The urinary system

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Histology of urinary system

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The urinary system

  1. 1. Kidney Produce Ultrafiltate •Called Urine Urine Ureter Urinary bladder Urethra
  2. 2. Function •Osmoreguration •Remove metabolic waste
  3. 3. Endocrine function Erythropoietin - regurate erythropoietic in bone marrow Rennin - Control blood preesure Vitamin D – regurate balance calcium
  4. 4. General structure of kidney
  5. 5. Interior anatomy of kidney - Cortex 1. Convoluted par convoluta - Proximal and distal - Renal corpuscle - Interlobular a. v. - Afferent and efferent arteriole
  6. 6. 2. Straight par radiata - ascending and descending limbs of loob of henle straight tubule - Collecting duct Straight medullary rays
  7. 7. Medulla pyramid 2. Straight tube -Loop of henle -Vasa recta -Collecting duct
  8. 8. Devide 2 zone 1. Outer Zone - Mainly loop of henle Thick and Thin 2. Inner Zone renal pappila - loop of henle only thin - Cappillaries - vessel
  9. 9. vascurature
  10. 10. Nephron Type of nephron 1. Cortical 2. Juxtamedulla - Short-looped nephron - long thick segments , short thin segments - Long-looped nephron - short thick segments , long thin segments
  11. 11. Nephron
  12. 12. Nephron Consists of 1. Renal corpuscle 2. Renal tubule - filtration - resorption - secretion
  13. 13. Renal Corpuscle Consists of 1.Glomerulus 2.Bowman’s capsule - fenestrated capillary - fed by afferent arteriole and drains to efferent arteriole - double-walled epithelium capsule
  14. 14. Renal Corpuscle
  15. 15. Renal Tubule Proximal convoluted tubule Proximal straight tubule (thick descending limb) Thin descending limb Thin ascending limb Distal straight tubule (thick ascending limb) Distal convoluted tubule Collecting tubule Collecting duct
  16. 16. Filtering apparatus 1. Endothelium of glomerular capillaries 2. Glomerular basement membrane 3. Visceral layer of Bowman’s capsule 4. The slit membrane
  17. 17. Juxtaglomerular Apparatus found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. 1. Juxtaglomerular cell - secrete Renin (part of Renin Angiotensis system) 2. Mesangial cells - Chemoreceptors cell : ion concentration in blood 3. Macula Densa - senses any increase in the sodium chloride concentration in the distal tubule of the kidney
  18. 18. Cortical Nephron - 85% of Nephorn
  19. 19. Juxtamedullary Nephron - Henle loop longer than Cortical nephron - Renal corpuscle closer to medulla - Enabling excretion of dilute or concentrate urine - Vasa recta
  20. 20. Proximal Convoluted Tubule
  21. 21. Proximal straight tubule Descending Thin Tubule Ascending thin tubule Distal straight Tubule
  22. 22. Loop of Henle Location • In medulla Content • Descending tubule • Ascending tubule http://www.studyblue.com/notes/note/n/ph3-09-solute-and- water-movement/deck/1101248
  23. 23. Loop of Henle
  24. 24. Descending tubule http://www.lookfordiagnosis.com/mesh_info.php?term=Loop+Of+Henle&lang=1 Function • Reabsorption water Segment of tubule • Long thin tubule – Simple squamous epithelium • Short thick tubule – Simple low cuboidal epithelium
  25. 25. Ascending tubule http://www.lookfordiagnosis.com/mesh_info.php?term=Loop+Of+Henle&lang=1 Function • Reabsorption sodium Segment of tubule • Short thin tubule – Simple squamous epithelium • Long thick tubule – Simple low cuboidal epithelium
  26. 26. Thick & Thin segment
  27. 27. Thick & Thin segment
  28. 28. Distal convoluted tubule http://droualb.faculty.mjc.edu/Course%20Materials/Elementary%20Anatomy%20and%20Physiology%2050/Lec ture%20outlines/urinary_system.htm Location • In cortex Length • 1/3 as long as proximal tubule Epithelium • Simple cuboidal epithelium Function • Ion exchange
  29. 29. Distal convoluted tubule
  30. 30. Distal convoluted tubule http://www.siumed.edu/~dking2/crr/RN008b.htm
  31. 31. Medullary ray • “many tubules of straight tubule”
  32. 32. Medullary ray
  33. 33. Juxtaglomerular apparatus
  34. 34. Juxtaglomerular apparatus • –Juxtaglomerular cells –Macula densa –Extraglomerular mesangial cells
  35. 35. Juxtaglomerular apparatus • Juxtaglomerular cells • Smooth muscle • afferent arteriole • renin
  36. 36. Juxtaglomerular apparatus • Macula densa • distal tubule • renin paracrine activity salt concentration fluid volume distal tubule
  37. 37. Juxtaglomerular apparatus • Extraglomerular mesangial cells - Chemoreceptor cells - Secret erythropoietin
  38. 38. Juxtaglomerular apparatus • Mechanism Renin-angiotensin-aldosterone system - NaCl distal convolutated tubule - blood pressure
  39. 39. Collecting tubule/duct • Cortex medulla • Cell • Central nucleus • Simple cuboidal epithelium • minor calyx • ADH
  40. 40. Collecting tubule/duct
  41. 41. Collecting tubule/duct
  42. 42. Papilla
  43. 43. Nerve supply sympathetic • vasoconstriction of afferent • vasoconstriction of efferent
  44. 44. Ureter/Bladder • Mucosa : transitional epithelium • Lamina propria- dense irregular collagen fibers • Muscularis – smooth muscle layer Ureters : renal pelvis
  45. 45. Ureter
  46. 46. Urinary bladder
  47. 47. Urethra • Male : terminal duct urinary genital systems • Female : urinary system
  48. 48. 3 1. Prostatic urethra : transitional epithelium 2. Membranous urethra : stratified/pseudostratified columnar epithelium 3. Penile urethra : pseudostratified columnar epithelium stratified squamous epithelium • • Epithelium : transitional pseudostratified columnar stratified squamous
  49. 49. urethra

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