What is happening inside our craniums, amongst the cortex, hemispheres, neuroglia, and brainwaves when we feel on fire with creativity and when we don't? To find out, let’s embark upon a fantastic journey to learn in which circumstances and states the brain is most creative. At the end, we'll better understand the brain on creativity and discover unconventional methods to leverage its power for increased ideation, inspiration, innovation, and flow. Beware: the science of the creative brain challenges the standard norms around concentration, focus, productivity, and may change how you work. Presented at SXSW Interactive, 2013