carrier in chemistry

1. SCOPEOF
CHEMISTRY
AFTER B.Sc.
1

2. Chemistry is that physical science which
includes the study of a range of matters
such as atoms, crystals, molecules and
many other collections of matters
whether they are in isolation or in
combination.
2

3. 3

4.  Some of the higher study options after B.Sc
Chemistry are
-M.Sc. Chemistry
-M.Sc.Analytical Chemistry
-M.Sc. Drug Chemistry
-M.Sc. Organic Pharmaceutical Chemistry
-M.Sc. Physical &Materials Chemistry
- M.Sc. By Research
-Master of BusinessAdministration (MBA)
- Ph.D in Chemistry
Scope for Higher Studies after
B.Sc Chemistry
4

5.  Analytical Chemist
 Biomedical Chemist
 Production Officer Quality Controller
 Associate Industrial Research Scientist
 Lab Chemist
 Materials Technologist
 Production Chemist
 Chemical Engineering
 R&D Director
 Research & Development Manager
 Safety Health And Environment Specialist
 Teacher 5

6. The employment areas for the B.Sc
Chemistry graduates include
pharmaceutical industries, chemical
manufacturers, Forensic Science
Department, plastic industries,
agrochemical industries, etc. Apart from
these, they are also recruited in other fields
such as oil, gas and power sectors and
even in defence services.
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7. TOPPh.D. Institutes in India.
 National Chemical Laboratory , Pune
 IISER, Pune
 IISER, Bhopal
 National Institute of Chemical Technology, Hyderabad.
 Indian Institute of Science , Bangalore
 IIT , Bombay
 IIT , Chennai
 IIT, Kanpur
 Institute of Chemical Technology , Mumbai.
 Research Institutes affiliated to University.
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8. Government Jobs in Chemistry
• UPSC www.upsconline .nic.in
• MPSC www.mpsconline .gov.in
• Forensic recruitment , Lecturer for gov Colleges
for NET & Non NET candidates.
• ONGC www.ongcindia.com form are
continuethrough our the year.
• NTPC www. Ntpccareers.net Various post in
NTPC.
• Geoscientist post for Chemistry and Lecturer post.
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9. SCOPE, Other Than Traditional :-
• Scientist, Science communicator
• Substantiality Manager.
• Fragrance Chemist.
• Favourist & innovation Director
• Application Chemist
• Organic Skincare & Cosmetic Range
• Substantiality Consultant
• Environmental Chemist.
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10. Indian ChemicalIndustry
1
Indian Chemical Industry plays a major role in the overall
development of India
Contributes significantly to India’s economy under
manufacturing sector
It accounts for approximately 7% of India’sGDP.
Output value in the year 2012-13 was 782,949crores
Indian chemical Industry is 6thin the world and 3rdinAsia
India’s exports of chemicals (excluding pharma) was 32.02
US$billion in 2013, and imports US$46.01
Chemical industry growth rate of over 8-11% p.a.and
expected to reach $290billion by 2017

11. Chemicalindustries- Category
1
The chemical industries broadly categorised;
Basic inorganic & Organic chemicals
Specialty chemicals & fine chemicals
Petrochemicals & plastics,
Pesticides & Agrochemicals,
Fertilizers
Dyes & pigments
Paints & varnishes,
Soaps, perfumes & toiletries and
Pharmaceuticals and others

12. IndianPharmaceutical industry- overview.
1
Indian pharmaceutical industry is growing fast as
like IT industry.
Manufactures Quality Medicines at affordable cost.
Significant growth is from 1990’s
Market size is about 2 lakhscrore
It is 3rdlargest in the world by volume (10%) and13th
largest (~ 3%) inthe world in term of value.
Growing at around 15-20% (6-8% in global).
Expected grow and reach US$100 billion by2025.

13. Indian Pharmaceutical industry
1
More than 90% of drugs used in India are
produced in India
The industry is quite fragmented and comprises of
nearly 10,500 companies and majority of them in
the small sector.
Around 300-400 are organized companies
categorized as medium & large
Direct employment is 5lacs and total
employment could be over 20lacs
Mostly located in Maharashtra, Gujarat,
Telungana , AP, HP, Tamil nadu.

14. * AmongfastestgrowingIndustries:The IPI(Indian
Pharmaceutical Industry) revenue is expected to
expand at a CAGRof 17.8 % during 2008-16 andreach
USD36 billion
* Rapidgrowinghealthcare sector:By 2015, the
healthcare sector is expected to reach USD100 billion
from the current USD65billion.
* GrowingGenericMarket:The generic market is
expected to grow to USD26.1 Billion by 2016 from
current USD11.3 billion in 2011; India genericsMarket
has immense potential for growth
th
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15. Export Indian PharmaIndustry
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India competing with developed countries
due to lower manufacturing cost with better
Quality.
India import was huge and higher than the
export until late 1980s,
Since 1990 export starts growing ,now
export is 5 times higher thanimport.
Export is 50% of the total turnover.
Exported to >200 countries for both
developed and developing countries.
Around 25% of export is toUSA.
20% of the total volume of global generics
ie 1 in 5of Generic * is from India.
*Genericmedicines, andto low-cost versions of newly-developed medicines

16. Highlightsof Indian Pharma Industry
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In 2001, CIPLAwas in limelight, offered an AIDSdrug to for
the price of $300 against $12,000 inUS.
India manufactures 30% of the world requirement ofAnti-
HIVdrugs
key contributor to the WHOPrequalification Programme
(PQP) 65-70%
AIDS,Tuberculosis, Malaria, Reproductive Health, and etc...
2012, NATCOgot approval to sell kidney-cancer drug
Nexavar at 3% of market price under compulsorylicense.
CostRs.8500against Rs.2.8 lakh

17. Advantageof Indian Pharma Industries
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Global consumption of :The USaccounts for 40-45%, EUis about 20-
24% and Japan15%; balance is rest of world
So target market is US,EU& BRICS.
India is the highest USDMFapproved country outside theUS
India accounts for 30.3 per cent (2,911) of 9619 Drug Master Files
(DMFs) filed with USA,which is the highest outside of USA.
584 manufacturing sites approved by USFDAand next is Italy (<200)
Several Indian Pharmaceutical companies set up plants in abroad
Fast growth in R&Dactivities.

18. SS The effects in new product patent
SS Price control in the drugs
SS Reformation in the regulatory
SS Developments in the infrastructure
SS Quality Management concept
SS Conforming the global standards
The other challenges include:
* Decline in the production
* Reducer in Drug Approvals
* Stringent regulations
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19. GrowthPotential: Opportunity
19
Indian Pharma industry posses several strengths;
Innovation and process design- to copy cat generic.
Strong R&Dcapability,
Qualified personnel
Abundant skilled man power
Around 270 large R& Dbased pharma companies in
India.
Past track is capable of producing better quality drugs
with lower manufacturing cost.
Knowledgeable and Skilled man power (Research,
analytical, regulatory, clinical and IT)

20. Research& Development:
20
Indian Pharma companies spent huge amount for R&D.
Dr.Reddy’s, SunPharma, Gleanmark are investing in
discovery research
Several companies involved in process development and
contract research.
US$300bn worth of Patent drugs expiries by 2017.
Global R&Dcost is estimated as USD65bn
Contract Research

21. TopIndian Pharmaceutical companies
1. Sun Pharma
2. Dr. Reddy's Labs
3. Cipla
4. GSK
5. Strides
6. Lupin
7. Aurabindo
8. Wockhardt
9. Zydas Cadila
10. NATCO
11. Orchid
12. IPCA
13. Biocon
14. Torrent
15. Shasun
16. Alambic etc
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22. WorldT
opPharma Companies
22
Company Sales R&DExpense
1. Novartis $57,996 ($9946)
2. Pfizer $45,708 $8,393
3. Sanofi $41,047 $5,863
4. Roche $37,082 $9,006
5. Merck $36,042 $7,180
6. Johnson & Johnson $32,313 $6,213
7. GlaxoSmithKline $30,806 $5,693
8. AstraZeneca $26,095 $5,579
9. Gilead Sciences $24,890 $2,854
10. Teva $20,272 $1,488
Basedon 2014 Sales, in $U.S.Millions
Ref:Contract pharma

23. Money spentfor healthcare
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24. 8 – 12 years
Drug Discovery is becoming more time and cost consuming…
Drug discovery process :
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25. Clinicalstudy:
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Aclinical trial is a tool for testing a drug,
medical device, or technique for safety
and efficacy.
Global clinical trial market is ~USD 60bn.
Money involved for new drug min is USD
600-mn 2bn out of this 150-200mn spent
for clinical trials
India will make it with 50-60% of cost
and faster.
The advantages are, technical resources
(physician, nurses, and other technical
personals), having developed IT
infrastructure, protection on IPRrelated
issues and etc.

26. JobOpportunities
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Pharma is knowledge based industry
Special skills are required to work
Offers excellent salary ,benefits & scope for growth.
Jobopportunities for Chemistry / pharmacy
graduates / pharmaceutical Technology/ Doctors
Government & private sector

27. JobOpportunities
 Government& Public sector:
 State & Central Govt
 Public sector
 National Labs
 Drug testing
 Research & Development
 NIPER,CSIR, CDRL
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28. JobOpportunities in PharmaIndustry
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Functions/Aactivities :
Marketing & Sales –Technical
Manufacturing/production
Environment management
Research & Development
Quality control & Quality assurance
Regulatory Affairs & IPR
Clinical trials
Testing laboratories- private

29. Manufacturing/production:
29
Knowledge & Skill required:
Process Chemistry
Technology transfer
Chemical reaction
Handling of Chemicals
Unit operations
Reaction, distillation,
filtration, drying, blending
Formulation, etc

30. Research&
Development
30
Knowledge & Skill required:
Synthesis- all kind of organic
reaction
Process chemistry
Thermo chemistry
Kinetics
Structure elucidation
Patent search
New analytical techniques
Simple & easy test methods

31. QualityAssurance& Regulatory
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Quality Assurance & Regulatory functions
Pharma industries governed by stringent Rules&
regulations
Drugs & Cosmetic Act
Quality system
Good Manufacturing Practice (GMP)
Documents for each activities
Rules & Regulations as per exporting countries
Regulatory Inspection and approvals

32. Testing/Quality Control
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Knowledge & Skill required for QCfunctions

33. Analytical technique
Chromatography
Spectrophotometry
Chiral testing- Optical rotation
Particle size
Dissolution
Inorganic impurity -Residue on
ignition
Crystal structure- XRD
Thermal properties - TGA/ DSC-
Melting point
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34. Simpleinstruments for testing
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pH meter
Conductivity meter
Polarimeter
Refractometer
Titrator
Particle size
Dissolution apparatus
Etc…

35. Spectroscopy
35
Theory, instrumentation and application
UV-Visible spectrophotometer
FT-IR Spectrum
Mass spectrophotometer
NMR
AAS/ ICP-AESor OES
XRD

36. Chromatography
36
Extensively used technique is
Chromatography for testing
of purity and impurity in
complex molecule;
TLC
Gas Chromatography
HPLC
Gel permeation
Ion chromatography

37. T
esting
37
Drugs are tested for :
Purity
Impurities
Structure confirmation –IR,UV
Specific rotation
Loss on drying/ water
Residue of Ignition(inorganic)
Dissolution
Drug release
Stability

38. RegulatoryAffairs
38
Technical writing
Rules & regulation of various countries
Basic chemistry
Basics of Process & testing
Computer knowledge & communication

39. Preparedness
39
Over 15 years, employment potential couldrange
between 8-9 million jobs.
Education & training
Instrumentation course
Diploma in pharmaceutical course
Personal development
Interview skill

40. Reference:
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Annual report 2014-15 & Chemicals & petrochemicals statistics AT AGLANCE:
2014 govt of india, ministry of chemicals &fertilizers
INDIANCHEMICALINDUSTRY:Five year plan –2012-2017
The pharmaceutical industry and Global health facts and Figures 2014: IFPMA
India Pharma summit 2014-15 position paper; dept of pharmaceuticals, govt of
india
India Chem 2014 :Spurting the growth of Indian Chemical Industry: FICCI
ABrief report of Indian pharmaceutical industry InIndia- ASA Associates
India PharmaInc.Gearing up for the next level of growth PWC
Fromvisionto decisionPharma 2020- PWC
Profile of pharmaceutical industry- Chapter –iv
Wikipedia