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2. Z i n g i b e r e n e
Zingiberene is one of the turmerone-type compounds found in the root, essential oil
from turmeric's rhizome, and dried rhizome.
This compound belongs to the class of organic compounds known as
sesquiterpenoids. These are terpenes with three consecutive isoprene units..
• Top plants containing Zingiberene
1. Curcuma longa
found in Root, Rhizome Essent. Oil, Rhizome
2. Zingiber officinale
found in Rhizome, Root Essent. Oil, Essential Oil, Rhizome Essent Oil.
3. Salvia canariensis
found in Leaf
4. Aralia cordata
found in Root
5. Angelica archangelica
found in Root

3. • Chemical Structure
Chemical formula
C15H24

4. Medicinal value (uses)
According to research studies, zingiberene has the following
properties and may be able to:
1.
2. Antioxidant.
3.
4. Anti-inflammatory , Anti-tumour and Anti-microbial.
5.
6. Help fight infections caused by viruses.
7.
8. Protect against stomach ulcers.
9.
10.Cell signaling.
11.
12.Fuel and energy storage.
13.
14.Fuel or energy source.
15.
16.Membrane integrity/stability.
17.
18.Nutrient.

5. zingiberene synthesis
Zingiberene synthase is an enzyme found in ginger rhizomes
(Zingiber officinale). It converts farnesyl diphosphate into
zingiberene and diphosphate in a single enzymatic reaction.

6. Side effects
• In small doses, Zingiberene has few side effects.
•
1. Heartburn
2. Upset stomach
3. Mouth irritation
• High doses of Zingiberene -- more than 5 grams a day -- increase the chances of
side effects. Zingiberene on the skin may cause a rash.
Risks
Zingiberene may raise the risk of bleeding. If you have a bleeding
disorder, it may not be safe. Always tell your doctor about herbal
medicines you take, including Zingiberene

7. Precautions
• Not to be used when there is excess heat in the stomach, as in
peptic ulceration. ginger will aggravate the situation.
•
• Use in moderation for morning sickness.
•
• ginger reduces blood clotting. If you are taking anti-coagulant drugs,
such as warfarin sodium, or are preparing for surgery, consult
with your naturopath or other health practitioner before taking
ginger.
•
• ginger herb may also raise blood pressure levels in some
individuals

8. Qualitative and quantitative
Chemical Tests
Determination of Volatile Components in Ginger Using Gas Chromatography−Mass
Spectrometry with Resolution Improved by Data Processing Techniques
Zingiberene retention time : 14.02

9. Summary
1. What is the type of Zingiberene and where can we find it ?
2.
3.Mention some natural sources containing Zingiberene.
4.
5.What is the chemical structure of Zingiberene
6.
7.Talkabout medicinal value of Zingiberene
8.
9.Draw the synthesis equation of Zingiberene
10.
11.Mention some side effects of Zingiberene
12.
13.What are the risks and Precautions of taking Zingiberene
14.
15.What is the retention time of Zingiberene in hblc

10. Summary
1. What is the type of Zingiberene and where can we find it ?
2.
3.Mention some natural sources containing Zingiberene.
4.
5.What is the chemical structure of Zingiberene
6.
7.Talkabout medicinal value of Zingiberene
8.
9.Draw the synthesis equation of Zingiberene
10.
11.Mention some side effects of Zingiberene
12.
13.What are the risks and Precautions of taking Zingiberene
14.
15.What is the retention time of Zingiberene in hblc