The document describes ComRAD, an intelligent information and expert system for the healthcare domain. ComRAD provides medical specialists with advice for optimal treatment decisions. It consists of a Universal Knowledge Base (UKB), Operating Data Base (ODB), and CoSMoS managing and design software. The ODB contains patients' electronic health records while the UKB contains medical science information and resources. CoSMoS utilizes algorithms to generate forms, design treatment variants, and enable intrasystem communication between components. ComRAD aims to provide optimal, personalized treatment recommendations based on all relevant scientific and patient-specific factors.

1. e-TOOL FOR APPLICATION IN COMPUTERIZED RECOVERY ADVISOR ComRAD HEALTH CARE

2. ComRAD Chart UKB CoSMoS Medical Treatment Advisory Information ComRAD Clinical, Research for Medical knowledge ODB Patient ANAMNESIS General Practitioner Case Information Treatment Information General Practitioner EHR Clinical Laboratory Tests X-Ray MRI, CT Scan Blood Test, etc. Request Test Result Tests Results Patient Health History

3. Computerized Recovery Advisor - ComRAD© & ANAMNESIS© SINGLE SYSTEM SERVER First visit Prescriptions 5 4 MS optimal decision 1. Lab Results Patient Next visit 1 . Lab Results 2 . Advice Monitoring 3 SINGLE SYSTEM SERVER UKB – Universal Knowledge Base© contains: a). Medical Science Information, - all factors has to be taking into account in optimal medical treatment design; b). Resources for testing & examination c.) Resources for treatment ODB – Operating Data Base contains Electronic Health Records (EHR) with complete secure patient’s data. CoSMoS – Managing and Designing Program GP – General Practitioner. Anamnesis – Test for definition of a Patient’s body systems that require immediately attention. First visit: before visit a patient use an Anamnesis to provide GP with information which patient’s body system require immediately attention and what testes and examinations has to be done. Next visit: after getting results of tests and examinations, system provides GP with several sub optimal variants of medical treatments. GP selects the best one (optimal variant). Server with a Variable Logic Processor – Monitoring will be done with a Pulse-Medic-Analytics device, for control patient’s pulse, blood pressure, sugar level. 3 4 1 4 5 . Refer to Lab GP ODB Patient Anamnesis Monitoring SCIENCE CoSMoS UKB© LAB DRAG LAB

5.  a decision support system that provides medical specialists with advises for the optimal decision making.  presented as ..  a unified system integrated with a lab (includes diagnostic devices), pharmaceutical, office assistance and other systems with complete interoperability between them by the intersystem software. ComRAD© ( Computerized Recovery Advisor ) also is:

10. ComRAD KB AS A PART OF UNIVERSAL KB C SCIENCE User’s Portal 1. Interactive process of filling professional (scientific and standard) information to the UKB using computerized Systems Analysis 3. Interactive process of getting and filling necessary information from/ to Patient’s file in ODB 4. Population of new information to the KB as results of practical experience and scientific research 2. Query and Generation of a necessary professional & standard related to the case (specific Forms) from the KB 2 3 4 4 Developers 1 2 ComRAD ODB AS A PART OF REGION ODB

17. ComRAD KB

18. ComRAD KB

19. ComRAD KB

21. Pre-diagnostic test – ANAMNESIS© Presented by: Alliance of Technology and Science Specialists of Toronto Inc. and Design of Intelligent Systems Knowledge Co. ═════════════════════════════════════════════════ T E S T V.1 _____________________________________________________ ║ SYSTEMS MIGHT NEEDS SUPPORT ║ ---------------------------- ║ Circulatory 17 ║ Digestive 16 ║ Urinary 15 ║ Structural 14 ║ Glandular 13 ║ Immune 11 ║ SYSTEMS PROBABLY DOESN'T NEEDS SUPPORT ║ --------------------------------------- ║ Intestinal 8 ║ Nervous 7 ║ Respiratory 4 Do you want printing result ? (y/n)

24. ComRAD Specification Continued… TO LOWER LEVEL FROM SCIENCE FROM UPPER LEVEL KB LEVEL: ORGANS STRUCTURAL MODEL OF ORGANS FROM UPPER LEVER FUNCTIONAL MODEL OF ORGANS TO LOWER LEVEL COMPARISON CURRENT HEALTH CHARACTERISTICS NORMS ODB FROM UPPER LEVER

26. Symptoms/F-1HC John Smith Mr. Birthday: 03/24/1965 Health History F-HH Date: 07/04/2007 Date: 04/16/2007 Statistic FD-5HS Patient’s Personal Data Patient’s Family Data Doctor’s ID Examinations by Lab/F-2HC Examinations by Devices /F-2HC Recommendations/F-3HC Consultations/F-4HC Results of Consultations/F-4HC Prescriptions/F-3HC Office Statistic/FD-1HO Images

27. CASE EXAMPLE Patient’s Complains Fever 39 °C Respiration cough out Respiration noise Respiration cough Headache strong … . …. Tests & Exams Antibiotic T 3p/day Tylenol Cold/ Night 1p/day Liquid A 2c/day Vitamin C 1000 mGr/day Tea A lot Prescriptions ComRAD KB 39 °C in the morning cough out difficult noise breathing permanent cough often Headache strong Permanent Mucus green Anamnesis ComRAD KB Natural Habitat … … .. Professional Data … … .. Personal Data … … .. Life style … … .. Body Systems … … .. ComRAD KB Normal characteristics Temperature 37 °C Breathing Cough out in the morning Breathing no noise Breathing no cough Breathing cough Headache Middle … . … . crepitating Respiration X-Ray 60/sec Pulse 90/140 Blood Pressure Mucus