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MODULE 1: DEVELOPMENT
MODULE 2: NEUROANATOMY
MODULE 3: LESIONS
MODULE 1:
DEVELOPMENT
SEGMENT 1: BIRTH OF
THE NERVOUS SYSTEM
Karaman, Ali MD; & Aliagaoglu, Cihangir MD. (2003). Waardenburg
syndrome type 1. Dermatology Online Journal, 12(3). Retrieved from:
https://escholarship.org/uc/item/0r5371ck
Waardenburg syndrome:
a neural crest disease
MODULE 1: DEVELOPMENT
SEGMENT 2: NEURAL TUBE
FORMATION
http://en.wikipedia.org/wiki/Spina_bifida
Spina bifida:
NTD of the posterior neuropore
http://commons.wikimedia.org/wiki/File:Anencephaly_side.jpg
Anencephaly:
NTD of the anterior neuropore
http://www.anencephalie-info.org/e/report.php
Anencephaly is lethal
Die before birth
Die during birth
Live for <1 hr
Live for 1-24 hrs
MODULE 1: DEVELOPMENT
SEGMENT 3: BRAIN
DEVELOPMENT
Häggström, Mikael. "Medical gallery of Mikael Häggström 2014". Wikiversity
Journal of Medicine 1 (2). DOI:10.15347/wjm/2014.008. ISSN 20018762
MODULE 2:
NEUROANATOMY
SEGMENT 1: AUTONOMIC
NERVOUS SYSTEM
MODULE 2:
NEUROANATOMY
SEGMENT 2: NERVES
MODULE 2:
NEUROANATOMY
SEGMENT 3: CNS REGIONAL
FUNCTIONS
MODULE 2:
NEUROANATOMY
SEGMENT 4: LONG CNS
PATHWAYS
CORTICOSPINAL TRACT
Species # of fibers
Human 1,100,000
Macaque 554,000
Cat 186,000
Mouse 32,000
Free-tail bat 8,000
MODULE 2:
NEUROANATOMY
SEGMENT 5: HEMISPHERE
FUNCTIONS
BROCA’S PATIENTS
• Leborgne: “tan, tan”
• Lelong: “oui”, “non”, “tois [trois]”,
“toujours” “Lelo [Lelong]”
POEM WRITTEN ABOUT APHASIA
do not SORRY me
surprize to alive
I coodov died
body OK not parrallize
night please NOT askme
answer questions
night depresst night I cry
I’m OK right? except simbol
cant come out mouth
inspeech
hoPital hopisal hopital
deprext deppressed
afixit aFAZic
cant see these mylips
Watteau—
Watteau clown
I hate Watteau
askfor magicmarkers
I draw flag out hopistal window
wood WAV
if I cood SKIL stil inhand
MODULE 3: LESIONS
SEGMENT 1: OXYGEN
AND CEREBRAL
BLOOD FLOW
Sea level Top of Mt Everest
Everywhere except the cranium
perfusion pressure =
arterial pressure – venous pressure
Brain
cerebral perfusion pressure =
arterial pressure – intracranial pressure
ICP = 15 mmHg
VP = ~5 mmHg
MODULE 3: LESIONS
SEGMENT 2: BLOOD SUPPLY
MODULE 3: LESIONS
SEGMENT 3: STROKES &
TUMORS
Renee-Nicole Douceur, the winter
manager at the Amundsen-Scott
research station at the South Pole,
was sitting at her desk on August
27:
'I looked at the screen and was
like, "Oh my God, half the screen is
missing.”’
http://beta.slashdot.org/story/158954
MODULE 3: LESIONS
SEGMENT 4: BLEEDS
http://www.apspjcaserep.com/documents/2010-1/ajcr-2010-1-21.html
Encephalocele:
NTD of the anterior neuropore

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