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DIGESTION 
AND 
ABSORPTION 
•HSE Zoology blog •1
MAJOR COMPONENTS OF FOOD 
• Carbohydrates 
• Proteins 
• Fats 
• Vitamins 
• Minerals 
• Water 
•HSE Zoology blog •2
DIGESTION 
• The process of 
conversion of 
complex food 
substances to simple 
absorbable form is 
called digestion. 
•HSE Zoology blog •3
HUMAN DIGESTIVE 
SYSTEM 
Alimentary canal 
Associated glands 
•HSE Zoology blog •4
DIGESTIVE 
SYSTEM OF MAN 
•HSE Zoology blog •5
ORAL CAVITY 
(BUCCAL CAVITY) 
• Teeth 
• Tongue 
• Palate(roof) 
•HSE Zoology blog •6
TEETH 
Dentition 
Refers the number, kinds and 
arrangement of teeth 
Thecodont 
Heterodont 
Diphyodont 
•HSE Zoology blog •7
THECODONT 
• Teeth are placed in 
jaw sockets 
•HSE Zoology blog •8
HETERODONT 
• Teeth are different types or dissimilar 
Incisors 
Canine 
Premolars 
Molars 
•HSE Zoology blog •9
DIPHYODONT 
• Teeth appear twice in 
the whole life 
• Milk teeth 
• Permanent teeth 
•HSE Zoology blog •10
The kind and number of teeth are explained in the 
form of formula is called dental formula. 
• Adult 32 
permanent teeth 
• Incisors 2/2 
• Canine 1/1 
• Premolars 2/2 
• Molars 3/3 
• Child 20 milk 
teeth 
• Incisors 2/2 
• Canine 1/1 
• Premolars 0/0 
• Molars 2/2 
DENTAL FORMULA 
•HSE Zoology blog •11
WISDOM TEETH 
• Third molar appears 
after the age of 20 years 
and hence is called 
wisdom teeth. 
•HSE Zoology blog •12
STRUCTURE OF TOOTH 
Crown 
Neck 
Root 
Odontoblast 
Found in the dental 
pulp secrete dentine 
•HSE Zoology blog •13
TONGUE 
• Freely movable 
muscular organ 
attached to the floor of 
the buccal cavity by 
frenulum. 
•HSE Zoology blog •14
TONGUE 
• The upper surface of 
the tongue has small 
projections called 
papillae, some of 
which bear taste 
buds. 
•HSE Zoology blog •15
PHARYNX 
• Common passage for 
digestive and 
respiratory system. 
• Opening of oesophagus 
• Opening of larynx - 
Glottis 
•HSE Zoology blog •16
GLOTTIS 
• Glottis is guarded by a 
flap of tissue called 
epiglottis. 
• When food materials 
pass through the 
pharynx the epiglottis 
closes the glottis. 
•HSE Zoology blog •17
OESOPHAGUS 
• Narrow muscular tube 
• 30 cm long 
• Leads to stomach 
• Pass through the 
diaphragm (a muscular 
partition that separates 
thorax from abdomen). 
•HSE Zoology blog •18
OESOPHAGEAL SPHINCTER 
(GASTRO OESOPHAGIAL SPHINCTER) 
• Posterior region of the 
oesophagus there is a 
ring of muscle called 
oesophagial sphincter. 
• It controls the opening 
of the oesophagus into 
the stomach. 
•HSE Zoology blog •19
PERISTALSIS 
• The movement of food 
materials in the 
esophagus is effected 
by the wave like 
contraction and 
relaxation of 
longitudinal and circular 
muscles of the 
esophagus is known as 
peristalsis. 
•HSE Zoology blog •20
STOMACH 
• Large muscular ‘J’ 
shaped sac. 
• Lying just below the 
diaphragm in the 
abdominal cavity. 
• Three major parts 
– Cardiac 
– Fundic 
– Pyloric 
•HSE Zoology blog •21
PYLORIC SPHINCTER 
• The opening of the 
stomach into the 
duodenum is guarded 
by pyloric sphincter. 
• Controls the flow of 
food to the intestine. 
•HSE Zoology blog •22
SMALL INTESTINE 
• Long, highly coiled, 
narrow tube 
• Seven metres long 
• 2.5 cm diametre 
• Divided in to 
duodenum, jejunum & 
ileum. 
•HSE Zoology blog •23
DUODENUM 
• First part of SI 
• ‘U’ shaped 
• Area of digestion 
• Receives common 
opening of the bile 
and pancreatic duct. 
•HSE Zoology blog •24
JEJUNUM 
• Coiled and longer 
•HSE Zoology blog •25
ILEUM 
• Highly coiled 
• Opens into the large 
intestine 
• Area of absorption 
•HSE Zoology blog •26
LARGE INTESTINE 
• 1.5 metres long 
• Differentiated into 
Caecum , Colon & 
Rectum 
•HSE Zoology blog •27
CAECUM 
• Small blind sac (at the 
junction of SI &LI) 
• Plays no role in Nutrient 
absorption. 
• It hosts some symbiotic 
microorganisms. 
• Caecum bears a finger like 
out growth of unknown 
function known as 
Vermiform Appendix. 
•HSE Zoology blog •28
COLON 
( Pelvic colon) 
•HSE Zoology blog •29
RECTUM 
• Temporary storage of 
faeces 
• Rectum opens out by 
Anus. 
•HSE Zoology blog •30
HISTOLOGY OF HUMAN GUT 
( Outer most ) 
forms a fibrous coat 
Loose connective tissue layer 
with blood & lymph vessels 
(Inner most)-made of 
secretary & absorptive cells 
Smooth muscle 
•HSE Zoology blog •31
RUGAE 
• Mucosal layer forms 
irregular fold in the 
stomach called rugae. 
•HSE Zoology blog •32
VILLI 
• (Sing:- Villus) 
• Mucosal layer forms 
small finger like 
folding in the small 
intestine called Villi 
• A villus is about 0.5 to 
1 mm long 
Villus 
•HSE Zoology blog •33
VILLI 
•HSE Zoology blog •34
VILLI 
•HSE Zoology blog •35
VILLI 
•HSE Zoology blog •36
•HSE Zoology blog •37
MICROVILLI 
• Each villus has 
numerous electron 
microscopic 
evaginations called 
microvilli. 
• Both villi & micro villi 
increases the surface 
area for digestion and 
absorption of food 
•HSE Zoology blog •38
DIGESTIVE GLANDS 
• Salivary glands 
• Pancreas 
• Liver 
• Gastric glands 
• Intestinal glands 
•HSE Zoology blog •39
DIGESTIVE ENZYMES 
• Hydrolyses 
Group of enzymes 
released from the cells 
digestive system play a 
major role in the extra 
cellular digestion in 
human 
• Carbohydrase ( 
amylase ) carbohydrate 
digesting 
E.g.: ptyalin, maltose etc 
• Proteases (protein 
digesting) 
Eg: amino peptidase, 
dipeptidase 
. Lipase (lipid digesting) 
•HSE Zoology blog •40
SALIVARY GLANDS 
• Secrete saliva 
• Found in buccal cavity 
• Three pairs of salivary 
glands 
1.Parotid glands 
(largest) 
2.Sub lingual glands 
3.Sub maxillary 
(Sub mandibular) 
•HSE Zoology blog •41
SALIVA 
• Derived from blood plasma 
• Secrete 1.5 liters of saliva 
per day 
• Slightly alkaline 
• Contain water & electrolyte 
(Na+, K+, Cl-, HCO3 
-) 
• Mucin, ptyalin, lyzozyme & 
inorganic salts 
• Ptyalin digest starch in to 
maltose 
•HSE Zoology blog •42
LIVER 
• Largest gland in the 
human body 
• Weighs about 1.5 kg in 
adult man 
• Bi lobed 
• Secrete bile 
•HSE Zoology blog •43
• Each lobe is separated 
into numerous tiny 
hepatic lobules, which are 
the functional units. 
• A lobule is formed of 
numerous hepatic cells – 
bile is secreted by hepatic 
cells 
• Each lobule is covered by 
a thin connective tissue 
sheath called Glisson’s 
capsule 
Glisson’s 
capsule 
LIVER 
•HSE Zoology blog •44
HEPATIC LOBULES 
•HSE Zoology blog •45
GALL BLADDER 
• Bile is stored and 
Concentrated in a thin 
muscular sac called 
gall bladder. 
• Capacity- 40 – 60 ml 
• Absent in whale, 
horses, rats etc. 
•HSE Zoology blog •46
BILE 
• Golden yellow or greenish fluid 
• Alkaline nature 
• Bile pigments (product of dead RBC) (biliverdin & bilirubin) 
• Bile salts, 
• cholesterol, 
• phospholipids 
• Bile salts play a very important role in the emulsification of fat 
•HSE Zoology blog •47
GALL BLADDER 
• The duct of gall 
bladder (cystic duct) 
along with hepatic 
duct from the liver 
forms a common bile 
duct. 
•HSE Zoology blog •48
GALL BLADDER 
• The bile duct and 
pancreatic duct opens 
together into the 
duodenum as common 
hepato - pancreatic 
duct, which is guarded 
by a sphincter called 
sphincter of Oddi. 
Hepato - Pancreatic duct 
•HSE Zoology blog •49
PANCREAS 
• Located between stomach 
& duodenum 
• Second largest glands 
• Heterocrine gland (both 
exocrine &endocrine) 
• Pancreatic duct opens into 
the duodenum along with 
bile duct 
• Secrete pancreatic juice. 
•HSE Zoology blog •50
PANCREATIC JUICE 
• Alkaline nature 
• Trypsinogen , 
Chymotrypsinogen 
Proarboxypeptidase, 
Amylopsin (p. amylase) 
• Steapsin (pancreatic 
lipase) 
• Nuclease (Nucleic acid 
digesting enzyme) 
•HSE Zoology blog •51
GASTRIC GLANDS 
• Found on the wall of 
stomach 
• Formed of three kinds of 
cells 
1. Mucous cells 
2. Chief cells or 
Zymogen cells 
3. Oxyntic cells 
or Parital cells 
•HSE Zoology blog •52
mucus secreting 
GASTRIC GLANDS 
•HSE Zoology blog •53
GASTRIC GLANDS 
•HSE Zoology blog •54
GASTRIC SECRETIONS 
Name of Cell Function 
Mucous cells (Goblet cells) Secrete mucous 
Oxyntic cells or Parital cells 
Secretion of HCl and intrensic 
factor (factor essential for the 
absorption of vitamin B12) 
Chief cells or Zymogen cells 
Secretion of enzymes such as 
pepsin , rennin, lipase etc. 
•HSE Zoology blog •55
HCl 
• Inactivate the secretion of 
salivary amylase. 
• Kills micro organism 
• Lowers the pH of the 
stomach (1.5 to 2.5) 
• Activate proenzyme 
pepsinogen to active pepsin. 
•HSE Zoology blog •56
INTESTINAL GLANDS 
• Simple tubular glands found throughout SI 
• Two types 
Crypts of Lieberkuhn 
Glands of Brunner 
•HSE Zoology blog •57
CRYPTS OF LIEBERKUHN 
• Goblet cells – Mucous secreting 
• Paneth cells – Enzyme secreting 
Many surface area of gastro intestinal tract are 
lined by evaginations of the epithelium in to sub 
mucosa similar to pits. These pits of the 
intestine are called Crypts of Lieberkuhn 
Paneth cells 
Goblet cells 
villus 
crypt 
•HSE Zoology blog •58
GLANDS OF BRUNNER ( DUODENAL GLANDS) 
• Confined to the sub 
mucosa of the 
duodenum and 
secrete mucus only 
•HSE Zoology blog •59
INTESTINAL JUICE 
(SUCCUS ENTERICUS) 
• Collective secretions of 
intestinal glands 
• Alkaline nature 
• Contain enzymes , 
mucous & inorganic 
salts. 
• Proteases 
Aminopeptidase, 
Dipeptidase 
• Amylase 
Maltase, Isomaltase 
Lactase, Surcease 
• Lipase 
• Enterokinase 
•HSE Zoology blog •60
DIGESTION 
• The teeth and tongue with 
the help of saliva masticate 
and mix up the food into 
bolus. 
• The bolus is conveyed to 
pharynx and then to 
oesophagus by swallowing or 
deglutition. 
•HSE Zoology blog •61
DIGESTION 
• The stomach stores the food 4-5 hrs. The food 
mixes thoroughly with acidic gastric juice to 
form paste.- Chyme 
•HSE Zoology blog •62 
chyme
Buccal cavity 
Salivary amylase 
• Starch 
Starch Maltose 
Maltose 
CARBOHYDRATE 
DIGESTION 
Stomach 
No carbohydrate 
digestion 
Small Intestine 
Starch Maltose 
Maltose 2 Glucose 
Lactose Glucose + 
Galactose 
Sucrose Glucose + 
Fructose 
P. amylase 
Maltase 
Lactase 
Sucrase 
•HSE Zoology blog •63
Buccal cavity 
No protein digestion 
Stomach 
HCl 
Pepsinogen Pepsin 
Protein 
Pepsin Peptones + 
Proteoses 
Peptones = larger peptides 
Proteoses = smaller peptides 
Small intestine 
Trypsinogen Enterokinase Trypsin 
Chymotrypsinogen Chymotrypsin 
Procarboxy 
peptidase 
Carboxy 
peptidase 
Proteins 
Peptones 
Proteoses 
Dipeptides 
Trypsin / Chymotrypsin 
Carboxy peptidase 
Dipeptidase 
Dipeptides Amino acids 
PROTEIN DIGESTION 
•HSE Zoology blog •64
Buccal cavity 
No protein digestion 
Stomach 
Gastric lipase hydrolyses 
only a small amount of 
fat Small intestine 
Fat Bile Fat droplets 
Emulsification 
Fat 
Pancreatic lipase 
Diglyceride 
Monoglycerides 
Fatty acids & Glycerol 
FAT DIGESTION 
•HSE Zoology blog •65
NUCLEIC ACID DIGESTION 
Small Intestine 
Nucleic acids Nucleotides Nucleosides Sugar + Bases 
•HSE Zoology blog •66
END PRODUCTS OF DIGESTION 
Carbohydrates 
Glucose 
Fructose 
Galactose 
Proteins 
Amino acids 
Fats 
Fatty acids 
glycerol 
•HSE Zoology blog •67
• Complete digestion of 
food take place in the 
duodenum. The fully 
digested food is semi 
fluid in nature and is 
known as Chyle 
DIGESTION 
•HSE Zoology blog •68
ABSORPTION OF DIGESTED PRODUCTS 
• Absorption is the process by 
which the end products of 
digestion pass through the 
intestinal mucosa 
( transported through the 
intestinal mucosa) into the 
blood or lymph 
• The end products of digestion 
are absorbed in the jejunum 
and ileum regions of small 
intestine. 
•HSE Zoology blog •69
ABSORPTION 
Absorption is carried out by 
– Passive transport 
– Facilitated transport 
– Active transport 
•HSE Zoology blog •70
PASSIVE TRANSPORT 
• Small amounts of monosaccharide like glucose, amino acids, 
and some of electrolytes like chloride ions are generally 
absorbed by simple diffusion. 
•HSE Zoology blog •71
•HSE Zoology blog •72
FACILITATED TRANSPORT 
• Fructose and some 
amino acids are 
absorbed with the help 
of carrier ions like 
sodium. This 
mechanism is called 
facilitated transport. 
•HSE Zoology blog •73
ACTIVE TRANSPORT 
• Requires energy 
• Various nutrients like 
amino acids, 
monosaccharide like 
glucose, electrolytes like 
Na+ are reabsorbed into 
the blood by active 
transport. 
•HSE Zoology blog •74
•HSE Zoology blog •75
ABSORPTION OF FAT 
• Fatty acids and glycerol insoluble in water so they cannot be 
absorbed directly from the lumen of the intestine. 
• With the help of bile salts & phospholipids the fatty acids and 
glycerol are converted into small spherical water soluble droplets 
called micelles. 
•HSE Zoology blog •76
ABSORPTION OF FAT 
Micelles are reformed into very small protein coated fat 
globules called chylomicrons. Which are transported in to 
the lymph vessels (lactales)in the villi. 
•HSE Zoology blog •77
ABSORPTION OF FAT 
•HSE Zoology blog •78
LARGE INTESTINE 
Functions 
Absorption of water, 
minerals and certain 
drugs. 
Secretion of mucus which 
helps in adhering waste. 
• No significant digestive 
activity occurs in the 
large intestine. 
•HSE Zoology blog •79
LARGE INTESTINE 
• The undigested and 
unabsorbed substances 
(faeces) enters into the 
caecum of the large 
intestine through the 
ileo caecal valve, which 
prevents the back flow 
of faecal matter. 
•HSE Zoology blog •80
EGESTION 
• The egestion of faeces 
to the outside through 
the anal opening 
(defaecation) is a 
voluntary process and is 
carried out by a mass 
peristaltic movement. 
•HSE Zoology blog •81
THE SUMMARY OF ABSORPTION IN DIFFERENT PARTS OF 
DIGESTIVE SYSTEM 
Oral cavity Stomach Small Intestine Large 
Intestine 
Certain drugs 
coming in 
contact with the 
mucosa of the 
mouth and 
lower side of the 
tongue are 
absorbed into 
the blood 
capillaries lining 
them. 
Water, simple 
sugars, alcohol 
Glucose Fructose 
Fatty acids 
Glycerol 
Amino acids 
Water , some 
minerals, 
drugs 
•HSE Zoology blog •82
DISORDERS OF DIGESTIVE SYSTEM 
• Infections of the 
digestive system 
are caused by 
bacteria, virus, 
parasites like tape 
worm, thread 
worm, round 
worm, hook 
worm, pinworm 
etc. 
Bacteria 
Tape worm 
Virus 
Pinworm 
•HSE Zoology blog •83 
Thread worm
VOMITING 
• It is the ejection of stomach 
content through the mouth. 
•HSE Zoology blog •84
DIARRHOEA 
• The abnormal 
frequency of bowel 
movement and 
increased liquidity of 
faecal discharge is 
known as diarrhoea. 
• It reduces the 
absorption of food. 
•HSE Zoology blog •85
JAUNDICE 
• The liver is affected, skin, eyes turn 
yellow due to the deposition of bile 
pigments. 
•HSE Zoology blog •86
CONSTIPATION 
• The faeces are retained 
with in the rectum as 
the bowel movement 
occur irregularly. 
•HSE Zoology blog •87
INDIGESTION 
• The food is not properly 
digested leading to the 
feeling of fullness. 
• The cause of indigestion 
are inadequate enzyme 
secretion, anxiety, food 
poisoning, overeating 
and spicy food. 
•HSE Zoology blog •88

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Digestion and absorption

  • 1. DIGESTION AND ABSORPTION •HSE Zoology blog •1
  • 2. MAJOR COMPONENTS OF FOOD • Carbohydrates • Proteins • Fats • Vitamins • Minerals • Water •HSE Zoology blog •2
  • 3. DIGESTION • The process of conversion of complex food substances to simple absorbable form is called digestion. •HSE Zoology blog •3
  • 4. HUMAN DIGESTIVE SYSTEM Alimentary canal Associated glands •HSE Zoology blog •4
  • 5. DIGESTIVE SYSTEM OF MAN •HSE Zoology blog •5
  • 6. ORAL CAVITY (BUCCAL CAVITY) • Teeth • Tongue • Palate(roof) •HSE Zoology blog •6
  • 7. TEETH Dentition Refers the number, kinds and arrangement of teeth Thecodont Heterodont Diphyodont •HSE Zoology blog •7
  • 8. THECODONT • Teeth are placed in jaw sockets •HSE Zoology blog •8
  • 9. HETERODONT • Teeth are different types or dissimilar Incisors Canine Premolars Molars •HSE Zoology blog •9
  • 10. DIPHYODONT • Teeth appear twice in the whole life • Milk teeth • Permanent teeth •HSE Zoology blog •10
  • 11. The kind and number of teeth are explained in the form of formula is called dental formula. • Adult 32 permanent teeth • Incisors 2/2 • Canine 1/1 • Premolars 2/2 • Molars 3/3 • Child 20 milk teeth • Incisors 2/2 • Canine 1/1 • Premolars 0/0 • Molars 2/2 DENTAL FORMULA •HSE Zoology blog •11
  • 12. WISDOM TEETH • Third molar appears after the age of 20 years and hence is called wisdom teeth. •HSE Zoology blog •12
  • 13. STRUCTURE OF TOOTH Crown Neck Root Odontoblast Found in the dental pulp secrete dentine •HSE Zoology blog •13
  • 14. TONGUE • Freely movable muscular organ attached to the floor of the buccal cavity by frenulum. •HSE Zoology blog •14
  • 15. TONGUE • The upper surface of the tongue has small projections called papillae, some of which bear taste buds. •HSE Zoology blog •15
  • 16. PHARYNX • Common passage for digestive and respiratory system. • Opening of oesophagus • Opening of larynx - Glottis •HSE Zoology blog •16
  • 17. GLOTTIS • Glottis is guarded by a flap of tissue called epiglottis. • When food materials pass through the pharynx the epiglottis closes the glottis. •HSE Zoology blog •17
  • 18. OESOPHAGUS • Narrow muscular tube • 30 cm long • Leads to stomach • Pass through the diaphragm (a muscular partition that separates thorax from abdomen). •HSE Zoology blog •18
  • 19. OESOPHAGEAL SPHINCTER (GASTRO OESOPHAGIAL SPHINCTER) • Posterior region of the oesophagus there is a ring of muscle called oesophagial sphincter. • It controls the opening of the oesophagus into the stomach. •HSE Zoology blog •19
  • 20. PERISTALSIS • The movement of food materials in the esophagus is effected by the wave like contraction and relaxation of longitudinal and circular muscles of the esophagus is known as peristalsis. •HSE Zoology blog •20
  • 21. STOMACH • Large muscular ‘J’ shaped sac. • Lying just below the diaphragm in the abdominal cavity. • Three major parts – Cardiac – Fundic – Pyloric •HSE Zoology blog •21
  • 22. PYLORIC SPHINCTER • The opening of the stomach into the duodenum is guarded by pyloric sphincter. • Controls the flow of food to the intestine. •HSE Zoology blog •22
  • 23. SMALL INTESTINE • Long, highly coiled, narrow tube • Seven metres long • 2.5 cm diametre • Divided in to duodenum, jejunum & ileum. •HSE Zoology blog •23
  • 24. DUODENUM • First part of SI • ‘U’ shaped • Area of digestion • Receives common opening of the bile and pancreatic duct. •HSE Zoology blog •24
  • 25. JEJUNUM • Coiled and longer •HSE Zoology blog •25
  • 26. ILEUM • Highly coiled • Opens into the large intestine • Area of absorption •HSE Zoology blog •26
  • 27. LARGE INTESTINE • 1.5 metres long • Differentiated into Caecum , Colon & Rectum •HSE Zoology blog •27
  • 28. CAECUM • Small blind sac (at the junction of SI &LI) • Plays no role in Nutrient absorption. • It hosts some symbiotic microorganisms. • Caecum bears a finger like out growth of unknown function known as Vermiform Appendix. •HSE Zoology blog •28
  • 29. COLON ( Pelvic colon) •HSE Zoology blog •29
  • 30. RECTUM • Temporary storage of faeces • Rectum opens out by Anus. •HSE Zoology blog •30
  • 31. HISTOLOGY OF HUMAN GUT ( Outer most ) forms a fibrous coat Loose connective tissue layer with blood & lymph vessels (Inner most)-made of secretary & absorptive cells Smooth muscle •HSE Zoology blog •31
  • 32. RUGAE • Mucosal layer forms irregular fold in the stomach called rugae. •HSE Zoology blog •32
  • 33. VILLI • (Sing:- Villus) • Mucosal layer forms small finger like folding in the small intestine called Villi • A villus is about 0.5 to 1 mm long Villus •HSE Zoology blog •33
  • 34. VILLI •HSE Zoology blog •34
  • 35. VILLI •HSE Zoology blog •35
  • 36. VILLI •HSE Zoology blog •36
  • 38. MICROVILLI • Each villus has numerous electron microscopic evaginations called microvilli. • Both villi & micro villi increases the surface area for digestion and absorption of food •HSE Zoology blog •38
  • 39. DIGESTIVE GLANDS • Salivary glands • Pancreas • Liver • Gastric glands • Intestinal glands •HSE Zoology blog •39
  • 40. DIGESTIVE ENZYMES • Hydrolyses Group of enzymes released from the cells digestive system play a major role in the extra cellular digestion in human • Carbohydrase ( amylase ) carbohydrate digesting E.g.: ptyalin, maltose etc • Proteases (protein digesting) Eg: amino peptidase, dipeptidase . Lipase (lipid digesting) •HSE Zoology blog •40
  • 41. SALIVARY GLANDS • Secrete saliva • Found in buccal cavity • Three pairs of salivary glands 1.Parotid glands (largest) 2.Sub lingual glands 3.Sub maxillary (Sub mandibular) •HSE Zoology blog •41
  • 42. SALIVA • Derived from blood plasma • Secrete 1.5 liters of saliva per day • Slightly alkaline • Contain water & electrolyte (Na+, K+, Cl-, HCO3 -) • Mucin, ptyalin, lyzozyme & inorganic salts • Ptyalin digest starch in to maltose •HSE Zoology blog •42
  • 43. LIVER • Largest gland in the human body • Weighs about 1.5 kg in adult man • Bi lobed • Secrete bile •HSE Zoology blog •43
  • 44. • Each lobe is separated into numerous tiny hepatic lobules, which are the functional units. • A lobule is formed of numerous hepatic cells – bile is secreted by hepatic cells • Each lobule is covered by a thin connective tissue sheath called Glisson’s capsule Glisson’s capsule LIVER •HSE Zoology blog •44
  • 45. HEPATIC LOBULES •HSE Zoology blog •45
  • 46. GALL BLADDER • Bile is stored and Concentrated in a thin muscular sac called gall bladder. • Capacity- 40 – 60 ml • Absent in whale, horses, rats etc. •HSE Zoology blog •46
  • 47. BILE • Golden yellow or greenish fluid • Alkaline nature • Bile pigments (product of dead RBC) (biliverdin & bilirubin) • Bile salts, • cholesterol, • phospholipids • Bile salts play a very important role in the emulsification of fat •HSE Zoology blog •47
  • 48. GALL BLADDER • The duct of gall bladder (cystic duct) along with hepatic duct from the liver forms a common bile duct. •HSE Zoology blog •48
  • 49. GALL BLADDER • The bile duct and pancreatic duct opens together into the duodenum as common hepato - pancreatic duct, which is guarded by a sphincter called sphincter of Oddi. Hepato - Pancreatic duct •HSE Zoology blog •49
  • 50. PANCREAS • Located between stomach & duodenum • Second largest glands • Heterocrine gland (both exocrine &endocrine) • Pancreatic duct opens into the duodenum along with bile duct • Secrete pancreatic juice. •HSE Zoology blog •50
  • 51. PANCREATIC JUICE • Alkaline nature • Trypsinogen , Chymotrypsinogen Proarboxypeptidase, Amylopsin (p. amylase) • Steapsin (pancreatic lipase) • Nuclease (Nucleic acid digesting enzyme) •HSE Zoology blog •51
  • 52. GASTRIC GLANDS • Found on the wall of stomach • Formed of three kinds of cells 1. Mucous cells 2. Chief cells or Zymogen cells 3. Oxyntic cells or Parital cells •HSE Zoology blog •52
  • 53. mucus secreting GASTRIC GLANDS •HSE Zoology blog •53
  • 54. GASTRIC GLANDS •HSE Zoology blog •54
  • 55. GASTRIC SECRETIONS Name of Cell Function Mucous cells (Goblet cells) Secrete mucous Oxyntic cells or Parital cells Secretion of HCl and intrensic factor (factor essential for the absorption of vitamin B12) Chief cells or Zymogen cells Secretion of enzymes such as pepsin , rennin, lipase etc. •HSE Zoology blog •55
  • 56. HCl • Inactivate the secretion of salivary amylase. • Kills micro organism • Lowers the pH of the stomach (1.5 to 2.5) • Activate proenzyme pepsinogen to active pepsin. •HSE Zoology blog •56
  • 57. INTESTINAL GLANDS • Simple tubular glands found throughout SI • Two types Crypts of Lieberkuhn Glands of Brunner •HSE Zoology blog •57
  • 58. CRYPTS OF LIEBERKUHN • Goblet cells – Mucous secreting • Paneth cells – Enzyme secreting Many surface area of gastro intestinal tract are lined by evaginations of the epithelium in to sub mucosa similar to pits. These pits of the intestine are called Crypts of Lieberkuhn Paneth cells Goblet cells villus crypt •HSE Zoology blog •58
  • 59. GLANDS OF BRUNNER ( DUODENAL GLANDS) • Confined to the sub mucosa of the duodenum and secrete mucus only •HSE Zoology blog •59
  • 60. INTESTINAL JUICE (SUCCUS ENTERICUS) • Collective secretions of intestinal glands • Alkaline nature • Contain enzymes , mucous & inorganic salts. • Proteases Aminopeptidase, Dipeptidase • Amylase Maltase, Isomaltase Lactase, Surcease • Lipase • Enterokinase •HSE Zoology blog •60
  • 61. DIGESTION • The teeth and tongue with the help of saliva masticate and mix up the food into bolus. • The bolus is conveyed to pharynx and then to oesophagus by swallowing or deglutition. •HSE Zoology blog •61
  • 62. DIGESTION • The stomach stores the food 4-5 hrs. The food mixes thoroughly with acidic gastric juice to form paste.- Chyme •HSE Zoology blog •62 chyme
  • 63. Buccal cavity Salivary amylase • Starch Starch Maltose Maltose CARBOHYDRATE DIGESTION Stomach No carbohydrate digestion Small Intestine Starch Maltose Maltose 2 Glucose Lactose Glucose + Galactose Sucrose Glucose + Fructose P. amylase Maltase Lactase Sucrase •HSE Zoology blog •63
  • 64. Buccal cavity No protein digestion Stomach HCl Pepsinogen Pepsin Protein Pepsin Peptones + Proteoses Peptones = larger peptides Proteoses = smaller peptides Small intestine Trypsinogen Enterokinase Trypsin Chymotrypsinogen Chymotrypsin Procarboxy peptidase Carboxy peptidase Proteins Peptones Proteoses Dipeptides Trypsin / Chymotrypsin Carboxy peptidase Dipeptidase Dipeptides Amino acids PROTEIN DIGESTION •HSE Zoology blog •64
  • 65. Buccal cavity No protein digestion Stomach Gastric lipase hydrolyses only a small amount of fat Small intestine Fat Bile Fat droplets Emulsification Fat Pancreatic lipase Diglyceride Monoglycerides Fatty acids & Glycerol FAT DIGESTION •HSE Zoology blog •65
  • 66. NUCLEIC ACID DIGESTION Small Intestine Nucleic acids Nucleotides Nucleosides Sugar + Bases •HSE Zoology blog •66
  • 67. END PRODUCTS OF DIGESTION Carbohydrates Glucose Fructose Galactose Proteins Amino acids Fats Fatty acids glycerol •HSE Zoology blog •67
  • 68. • Complete digestion of food take place in the duodenum. The fully digested food is semi fluid in nature and is known as Chyle DIGESTION •HSE Zoology blog •68
  • 69. ABSORPTION OF DIGESTED PRODUCTS • Absorption is the process by which the end products of digestion pass through the intestinal mucosa ( transported through the intestinal mucosa) into the blood or lymph • The end products of digestion are absorbed in the jejunum and ileum regions of small intestine. •HSE Zoology blog •69
  • 70. ABSORPTION Absorption is carried out by – Passive transport – Facilitated transport – Active transport •HSE Zoology blog •70
  • 71. PASSIVE TRANSPORT • Small amounts of monosaccharide like glucose, amino acids, and some of electrolytes like chloride ions are generally absorbed by simple diffusion. •HSE Zoology blog •71
  • 73. FACILITATED TRANSPORT • Fructose and some amino acids are absorbed with the help of carrier ions like sodium. This mechanism is called facilitated transport. •HSE Zoology blog •73
  • 74. ACTIVE TRANSPORT • Requires energy • Various nutrients like amino acids, monosaccharide like glucose, electrolytes like Na+ are reabsorbed into the blood by active transport. •HSE Zoology blog •74
  • 76. ABSORPTION OF FAT • Fatty acids and glycerol insoluble in water so they cannot be absorbed directly from the lumen of the intestine. • With the help of bile salts & phospholipids the fatty acids and glycerol are converted into small spherical water soluble droplets called micelles. •HSE Zoology blog •76
  • 77. ABSORPTION OF FAT Micelles are reformed into very small protein coated fat globules called chylomicrons. Which are transported in to the lymph vessels (lactales)in the villi. •HSE Zoology blog •77
  • 78. ABSORPTION OF FAT •HSE Zoology blog •78
  • 79. LARGE INTESTINE Functions Absorption of water, minerals and certain drugs. Secretion of mucus which helps in adhering waste. • No significant digestive activity occurs in the large intestine. •HSE Zoology blog •79
  • 80. LARGE INTESTINE • The undigested and unabsorbed substances (faeces) enters into the caecum of the large intestine through the ileo caecal valve, which prevents the back flow of faecal matter. •HSE Zoology blog •80
  • 81. EGESTION • The egestion of faeces to the outside through the anal opening (defaecation) is a voluntary process and is carried out by a mass peristaltic movement. •HSE Zoology blog •81
  • 82. THE SUMMARY OF ABSORPTION IN DIFFERENT PARTS OF DIGESTIVE SYSTEM Oral cavity Stomach Small Intestine Large Intestine Certain drugs coming in contact with the mucosa of the mouth and lower side of the tongue are absorbed into the blood capillaries lining them. Water, simple sugars, alcohol Glucose Fructose Fatty acids Glycerol Amino acids Water , some minerals, drugs •HSE Zoology blog •82
  • 83. DISORDERS OF DIGESTIVE SYSTEM • Infections of the digestive system are caused by bacteria, virus, parasites like tape worm, thread worm, round worm, hook worm, pinworm etc. Bacteria Tape worm Virus Pinworm •HSE Zoology blog •83 Thread worm
  • 84. VOMITING • It is the ejection of stomach content through the mouth. •HSE Zoology blog •84
  • 85. DIARRHOEA • The abnormal frequency of bowel movement and increased liquidity of faecal discharge is known as diarrhoea. • It reduces the absorption of food. •HSE Zoology blog •85
  • 86. JAUNDICE • The liver is affected, skin, eyes turn yellow due to the deposition of bile pigments. •HSE Zoology blog •86
  • 87. CONSTIPATION • The faeces are retained with in the rectum as the bowel movement occur irregularly. •HSE Zoology blog •87
  • 88. INDIGESTION • The food is not properly digested leading to the feeling of fullness. • The cause of indigestion are inadequate enzyme secretion, anxiety, food poisoning, overeating and spicy food. •HSE Zoology blog •88