- Simple written & verbal instructions
- Reinforce few key points many times
- Practical demonstration/visuals

• Review lens care at every visit
• Keep patients coming back for more
- Compliance packs/offers
- Recall system
- Regular contact through mailers
Summary

Minimized adverse reactions achieved by :
• clean, well fitted lenses
• adequate physiological performance
• appropriate choice of care system
• regular monitoring of patient
• patient compliance

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care and maintenance of soft contact lenses

  • 1. Care and Maintenance of Soft Contact Lenses Vishakh G Nair M.Optom,FIACLE
  • 2. Outline of the presentation • Why care for contact lenses? • Deposits & Types • Lens care regimen • Components of lens care solution • Functions • Steps in lens care and maintenance • Types of disinfectants • Do-s & Don’t-s
  • 3. Outline of the presentation • Why care for contact lenses? • Deposits & Types • Lens care regimen • Components of lens care solution • Functions • Steps in lens care and maintenance • Types of disinfectants • Do-s & Don’t-s
  • 4. Purpose of Care and Maintenance • Clean lenses: – To prevent/minimize deposits – To maintain hydration and wettability – To provide comfort and clear vision – To prevent or reduce the risk of ocular infection/inflammation
  • 5. Purpose of Care & Maintenance • Failure to prescribe proper lens care regimen • Failure of compliance Failure of  Reduced comfort  Reduced vision  Increased risk of contamination  complications/ infections CL wear  Dissatisfied patient
  • 6. Outline of the presentation • Why care for contact lenses? • Deposits & Types • Lens care regimen • Components of lens care solution • Functions • Steps in lens care and maintenance • Types of disinfectants • Do-s & Don’t-s
  • 7. Deposits & Types • “… Any lens surface coating or matrix formation which is not flushed or rinsed from a lens by tears during blinking” Types of deposits: • External – eye make-up, air pollutants , etc. • Internal – tear components - protein, lipid, mucin, etc.
  • 8. Contact Lens Deposits • How do deposits form on contact lens surface? – Interaction between lens and content of tears – Evaporation of tears leaves residue on lens – Lens chemistry attracts tear film constituents (proteins, lipids, mucin, calcium)
  • 10. How do protein deposits get denatured? Environmental Factors: • Heat • Drying • Oxidation • UV light Native Protein Denatured Protein • Transparent • Translucent/opaque • Natural part of tears • Strongly binds to lens • Beneficial to eyes surface (anti-microbial activity) • Harmful to eyes
  • 13. Other Deposits Calcium Deposit Fungal Contamination Rust Spots
  • 14. Deposit Complications • Reduced visual acuity • Lens dryness - proteins repel water & the lens may dry up more easily • Irritation and reduced comfort  shortened wear time • Cause allergic response (e.g. GPC) • Micro-organism’s attachment to deposits may cause eye infection
  • 16. FDA Classification of Lens Materials Group Water Content Charge I Low (< 50%) Non Ionic II High (> 50%) Non Ionic III Low Ionic IV High Ionic
  • 17. Outline of the presentation • Why care for contact lenses? • Deposits & Types • Lens care regimen • Components of lens care solution • Functions • Steps in lens care and maintenance • Types of disinfectants • Do-s & Don’t-s
  • 18. Components of Care and Maintenance ½ Daily cleaner ½ Rinsing solution ½ Disinfecting solution ½ Protein removers ½ Lubricating/ rewetting solution ½ Lens storage case
  • 19. Compliance Vs Non- Compliance Simple system and Instruction - Better compliance - Easy and convenient Complicated System - Confusion - Non-compliance - Lens wear complications
  • 20. Essential Steps of Care & Maintenance ½ Cleaning ½ Rinsing ½ Disinfecting ½ Extra Steps - Protein Removal - Lubricating / Re-wetting
  • 21. Daily Cleaning and / or Rinsing removes majority of Micro-organisms
  • 22. Essential Steps of Care & Maintenance ½ Cleaning ½ Rinsing ½ Disinfecting ½ Extra Steps - Protein Removal - Lubricating / Re-wetting
  • 23. Daily Cleaner - Functions To Remove ½ Loosely bound foreign matter - Cell debris - Mucus, lipid, protein - Cosmetic or other surface contamination ½ Majority of micro-organisms
  • 24. Daily Cleaner Composition • Surfactants • Buffers • Osmolality adjusting agents • Preservatives • Water
  • 25. Surfactant Cleaners - Functions • Remove deposits by: – interacting with deposits – displacing deposits from lens surface • Emulsify oils and lipids • Destroy/dislodge micro-organisms • Prepare lens for rinsing and disinfection
  • 26. Daily Cleaner Procedures ½ Wash hands ½ Place lens in the palm of the hand ½ Place 2-3 drops of cleaner on each lens surface ½ Rub with fore-finger for about 10-15 sec per side using to and fro and circular action ½ Rolling the fore-finger in both directions ½ Clean lens periphery ½ Rinse well
  • 27. Daily Lens Care Procedures Wash hands Either Rub + Rinse Disinfect Or Rinse Only
  • 28. Hand washing - Reduce bio-burden - With water-based soaps - Often forgotten step
  • 29. Rubbing the lens • 10-15 sec on each side • To and fro action • Removal of environmental & protein deposits • Reduces risks of infections
  • 30. Consumer’s perception of No Rub • Simply put the lenses into lens case after removal • No digital cleaning, No rinsing • Simple, carefree, convenient lens care • Reduced usage of lens care solution
  • 31. Essential Steps of Care & Maintenance ½ Cleaning ½ Rinsing ½ Disinfecting ½ Extra Steps - Protein Removal - Lubricating / Re-wetting
  • 32. Rinsing • Wash off loosened debris • Decrease risk of deposit related problems
  • 33. Essential Steps of Care & Maintenance ½ Cleaning ½ Rinsing ½ Disinfecting ½ Extra Steps - Protein Removal - Lubricating / Re-wetting
  • 34. Disinfecting System ½ Kill or Deactivate potentially pathogenic organisms including -Bacteria -Fungi -Viruses -Amoebas ½ Maintain lens hydration  stable parameters
  • 35. Disinfection • Store the lenses for at least 4 hours in FRESH solution • Decreases the risk of infections
  • 36. Types of Disinfection Heat - Thermal Unit - Microwave Chemical - Oxidative - Hydrogen peroxide - Chlorine - Cold Chemicals - Various disinfectants
  • 37. Thermal Disinfection • Original form of disinfection - discontinued in the market • Procedures – Clean and rinse lenses – Place lenses in fresh saline in lens case – Heat to 70° - 80°C for 10-20 minutes – After heat cycle, allow lenses to cool before use
  • 38. Thermal Disinfection Advantages: • Short disinfection cycle times • Highly effective antimicrobial action • Low risk of toxic or allergic reactions Disadvantages: • Incompatible with some lenses, e.g. high water content; may cause deformation & discoloration • Increased protein deposition (cook the protein onto the lens) & causes allergic response • Suitable electrical power for heat units may not always be available
  • 40. Chemical Disinfection ½ Disinfection achieved by the presence preservative - Thiomersal, Chlorhexidine, Sorbic acid ½ Disinfection depends on the concentration and type of preservative ½ Preservatives are potential irritants though rare
  • 41. Modern Chemical Disinfectants • Used in Multi-Purpose (All-in-one) Solutions: • Polyaminopropyl biguanide (PABA, PHMB) • Quaternary-ammonia (Polyquad) & Aldox Much less incidence of solution sensitivity than older generation of disinfectants. Because the molecules specifically bind to cell membrane of micro-organism rather than human cells. Bacteria Human eye
  • 42. Multipurpose Solutions Single bottle of solution for cleaning, rinsing, disinfection, & removing protein Advantages: • Simple, convenient, easy transport • Enhanced safety due to lower toxicity & complications • Doesn’t cause protein denaturation • Improved compliance Disadvantages: • Small incidence of mild sensitivity reactions
  • 43. Hydrogen Peroxide Advantages: • Preservative free – theoretically less allergy • Effective disinfection Disadvantages: • Inflexible neutralization time (lens must be fully neutralized before use) • H2O2 concentration decreased rapidly (3% to 1% in <10mins) - decreased anti-microbial efficacy • Not suitable for all lens types • Potential for irritation on incomplete neutralization • Possible recontamination
  • 44. Choice of Lens Care System SCL Heat MPS Hydrogen Peroxide Low water,    Non-ionic High water, Some  * Non-ionic Low water,    Ionic High water,   * Ionic * Bleaches color in cosmetic CLs
  • 45. Recommendations ½ Discard solution everyday ½ Rub and Rinse step is essential with combination solution ½ Keep nozzle closed ½ Narrow openings ½ Clean and rinse well ½ Soak for recommended time
  • 46. Essential Steps of Care & Maintenance ½ Cleaning ½ Rinsing ½ Disinfecting ½ Extra Steps - Protein Removal - Lubricating / Re-wetting
  • 47. Protein Removers ½ Effectively remove protein deposits ½ Have no effect on most other deposits ½ React by breaking protein molecules ½ For heavy depositors; conventional lens user
  • 48. Protein Removal Procedure ½ Use regularly after daily wear and rinsing step ½ Lenses should be soaked in enzyme, dissolve in solution / saline for 15 min or over night depending on manufacturer ½ Lenses should be thoroughly rubbed and rinsed again afterwards
  • 49. Essential Steps of Care & Maintenance ½ Cleaning ½ Rinsing ½ Disinfecting ½ Extra Steps - Protein Removal - Lubricating / Re-wetting
  • 50. Rewetting or Lubricating Drops ½ Alleviating signs of dryness and discomfort ½ Flushing irritation particles from eye and CL ½ Rehydrating lens
  • 51. Care for Lens Cases ½ Scrub with new tooth brush using cleaning solution weekly ½ Rinse with saline or disinfecting solution ½ Air dry up-side down ½ Replace case regularly
  • 52. Dos and Don'ts of CL care and maintenance
  • 53. Do-s
  • 54. Always wash your hands before handling contact lenses Check the position of lenses before insertion
  • 55. Cosmetics/Make-up Put your contact lenses in • after applying hair products like hairspray • before applying cosmetics, especially eye makeup.
  • 56. Instruction for eye makeup • Insert your lenses before applying make up • Remove your lenses before taking your makeup off.
  • 57. Avoid Harmful or Irritating Fumes while the Lenses Are on
  • 58. Do Rinse the Lenses • Always before inserting the lens and after removing it from the eye • Rinse the lens with contact lenses solution suggested by your practitioner
  • 59. Clean and change the solution in the lens case Daily Keep your contact lenses either in your eyes or in your lens case
  • 61. Do not let hair spray or other cosmetic aerosols come in contact with your lenses. Avoid Long and Dirty Nails
  • 62. Do not Swim with contact lenses if Yes with swimming goggles only
  • 63. Don’t sleep with contact lenses • Remove your lenses before going to sleep Your cornea may not get the necessary oxygen* while you are sleeping. * Continuous wear lenses or Extended wear lenses with High Dk can be used upon practitioner’s recommendations
  • 64. Additional Tips for Hygienic CL Wear • Do not mix solution types and brands • Never soak/store lenses in saline or tap water • Don’t put your solutions and lens case in the toilet or refrigerator • Don’t touch the tip of the any contact lens solution • Don’t use any topical eye drops when wearing lenses
  • 65. Dirty lenses can cause infection / inflammation
  • 66. Immediate contact with ECP • If your eyes get red and irritated or if you feel any pain remove your lenses and contact your eye care practitioner
  • 67. How to avoid infection? • Deposits can be avoided by maintaining a good lens care regimen • Cleaning • Disinfection • Following the instruction • Shorter is better – Disposables, small packs of solution (120ml or 360ml rather than 500ml)
  • 68. Why disposable ? • More comfortable • Healthy • More hygeinic • Convenience of spare pair at hand • Longer wearing time • Contact lenses related infection & complication reduces in disposables
  • 69. How to enhance compliance? • Educate staff & the patient - Simple written & verbal instructions - Reinforce few key points many times - Practical demonstration/visuals • Review lens care at every visit • Keep patients coming back for more - Compliance packs/offers - Recall system - Regular contact through mailers
  • 70. Summary Minimized adverse reactions achieved by : • clean, well fitted lenses • adequate physiological performance • appropriate choice of care system • regular monitoring of patient • patient compliance

Editor's Notes

  1. When deposits accumulate on the contact lens, the following signs and symptoms may occur: *vision decrease *decrease in contact lens wetting ability *foreign body sensation, discomfort *allergic reaction, GPC *medium for adherence of microorganisms, increasing risk of infection
  2. Example of CL materials under FDA classificxation Group 1 ( &lt;50% H 2 O, nonionic polymers) telfilcon, tetrafilcon A, crofilcon, helfilcon, mafilcon, polymacon , lotrafilcon A. Group 2 ( &gt;50% H 2 O, nonionic polymers) lidofilcon B, surfilcon A, lidofilcon A, netrafilcon A, hefilcon C, alfafilcon A, omafilcon A, vasurfilcon A, hioxifilcon A, nelfilcon A, hilafilcon A Group 3 ( &lt;50% H 2 O, ionic polymers) bufilcon A, deltafilcon A, droxfilcon A, phemfilcon A, ocufilcon, balafilcon A Group 4 ( &gt;50% H 2 O, ionic polymers) perfilcon, etafilcon A, focofilcon A, ocufilcon B, ocufilcon C, ocufilcon D, ocufilcon E, phemfilcon A, methafilcon A methafilcon B, vilfilcon A