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The NERVOUS SystemThe NERVOUS System
7.01 The three broad functions of7.01 The three broad functions of
the nervous system:the nervous system:
SensorySensory
– senses stimuli from both within the bodysenses stimuli from both within the body
and from the external environmentand from the external environment
IntegrativeIntegrative
– analyzes, interprets, and stores informationanalyzes, interprets, and stores information
about the stimuli it has receives from theabout the stimuli it has receives from the
sensory portion of the nervous systemsensory portion of the nervous system
MotorMotor
– responds to stimuli by some type of actionresponds to stimuli by some type of action
muscular contractionmuscular contraction
glandular secretionglandular secretion
7.02 Describe the general organization of7.02 Describe the general organization of
the nervous system.the nervous system.
Central Nervous System (CNS)Central Nervous System (CNS)
– BrainBrain
– Spinal CordSpinal Cord
Peripheral Nervous System (PNS)Peripheral Nervous System (PNS)
– Spinal Nerves (31 pairs)Spinal Nerves (31 pairs)
– Cranial Nerves (I-XII pairs)Cranial Nerves (I-XII pairs)
– SubdivisionsSubdivisions
Autonomic Nervous System (ANS) - InvolutaryAutonomic Nervous System (ANS) - Involutary
– SympatheticSympathetic
– ParasympatheticParasympathetic
Somatic Nervous System - VoluntarySomatic Nervous System - Voluntary
7.02 The Central Nervous System7.02 The Central Nervous System
(CNS)(CNS)
Brain and Spinal CordBrain and Spinal Cord
CNS FunctionCNS Function
– Sorts incoming sensorySorts incoming sensory
informationinformation
– Generates thoughts andGenerates thoughts and
emotionsemotions
– Forms and stores memoriesForms and stores memories
– Stimulates muscle contractionsStimulates muscle contractions
– Stimulates glandular secretionsStimulates glandular secretions
7.02 Peripheral Nervous System7.02 Peripheral Nervous System
(PNS)(PNS)
Spinal and Cranial NervesSpinal and Cranial Nerves
– Spinal Nerves (31 pairs)Spinal Nerves (31 pairs)
– Cranial Nerves (I-XII pairs)Cranial Nerves (I-XII pairs)
– SubdivisionsSubdivisions
Autonomic Nervous System (ANS) - InvolutaryAutonomic Nervous System (ANS) - Involutary
– SympatheticSympathetic
– ParasympatheticParasympathetic
Somatic Nervous System - VoluntarySomatic Nervous System - Voluntary
CNSCNS
PNSPNS
GreenGreen is the PNSis the PNS
CNSCNS
7.02 The Autonomic7.02 The Autonomic
Nervous System (ANS)Nervous System (ANS)
Contains sensory neurons mainly from theContains sensory neurons mainly from the
viscera that convey information to theviscera that convey information to the
CNSCNS
Contains the efferent neurons that conductContains the efferent neurons that conduct
impulses to smooth muscle, cardiacimpulses to smooth muscle, cardiac
muscle, and glandsmuscle, and glands
Unconscious controlUnconscious control
Two divisions of the ANSTwo divisions of the ANS
– Sympathetic Division - stimulatory effectSympathetic Division - stimulatory effect
– Parasympathetic Division - inhibitory effectParasympathetic Division - inhibitory effect
SympatheticSympathetic
Stimulatory.Stimulatory.
“Fight or Flight”“Fight or Flight”
ParasympatheticParasympathetic
Inhibitory.Inhibitory.
7.02 The Somatic Nervous System7.02 The Somatic Nervous System
(SNS)(SNS)
Made up of sensory neurons thatMade up of sensory neurons that
convey information from the cutaneousconvey information from the cutaneous
and special sense receptors in the head,and special sense receptors in the head,
body wall, and extremities to the CNSbody wall, and extremities to the CNS
Also contains the motor neurons fromAlso contains the motor neurons from
the CNS that conduct impulses to thethe CNS that conduct impulses to the
skeletal musclesskeletal muscles
7.03 List the functions and7.03 List the functions and
structures of neurons.structures of neurons.
The nerve cells responsible for theThe nerve cells responsible for the
special functions of the nervous systemspecial functions of the nervous system
– sensingsensing - remembering- remembering - thinking- thinking
– controlling muscle activitycontrolling muscle activity
– controlling glandular secretionscontrolling glandular secretions
Synapse - the functional relay pointsSynapse - the functional relay points
between two neurons or between abetween two neurons or between a
neuron and an effector organneuron and an effector organ
– Neuromuscular JunctionNeuromuscular Junction
– Neuroglandular JunctionNeuroglandular Junction
7.03 List the functions and7.03 List the functions and
structures of neurons.structures of neurons.
Cell Body (Soma or Perikaryon)Cell Body (Soma or Perikaryon)
– nucleus, cytoplasm, organelles of a neuronnucleus, cytoplasm, organelles of a neuron
Dendrites - tapered, highly branchedDendrites - tapered, highly branched
processes protruding from the cell bodyprocesses protruding from the cell body
– usually very shortusually very short
– AFFERENT FUNCTIONAFFERENT FUNCTION
Axons - long, thin, cylindrical processAxons - long, thin, cylindrical process
– usually myelinatedusually myelinated
– EFFERENT FUNCTIONEFFERENT FUNCTION
NeuronNeuron
NeuronsNeurons
7.03 List the functions and7.03 List the functions and
structures ofstructures of neuroglialneuroglial cells:cells:
Nervous system cells that support,Nervous system cells that support,
nurture and protect the neuronsnurture and protect the neurons
Types of Neuroglia found in theTypes of Neuroglia found in the CNSCNS
– AstrocytesAstrocytes
– OligodendrocytesOligodendrocytes
– MicrogliaMicroglia
– Ependymal CellsEpendymal Cells
Types of Neuroglia found in theTypes of Neuroglia found in the PNSPNS
– Neurolemmocytes (Schwann Cells)Neurolemmocytes (Schwann Cells)
– Satellite CellsSatellite Cells
7.03 Astrocytes (Astroglia)7.03 Astrocytes (Astroglia)
Star-shaped cells with many processesStar-shaped cells with many processes
Forms the Blood Brain Barrier (BBB)Forms the Blood Brain Barrier (BBB)
Forms the pia mater covering the brainForms the pia mater covering the brain
and spinal cord.and spinal cord.
Soaks up excess ions and toxinsSoaks up excess ions and toxins
Participate in brain developmentParticipate in brain development
Facilitates repair for CNS traumaFacilitates repair for CNS trauma
7.03 Astrocyte7.03 Astrocyte
7.03 Microglia7.03 Microglia
Small phagocytic cells that protect theSmall phagocytic cells that protect the
central nervous system by engulfingcentral nervous system by engulfing
and invading microbesand invading microbes
Clears awayClears away
debris fromdebris from
dead cellsdead cells
7.03 Oligodendrocytes7.03 Oligodendrocytes
(Oligodendroglia)(Oligodendroglia)
Oligo- small or fewOligo- small or few
Small glial cells with few processesSmall glial cells with few processes
Form a supporting network around theForm a supporting network around the
neurons by twining around neuronsneurons by twining around neurons
and producing a lipid and proteinand producing a lipid and protein
wrapping around the neuronswrapping around the neurons
((myelin sheathmyelin sheath))
6.03 Oligodendrocyte6.03 Oligodendrocyte
7.03 Ependymal Cells7.03 Ependymal Cells
Neuroglia cells lineNeuroglia cells line
the brain ventriclesthe brain ventricles
and the central canaland the central canal
of the spinal cordof the spinal cord
Form and circulateForm and circulate
cerebral spinal fluidcerebral spinal fluid
(CSF)(CSF)
7.03 Neuroglia of the PNS7.03 Neuroglia of the PNS
(Schwann and Satellite cells)(Schwann and Satellite cells)
Schwann CellsSchwann Cells - Neurolemmocytes- Neurolemmocytes
– Cells responsible for producing the myelinCells responsible for producing the myelin
sheaths around the PNS neuronssheaths around the PNS neurons
Satellite CellsSatellite Cells
– Similar to astrocytesSimilar to astrocytes
– Structural supportStructural support
– soaks up excess ionssoaks up excess ions
and toxinsand toxins
7.03 Schwann Cell Myelination7.03 Schwann Cell Myelination
7.03 Myelination7.03 Myelination
7.03 Myelination7.03 Myelination
The process of developing or producingThe process of developing or producing
a Myelin Sheatha Myelin Sheath
Insulates the axon of a neuronInsulates the axon of a neuron
Increases the speed of nerve impulseIncreases the speed of nerve impulse
conductionconduction
– CNS - oligodendrocytesCNS - oligodendrocytes
– PNS - neurolemmocytes (Schwann Cells)PNS - neurolemmocytes (Schwann Cells)
Guillain-Barre syndrome and MultipleGuillain-Barre syndrome and Multiple
Sclerosis are involved the destruction ofSclerosis are involved the destruction of
the myelin sheaths around the nervethe myelin sheaths around the nerve
7.04 Contrast white and gray7.04 Contrast white and gray
matter of nervous tissue.matter of nervous tissue.
White MatterWhite Matter - the aggregation of- the aggregation of
myelinatedmyelinated processes from manyprocesses from many
neuronsneurons
– Visible upon freshly dissected brain orVisible upon freshly dissected brain or
spinal tissuespinal tissue
– White color is due to myelinationWhite color is due to myelination
Gray MatterGray Matter -- unmyelinatedunmyelinated nerve cellnerve cell
bodies, axons, dendrites, ganglia, andbodies, axons, dendrites, ganglia, and
axon terminalsaxon terminals
– Appears gray because of lack of myelinAppears gray because of lack of myelin
7.04 Gray and White Matter7.04 Gray and White Matter
7.05 Describe the location, and7.05 Describe the location, and
function of CSF.function of CSF.
(ventricles, subarachnoid space)(ventricles, subarachnoid space)
Cavities within the brainCavities within the brain
Lateral ventricles (2) - located within eachLateral ventricles (2) - located within each
hemisphere in the cerebrumhemisphere in the cerebrum
Third ventricle - a vertical slit between theThird ventricle - a vertical slit between the
lateral ventricles and inferior to the rightlateral ventricles and inferior to the right
and left halves of the thalamusand left halves of the thalamus
Fourth ventricle - space between theFourth ventricle - space between the
brainstem and the cerebellumbrainstem and the cerebellum
7.05 Describe the location, and7.05 Describe the location, and
function of CSF.function of CSF.
(Choroid Plexus)(Choroid Plexus)
Network of capillaries in the walls of theNetwork of capillaries in the walls of the
ventriclesventricles
Covered with ependymal cells that form theCovered with ependymal cells that form the
cerebrospinal fluidcerebrospinal fluid
These ependymal cells are so close togetherThese ependymal cells are so close together
they form the blood-brain barrier.they form the blood-brain barrier.
– Selectively permeable barrierSelectively permeable barrier
– Protects the brain and spinal cord fromProtects the brain and spinal cord from
potentially harmful substances in the bloodpotentially harmful substances in the blood
7.05 Blood Supply to the Brain7.05 Blood Supply to the Brain
One of the most metabolically activeOne of the most metabolically active
organs in the bodyorgans in the body
Makes up only 2-3% of body weight butMakes up only 2-3% of body weight but
uses about 20% of available Ouses about 20% of available O22 at restat rest
Well supplied with OWell supplied with O22 and nutrientsand nutrients
Only nutritional source for brainOnly nutritional source for brain
metabolic activity is glucosemetabolic activity is glucose
Capillaries in the brain are much lessCapillaries in the brain are much less
leaky than other capillaries in the bodyleaky than other capillaries in the body
and form a blood brain barrierand form a blood brain barrier
7.05 Describe the function of CSF.7.05 Describe the function of CSF.
Mechanical ProtectionMechanical Protection
– Serves as a shock absorbing mediumServes as a shock absorbing medium
– Buoys the brain so it literally floats withinBuoys the brain so it literally floats within
the cranial cavitythe cranial cavity
Chemical ProtectionChemical Protection
– Provides an optimal chemical environmentProvides an optimal chemical environment
for neural signalingfor neural signaling
CirculationCirculation
– Acts as a medium for exchange of nutrientsActs as a medium for exchange of nutrients
and waste products between the blood andand waste products between the blood and
nervous tissuenervous tissue
7.05 Ventricles of the Brain7.05 Ventricles of the Brain
7.057.05
FlowFlow
ofof
Cerebro-Cerebro-
SpinalSpinal
FluidFluid
(CSF)(CSF)
7.057.05
FlowFlow
ofof
Cerebro-Cerebro-
SpinalSpinal
FluidFluid
HydrocephalusHydrocephalus
Blocked Cerebral AqueductBlocked Cerebral Aqueduct
7.06 Identify the structures responsible for7.06 Identify the structures responsible for
the maintenance and protection of thethe maintenance and protection of the
central nervous system.central nervous system.
Protected by the cranial bones and the cranial meningesProtected by the cranial bones and the cranial meninges
– Dura MaterDura Mater - outer layer- outer layer
– ArachnoidArachnoid - middle layer- middle layer
– Pia MaterPia Mater - inner layer- inner layer
Also protected byAlso protected by cerebrospinal fluid (CSF)cerebrospinal fluid (CSF)
– fluid that nourishes and protects the brain and spinal cordfluid that nourishes and protects the brain and spinal cord
– continuously circulates through the subarachnoid spacecontinuously circulates through the subarachnoid space
around the brain and throughout the cavities within thearound the brain and throughout the cavities within the
brainbrain
7.06 Meninges7.06 Meninges
Connective tissue covering foundConnective tissue covering found
around the brain and spinal cordaround the brain and spinal cord
Three layered membraneThree layered membrane
– Dura Mater - outer most layerDura Mater - outer most layer
dense irregular connective tissuedense irregular connective tissue
– Arachnoid - middle layerArachnoid - middle layer
spider web arrangement of collagen fibersspider web arrangement of collagen fibers
– Pia Mater - inner most meningesPia Mater - inner most meninges
very delicate layer of thin tissuevery delicate layer of thin tissue
7.06 Meninges of the Brain7.06 Meninges of the Brain
7.067.06
MeningesMeninges
of theof the
Spinal CordSpinal Cord
Dura MaterDura Mater
ArachnoidArachnoid
-Subarachnoid Space-Subarachnoid Space
Pia MaterPia Mater
The BRAINThe BRAIN
7.07 Identify the four principle7.07 Identify the four principle
parts of the brain.parts of the brain.
cerebrum, cerebellum, brain stem,cerebrum, cerebellum, brain stem,
diencephalondiencephalon
One of the largest organs in the bodyOne of the largest organs in the body
Controls all mental functionsControls all mental functions
Component of the CNSComponent of the CNS
Composed of over 100 billion neuronsComposed of over 100 billion neurons
Comprises 2-3% of body weightComprises 2-3% of body weight
Utilizes over 20% of body’s energyUtilizes over 20% of body’s energy
CEREBRUMCEREBRUM - occupies most of the- occupies most of the
cranium and is divided into right and leftcranium and is divided into right and left
halves called hemisphereshalves called hemispheres
CEREBELLUMCEREBELLUM - the posterior-inferior- the posterior-inferior
portion of the brainportion of the brain
BRAIN STEMBRAIN STEM - consists of the medulla- consists of the medulla
oblongata, thoblongata, thee pons, and the midbrainpons, and the midbrain
– it is continuous with the spinal cordit is continuous with the spinal cord
DIENCEPHALONDIENCEPHALON - located above the- located above the
brainstem, composed primarily of the:brainstem, composed primarily of the:
– ThalamusThalamus -- HypothalamusHypothalamus
The BrainThe Brain
7.08 Describe the functions of7.08 Describe the functions of
the three structures of thethe three structures of the
brain stem.brain stem.
The most inferior portion of the brainThe most inferior portion of the brain
Connects the brain to the spinal cordConnects the brain to the spinal cord
Composed of Three AreasComposed of Three Areas
– The Medulla OblongataThe Medulla Oblongata
– The PonsThe Pons
– The MidbrainThe Midbrain
7.08 The Medulla Oblongata7.08 The Medulla Oblongata
Most inferior portion of the brain stemMost inferior portion of the brain stem
Connects the brain stem to the spinalConnects the brain stem to the spinal
cordcord
Respiratory Center ***Respiratory Center ***
– Adjusts rhythm and depth of breathingAdjusts rhythm and depth of breathing
Cardiovascular Center ***Cardiovascular Center ***
– Regulates heart rate and contraction forceRegulates heart rate and contraction force
– Influences vasoconstriction andInfluences vasoconstriction and
vasodilationvasodilation
Also controls coughing, vomiting,Also controls coughing, vomiting,
swallowing, and hiccuppingswallowing, and hiccupping
The Medulla OblongataThe Medulla Oblongata
The Medulla OblongataThe Medulla Oblongata
7.08 The Pons7.08 The Pons
Lies superior to the medulla oblongataLies superior to the medulla oblongata
Together with the respiratory center inTogether with the respiratory center in
the medulla helps control respirationthe medulla helps control respiration
The PonsThe Pons
7.08 The Midbrain7.08 The Midbrain
Superior to the ponsSuperior to the pons
Connects the brain stem to theConnects the brain stem to the
diencephalondiencephalon
The MidbrainThe Midbrain
Pons and MidbrainPons and Midbrain
7.09 Describe the structures and7.09 Describe the structures and
functions of the diencephalon.functions of the diencephalon.
Area of the brain containing the:Area of the brain containing the:
– ThalamusThalamus
– HypothalamusHypothalamus
7.09 The Thalamus7.09 The Thalamus
Oval structure that makes up 80% of theOval structure that makes up 80% of the
diencephalondiencephalon
Comprised of a pair of oval massesComprised of a pair of oval masses
(mostly gray matter)(mostly gray matter)
PrinciplePrinciple relay stationrelay station between thebetween the
various sections of the brainvarious sections of the brain
The ThalamusThe Thalamus
7.09 The Hypothalamus7.09 The Hypothalamus
A small portion of the diencephalonA small portion of the diencephalon
located below the thalamuslocated below the thalamus
One of the main regulators ofOne of the main regulators of
homeostasis in the bodyhomeostasis in the body
Lacks a blood brain barrierLacks a blood brain barrier
Partially protected by the sella turcicaPartially protected by the sella turcica
of the sphenoid boneof the sphenoid bone
7.09 Functions of the7.09 Functions of the
HypothalamusHypothalamus
Coordinates Nervous System andCoordinates Nervous System and
Endocrine System activities to maintainEndocrine System activities to maintain
HomeostasisHomeostasis
– Thirst, Hunger, SatietyThirst, Hunger, Satiety
– Sleep Patterns and Waking StatesSleep Patterns and Waking States
– Sex Drive, Maturation, Aggression, andSex Drive, Maturation, Aggression, and
RageRage
– influences movement of food through theinfluences movement of food through the
Gastrointestinal TractGastrointestinal Tract
– production and secretion of hormones Thatproduction and secretion of hormones That
control other Endocrine Glandscontrol other Endocrine Glands
The HypothalamusThe Hypothalamus
HypothalamusHypothalamus
7.10 Describe the locations and functions7.10 Describe the locations and functions
of theof the four lobesfour lobes of the cerebrum.of the cerebrum.
Largest division of the brainLargest division of the brain
Occupies most of the craniumOccupies most of the cranium
Accounts for 85% of brain massAccounts for 85% of brain mass
Divided into right and left hemispheresDivided into right and left hemispheres
– Longitudinal FissureLongitudinal Fissure
– Corpus CallosumCorpus Callosum
Cerebral cortex - the outer surface areaCerebral cortex - the outer surface area
of the cerebrumof the cerebrum
– Composed mainly of gray matterComposed mainly of gray matter
– Contains billions of neuronsContains billions of neurons
The CerebrumThe Cerebrum
7.10 Describe the locations and7.10 Describe the locations and
functions of the four lobes of thefunctions of the four lobes of the
cerebrum.cerebrum.
Named after the bones that cover themNamed after the bones that cover them
– Frontal LobeFrontal Lobe
– Parietal LobeParietal Lobe
– Temporal LobeTemporal Lobe
– Occipital LobeOccipital Lobe
7.10 Frontal Lobe7.10 Frontal Lobe
Motor AreasMotor Areas
– Controls movement of voluntary skeletalControls movement of voluntary skeletal
musclesmuscles
Association AreasAssociation Areas
– Carry on high level intellectual processingCarry on high level intellectual processing
Problem SolvingProblem Solving - Reasoning- Reasoning - Planning- Planning
ConcentrationConcentration - Memory- Memory - Behavior- Behavior
EmotionsEmotions - Expressions- Expressions
7.10 Parietal Lobe7.10 Parietal Lobe
Sensory AreasSensory Areas
– Interprets sensations such as:Interprets sensations such as:
– touch - pressure - pain on the surface of thetouch - pressure - pain on the surface of the
skinskin
Association AreasAssociation Areas
– Understanding of speechUnderstanding of speech
– Using words to express thoughts andUsing words to express thoughts and
feelingsfeelings
7.10 Temporal Lobe7.10 Temporal Lobe
Sensory AreasSensory Areas
– Hearing and balanceHearing and balance
Association AreasAssociation Areas
– Interpret sensory experiencesInterpret sensory experiences
– Memory of visual scenes - music - smellsMemory of visual scenes - music - smells
and other complex sensory patternsand other complex sensory patterns
7.10 Occipital Lobe7.10 Occipital Lobe
Sensory AreasSensory Areas
– Visual processing and interpretationVisual processing and interpretation
Association AreasAssociation Areas
– Combines visual images with sensoryCombines visual images with sensory
experienceexperience
7.11 Explain the major7.11 Explain the major
functions of the cerebellum.functions of the cerebellum.
Second largest portion of the brainSecond largest portion of the brain
Occupies the inferior and posteriorOccupies the inferior and posterior
aspects of the cranial cavityaspects of the cranial cavity
Processes sensory informationProcesses sensory information
– BalanceBalance - Coordination- Coordination
– Maintains postural equilibriumMaintains postural equilibrium
The CerebellumThe Cerebellum
Cerebellum and BrainstemCerebellum and Brainstem
7.11 Cerebellar Test7.11 Cerebellar Test
Finger to Finger TestFinger to Finger Test
Finger to Nose TestFinger to Nose Test
Holme’s Sign (overreaction)Holme’s Sign (overreaction)
Romberg’s Test (Eyes Closed)Romberg’s Test (Eyes Closed)
7.12 Sequence the major events7.12 Sequence the major events
when the nerve impulsewhen the nerve impulse
(action potential) is initiated(action potential) is initiated
and transmitted through a neuron.and transmitted through a neuron.
The transmission of nerveThe transmission of nerve
(electrical) impulses from(electrical) impulses from
nervous tissue to othernervous tissue to other
nervous tissue, organs,nervous tissue, organs,
glands, and muscles.glands, and muscles.
7.12 Neuron Membrane Potential7.12 Neuron Membrane Potential
7.12 Neuron Action Potential7.12 Neuron Action Potential
7.12 Transmission of Nerve7.12 Transmission of Nerve
ImpulsesImpulses
An electrical event due to movement ofAn electrical event due to movement of
ions across a membraneions across a membrane
Also called an action potentialAlso called an action potential
– Lasts about 1 msec (1/1000 of a second)Lasts about 1 msec (1/1000 of a second)
– Dependent upon diameter of the axonDependent upon diameter of the axon
A-(thick myelin/fast), B-(thin myelin/moderate),A-(thick myelin/fast), B-(thin myelin/moderate),
C-(unmyelin/slow) fibersC-(unmyelin/slow) fibers
larger diameter axons - 0.4 msec (1/2500 sec)larger diameter axons - 0.4 msec (1/2500 sec)
– 2500 impulses per second2500 impulses per second
smaller diameter axons - 4 msec (1/250 sec)smaller diameter axons - 4 msec (1/250 sec)
– 250 impulses per second250 impulses per second
7.12 All or None Principle7.12 All or None Principle
If depolarization reaches a threshold, anIf depolarization reaches a threshold, an
action potential (impulse) is conductedaction potential (impulse) is conducted
Each action potential (impulse) isEach action potential (impulse) is
conducted at maximumconducted at maximum
strength unless there arestrength unless there are
toxic materials withintoxic materials within
the cell or the membranethe cell or the membrane
has been disruptedhas been disrupted
7.12 Neuron Impulse7.12 Neuron Impulse
7.12 Transmission of Nerve7.12 Transmission of Nerve
Impulses at SynapsesImpulses at Synapses
Most nervous conduction is fromMost nervous conduction is from
neuron to neuron (interneurons - 90%)neuron to neuron (interneurons - 90%)
Types of SynapsesTypes of Synapses
– Axon to dendriteAxon to dendrite
– Axon to somaAxon to soma
– Axon to axonAxon to axon
Two ways to transmit impulses across aTwo ways to transmit impulses across a
synapsesynapse
– Electrical SynapsesElectrical Synapses
– Chemical SynapsesChemical Synapses
7.127.12
NeuronNeuron
ActionAction
PotentialPotential
7.12 Types of Impulse Conduction7.12 Types of Impulse Conduction
Continuous ConductionContinuous Conduction - step by step- step by step
depolarization of each sequential,depolarization of each sequential,
adjacent area of of the nerve celladjacent area of of the nerve cell
membranemembrane
– typical of unmyelinated nerve fiberstypical of unmyelinated nerve fibers
– type of action potential in muscle fiberstype of action potential in muscle fibers
Saltatory ConductionSaltatory Conduction - the jumping of- the jumping of
an action potential across specializedan action potential across specialized
neurofibril nodes along the axonneurofibril nodes along the axon
– Nodes of RanvierNodes of Ranvier
7.12 Nerve Conduction7.12 Nerve Conduction
7.13 Explain the role of each of7.13 Explain the role of each of
the components of a reflex arc.the components of a reflex arc.
((reflexreflex,, reflex arc:reflex arc: receptorreceptor,,
sensory neuronsensory neuron,, associationassociation
[interneuron] neuron[interneuron] neuron,,
motor neuronmotor neuron,, effectoreffector))
7.13 The Reflex Arc:7.13 The Reflex Arc: receptor, sensoryreceptor, sensory
neuron, association [interneuron] neuron,neuron, association [interneuron] neuron,
motor neuron, effectormotor neuron, effector
A response by the body involving onlyA response by the body involving only
the body segment being affected andthe body segment being affected and
the spinal cordthe spinal cord
– Brain does not have to be involvedBrain does not have to be involved
Receptor - the distal end of a sensoryReceptor - the distal end of a sensory
neuron (dendrite)neuron (dendrite)
– Responds to a specific stimulusResponds to a specific stimulus
a change in internal or external environmenta change in internal or external environment
– Triggers a nerve impulseTriggers a nerve impulse
Sensory Neuron - the neuron located inSensory Neuron - the neuron located in
the gray matter of the spinal cordthe gray matter of the spinal cord
– conducts impulses from the receptor to theconducts impulses from the receptor to the
spinal cordspinal cord
Integrating Center - a region within theIntegrating Center - a region within the
CNS (spinal cord or brain) thatCNS (spinal cord or brain) that
interprets the information from theinterprets the information from the
sensory neuron and initiates ansensory neuron and initiates an
appropriate responseappropriate response
Motor Neurons - the neurons arisingMotor Neurons - the neurons arising
from the integrating center that relay afrom the integrating center that relay a
nerve impulse to the part of the bodynerve impulse to the part of the body
that will respond to the stimulusthat will respond to the stimulus
Effector - the part of the body thatEffector - the part of the body that
responds to the motor nerve impulseresponds to the motor nerve impulse
(usually a muscle or a gland)(usually a muscle or a gland)
– Effector - skeletal muscle - somatic reflexEffector - skeletal muscle - somatic reflex
– Effector - cardiac, smooth muscle, or glandEffector - cardiac, smooth muscle, or gland
-visceral reflex-visceral reflex
7.13 The Peripheral7.13 The Peripheral
Nervous System (PNS)Nervous System (PNS)
Connects sensory receptors, muscles,Connects sensory receptors, muscles,
and glands in the peripheral parts of theand glands in the peripheral parts of the
body to the central nervous systembody to the central nervous system
Consists of cranial and spinal nervesConsists of cranial and spinal nerves
Afferent Neurons (Sensory)Afferent Neurons (Sensory)
– conduct nerve impulses from sensoryconduct nerve impulses from sensory
receptors toward the CNSreceptors toward the CNS
Efferent Neurons (Motor)Efferent Neurons (Motor)
– conduct nerve impulses fromconduct nerve impulses from
the CNS to muscles and glandsthe CNS to muscles and glands
CNSCNS
PNSPNS
7.13 The Reflex Arc7.13 The Reflex Arc
7.13 Reflex arc (Reflexes).7.13 Reflex arc (Reflexes).
Fast, predictable, automatic responsesFast, predictable, automatic responses
to changes in the environment that helpto changes in the environment that help
maintain homeostasismaintain homeostasis
Somatic Reflexes - involve skeletalSomatic Reflexes - involve skeletal
musclesmuscles
Visceral (Autonomic) Reflexes - involveVisceral (Autonomic) Reflexes - involve
responses of smooth muscles, the heart,responses of smooth muscles, the heart,
and glandsand glands
Involve the spinal nervesInvolve the spinal nerves
7.13 Reflex Arc Examples7.13 Reflex Arc Examples
Stretch Reflex - results in theStretch Reflex - results in the
contraction of a muscle if it has beencontraction of a muscle if it has been
stretched suddenlystretched suddenly
Tendon Reflex - results in theTendon Reflex - results in the
contraction of a muscle when a tendoncontraction of a muscle when a tendon
is stretched suddenlyis stretched suddenly
Flexor (Withdrawal) Reflex - suddenFlexor (Withdrawal) Reflex - sudden
contraction and removal of a bodycontraction and removal of a body
segment as a result of a pain stimulussegment as a result of a pain stimulus
7.13 Tendon Reflex7.13 Tendon Reflex
7.137.13
WithdrawalWithdrawal
ReflexReflex
also calledalso called
FlexorFlexor
/Withdrawal/Withdrawal
ReflexReflex
07.14 Identify the following07.14 Identify the following
diseases or disorders of thediseases or disorders of the
nervous system.nervous system.
(ALS, Alzheimer’s, bacterial(ALS, Alzheimer’s, bacterial
meningitis, cerebral palsy,meningitis, cerebral palsy,
epilepsy, multipleepilepsy, multiple
sclerosis, Parkinson’s,sclerosis, Parkinson’s,
Guillain-Barre syndrome)Guillain-Barre syndrome)
7.14 Amyotrophic Lateral7.14 Amyotrophic Lateral
Sclerosis (ALS)Sclerosis (ALS)
Also known as Lou Gehrig’s DiseaseAlso known as Lou Gehrig’s Disease
A relatively rare neurological disorderA relatively rare neurological disorder
A syndrome marked by muscular weaknessA syndrome marked by muscular weakness
and atrophy with spasticity and hyperflexionand atrophy with spasticity and hyperflexion
due to degeneration of the motor neurons ofdue to degeneration of the motor neurons of
the spinal cord, medulla, and cortexthe spinal cord, medulla, and cortex
A degenerative diseaseA degenerative disease
No known cureNo known cure
7.14 Alzheimer’s Disease (AD)7.14 Alzheimer’s Disease (AD)
Disabling neurological disorder thatDisabling neurological disorder that
effects about 11% of the populationeffects about 11% of the population
Fourth leading cause of brain deathFourth leading cause of brain death
among the elderlyamong the elderly
A chronic, organic, mental disorder, aA chronic, organic, mental disorder, a
form of pre-senile dementia due toform of pre-senile dementia due to
atrophy of neurons of the frontal andatrophy of neurons of the frontal and
occipital lobesoccipital lobes
AD patients usually die fromAD patients usually die from
complications due to being bedriddencomplications due to being bedridden
7.14 Bacterial Meningitis7.14 Bacterial Meningitis
Infection of the meninges by theInfection of the meninges by the
bacterium Haemophilus Influenzaebacterium Haemophilus Influenzae
Usually affects children under age 5Usually affects children under age 5
Symptoms include severe headachesSymptoms include severe headaches
and feverand fever
Can lead to brain damage and evenCan lead to brain damage and even
death if not treateddeath if not treated
Brudzinki’s SignBrudzinki’s Sign
7.14 Cerebral Palsy (CP)7.14 Cerebral Palsy (CP)
A group of motor disorders due to lossA group of motor disorders due to loss
of muscle controlof muscle control
Caused by damage to the motor areasCaused by damage to the motor areas
of the brain during fetal development,of the brain during fetal development,
birth, or infancybirth, or infancy
About 70% of CP individuals areAbout 70% of CP individuals are
somewhat mentally retarded due to thesomewhat mentally retarded due to the
inability to hear well or speak fluentlyinability to hear well or speak fluently
Not a progressive disease but theNot a progressive disease but the
symptoms are irreversiblesymptoms are irreversible
7.14 Epilepsy7.14 Epilepsy
Short, recurrent, periodic, attacks ofShort, recurrent, periodic, attacks of
motor, sensory, or psychologicalmotor, sensory, or psychological
malfunctionmalfunction
Characterized by seizures which canCharacterized by seizures which can
result in involuntary skeletal muscleresult in involuntary skeletal muscle
contraction, loss of muscle control,contraction, loss of muscle control,
inability to sense light, noise, and smell,inability to sense light, noise, and smell,
and loss of consciousnessand loss of consciousness
Most epileptic seizures are idiopathicMost epileptic seizures are idiopathic
7.14 Multiple Sclerosis (MS)7.14 Multiple Sclerosis (MS)
Demyelinating disease of the CNSDemyelinating disease of the CNS
The sheaths deteriorates toThe sheaths deteriorates to sclerosesscleroses
– hardened scars or plaqueshardened scars or plaques
““short circuits” nerve transmissionshort circuits” nerve transmission
Cause is unknownCause is unknown
– May be a type of an autoimmune diseaseMay be a type of an autoimmune disease
No known cureNo known cure
Progressive loss of function withProgressive loss of function with
intermittent periods of remissionintermittent periods of remission
7.14 Guillain-Barre syndrome7.14 Guillain-Barre syndrome
Demyelinating disease of the PNSDemyelinating disease of the PNS
Caused by an Autoimmune diseaseCaused by an Autoimmune disease
Signs and symptomsSigns and symptoms
– muscle weakness in legs and difficult breathingmuscle weakness in legs and difficult breathing
60% recover completely within a year.60% recover completely within a year.
5-10% recover with severe disability5-10% recover with severe disability
low percent death ratelow percent death rate
7.14 Parkinson’s Disease (PD)7.14 Parkinson’s Disease (PD)
A progressive disorder of the CNS thatA progressive disorder of the CNS that
usually affects individuals over 60usually affects individuals over 60
Cause is unknown but a toxicCause is unknown but a toxic
environmental factor is suspectedenvironmental factor is suspected
Chemical basis of the disease appears toChemical basis of the disease appears to
be to little dopamine and too much Achbe to little dopamine and too much Ach
Treatment includes increasing levels ofTreatment includes increasing levels of
dopamine and decreasing Achdopamine and decreasing Ach
– Difficult because dopamine does not crossDifficult because dopamine does not cross
the blood brain barrierthe blood brain barrier
A chronic nervous diseaseA chronic nervous disease
characterized by a fine, slowlycharacterized by a fine, slowly
spreading tremor, muscle weaknessspreading tremor, muscle weakness
and rigidity, and a peculiar gaitand rigidity, and a peculiar gait
Other causes may include brain damageOther causes may include brain damage
at birth, metabolic disturbances,at birth, metabolic disturbances,
infections, toxins, vascularinfections, toxins, vascular
disturbances, head injuries, and tumorsdisturbances, head injuries, and tumors
and abscesses of the brainand abscesses of the brain
Usually can be controlled with drugUsually can be controlled with drug
therapytherapy
– GABA - gamma aminobutyric acidGABA - gamma aminobutyric acid
Symptoms include muscle tremor,Symptoms include muscle tremor,
muscle rigidity, bradykinesia,muscle rigidity, bradykinesia,
hypokinesia or dyskinesia, speech andhypokinesia or dyskinesia, speech and
walking impairmentwalking impairment
Attempting to transplant fetal nervousAttempting to transplant fetal nervous
tissue into the damaged area of thetissue into the damaged area of the
brain of some Parkinson’s Diseasebrain of some Parkinson’s Disease
patientspatients
7.14 Cerebral Vascular7.14 Cerebral Vascular
AccidentAccident
(CVA) - Stroke(CVA) - Stroke
The most common brain disorderThe most common brain disorder
Characterized by slurred speech, loss ofCharacterized by slurred speech, loss of
or blurred vision, dizziness, weakness,or blurred vision, dizziness, weakness,
paralysis of a limb or hemiplegia, coma,paralysis of a limb or hemiplegia, coma,
and deathand death
Ischemic CVA - due to lack of bloodIschemic CVA - due to lack of blood
supply to a particular area of the brainsupply to a particular area of the brain
Hemorrhagic CVA - due to the ruptureHemorrhagic CVA - due to the rupture
of a blood vessel in the brainof a blood vessel in the brain
7.14 Risk Factors for Stroke7.14 Risk Factors for Stroke
hypertensionhypertension
heart diseaseheart disease
smokingsmoking
diabetesdiabetes
atherosclerosisatherosclerosis
hyperlipidemiahyperlipidemia
obesityobesity
excessive alcohol intakeexcessive alcohol intake
SensationsSensations
andand
Special SensesSpecial Senses
SensesSenses
Specialized structures of theSpecialized structures of the
nervous system which providenervous system which provide
information about theinformation about the
environment in which we live toenvironment in which we live to
help maintain homeostasishelp maintain homeostasis
Functions ofFunctions of
Special SensesSpecial Senses
Sensory - monitoring the body and theSensory - monitoring the body and the
external environment for changingexternal environment for changing
conditionsconditions
Sensory PathwaysSensory Pathways
All pathways begin with a receptor andAll pathways begin with a receptor and
the sensory information is transmittedthe sensory information is transmitted
to the CNSto the CNS
Always begins with a stimulusAlways begins with a stimulus
– change in the environmentchange in the environment
ReceptorsReceptors
Structures which provide feedbackStructures which provide feedback
about the environmentabout the environment
Are impulse specificAre impulse specific
– Only respond to one type of stimulusOnly respond to one type of stimulus
Many have sensory functionMany have sensory function
adaptationsadaptations
– May end as bare dendrites or be a complexMay end as bare dendrites or be a complex
organorgan
VisionVision
The most complex of the special sensesThe most complex of the special senses
– Over 70% of the sensory receptors in theOver 70% of the sensory receptors in the
body are photoreceptors for sightbody are photoreceptors for sight
Visual organs, the eyes are supportedVisual organs, the eyes are supported
by a number of accessory structuresby a number of accessory structures
and internal organsand internal organs
– Dependent upon photoreceptors in theDependent upon photoreceptors in the
eyeseyes
7.15 Describe the principle7.15 Describe the principle
anatomical structures of the eye.anatomical structures of the eye.
1.1. Accessory structuresAccessory structures:: eyelideyelid,,
conjunctivaconjunctiva,, lacrimal apparatuslacrimal apparatus,, extrinsicextrinsic
musclesmuscles..
2.2. Layers of the eyeballLayers of the eyeball:: fibrous tunicfibrous tunic
(sclera, cornea),(sclera, cornea), vascular tunicvascular tunic (choroid,(choroid,
ciliary body, iris, lens, pupil),ciliary body, iris, lens, pupil),
nervous tunicnervous tunic (retina).(retina).
The EyeThe Eye
7.15 Accessory Structures7.15 Accessory Structures
of the Eyeof the Eye
Eyelids - protects the anterior surfaceEyelids - protects the anterior surface
– Conjunctiva - the mucous membrane of the eyelidConjunctiva - the mucous membrane of the eyelid
– Helps moisten and lubricate the eyeballHelps moisten and lubricate the eyeball
Lacrimal Apparatus - secretes tearsLacrimal Apparatus - secretes tears
– lacrimal glandlacrimal gland - lacrimal sac- lacrimal sac
– lacrimal canalslacrimal canals - nasolacrimal duct- nasolacrimal duct
– moistens and lubricates the eyeballmoistens and lubricates the eyeball
– fights against infection (enzymes in tears)fights against infection (enzymes in tears)
Extrinsic Muscles of the Eyeball (6)Extrinsic Muscles of the Eyeball (6)
– skeletal muscles that move the eyeballskeletal muscles that move the eyeball
7.15 Six Extrinsic Eye Muscles7.15 Six Extrinsic Eye Muscles
Lateral Rectus (LR)Lateral Rectus (LR)
Medial Rectus (MR)Medial Rectus (MR)
Inferior Rectus (IR)Inferior Rectus (IR)
Superior Rectus (SR)Superior Rectus (SR)
Superior Oblique (SO)Superior Oblique (SO)
Inferior Oblique (IO)Inferior Oblique (IO)
H in space tests three cranialH in space tests three cranial
nerves. SO4,LR6, all else 3.nerves. SO4,LR6, all else 3.
Trochlear-4Trochlear-4
Abducens-6Abducens-6
Oculomotor-3Oculomotor-3
7.157.15
AccessoryAccessory
StructuresStructures
of theof the
EyeEye
7.15 Structure of the Eye7.15 Structure of the Eye
The wall consists of three layers ofThe wall consists of three layers of
tissue or tunicstissue or tunics
Fibrous Tunic - outer layerFibrous Tunic - outer layer
Vascular Tunic - middle layerVascular Tunic - middle layer
Nervous Tunic - inner layerNervous Tunic - inner layer
7.15 Fibrous Tunic7.15 Fibrous Tunic
Thick, outermost layer of the eyeballThick, outermost layer of the eyeball
Sclera - the posterior “white” portionSclera - the posterior “white” portion
– Forms most of the fibrous tunicForms most of the fibrous tunic
– The “whites” of the eyeThe “whites” of the eye
Cornea - the anterior transparentCornea - the anterior transparent
portion of the fibrous tunicportion of the fibrous tunic
– Bulges outward slightlyBulges outward slightly
Fibrous TunicFibrous Tunic
7.15 Vascular Tunic7.15 Vascular Tunic
Extremely vascularExtremely vascular
Supplies blood to numerous structuresSupplies blood to numerous structures
of the eyeof the eye
– ChoroidChoroid - Ciliary Body- Ciliary Body
– IrisIris - Lens- Lens
– PupilPupil
Vascular TunicVascular Tunic
7.15 Vascular Tunic7.15 Vascular Tunic
Choroid - posterior, thin portion of theChoroid - posterior, thin portion of the
vascular tunicvascular tunic
– A thin, dark brown membrane that lines most ofA thin, dark brown membrane that lines most of
the internal surface of the sclerathe internal surface of the sclera
Ciliary Body - anterior, thick portion of theCiliary Body - anterior, thick portion of the
vascular tunicvascular tunic
– Thickest part of the vascular tunicThickest part of the vascular tunic
– Consists of smooth muscle fibersConsists of smooth muscle fibers
– Attaches to the lens by ligamentsAttaches to the lens by ligaments
– Changes the thickness and shape of the lens.Changes the thickness and shape of the lens.
Ciliary BodyCiliary Body
7.15 Vascular Tunic7.15 Vascular Tunic
Iris - anterior, colored portion of the VascularIris - anterior, colored portion of the Vascular
TunicTunic
– contraction of it’s smooth muscle accounts forcontraction of it’s smooth muscle accounts for
dilation or constriction of the Pupils (openings todilation or constriction of the Pupils (openings to
the inner cavities of the eyes)the inner cavities of the eyes)
Lens - special tissue which focuses and directsLens - special tissue which focuses and directs
light entering the eyelight entering the eye
– suspended by the Ciliary Bodysuspended by the Ciliary Body
– located behind the Irislocated behind the Iris
– alteration of the shape of the lens to accommodatealteration of the shape of the lens to accommodate
for near or far vision focusing (Accommodation)for near or far vision focusing (Accommodation)
The LensThe Lens
Iris – Pupil DiameterIris – Pupil Diameter
7.15 Nervous Tunic7.15 Nervous Tunic
The inner layer of the eyeThe inner layer of the eye
Retina - a thin fragile layer of neurons thatRetina - a thin fragile layer of neurons that
forms the inner lining of the eyeball’sforms the inner lining of the eyeball’s
posterior wallposterior wall
– Lines the posterior cavity and contains theLines the posterior cavity and contains the
photoreceptor cells (rods and cones), bipolarphotoreceptor cells (rods and cones), bipolar
neurons, and ganglion cellsneurons, and ganglion cells
Optic Nerve - axons and ganglion cellsOptic Nerve - axons and ganglion cells
– Transmits images to the occipital lobe of the brainTransmits images to the occipital lobe of the brain
for interpretation of what we seefor interpretation of what we see
Nervous TunicNervous Tunic
7.15 Rods and Cones7.15 Rods and Cones
Rods - elongated cylindrical dendritesRods - elongated cylindrical dendrites
that are sensitive to varying lightthat are sensitive to varying light
conditionsconditions
– Allows us to see under varying lightAllows us to see under varying light
intensities (night vision)intensities (night vision)
Cones - dendrites with tapered endsCones - dendrites with tapered ends
– Color sensitiveColor sensitive
– Determines the “sharpness” of visionDetermines the “sharpness” of vision
7.157.15
RodsRods
andand
ConesCones
Rods and ConesRods and Cones
7.15 Other Structures of the7.15 Other Structures of the
Nervous TunicNervous Tunic
Optic Disc - blind spot where the opticOptic Disc - blind spot where the optic
nerve exits the retinanerve exits the retina
Fovea Centralis - an area of the retinaFovea Centralis - an area of the retina
containing many cone cellscontaining many cone cells
– the area of sharpest visionthe area of sharpest vision
RetinaRetina
Elements of Vision in the EyeElements of Vision in the Eye
Vision spectrum of the eyeVision spectrum of the eye
– only detect three colorsonly detect three colors
– RedRed - Green- Green - Blue- Blue
Aspects of vision of the eyeAspects of vision of the eye
– colorcolor
– motionmotion
– formform
– depthdepth
RefractionRefraction
the “bending” of light rays as it travelsthe “bending” of light rays as it travels
through the eyethrough the eye
the pathway of light as it travels through thethe pathway of light as it travels through the
eyeeye
influenced by:influenced by:
– shape of the lensshape of the lens
– shape and thickness of the corneashape and thickness of the cornea
– amount and consistency of the Aqueous andamount and consistency of the Aqueous and
Vitreous HumorVitreous Humor
RefractionRefraction
VisionVision
AbnormalitiesAbnormalities
Physiology of VisionPhysiology of Vision
Rods and cones convert light wavesRods and cones convert light waves
into a series of signals that results in theinto a series of signals that results in the
generation of an action potential in thegeneration of an action potential in the
ganglion cellsganglion cells
– Both rods and cones contain pigments thatBoth rods and cones contain pigments that
decompose when exposed to lightdecompose when exposed to light
– The decomposition of the pigments is whatThe decomposition of the pigments is what
generates the action potentialgenerates the action potential
Visual PathwaysVisual Pathways
From the rods and cones, the nervousFrom the rods and cones, the nervous
impulse is passed on to bipolar neurons andimpulse is passed on to bipolar neurons and
then on to ganglion cellsthen on to ganglion cells
Axons from the ganglion cells extend out ofAxons from the ganglion cells extend out of
the eye and converge to from the optic nervethe eye and converge to from the optic nerve
The optic nerves cross behind the eye at anThe optic nerves cross behind the eye at an
area known as the optic chiasmaarea known as the optic chiasma
The optic nerve terminates at the thalamusThe optic nerve terminates at the thalamus
Visual PathwaysVisual Pathways
Visual impulses from the thalamus areVisual impulses from the thalamus are
transmitted by other neurons to thetransmitted by other neurons to the
occipital lobe of the cerebral cortexoccipital lobe of the cerebral cortex
where the impulses are interpreted aswhere the impulses are interpreted as
the sense of sight.the sense of sight.
Visual PathwaysVisual Pathways
7.16 Describe the principle7.16 Describe the principle
anatomical structures of the ear.anatomical structures of the ear.
Outer EarOuter Ear -- auricle, auditory canal.auricle, auditory canal.
Middle EarMiddle Ear - tympanic cavity, tympanic- tympanic cavity, tympanic
membrane, auditory (Eustachian) tube,membrane, auditory (Eustachian) tube,
auditory ossicles (malleus, incus, stapes).auditory ossicles (malleus, incus, stapes).
Inner EarInner Ear - bony labyrinth, membranous- bony labyrinth, membranous
labyrinth, semicircular canals, vestibule,labyrinth, semicircular canals, vestibule,
cochlea, Organ of Corti.cochlea, Organ of Corti.
The EarThe Ear
7.16 Outer Ear7.16 Outer Ear
Direct sound waves toward theDirect sound waves toward the
eardrumeardrum
Auricle - the outer appendageAuricle - the outer appendage
Auditory Canal - a tube that extendsAuditory Canal - a tube that extends
into the temporal boneinto the temporal bone
The Outer EarThe Outer Ear
Middle EarMiddle Ear
An air-filled space within the temporalAn air-filled space within the temporal
bonebone
Tympanic Cavity - contains theTympanic Cavity - contains the
auditory ossiclesauditory ossicles
– Smallest bones in the bodySmallest bones in the body
Malleus (hammer)Malleus (hammer)
Incus (anvil)Incus (anvil)
Stapes (stirrup)Stapes (stirrup)
7.16 Middle Ear7.16 Middle Ear
Auditory (Eustachian) Tube - a tubeAuditory (Eustachian) Tube - a tube
from the middle ear to the pharynxfrom the middle ear to the pharynx
– Allows for pressure equalization betweenAllows for pressure equalization between
the middle ear and the atmospherethe middle ear and the atmosphere
Tympanic Membrane (Eardrum) - thin,Tympanic Membrane (Eardrum) - thin,
semitransparent membrane separatingsemitransparent membrane separating
the outer and the middle earthe outer and the middle ear
– Vibrates in response to sound wavesVibrates in response to sound waves
striking itstriking it
– The vibrations are then transmitted to theThe vibrations are then transmitted to the
auditory ossiclesauditory ossicles
Middle Ear StructuresMiddle Ear Structures
The tympanic membrane and auditoryThe tympanic membrane and auditory
ossicles convert sound waves intoossicles convert sound waves into
mechanical movement within themechanical movement within the
middle ear and then transmit thatmiddle ear and then transmit that
motion to the “oval window”motion to the “oval window”
The oval window opens into theThe oval window opens into the
cochlea of the inner earcochlea of the inner ear
Within the inner ear the vibrations ofWithin the inner ear the vibrations of
the stapes causes the fluid within thethe stapes causes the fluid within the
inner ear to move stimulating theinner ear to move stimulating the
receptors for hearingreceptors for hearing
7.16 The Three Regions of7.16 The Three Regions of
the Inner Earthe Inner Ear
Formed by the canals of the bony labyrinthFormed by the canals of the bony labyrinth
and the series of sacs of the membranousand the series of sacs of the membranous
labyrinthlabyrinth
Involved in both the sense of hearing and theInvolved in both the sense of hearing and the
maintenance of balance and equilibriummaintenance of balance and equilibrium
CochleaCochlea
VestibuleVestibule
Semicircular CanalsSemicircular Canals
The Inner EarThe Inner Ear
Inner Ear StructuresInner Ear Structures
The Semicircular Canals - three loops that lieThe Semicircular Canals - three loops that lie
at right angles to each otherat right angles to each other
The Vestibule - the chamber between theThe Vestibule - the chamber between the
cochlea and the semicircular canalscochlea and the semicircular canals
– Both the semicircular canals and the vestibule areBoth the semicircular canals and the vestibule are
involved with maintaining balance or equilibriuminvolved with maintaining balance or equilibrium
The Cochlea - shape resembles a snail shellThe Cochlea - shape resembles a snail shell
– Contains the organs of hearing (Corti)Contains the organs of hearing (Corti)
Receptor cells that move in response to endolymphReceptor cells that move in response to endolymph
motionmotion
Releases neurotransmitters that stimulate nerve impulsesReleases neurotransmitters that stimulate nerve impulses
The CochleaThe Cochlea
Organ of CortiOrgan of Corti
Cross Section of CochleaCross Section of Cochlea
7.16 Inner Ear (Labyrinth)7.16 Inner Ear (Labyrinth)
Consists of a winding, complicated series ofConsists of a winding, complicated series of
passageways or canalspassageways or canals
Bony Labyrinth - a series of canals within theBony Labyrinth - a series of canals within the
temporal bonetemporal bone
– Contains perilymphContains perilymph
Membranous Labyrinth - an internal series ofMembranous Labyrinth - an internal series of
sacs and tubessacs and tubes
– Contains endolymphContains endolymph
– Conforms to the bony labyrinth shapeConforms to the bony labyrinth shape
– Also helps form the shape of the three regions ofAlso helps form the shape of the three regions of
the inner earthe inner ear
Vestibulocochlear NerveVestibulocochlear Nerve
Nerve PathwaysNerve Pathways
Sound waves cause the tympanic membraneSound waves cause the tympanic membrane
to vibrateto vibrate
The vibration of the tympanic membraneThe vibration of the tympanic membrane
causes the stapes to move back and forthcauses the stapes to move back and forth
Movement of the stapes back and forthMovement of the stapes back and forth
pushes the oval window in and outpushes the oval window in and out
producing waves in the perilymph of theproducing waves in the perilymph of the
inner earinner ear
Pressure waves in the perilymph pushPressure waves in the perilymph push
the vestibular membrane inwardthe vestibular membrane inward
increasing the pressure of theincreasing the pressure of the
endolymph within the cochlear ductendolymph within the cochlear duct
The hair cells in the Organ of CortiThe hair cells in the Organ of Corti
convert the motion of the endolymph toconvert the motion of the endolymph to
the release of neurotransmittersthe release of neurotransmitters
These neurotransmitters stimulate aThese neurotransmitters stimulate a
nerve impulse in a sensory branch ofnerve impulse in a sensory branch of
the Vestibulocochlear Nerve (CN #VIII)the Vestibulocochlear Nerve (CN #VIII)
The impulse is then transferred throughThe impulse is then transferred through
the midbrain and the thalamus andthe midbrain and the thalamus and
finally terminates in the temporal lobefinally terminates in the temporal lobe
of the cerebral cortex where the soundof the cerebral cortex where the sound
is interpretedis interpreted
Physiology of HearingPhysiology of Hearing
7.17 Identify the following7.17 Identify the following
diseases or disorders associateddiseases or disorders associated
with special senses:with special senses:
presbyopiapresbyopia,, myopiamyopia,, hyperopiahyperopia,, cataractscataracts,,
conjunctivitisconjunctivitis,, deafness (conductive,deafness (conductive,
Sensorineural)Sensorineural),, glaucomaglaucoma,, macularmacular
degenerationdegeneration,, middle ear infectionmiddle ear infection,,
strabismusstrabismus,, tinnitustinnitus,, vertigovertigo..
7.17 Ametropia7.17 Ametropia
(abnormal refracted light)(abnormal refracted light)
MyopiaMyopia - nearsightedness- nearsightedness
– Imaged focused in front of the retinaImaged focused in front of the retina
HyperopiaHyperopia - farsightedness- farsightedness
– Image focused in back of the retinaImage focused in back of the retina
PresbyopiaPresbyopia - a defect in vision in- a defect in vision in
advancing age involving loss ofadvancing age involving loss of
accommodation or recession of nearaccommodation or recession of near
point (results in farsightedness)point (results in farsightedness)
7.17 Cataracts7.17 Cataracts
Abnormal loss of transparency of theAbnormal loss of transparency of the
lenslens
Vision becomes blurry or cloudyVision becomes blurry or cloudy
Can be removed and have an artificialCan be removed and have an artificial
lens insertedlens inserted
Most often occurs to individuals overMost often occurs to individuals over
the age of 50. Exposure tothe age of 50. Exposure to
sunlight and smokingsunlight and smoking
increases the risk.increases the risk.
7.17 Pink Eye/Cross-eyed7.17 Pink Eye/Cross-eyed
Conjunctivitis - inflammation of theConjunctivitis - inflammation of the
conjunctiva, the mucous membrane thatconjunctiva, the mucous membrane that
lines the eyelid and is reflected to thelines the eyelid and is reflected to the
eyeball. Also known as “Pink Eye”eyeball. Also known as “Pink Eye”
Strabismus – “cross-eyed”Strabismus – “cross-eyed”
7.17 Glaucoma7.17 Glaucoma
A group of eye diseases characterized byA group of eye diseases characterized by
elevatedelevated intraocular pressureintraocular pressure in the eyein the eye
resulting in atrophy of the optic nerve whichresulting in atrophy of the optic nerve which
may lead to blindnessmay lead to blindness
Caused by an obstruction of the outflow ofCaused by an obstruction of the outflow of
the aqueous and vitreous humorthe aqueous and vitreous humor
Minor cases can be treated with eye dropsMinor cases can be treated with eye drops
More severe cases may require a surgicalMore severe cases may require a surgical
incision into the iris of the eyeincision into the iris of the eye
7.17 Macular Degeneration7.17 Macular Degeneration
The destruction or tearing away of the retinaThe destruction or tearing away of the retina
from the back of the eyefrom the back of the eye
Commonly occurs in the region of the retinaCommonly occurs in the region of the retina
known as the macula luteaknown as the macula lutea
Can be caused by:Can be caused by:
– Vascular diseases (diabetes)Vascular diseases (diabetes)
– Chronic increased pressure (glaucoma)Chronic increased pressure (glaucoma)
– Sudden blow or impact to the head or eyeSudden blow or impact to the head or eye
(Detached Retina)(Detached Retina)
7.17 Vertigo7.17 Vertigo
A condition of dizziness and spatialA condition of dizziness and spatial
disorientationdisorientation
In some individuals it is due to heightsIn some individuals it is due to heights
or fear of high placesor fear of high places
A spinning sensation that may result inA spinning sensation that may result in
loss of balance and equilibriumloss of balance and equilibrium
7.17 Tinnitus7.17 Tinnitus
Ringing or tinkling sounds orRinging or tinkling sounds or
sensations in the earsensations in the ear
7.17 Middle Ear Infection7.17 Middle Ear Infection
Infection of the tympanic membrane orInfection of the tympanic membrane or
other structures associated with theother structures associated with the
middle ear (Otitis Media)middle ear (Otitis Media)
7.17 Deafness7.17 Deafness
Loss of the ability to hearLoss of the ability to hear
Conductive DeafnessConductive Deafness: deafness: deafness
resulting from any condition thatresulting from any condition that
prevents sound waves from beingprevents sound waves from being
transmitted to the auditory receptorstransmitted to the auditory receptors
Sensorineural DeafnessSensorineural Deafness: deafness due to: deafness due to
defective function of the cochlea, organdefective function of the cochlea, organ
of Corti, or the auditory nerveof Corti, or the auditory nerve
Unit 7 nervous & special senses

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Unit 7 nervous & special senses

  • 1. The NERVOUS SystemThe NERVOUS System
  • 2. 7.01 The three broad functions of7.01 The three broad functions of the nervous system:the nervous system: SensorySensory – senses stimuli from both within the bodysenses stimuli from both within the body and from the external environmentand from the external environment IntegrativeIntegrative – analyzes, interprets, and stores informationanalyzes, interprets, and stores information about the stimuli it has receives from theabout the stimuli it has receives from the sensory portion of the nervous systemsensory portion of the nervous system MotorMotor – responds to stimuli by some type of actionresponds to stimuli by some type of action muscular contractionmuscular contraction glandular secretionglandular secretion
  • 3. 7.02 Describe the general organization of7.02 Describe the general organization of the nervous system.the nervous system. Central Nervous System (CNS)Central Nervous System (CNS) – BrainBrain – Spinal CordSpinal Cord Peripheral Nervous System (PNS)Peripheral Nervous System (PNS) – Spinal Nerves (31 pairs)Spinal Nerves (31 pairs) – Cranial Nerves (I-XII pairs)Cranial Nerves (I-XII pairs) – SubdivisionsSubdivisions Autonomic Nervous System (ANS) - InvolutaryAutonomic Nervous System (ANS) - Involutary – SympatheticSympathetic – ParasympatheticParasympathetic Somatic Nervous System - VoluntarySomatic Nervous System - Voluntary
  • 4. 7.02 The Central Nervous System7.02 The Central Nervous System (CNS)(CNS) Brain and Spinal CordBrain and Spinal Cord CNS FunctionCNS Function – Sorts incoming sensorySorts incoming sensory informationinformation – Generates thoughts andGenerates thoughts and emotionsemotions – Forms and stores memoriesForms and stores memories – Stimulates muscle contractionsStimulates muscle contractions – Stimulates glandular secretionsStimulates glandular secretions
  • 5. 7.02 Peripheral Nervous System7.02 Peripheral Nervous System (PNS)(PNS) Spinal and Cranial NervesSpinal and Cranial Nerves – Spinal Nerves (31 pairs)Spinal Nerves (31 pairs) – Cranial Nerves (I-XII pairs)Cranial Nerves (I-XII pairs) – SubdivisionsSubdivisions Autonomic Nervous System (ANS) - InvolutaryAutonomic Nervous System (ANS) - Involutary – SympatheticSympathetic – ParasympatheticParasympathetic Somatic Nervous System - VoluntarySomatic Nervous System - Voluntary CNSCNS PNSPNS
  • 6. GreenGreen is the PNSis the PNS CNSCNS
  • 7. 7.02 The Autonomic7.02 The Autonomic Nervous System (ANS)Nervous System (ANS) Contains sensory neurons mainly from theContains sensory neurons mainly from the viscera that convey information to theviscera that convey information to the CNSCNS Contains the efferent neurons that conductContains the efferent neurons that conduct impulses to smooth muscle, cardiacimpulses to smooth muscle, cardiac muscle, and glandsmuscle, and glands Unconscious controlUnconscious control Two divisions of the ANSTwo divisions of the ANS – Sympathetic Division - stimulatory effectSympathetic Division - stimulatory effect – Parasympathetic Division - inhibitory effectParasympathetic Division - inhibitory effect
  • 8. SympatheticSympathetic Stimulatory.Stimulatory. “Fight or Flight”“Fight or Flight” ParasympatheticParasympathetic Inhibitory.Inhibitory.
  • 9. 7.02 The Somatic Nervous System7.02 The Somatic Nervous System (SNS)(SNS) Made up of sensory neurons thatMade up of sensory neurons that convey information from the cutaneousconvey information from the cutaneous and special sense receptors in the head,and special sense receptors in the head, body wall, and extremities to the CNSbody wall, and extremities to the CNS Also contains the motor neurons fromAlso contains the motor neurons from the CNS that conduct impulses to thethe CNS that conduct impulses to the skeletal musclesskeletal muscles
  • 10. 7.03 List the functions and7.03 List the functions and structures of neurons.structures of neurons. The nerve cells responsible for theThe nerve cells responsible for the special functions of the nervous systemspecial functions of the nervous system – sensingsensing - remembering- remembering - thinking- thinking – controlling muscle activitycontrolling muscle activity – controlling glandular secretionscontrolling glandular secretions Synapse - the functional relay pointsSynapse - the functional relay points between two neurons or between abetween two neurons or between a neuron and an effector organneuron and an effector organ – Neuromuscular JunctionNeuromuscular Junction – Neuroglandular JunctionNeuroglandular Junction
  • 11. 7.03 List the functions and7.03 List the functions and structures of neurons.structures of neurons. Cell Body (Soma or Perikaryon)Cell Body (Soma or Perikaryon) – nucleus, cytoplasm, organelles of a neuronnucleus, cytoplasm, organelles of a neuron Dendrites - tapered, highly branchedDendrites - tapered, highly branched processes protruding from the cell bodyprocesses protruding from the cell body – usually very shortusually very short – AFFERENT FUNCTIONAFFERENT FUNCTION Axons - long, thin, cylindrical processAxons - long, thin, cylindrical process – usually myelinatedusually myelinated – EFFERENT FUNCTIONEFFERENT FUNCTION
  • 14. 7.03 List the functions and7.03 List the functions and structures ofstructures of neuroglialneuroglial cells:cells: Nervous system cells that support,Nervous system cells that support, nurture and protect the neuronsnurture and protect the neurons Types of Neuroglia found in theTypes of Neuroglia found in the CNSCNS – AstrocytesAstrocytes – OligodendrocytesOligodendrocytes – MicrogliaMicroglia – Ependymal CellsEpendymal Cells Types of Neuroglia found in theTypes of Neuroglia found in the PNSPNS – Neurolemmocytes (Schwann Cells)Neurolemmocytes (Schwann Cells) – Satellite CellsSatellite Cells
  • 15. 7.03 Astrocytes (Astroglia)7.03 Astrocytes (Astroglia) Star-shaped cells with many processesStar-shaped cells with many processes Forms the Blood Brain Barrier (BBB)Forms the Blood Brain Barrier (BBB) Forms the pia mater covering the brainForms the pia mater covering the brain and spinal cord.and spinal cord. Soaks up excess ions and toxinsSoaks up excess ions and toxins Participate in brain developmentParticipate in brain development Facilitates repair for CNS traumaFacilitates repair for CNS trauma
  • 17. 7.03 Microglia7.03 Microglia Small phagocytic cells that protect theSmall phagocytic cells that protect the central nervous system by engulfingcentral nervous system by engulfing and invading microbesand invading microbes Clears awayClears away debris fromdebris from dead cellsdead cells
  • 18. 7.03 Oligodendrocytes7.03 Oligodendrocytes (Oligodendroglia)(Oligodendroglia) Oligo- small or fewOligo- small or few Small glial cells with few processesSmall glial cells with few processes Form a supporting network around theForm a supporting network around the neurons by twining around neuronsneurons by twining around neurons and producing a lipid and proteinand producing a lipid and protein wrapping around the neuronswrapping around the neurons ((myelin sheathmyelin sheath))
  • 20. 7.03 Ependymal Cells7.03 Ependymal Cells Neuroglia cells lineNeuroglia cells line the brain ventriclesthe brain ventricles and the central canaland the central canal of the spinal cordof the spinal cord Form and circulateForm and circulate cerebral spinal fluidcerebral spinal fluid (CSF)(CSF)
  • 21. 7.03 Neuroglia of the PNS7.03 Neuroglia of the PNS (Schwann and Satellite cells)(Schwann and Satellite cells) Schwann CellsSchwann Cells - Neurolemmocytes- Neurolemmocytes – Cells responsible for producing the myelinCells responsible for producing the myelin sheaths around the PNS neuronssheaths around the PNS neurons Satellite CellsSatellite Cells – Similar to astrocytesSimilar to astrocytes – Structural supportStructural support – soaks up excess ionssoaks up excess ions and toxinsand toxins
  • 22. 7.03 Schwann Cell Myelination7.03 Schwann Cell Myelination
  • 24. 7.03 Myelination7.03 Myelination The process of developing or producingThe process of developing or producing a Myelin Sheatha Myelin Sheath Insulates the axon of a neuronInsulates the axon of a neuron Increases the speed of nerve impulseIncreases the speed of nerve impulse conductionconduction – CNS - oligodendrocytesCNS - oligodendrocytes – PNS - neurolemmocytes (Schwann Cells)PNS - neurolemmocytes (Schwann Cells) Guillain-Barre syndrome and MultipleGuillain-Barre syndrome and Multiple Sclerosis are involved the destruction ofSclerosis are involved the destruction of the myelin sheaths around the nervethe myelin sheaths around the nerve
  • 25. 7.04 Contrast white and gray7.04 Contrast white and gray matter of nervous tissue.matter of nervous tissue. White MatterWhite Matter - the aggregation of- the aggregation of myelinatedmyelinated processes from manyprocesses from many neuronsneurons – Visible upon freshly dissected brain orVisible upon freshly dissected brain or spinal tissuespinal tissue – White color is due to myelinationWhite color is due to myelination Gray MatterGray Matter -- unmyelinatedunmyelinated nerve cellnerve cell bodies, axons, dendrites, ganglia, andbodies, axons, dendrites, ganglia, and axon terminalsaxon terminals – Appears gray because of lack of myelinAppears gray because of lack of myelin
  • 26. 7.04 Gray and White Matter7.04 Gray and White Matter
  • 27. 7.05 Describe the location, and7.05 Describe the location, and function of CSF.function of CSF. (ventricles, subarachnoid space)(ventricles, subarachnoid space) Cavities within the brainCavities within the brain Lateral ventricles (2) - located within eachLateral ventricles (2) - located within each hemisphere in the cerebrumhemisphere in the cerebrum Third ventricle - a vertical slit between theThird ventricle - a vertical slit between the lateral ventricles and inferior to the rightlateral ventricles and inferior to the right and left halves of the thalamusand left halves of the thalamus Fourth ventricle - space between theFourth ventricle - space between the brainstem and the cerebellumbrainstem and the cerebellum
  • 28. 7.05 Describe the location, and7.05 Describe the location, and function of CSF.function of CSF. (Choroid Plexus)(Choroid Plexus) Network of capillaries in the walls of theNetwork of capillaries in the walls of the ventriclesventricles Covered with ependymal cells that form theCovered with ependymal cells that form the cerebrospinal fluidcerebrospinal fluid These ependymal cells are so close togetherThese ependymal cells are so close together they form the blood-brain barrier.they form the blood-brain barrier. – Selectively permeable barrierSelectively permeable barrier – Protects the brain and spinal cord fromProtects the brain and spinal cord from potentially harmful substances in the bloodpotentially harmful substances in the blood
  • 29. 7.05 Blood Supply to the Brain7.05 Blood Supply to the Brain One of the most metabolically activeOne of the most metabolically active organs in the bodyorgans in the body Makes up only 2-3% of body weight butMakes up only 2-3% of body weight but uses about 20% of available Ouses about 20% of available O22 at restat rest Well supplied with OWell supplied with O22 and nutrientsand nutrients Only nutritional source for brainOnly nutritional source for brain metabolic activity is glucosemetabolic activity is glucose Capillaries in the brain are much lessCapillaries in the brain are much less leaky than other capillaries in the bodyleaky than other capillaries in the body and form a blood brain barrierand form a blood brain barrier
  • 30. 7.05 Describe the function of CSF.7.05 Describe the function of CSF. Mechanical ProtectionMechanical Protection – Serves as a shock absorbing mediumServes as a shock absorbing medium – Buoys the brain so it literally floats withinBuoys the brain so it literally floats within the cranial cavitythe cranial cavity Chemical ProtectionChemical Protection – Provides an optimal chemical environmentProvides an optimal chemical environment for neural signalingfor neural signaling CirculationCirculation – Acts as a medium for exchange of nutrientsActs as a medium for exchange of nutrients and waste products between the blood andand waste products between the blood and nervous tissuenervous tissue
  • 31. 7.05 Ventricles of the Brain7.05 Ventricles of the Brain
  • 35.
  • 36. 7.06 Identify the structures responsible for7.06 Identify the structures responsible for the maintenance and protection of thethe maintenance and protection of the central nervous system.central nervous system. Protected by the cranial bones and the cranial meningesProtected by the cranial bones and the cranial meninges – Dura MaterDura Mater - outer layer- outer layer – ArachnoidArachnoid - middle layer- middle layer – Pia MaterPia Mater - inner layer- inner layer Also protected byAlso protected by cerebrospinal fluid (CSF)cerebrospinal fluid (CSF) – fluid that nourishes and protects the brain and spinal cordfluid that nourishes and protects the brain and spinal cord – continuously circulates through the subarachnoid spacecontinuously circulates through the subarachnoid space around the brain and throughout the cavities within thearound the brain and throughout the cavities within the brainbrain
  • 37. 7.06 Meninges7.06 Meninges Connective tissue covering foundConnective tissue covering found around the brain and spinal cordaround the brain and spinal cord Three layered membraneThree layered membrane – Dura Mater - outer most layerDura Mater - outer most layer dense irregular connective tissuedense irregular connective tissue – Arachnoid - middle layerArachnoid - middle layer spider web arrangement of collagen fibersspider web arrangement of collagen fibers – Pia Mater - inner most meningesPia Mater - inner most meninges very delicate layer of thin tissuevery delicate layer of thin tissue
  • 38. 7.06 Meninges of the Brain7.06 Meninges of the Brain
  • 39. 7.067.06 MeningesMeninges of theof the Spinal CordSpinal Cord Dura MaterDura Mater ArachnoidArachnoid -Subarachnoid Space-Subarachnoid Space Pia MaterPia Mater
  • 41. 7.07 Identify the four principle7.07 Identify the four principle parts of the brain.parts of the brain. cerebrum, cerebellum, brain stem,cerebrum, cerebellum, brain stem, diencephalondiencephalon One of the largest organs in the bodyOne of the largest organs in the body Controls all mental functionsControls all mental functions Component of the CNSComponent of the CNS Composed of over 100 billion neuronsComposed of over 100 billion neurons Comprises 2-3% of body weightComprises 2-3% of body weight Utilizes over 20% of body’s energyUtilizes over 20% of body’s energy
  • 42. CEREBRUMCEREBRUM - occupies most of the- occupies most of the cranium and is divided into right and leftcranium and is divided into right and left halves called hemisphereshalves called hemispheres CEREBELLUMCEREBELLUM - the posterior-inferior- the posterior-inferior portion of the brainportion of the brain BRAIN STEMBRAIN STEM - consists of the medulla- consists of the medulla oblongata, thoblongata, thee pons, and the midbrainpons, and the midbrain – it is continuous with the spinal cordit is continuous with the spinal cord DIENCEPHALONDIENCEPHALON - located above the- located above the brainstem, composed primarily of the:brainstem, composed primarily of the: – ThalamusThalamus -- HypothalamusHypothalamus
  • 43.
  • 45. 7.08 Describe the functions of7.08 Describe the functions of the three structures of thethe three structures of the brain stem.brain stem. The most inferior portion of the brainThe most inferior portion of the brain Connects the brain to the spinal cordConnects the brain to the spinal cord Composed of Three AreasComposed of Three Areas – The Medulla OblongataThe Medulla Oblongata – The PonsThe Pons – The MidbrainThe Midbrain
  • 46. 7.08 The Medulla Oblongata7.08 The Medulla Oblongata Most inferior portion of the brain stemMost inferior portion of the brain stem Connects the brain stem to the spinalConnects the brain stem to the spinal cordcord Respiratory Center ***Respiratory Center *** – Adjusts rhythm and depth of breathingAdjusts rhythm and depth of breathing Cardiovascular Center ***Cardiovascular Center *** – Regulates heart rate and contraction forceRegulates heart rate and contraction force – Influences vasoconstriction andInfluences vasoconstriction and vasodilationvasodilation Also controls coughing, vomiting,Also controls coughing, vomiting, swallowing, and hiccuppingswallowing, and hiccupping
  • 47. The Medulla OblongataThe Medulla Oblongata
  • 48. The Medulla OblongataThe Medulla Oblongata
  • 49. 7.08 The Pons7.08 The Pons Lies superior to the medulla oblongataLies superior to the medulla oblongata Together with the respiratory center inTogether with the respiratory center in the medulla helps control respirationthe medulla helps control respiration
  • 51. 7.08 The Midbrain7.08 The Midbrain Superior to the ponsSuperior to the pons Connects the brain stem to theConnects the brain stem to the diencephalondiencephalon
  • 53. Pons and MidbrainPons and Midbrain
  • 54. 7.09 Describe the structures and7.09 Describe the structures and functions of the diencephalon.functions of the diencephalon. Area of the brain containing the:Area of the brain containing the: – ThalamusThalamus – HypothalamusHypothalamus
  • 55. 7.09 The Thalamus7.09 The Thalamus Oval structure that makes up 80% of theOval structure that makes up 80% of the diencephalondiencephalon Comprised of a pair of oval massesComprised of a pair of oval masses (mostly gray matter)(mostly gray matter) PrinciplePrinciple relay stationrelay station between thebetween the various sections of the brainvarious sections of the brain
  • 57.
  • 58.
  • 59. 7.09 The Hypothalamus7.09 The Hypothalamus A small portion of the diencephalonA small portion of the diencephalon located below the thalamuslocated below the thalamus One of the main regulators ofOne of the main regulators of homeostasis in the bodyhomeostasis in the body Lacks a blood brain barrierLacks a blood brain barrier Partially protected by the sella turcicaPartially protected by the sella turcica of the sphenoid boneof the sphenoid bone
  • 60. 7.09 Functions of the7.09 Functions of the HypothalamusHypothalamus Coordinates Nervous System andCoordinates Nervous System and Endocrine System activities to maintainEndocrine System activities to maintain HomeostasisHomeostasis – Thirst, Hunger, SatietyThirst, Hunger, Satiety – Sleep Patterns and Waking StatesSleep Patterns and Waking States – Sex Drive, Maturation, Aggression, andSex Drive, Maturation, Aggression, and RageRage – influences movement of food through theinfluences movement of food through the Gastrointestinal TractGastrointestinal Tract – production and secretion of hormones Thatproduction and secretion of hormones That control other Endocrine Glandscontrol other Endocrine Glands
  • 63. 7.10 Describe the locations and functions7.10 Describe the locations and functions of theof the four lobesfour lobes of the cerebrum.of the cerebrum. Largest division of the brainLargest division of the brain Occupies most of the craniumOccupies most of the cranium Accounts for 85% of brain massAccounts for 85% of brain mass Divided into right and left hemispheresDivided into right and left hemispheres – Longitudinal FissureLongitudinal Fissure – Corpus CallosumCorpus Callosum Cerebral cortex - the outer surface areaCerebral cortex - the outer surface area of the cerebrumof the cerebrum – Composed mainly of gray matterComposed mainly of gray matter – Contains billions of neuronsContains billions of neurons
  • 65.
  • 66. 7.10 Describe the locations and7.10 Describe the locations and functions of the four lobes of thefunctions of the four lobes of the cerebrum.cerebrum. Named after the bones that cover themNamed after the bones that cover them – Frontal LobeFrontal Lobe – Parietal LobeParietal Lobe – Temporal LobeTemporal Lobe – Occipital LobeOccipital Lobe
  • 67. 7.10 Frontal Lobe7.10 Frontal Lobe Motor AreasMotor Areas – Controls movement of voluntary skeletalControls movement of voluntary skeletal musclesmuscles Association AreasAssociation Areas – Carry on high level intellectual processingCarry on high level intellectual processing Problem SolvingProblem Solving - Reasoning- Reasoning - Planning- Planning ConcentrationConcentration - Memory- Memory - Behavior- Behavior EmotionsEmotions - Expressions- Expressions
  • 68. 7.10 Parietal Lobe7.10 Parietal Lobe Sensory AreasSensory Areas – Interprets sensations such as:Interprets sensations such as: – touch - pressure - pain on the surface of thetouch - pressure - pain on the surface of the skinskin Association AreasAssociation Areas – Understanding of speechUnderstanding of speech – Using words to express thoughts andUsing words to express thoughts and feelingsfeelings
  • 69. 7.10 Temporal Lobe7.10 Temporal Lobe Sensory AreasSensory Areas – Hearing and balanceHearing and balance Association AreasAssociation Areas – Interpret sensory experiencesInterpret sensory experiences – Memory of visual scenes - music - smellsMemory of visual scenes - music - smells and other complex sensory patternsand other complex sensory patterns
  • 70. 7.10 Occipital Lobe7.10 Occipital Lobe Sensory AreasSensory Areas – Visual processing and interpretationVisual processing and interpretation Association AreasAssociation Areas – Combines visual images with sensoryCombines visual images with sensory experienceexperience
  • 71. 7.11 Explain the major7.11 Explain the major functions of the cerebellum.functions of the cerebellum. Second largest portion of the brainSecond largest portion of the brain Occupies the inferior and posteriorOccupies the inferior and posterior aspects of the cranial cavityaspects of the cranial cavity Processes sensory informationProcesses sensory information – BalanceBalance - Coordination- Coordination – Maintains postural equilibriumMaintains postural equilibrium
  • 74.
  • 75. 7.11 Cerebellar Test7.11 Cerebellar Test Finger to Finger TestFinger to Finger Test Finger to Nose TestFinger to Nose Test Holme’s Sign (overreaction)Holme’s Sign (overreaction) Romberg’s Test (Eyes Closed)Romberg’s Test (Eyes Closed)
  • 76. 7.12 Sequence the major events7.12 Sequence the major events when the nerve impulsewhen the nerve impulse (action potential) is initiated(action potential) is initiated and transmitted through a neuron.and transmitted through a neuron. The transmission of nerveThe transmission of nerve (electrical) impulses from(electrical) impulses from nervous tissue to othernervous tissue to other nervous tissue, organs,nervous tissue, organs, glands, and muscles.glands, and muscles.
  • 77. 7.12 Neuron Membrane Potential7.12 Neuron Membrane Potential
  • 78. 7.12 Neuron Action Potential7.12 Neuron Action Potential
  • 79. 7.12 Transmission of Nerve7.12 Transmission of Nerve ImpulsesImpulses An electrical event due to movement ofAn electrical event due to movement of ions across a membraneions across a membrane Also called an action potentialAlso called an action potential – Lasts about 1 msec (1/1000 of a second)Lasts about 1 msec (1/1000 of a second) – Dependent upon diameter of the axonDependent upon diameter of the axon A-(thick myelin/fast), B-(thin myelin/moderate),A-(thick myelin/fast), B-(thin myelin/moderate), C-(unmyelin/slow) fibersC-(unmyelin/slow) fibers larger diameter axons - 0.4 msec (1/2500 sec)larger diameter axons - 0.4 msec (1/2500 sec) – 2500 impulses per second2500 impulses per second smaller diameter axons - 4 msec (1/250 sec)smaller diameter axons - 4 msec (1/250 sec) – 250 impulses per second250 impulses per second
  • 80. 7.12 All or None Principle7.12 All or None Principle If depolarization reaches a threshold, anIf depolarization reaches a threshold, an action potential (impulse) is conductedaction potential (impulse) is conducted Each action potential (impulse) isEach action potential (impulse) is conducted at maximumconducted at maximum strength unless there arestrength unless there are toxic materials withintoxic materials within the cell or the membranethe cell or the membrane has been disruptedhas been disrupted
  • 81. 7.12 Neuron Impulse7.12 Neuron Impulse
  • 82. 7.12 Transmission of Nerve7.12 Transmission of Nerve Impulses at SynapsesImpulses at Synapses Most nervous conduction is fromMost nervous conduction is from neuron to neuron (interneurons - 90%)neuron to neuron (interneurons - 90%) Types of SynapsesTypes of Synapses – Axon to dendriteAxon to dendrite – Axon to somaAxon to soma – Axon to axonAxon to axon Two ways to transmit impulses across aTwo ways to transmit impulses across a synapsesynapse – Electrical SynapsesElectrical Synapses – Chemical SynapsesChemical Synapses
  • 84. 7.12 Types of Impulse Conduction7.12 Types of Impulse Conduction Continuous ConductionContinuous Conduction - step by step- step by step depolarization of each sequential,depolarization of each sequential, adjacent area of of the nerve celladjacent area of of the nerve cell membranemembrane – typical of unmyelinated nerve fiberstypical of unmyelinated nerve fibers – type of action potential in muscle fiberstype of action potential in muscle fibers Saltatory ConductionSaltatory Conduction - the jumping of- the jumping of an action potential across specializedan action potential across specialized neurofibril nodes along the axonneurofibril nodes along the axon – Nodes of RanvierNodes of Ranvier
  • 85. 7.12 Nerve Conduction7.12 Nerve Conduction
  • 86. 7.13 Explain the role of each of7.13 Explain the role of each of the components of a reflex arc.the components of a reflex arc. ((reflexreflex,, reflex arc:reflex arc: receptorreceptor,, sensory neuronsensory neuron,, associationassociation [interneuron] neuron[interneuron] neuron,, motor neuronmotor neuron,, effectoreffector))
  • 87. 7.13 The Reflex Arc:7.13 The Reflex Arc: receptor, sensoryreceptor, sensory neuron, association [interneuron] neuron,neuron, association [interneuron] neuron, motor neuron, effectormotor neuron, effector A response by the body involving onlyA response by the body involving only the body segment being affected andthe body segment being affected and the spinal cordthe spinal cord – Brain does not have to be involvedBrain does not have to be involved Receptor - the distal end of a sensoryReceptor - the distal end of a sensory neuron (dendrite)neuron (dendrite) – Responds to a specific stimulusResponds to a specific stimulus a change in internal or external environmenta change in internal or external environment – Triggers a nerve impulseTriggers a nerve impulse
  • 88. Sensory Neuron - the neuron located inSensory Neuron - the neuron located in the gray matter of the spinal cordthe gray matter of the spinal cord – conducts impulses from the receptor to theconducts impulses from the receptor to the spinal cordspinal cord Integrating Center - a region within theIntegrating Center - a region within the CNS (spinal cord or brain) thatCNS (spinal cord or brain) that interprets the information from theinterprets the information from the sensory neuron and initiates ansensory neuron and initiates an appropriate responseappropriate response Motor Neurons - the neurons arisingMotor Neurons - the neurons arising from the integrating center that relay afrom the integrating center that relay a nerve impulse to the part of the bodynerve impulse to the part of the body that will respond to the stimulusthat will respond to the stimulus
  • 89. Effector - the part of the body thatEffector - the part of the body that responds to the motor nerve impulseresponds to the motor nerve impulse (usually a muscle or a gland)(usually a muscle or a gland) – Effector - skeletal muscle - somatic reflexEffector - skeletal muscle - somatic reflex – Effector - cardiac, smooth muscle, or glandEffector - cardiac, smooth muscle, or gland -visceral reflex-visceral reflex
  • 90. 7.13 The Peripheral7.13 The Peripheral Nervous System (PNS)Nervous System (PNS) Connects sensory receptors, muscles,Connects sensory receptors, muscles, and glands in the peripheral parts of theand glands in the peripheral parts of the body to the central nervous systembody to the central nervous system Consists of cranial and spinal nervesConsists of cranial and spinal nerves Afferent Neurons (Sensory)Afferent Neurons (Sensory) – conduct nerve impulses from sensoryconduct nerve impulses from sensory receptors toward the CNSreceptors toward the CNS Efferent Neurons (Motor)Efferent Neurons (Motor) – conduct nerve impulses fromconduct nerve impulses from the CNS to muscles and glandsthe CNS to muscles and glands CNSCNS PNSPNS
  • 91. 7.13 The Reflex Arc7.13 The Reflex Arc
  • 92. 7.13 Reflex arc (Reflexes).7.13 Reflex arc (Reflexes). Fast, predictable, automatic responsesFast, predictable, automatic responses to changes in the environment that helpto changes in the environment that help maintain homeostasismaintain homeostasis Somatic Reflexes - involve skeletalSomatic Reflexes - involve skeletal musclesmuscles Visceral (Autonomic) Reflexes - involveVisceral (Autonomic) Reflexes - involve responses of smooth muscles, the heart,responses of smooth muscles, the heart, and glandsand glands Involve the spinal nervesInvolve the spinal nerves
  • 93. 7.13 Reflex Arc Examples7.13 Reflex Arc Examples Stretch Reflex - results in theStretch Reflex - results in the contraction of a muscle if it has beencontraction of a muscle if it has been stretched suddenlystretched suddenly Tendon Reflex - results in theTendon Reflex - results in the contraction of a muscle when a tendoncontraction of a muscle when a tendon is stretched suddenlyis stretched suddenly Flexor (Withdrawal) Reflex - suddenFlexor (Withdrawal) Reflex - sudden contraction and removal of a bodycontraction and removal of a body segment as a result of a pain stimulussegment as a result of a pain stimulus
  • 94. 7.13 Tendon Reflex7.13 Tendon Reflex
  • 96. 07.14 Identify the following07.14 Identify the following diseases or disorders of thediseases or disorders of the nervous system.nervous system. (ALS, Alzheimer’s, bacterial(ALS, Alzheimer’s, bacterial meningitis, cerebral palsy,meningitis, cerebral palsy, epilepsy, multipleepilepsy, multiple sclerosis, Parkinson’s,sclerosis, Parkinson’s, Guillain-Barre syndrome)Guillain-Barre syndrome)
  • 97. 7.14 Amyotrophic Lateral7.14 Amyotrophic Lateral Sclerosis (ALS)Sclerosis (ALS) Also known as Lou Gehrig’s DiseaseAlso known as Lou Gehrig’s Disease A relatively rare neurological disorderA relatively rare neurological disorder A syndrome marked by muscular weaknessA syndrome marked by muscular weakness and atrophy with spasticity and hyperflexionand atrophy with spasticity and hyperflexion due to degeneration of the motor neurons ofdue to degeneration of the motor neurons of the spinal cord, medulla, and cortexthe spinal cord, medulla, and cortex A degenerative diseaseA degenerative disease No known cureNo known cure
  • 98. 7.14 Alzheimer’s Disease (AD)7.14 Alzheimer’s Disease (AD) Disabling neurological disorder thatDisabling neurological disorder that effects about 11% of the populationeffects about 11% of the population Fourth leading cause of brain deathFourth leading cause of brain death among the elderlyamong the elderly A chronic, organic, mental disorder, aA chronic, organic, mental disorder, a form of pre-senile dementia due toform of pre-senile dementia due to atrophy of neurons of the frontal andatrophy of neurons of the frontal and occipital lobesoccipital lobes AD patients usually die fromAD patients usually die from complications due to being bedriddencomplications due to being bedridden
  • 99. 7.14 Bacterial Meningitis7.14 Bacterial Meningitis Infection of the meninges by theInfection of the meninges by the bacterium Haemophilus Influenzaebacterium Haemophilus Influenzae Usually affects children under age 5Usually affects children under age 5 Symptoms include severe headachesSymptoms include severe headaches and feverand fever Can lead to brain damage and evenCan lead to brain damage and even death if not treateddeath if not treated
  • 101. 7.14 Cerebral Palsy (CP)7.14 Cerebral Palsy (CP) A group of motor disorders due to lossA group of motor disorders due to loss of muscle controlof muscle control Caused by damage to the motor areasCaused by damage to the motor areas of the brain during fetal development,of the brain during fetal development, birth, or infancybirth, or infancy About 70% of CP individuals areAbout 70% of CP individuals are somewhat mentally retarded due to thesomewhat mentally retarded due to the inability to hear well or speak fluentlyinability to hear well or speak fluently Not a progressive disease but theNot a progressive disease but the symptoms are irreversiblesymptoms are irreversible
  • 102. 7.14 Epilepsy7.14 Epilepsy Short, recurrent, periodic, attacks ofShort, recurrent, periodic, attacks of motor, sensory, or psychologicalmotor, sensory, or psychological malfunctionmalfunction Characterized by seizures which canCharacterized by seizures which can result in involuntary skeletal muscleresult in involuntary skeletal muscle contraction, loss of muscle control,contraction, loss of muscle control, inability to sense light, noise, and smell,inability to sense light, noise, and smell, and loss of consciousnessand loss of consciousness Most epileptic seizures are idiopathicMost epileptic seizures are idiopathic
  • 103. 7.14 Multiple Sclerosis (MS)7.14 Multiple Sclerosis (MS) Demyelinating disease of the CNSDemyelinating disease of the CNS The sheaths deteriorates toThe sheaths deteriorates to sclerosesscleroses – hardened scars or plaqueshardened scars or plaques ““short circuits” nerve transmissionshort circuits” nerve transmission Cause is unknownCause is unknown – May be a type of an autoimmune diseaseMay be a type of an autoimmune disease No known cureNo known cure Progressive loss of function withProgressive loss of function with intermittent periods of remissionintermittent periods of remission
  • 104. 7.14 Guillain-Barre syndrome7.14 Guillain-Barre syndrome Demyelinating disease of the PNSDemyelinating disease of the PNS Caused by an Autoimmune diseaseCaused by an Autoimmune disease Signs and symptomsSigns and symptoms – muscle weakness in legs and difficult breathingmuscle weakness in legs and difficult breathing 60% recover completely within a year.60% recover completely within a year. 5-10% recover with severe disability5-10% recover with severe disability low percent death ratelow percent death rate
  • 105. 7.14 Parkinson’s Disease (PD)7.14 Parkinson’s Disease (PD) A progressive disorder of the CNS thatA progressive disorder of the CNS that usually affects individuals over 60usually affects individuals over 60 Cause is unknown but a toxicCause is unknown but a toxic environmental factor is suspectedenvironmental factor is suspected Chemical basis of the disease appears toChemical basis of the disease appears to be to little dopamine and too much Achbe to little dopamine and too much Ach Treatment includes increasing levels ofTreatment includes increasing levels of dopamine and decreasing Achdopamine and decreasing Ach – Difficult because dopamine does not crossDifficult because dopamine does not cross the blood brain barrierthe blood brain barrier
  • 106. A chronic nervous diseaseA chronic nervous disease characterized by a fine, slowlycharacterized by a fine, slowly spreading tremor, muscle weaknessspreading tremor, muscle weakness and rigidity, and a peculiar gaitand rigidity, and a peculiar gait Other causes may include brain damageOther causes may include brain damage at birth, metabolic disturbances,at birth, metabolic disturbances, infections, toxins, vascularinfections, toxins, vascular disturbances, head injuries, and tumorsdisturbances, head injuries, and tumors and abscesses of the brainand abscesses of the brain Usually can be controlled with drugUsually can be controlled with drug therapytherapy – GABA - gamma aminobutyric acidGABA - gamma aminobutyric acid
  • 107. Symptoms include muscle tremor,Symptoms include muscle tremor, muscle rigidity, bradykinesia,muscle rigidity, bradykinesia, hypokinesia or dyskinesia, speech andhypokinesia or dyskinesia, speech and walking impairmentwalking impairment Attempting to transplant fetal nervousAttempting to transplant fetal nervous tissue into the damaged area of thetissue into the damaged area of the brain of some Parkinson’s Diseasebrain of some Parkinson’s Disease patientspatients
  • 108. 7.14 Cerebral Vascular7.14 Cerebral Vascular AccidentAccident (CVA) - Stroke(CVA) - Stroke The most common brain disorderThe most common brain disorder Characterized by slurred speech, loss ofCharacterized by slurred speech, loss of or blurred vision, dizziness, weakness,or blurred vision, dizziness, weakness, paralysis of a limb or hemiplegia, coma,paralysis of a limb or hemiplegia, coma, and deathand death Ischemic CVA - due to lack of bloodIschemic CVA - due to lack of blood supply to a particular area of the brainsupply to a particular area of the brain Hemorrhagic CVA - due to the ruptureHemorrhagic CVA - due to the rupture of a blood vessel in the brainof a blood vessel in the brain
  • 109.
  • 110. 7.14 Risk Factors for Stroke7.14 Risk Factors for Stroke hypertensionhypertension heart diseaseheart disease smokingsmoking diabetesdiabetes atherosclerosisatherosclerosis hyperlipidemiahyperlipidemia obesityobesity excessive alcohol intakeexcessive alcohol intake
  • 112. SensesSenses Specialized structures of theSpecialized structures of the nervous system which providenervous system which provide information about theinformation about the environment in which we live toenvironment in which we live to help maintain homeostasishelp maintain homeostasis
  • 113. Functions ofFunctions of Special SensesSpecial Senses Sensory - monitoring the body and theSensory - monitoring the body and the external environment for changingexternal environment for changing conditionsconditions
  • 114. Sensory PathwaysSensory Pathways All pathways begin with a receptor andAll pathways begin with a receptor and the sensory information is transmittedthe sensory information is transmitted to the CNSto the CNS Always begins with a stimulusAlways begins with a stimulus – change in the environmentchange in the environment
  • 115. ReceptorsReceptors Structures which provide feedbackStructures which provide feedback about the environmentabout the environment Are impulse specificAre impulse specific – Only respond to one type of stimulusOnly respond to one type of stimulus Many have sensory functionMany have sensory function adaptationsadaptations – May end as bare dendrites or be a complexMay end as bare dendrites or be a complex organorgan
  • 116. VisionVision The most complex of the special sensesThe most complex of the special senses – Over 70% of the sensory receptors in theOver 70% of the sensory receptors in the body are photoreceptors for sightbody are photoreceptors for sight Visual organs, the eyes are supportedVisual organs, the eyes are supported by a number of accessory structuresby a number of accessory structures and internal organsand internal organs – Dependent upon photoreceptors in theDependent upon photoreceptors in the eyeseyes
  • 117. 7.15 Describe the principle7.15 Describe the principle anatomical structures of the eye.anatomical structures of the eye. 1.1. Accessory structuresAccessory structures:: eyelideyelid,, conjunctivaconjunctiva,, lacrimal apparatuslacrimal apparatus,, extrinsicextrinsic musclesmuscles.. 2.2. Layers of the eyeballLayers of the eyeball:: fibrous tunicfibrous tunic (sclera, cornea),(sclera, cornea), vascular tunicvascular tunic (choroid,(choroid, ciliary body, iris, lens, pupil),ciliary body, iris, lens, pupil), nervous tunicnervous tunic (retina).(retina).
  • 119. 7.15 Accessory Structures7.15 Accessory Structures of the Eyeof the Eye Eyelids - protects the anterior surfaceEyelids - protects the anterior surface – Conjunctiva - the mucous membrane of the eyelidConjunctiva - the mucous membrane of the eyelid – Helps moisten and lubricate the eyeballHelps moisten and lubricate the eyeball Lacrimal Apparatus - secretes tearsLacrimal Apparatus - secretes tears – lacrimal glandlacrimal gland - lacrimal sac- lacrimal sac – lacrimal canalslacrimal canals - nasolacrimal duct- nasolacrimal duct – moistens and lubricates the eyeballmoistens and lubricates the eyeball – fights against infection (enzymes in tears)fights against infection (enzymes in tears) Extrinsic Muscles of the Eyeball (6)Extrinsic Muscles of the Eyeball (6) – skeletal muscles that move the eyeballskeletal muscles that move the eyeball
  • 120. 7.15 Six Extrinsic Eye Muscles7.15 Six Extrinsic Eye Muscles Lateral Rectus (LR)Lateral Rectus (LR) Medial Rectus (MR)Medial Rectus (MR) Inferior Rectus (IR)Inferior Rectus (IR) Superior Rectus (SR)Superior Rectus (SR) Superior Oblique (SO)Superior Oblique (SO) Inferior Oblique (IO)Inferior Oblique (IO) H in space tests three cranialH in space tests three cranial nerves. SO4,LR6, all else 3.nerves. SO4,LR6, all else 3. Trochlear-4Trochlear-4 Abducens-6Abducens-6 Oculomotor-3Oculomotor-3
  • 122. 7.15 Structure of the Eye7.15 Structure of the Eye The wall consists of three layers ofThe wall consists of three layers of tissue or tunicstissue or tunics Fibrous Tunic - outer layerFibrous Tunic - outer layer Vascular Tunic - middle layerVascular Tunic - middle layer Nervous Tunic - inner layerNervous Tunic - inner layer
  • 123. 7.15 Fibrous Tunic7.15 Fibrous Tunic Thick, outermost layer of the eyeballThick, outermost layer of the eyeball Sclera - the posterior “white” portionSclera - the posterior “white” portion – Forms most of the fibrous tunicForms most of the fibrous tunic – The “whites” of the eyeThe “whites” of the eye Cornea - the anterior transparentCornea - the anterior transparent portion of the fibrous tunicportion of the fibrous tunic – Bulges outward slightlyBulges outward slightly
  • 125. 7.15 Vascular Tunic7.15 Vascular Tunic Extremely vascularExtremely vascular Supplies blood to numerous structuresSupplies blood to numerous structures of the eyeof the eye – ChoroidChoroid - Ciliary Body- Ciliary Body – IrisIris - Lens- Lens – PupilPupil
  • 127. 7.15 Vascular Tunic7.15 Vascular Tunic Choroid - posterior, thin portion of theChoroid - posterior, thin portion of the vascular tunicvascular tunic – A thin, dark brown membrane that lines most ofA thin, dark brown membrane that lines most of the internal surface of the sclerathe internal surface of the sclera Ciliary Body - anterior, thick portion of theCiliary Body - anterior, thick portion of the vascular tunicvascular tunic – Thickest part of the vascular tunicThickest part of the vascular tunic – Consists of smooth muscle fibersConsists of smooth muscle fibers – Attaches to the lens by ligamentsAttaches to the lens by ligaments – Changes the thickness and shape of the lens.Changes the thickness and shape of the lens.
  • 129. 7.15 Vascular Tunic7.15 Vascular Tunic Iris - anterior, colored portion of the VascularIris - anterior, colored portion of the Vascular TunicTunic – contraction of it’s smooth muscle accounts forcontraction of it’s smooth muscle accounts for dilation or constriction of the Pupils (openings todilation or constriction of the Pupils (openings to the inner cavities of the eyes)the inner cavities of the eyes) Lens - special tissue which focuses and directsLens - special tissue which focuses and directs light entering the eyelight entering the eye – suspended by the Ciliary Bodysuspended by the Ciliary Body – located behind the Irislocated behind the Iris – alteration of the shape of the lens to accommodatealteration of the shape of the lens to accommodate for near or far vision focusing (Accommodation)for near or far vision focusing (Accommodation)
  • 131. Iris – Pupil DiameterIris – Pupil Diameter
  • 132. 7.15 Nervous Tunic7.15 Nervous Tunic The inner layer of the eyeThe inner layer of the eye Retina - a thin fragile layer of neurons thatRetina - a thin fragile layer of neurons that forms the inner lining of the eyeball’sforms the inner lining of the eyeball’s posterior wallposterior wall – Lines the posterior cavity and contains theLines the posterior cavity and contains the photoreceptor cells (rods and cones), bipolarphotoreceptor cells (rods and cones), bipolar neurons, and ganglion cellsneurons, and ganglion cells Optic Nerve - axons and ganglion cellsOptic Nerve - axons and ganglion cells – Transmits images to the occipital lobe of the brainTransmits images to the occipital lobe of the brain for interpretation of what we seefor interpretation of what we see
  • 134. 7.15 Rods and Cones7.15 Rods and Cones Rods - elongated cylindrical dendritesRods - elongated cylindrical dendrites that are sensitive to varying lightthat are sensitive to varying light conditionsconditions – Allows us to see under varying lightAllows us to see under varying light intensities (night vision)intensities (night vision) Cones - dendrites with tapered endsCones - dendrites with tapered ends – Color sensitiveColor sensitive – Determines the “sharpness” of visionDetermines the “sharpness” of vision
  • 136. Rods and ConesRods and Cones
  • 137. 7.15 Other Structures of the7.15 Other Structures of the Nervous TunicNervous Tunic Optic Disc - blind spot where the opticOptic Disc - blind spot where the optic nerve exits the retinanerve exits the retina Fovea Centralis - an area of the retinaFovea Centralis - an area of the retina containing many cone cellscontaining many cone cells – the area of sharpest visionthe area of sharpest vision
  • 139.
  • 140. Elements of Vision in the EyeElements of Vision in the Eye Vision spectrum of the eyeVision spectrum of the eye – only detect three colorsonly detect three colors – RedRed - Green- Green - Blue- Blue Aspects of vision of the eyeAspects of vision of the eye – colorcolor – motionmotion – formform – depthdepth
  • 141. RefractionRefraction the “bending” of light rays as it travelsthe “bending” of light rays as it travels through the eyethrough the eye the pathway of light as it travels through thethe pathway of light as it travels through the eyeeye influenced by:influenced by: – shape of the lensshape of the lens – shape and thickness of the corneashape and thickness of the cornea – amount and consistency of the Aqueous andamount and consistency of the Aqueous and Vitreous HumorVitreous Humor
  • 144. Physiology of VisionPhysiology of Vision Rods and cones convert light wavesRods and cones convert light waves into a series of signals that results in theinto a series of signals that results in the generation of an action potential in thegeneration of an action potential in the ganglion cellsganglion cells – Both rods and cones contain pigments thatBoth rods and cones contain pigments that decompose when exposed to lightdecompose when exposed to light – The decomposition of the pigments is whatThe decomposition of the pigments is what generates the action potentialgenerates the action potential
  • 145. Visual PathwaysVisual Pathways From the rods and cones, the nervousFrom the rods and cones, the nervous impulse is passed on to bipolar neurons andimpulse is passed on to bipolar neurons and then on to ganglion cellsthen on to ganglion cells Axons from the ganglion cells extend out ofAxons from the ganglion cells extend out of the eye and converge to from the optic nervethe eye and converge to from the optic nerve The optic nerves cross behind the eye at anThe optic nerves cross behind the eye at an area known as the optic chiasmaarea known as the optic chiasma The optic nerve terminates at the thalamusThe optic nerve terminates at the thalamus
  • 146. Visual PathwaysVisual Pathways Visual impulses from the thalamus areVisual impulses from the thalamus are transmitted by other neurons to thetransmitted by other neurons to the occipital lobe of the cerebral cortexoccipital lobe of the cerebral cortex where the impulses are interpreted aswhere the impulses are interpreted as the sense of sight.the sense of sight.
  • 148. 7.16 Describe the principle7.16 Describe the principle anatomical structures of the ear.anatomical structures of the ear. Outer EarOuter Ear -- auricle, auditory canal.auricle, auditory canal. Middle EarMiddle Ear - tympanic cavity, tympanic- tympanic cavity, tympanic membrane, auditory (Eustachian) tube,membrane, auditory (Eustachian) tube, auditory ossicles (malleus, incus, stapes).auditory ossicles (malleus, incus, stapes). Inner EarInner Ear - bony labyrinth, membranous- bony labyrinth, membranous labyrinth, semicircular canals, vestibule,labyrinth, semicircular canals, vestibule, cochlea, Organ of Corti.cochlea, Organ of Corti.
  • 150. 7.16 Outer Ear7.16 Outer Ear Direct sound waves toward theDirect sound waves toward the eardrumeardrum Auricle - the outer appendageAuricle - the outer appendage Auditory Canal - a tube that extendsAuditory Canal - a tube that extends into the temporal boneinto the temporal bone
  • 151. The Outer EarThe Outer Ear
  • 152. Middle EarMiddle Ear An air-filled space within the temporalAn air-filled space within the temporal bonebone Tympanic Cavity - contains theTympanic Cavity - contains the auditory ossiclesauditory ossicles – Smallest bones in the bodySmallest bones in the body Malleus (hammer)Malleus (hammer) Incus (anvil)Incus (anvil) Stapes (stirrup)Stapes (stirrup)
  • 153. 7.16 Middle Ear7.16 Middle Ear
  • 154. Auditory (Eustachian) Tube - a tubeAuditory (Eustachian) Tube - a tube from the middle ear to the pharynxfrom the middle ear to the pharynx – Allows for pressure equalization betweenAllows for pressure equalization between the middle ear and the atmospherethe middle ear and the atmosphere Tympanic Membrane (Eardrum) - thin,Tympanic Membrane (Eardrum) - thin, semitransparent membrane separatingsemitransparent membrane separating the outer and the middle earthe outer and the middle ear – Vibrates in response to sound wavesVibrates in response to sound waves striking itstriking it – The vibrations are then transmitted to theThe vibrations are then transmitted to the auditory ossiclesauditory ossicles
  • 155. Middle Ear StructuresMiddle Ear Structures
  • 156. The tympanic membrane and auditoryThe tympanic membrane and auditory ossicles convert sound waves intoossicles convert sound waves into mechanical movement within themechanical movement within the middle ear and then transmit thatmiddle ear and then transmit that motion to the “oval window”motion to the “oval window” The oval window opens into theThe oval window opens into the cochlea of the inner earcochlea of the inner ear Within the inner ear the vibrations ofWithin the inner ear the vibrations of the stapes causes the fluid within thethe stapes causes the fluid within the inner ear to move stimulating theinner ear to move stimulating the receptors for hearingreceptors for hearing
  • 157. 7.16 The Three Regions of7.16 The Three Regions of the Inner Earthe Inner Ear Formed by the canals of the bony labyrinthFormed by the canals of the bony labyrinth and the series of sacs of the membranousand the series of sacs of the membranous labyrinthlabyrinth Involved in both the sense of hearing and theInvolved in both the sense of hearing and the maintenance of balance and equilibriummaintenance of balance and equilibrium CochleaCochlea VestibuleVestibule Semicircular CanalsSemicircular Canals
  • 158. The Inner EarThe Inner Ear
  • 159. Inner Ear StructuresInner Ear Structures
  • 160. The Semicircular Canals - three loops that lieThe Semicircular Canals - three loops that lie at right angles to each otherat right angles to each other The Vestibule - the chamber between theThe Vestibule - the chamber between the cochlea and the semicircular canalscochlea and the semicircular canals – Both the semicircular canals and the vestibule areBoth the semicircular canals and the vestibule are involved with maintaining balance or equilibriuminvolved with maintaining balance or equilibrium The Cochlea - shape resembles a snail shellThe Cochlea - shape resembles a snail shell – Contains the organs of hearing (Corti)Contains the organs of hearing (Corti) Receptor cells that move in response to endolymphReceptor cells that move in response to endolymph motionmotion Releases neurotransmitters that stimulate nerve impulsesReleases neurotransmitters that stimulate nerve impulses
  • 162. Organ of CortiOrgan of Corti
  • 163. Cross Section of CochleaCross Section of Cochlea
  • 164. 7.16 Inner Ear (Labyrinth)7.16 Inner Ear (Labyrinth) Consists of a winding, complicated series ofConsists of a winding, complicated series of passageways or canalspassageways or canals Bony Labyrinth - a series of canals within theBony Labyrinth - a series of canals within the temporal bonetemporal bone – Contains perilymphContains perilymph Membranous Labyrinth - an internal series ofMembranous Labyrinth - an internal series of sacs and tubessacs and tubes – Contains endolymphContains endolymph – Conforms to the bony labyrinth shapeConforms to the bony labyrinth shape – Also helps form the shape of the three regions ofAlso helps form the shape of the three regions of the inner earthe inner ear
  • 166. Nerve PathwaysNerve Pathways Sound waves cause the tympanic membraneSound waves cause the tympanic membrane to vibrateto vibrate The vibration of the tympanic membraneThe vibration of the tympanic membrane causes the stapes to move back and forthcauses the stapes to move back and forth Movement of the stapes back and forthMovement of the stapes back and forth pushes the oval window in and outpushes the oval window in and out producing waves in the perilymph of theproducing waves in the perilymph of the inner earinner ear
  • 167. Pressure waves in the perilymph pushPressure waves in the perilymph push the vestibular membrane inwardthe vestibular membrane inward increasing the pressure of theincreasing the pressure of the endolymph within the cochlear ductendolymph within the cochlear duct The hair cells in the Organ of CortiThe hair cells in the Organ of Corti convert the motion of the endolymph toconvert the motion of the endolymph to the release of neurotransmittersthe release of neurotransmitters These neurotransmitters stimulate aThese neurotransmitters stimulate a nerve impulse in a sensory branch ofnerve impulse in a sensory branch of the Vestibulocochlear Nerve (CN #VIII)the Vestibulocochlear Nerve (CN #VIII)
  • 168. The impulse is then transferred throughThe impulse is then transferred through the midbrain and the thalamus andthe midbrain and the thalamus and finally terminates in the temporal lobefinally terminates in the temporal lobe of the cerebral cortex where the soundof the cerebral cortex where the sound is interpretedis interpreted
  • 170. 7.17 Identify the following7.17 Identify the following diseases or disorders associateddiseases or disorders associated with special senses:with special senses: presbyopiapresbyopia,, myopiamyopia,, hyperopiahyperopia,, cataractscataracts,, conjunctivitisconjunctivitis,, deafness (conductive,deafness (conductive, Sensorineural)Sensorineural),, glaucomaglaucoma,, macularmacular degenerationdegeneration,, middle ear infectionmiddle ear infection,, strabismusstrabismus,, tinnitustinnitus,, vertigovertigo..
  • 171. 7.17 Ametropia7.17 Ametropia (abnormal refracted light)(abnormal refracted light) MyopiaMyopia - nearsightedness- nearsightedness – Imaged focused in front of the retinaImaged focused in front of the retina HyperopiaHyperopia - farsightedness- farsightedness – Image focused in back of the retinaImage focused in back of the retina PresbyopiaPresbyopia - a defect in vision in- a defect in vision in advancing age involving loss ofadvancing age involving loss of accommodation or recession of nearaccommodation or recession of near point (results in farsightedness)point (results in farsightedness)
  • 172. 7.17 Cataracts7.17 Cataracts Abnormal loss of transparency of theAbnormal loss of transparency of the lenslens Vision becomes blurry or cloudyVision becomes blurry or cloudy Can be removed and have an artificialCan be removed and have an artificial lens insertedlens inserted Most often occurs to individuals overMost often occurs to individuals over the age of 50. Exposure tothe age of 50. Exposure to sunlight and smokingsunlight and smoking increases the risk.increases the risk.
  • 173. 7.17 Pink Eye/Cross-eyed7.17 Pink Eye/Cross-eyed Conjunctivitis - inflammation of theConjunctivitis - inflammation of the conjunctiva, the mucous membrane thatconjunctiva, the mucous membrane that lines the eyelid and is reflected to thelines the eyelid and is reflected to the eyeball. Also known as “Pink Eye”eyeball. Also known as “Pink Eye” Strabismus – “cross-eyed”Strabismus – “cross-eyed”
  • 174. 7.17 Glaucoma7.17 Glaucoma A group of eye diseases characterized byA group of eye diseases characterized by elevatedelevated intraocular pressureintraocular pressure in the eyein the eye resulting in atrophy of the optic nerve whichresulting in atrophy of the optic nerve which may lead to blindnessmay lead to blindness Caused by an obstruction of the outflow ofCaused by an obstruction of the outflow of the aqueous and vitreous humorthe aqueous and vitreous humor Minor cases can be treated with eye dropsMinor cases can be treated with eye drops More severe cases may require a surgicalMore severe cases may require a surgical incision into the iris of the eyeincision into the iris of the eye
  • 175. 7.17 Macular Degeneration7.17 Macular Degeneration The destruction or tearing away of the retinaThe destruction or tearing away of the retina from the back of the eyefrom the back of the eye Commonly occurs in the region of the retinaCommonly occurs in the region of the retina known as the macula luteaknown as the macula lutea Can be caused by:Can be caused by: – Vascular diseases (diabetes)Vascular diseases (diabetes) – Chronic increased pressure (glaucoma)Chronic increased pressure (glaucoma) – Sudden blow or impact to the head or eyeSudden blow or impact to the head or eye (Detached Retina)(Detached Retina)
  • 176. 7.17 Vertigo7.17 Vertigo A condition of dizziness and spatialA condition of dizziness and spatial disorientationdisorientation In some individuals it is due to heightsIn some individuals it is due to heights or fear of high placesor fear of high places A spinning sensation that may result inA spinning sensation that may result in loss of balance and equilibriumloss of balance and equilibrium
  • 177.
  • 178. 7.17 Tinnitus7.17 Tinnitus Ringing or tinkling sounds orRinging or tinkling sounds or sensations in the earsensations in the ear
  • 179. 7.17 Middle Ear Infection7.17 Middle Ear Infection Infection of the tympanic membrane orInfection of the tympanic membrane or other structures associated with theother structures associated with the middle ear (Otitis Media)middle ear (Otitis Media)
  • 180. 7.17 Deafness7.17 Deafness Loss of the ability to hearLoss of the ability to hear Conductive DeafnessConductive Deafness: deafness: deafness resulting from any condition thatresulting from any condition that prevents sound waves from beingprevents sound waves from being transmitted to the auditory receptorstransmitted to the auditory receptors Sensorineural DeafnessSensorineural Deafness: deafness due to: deafness due to defective function of the cochlea, organdefective function of the cochlea, organ of Corti, or the auditory nerveof Corti, or the auditory nerve