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The urinary system
 

The urinary system

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Histology of urinary system

Histology of urinary system

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    The urinary system The urinary system Presentation Transcript

    • Kidney Produce Ultrafiltate •Called Urine Urine Ureter Urinary bladder Urethra
    • Function •Osmoreguration •Remove metabolic waste
    • Endocrine function Erythropoietin - regurate erythropoietic in bone marrow Rennin - Control blood preesure Vitamin D – regurate balance calcium
    • General structure of kidney
    • Interior anatomy of kidney - Cortex 1. Convoluted par convoluta - Proximal and distal - Renal corpuscle - Interlobular a. v. - Afferent and efferent arteriole
    • 2. Straight par radiata - ascending and descending limbs of loob of henle straight tubule - Collecting duct Straight medullary rays
    • Medulla pyramid 2. Straight tube -Loop of henle -Vasa recta -Collecting duct
    • Devide 2 zone 1. Outer Zone - Mainly loop of henle Thick and Thin 2. Inner Zone renal pappila - loop of henle only thin - Cappillaries - vessel
    • vascurature
    • Nephron Type of nephron 1. Cortical 2. Juxtamedulla - Short-looped nephron - long thick segments , short thin segments - Long-looped nephron - short thick segments , long thin segments
    • Nephron
    • Nephron Consists of 1. Renal corpuscle 2. Renal tubule - filtration - resorption - secretion
    • Renal Corpuscle Consists of 1.Glomerulus 2.Bowman’s capsule - fenestrated capillary - fed by afferent arteriole and drains to efferent arteriole - double-walled epithelium capsule
    • Renal Corpuscle
    • Renal Tubule Proximal convoluted tubule Proximal straight tubule (thick descending limb) Thin descending limb Thin ascending limb Distal straight tubule (thick ascending limb) Distal convoluted tubule Collecting tubule Collecting duct
    • Filtering apparatus 1. Endothelium of glomerular capillaries 2. Glomerular basement membrane 3. Visceral layer of Bowman’s capsule 4. The slit membrane
    • Juxtaglomerular Apparatus found between the vascular pole of the renal corpuscle and the returning distal convoluted tubule of the same nephron. 1. Juxtaglomerular cell - secrete Renin (part of Renin Angiotensis system) 2. Mesangial cells - Chemoreceptors cell : ion concentration in blood 3. Macula Densa - senses any increase in the sodium chloride concentration in the distal tubule of the kidney
    • Cortical Nephron - 85% of Nephorn
    • Juxtamedullary Nephron - Henle loop longer than Cortical nephron - Renal corpuscle closer to medulla - Enabling excretion of dilute or concentrate urine - Vasa recta
    • Proximal Convoluted Tubule
    • Proximal straight tubule Descending Thin Tubule Ascending thin tubule Distal straight Tubule
    • Loop of Henle Location • In medulla Content • Descending tubule • Ascending tubule http://www.studyblue.com/notes/note/n/ph3-09-solute-and- water-movement/deck/1101248
    • Loop of Henle
    • Descending tubule http://www.lookfordiagnosis.com/mesh_info.php?term=Loop+Of+Henle&lang=1 Function • Reabsorption water Segment of tubule • Long thin tubule – Simple squamous epithelium • Short thick tubule – Simple low cuboidal epithelium
    • Ascending tubule http://www.lookfordiagnosis.com/mesh_info.php?term=Loop+Of+Henle&lang=1 Function • Reabsorption sodium Segment of tubule • Short thin tubule – Simple squamous epithelium • Long thick tubule – Simple low cuboidal epithelium
    • Thick & Thin segment
    • Thick & Thin segment
    • Distal convoluted tubule http://droualb.faculty.mjc.edu/Course%20Materials/Elementary%20Anatomy%20and%20Physiology%2050/Lec ture%20outlines/urinary_system.htm Location • In cortex Length • 1/3 as long as proximal tubule Epithelium • Simple cuboidal epithelium Function • Ion exchange
    • Distal convoluted tubule
    • Distal convoluted tubule http://www.siumed.edu/~dking2/crr/RN008b.htm
    • Medullary ray • “many tubules of straight tubule”
    • Medullary ray
    • Juxtaglomerular apparatus
    • Juxtaglomerular apparatus • –Juxtaglomerular cells –Macula densa –Extraglomerular mesangial cells
    • Juxtaglomerular apparatus • Juxtaglomerular cells • Smooth muscle • afferent arteriole • renin
    • Juxtaglomerular apparatus • Macula densa • distal tubule • renin paracrine activity salt concentration fluid volume distal tubule
    • Juxtaglomerular apparatus • Extraglomerular mesangial cells - Chemoreceptor cells - Secret erythropoietin
    • Juxtaglomerular apparatus • Mechanism Renin-angiotensin-aldosterone system - NaCl distal convolutated tubule - blood pressure
    • Collecting tubule/duct • Cortex medulla • Cell • Central nucleus • Simple cuboidal epithelium • minor calyx • ADH
    • Collecting tubule/duct
    • Collecting tubule/duct
    • Papilla
    • Nerve supply sympathetic • vasoconstriction of afferent • vasoconstriction of efferent
    • Ureter/Bladder • Mucosa : transitional epithelium • Lamina propria- dense irregular collagen fibers • Muscularis – smooth muscle layer Ureters : renal pelvis
    • Ureter
    • Urinary bladder
    • Urethra • Male : terminal duct urinary genital systems • Female : urinary system
    • 3 1. Prostatic urethra : transitional epithelium 2. Membranous urethra : stratified/pseudostratified columnar epithelium 3. Penile urethra : pseudostratified columnar epithelium stratified squamous epithelium • • Epithelium : transitional pseudostratified columnar stratified squamous
    • urethra