1). The gene CSF2RA codes for colony stimulating factor 2 receptor a.pdf

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1). The gene CSF2RA codes for colony stimulating factor 2 receptor alpha subunit. The function of this protein is to control production, differentiation, and functioning of immune cells (macrophages and granulocytes). It is a maternally inherited gene. 2). The CD99 gene codes for cluster differentiation 99 protein. It is a glycoprotein involved in the regulation of adhesion of T-cells and death of T-cells by a caspase-independent pathway and migration of leukocytes. This is inherited from both the X-chromosome and Y-chromosome. 3). The CRLF2 gene codes for the protein Cytokine Receptor-Like Factor 2. It acts as a receptor for thymic stromal lymphopoietin (TSLP). In association with the interleukin 7 receptor, this protein activates STAT3 pathway, STAT5 pathway and JAK2 pathways, which regulate the process of haematopoiesis. 4). SRY (Sex Determining Region Y) gene encodes a protein known as Sex-determining Region Y protein. This protein determines the development of sexual characteristics in a fetus. SRY gene is present on Y chromosome. SRY protein controls the expression of particular genes and triggers the process of male gonads development. Thus, this process inhibits the development of female gonads and female reproductive structures while promoting the development of male reproductive structures. Solution 1). The gene CSF2RA codes for colony stimulating factor 2 receptor alpha subunit. The function of this protein is to control production, differentiation, and functioning of immune cells (macrophages and granulocytes). It is a maternally inherited gene. 2). The CD99 gene codes for cluster differentiation 99 protein. It is a glycoprotein involved in the regulation of adhesion of T-cells and death of T-cells by a caspase-independent pathway and migration of leukocytes. This is inherited from both the X-chromosome and Y-chromosome. 3). The CRLF2 gene codes for the protein Cytokine Receptor-Like Factor 2. It acts as a receptor for thymic stromal lymphopoietin (TSLP). In association with the interleukin 7 receptor, this protein activates STAT3 pathway, STAT5 pathway and JAK2 pathways, which regulate the process of haematopoiesis. 4). SRY (Sex Determining Region Y) gene encodes a protein known as Sex-determining Region Y protein. This protein determines the development of sexual characteristics in a fetus. SRY gene is present on Y chromosome. SRY protein controls the expression of particular genes and triggers the process of male gonads development. Thus, this process inhibits the development of female gonads and female reproductive structures while promoting the development of male reproductive structures..

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Distinguish between cell fate and cell commitment. How can one assay these aspects of cellular phenotype by experimental embryology? Solution Cell fate--It means the development of the cell into an embryo and the events which govern the development of the egg cell throught the process of embryogenesis.The factors which determine the cell fate include cell signaling pathways like notch pathway etc, regulation and control by pathways like mRNA,siRNA inside the cell,development of different cavity inside the embryo, development of ectoderm,mesoderm and endoderm, and the regulation of cell fate determination by release of various controlling hormones. cell commitment--it involves the orientation and decision by the cell to undergo differentiation and follow a particular developmental pathway.It involves the release of various growth promoting factors by stem cells which lead to the differentiation of stem cells into mature cells by triggering and activating a particular organ development pathway example--blood cells. There are several aspects of determination of the cellular phenotype by experimental embryology----1)sex determination pathways in insects and dosage compensation 2)regulation of different genes in different climates,temperature, and background environment determines the activation and inhibition of development genes in caterpillar larvae of insects3) the division of fertilized egg into morula, blastula, gastrula ,and development of different layers by cell regulatory protein factors 4)role of cell adhesion protein molecules during cell differentiation pathway 5)development of cell symmetry and asymmetry of the insects 6)development of embryo cavity and germline layers of development after fertilization 6)development of cells to tissues to organs with the help of secreting chemicals, protein factors and hormones which activate the differentiation pathway..

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To insert value X into a B-tree, there are 3 steps: If there are M nodes after adding X, we say the node has overflowed. To repair this, we split the node into three parts: Left: the first (M-1)/2 values Middle: the middle value (position 1+((M-1)/2) Right: the last (M-1)/2 values Notice that Left and Right have just enough values to be made into individual nodes. That\'s what we do... they become the left and right children of Middle, which we add in the appropriate place in this node\'s parent. But what if there is no room in the parent? If it overflows we do the same thing again: split it into Left-Middle-Right, make Left and Right into new nodes and add Middle (with Left and Right as its children) to the node above. We continue doing this until no overflow occurs, or until the root itself overflows. If the root overflows, we split it, as usual, and create a new root node with Middle as its only value and Left and Right as its children (as usual). Solution To insert value X into a B-tree, there are 3 steps: If there are M nodes after adding X, we say the node has overflowed. To repair this, we split the node into three parts: Left: the first (M-1)/2 values Middle: the middle value (position 1+((M-1)/2) Right: the last (M-1)/2 values Notice that Left and Right have just enough values to be made into individual nodes. That\'s what we do... they become the left and right children of Middle, which we add in the appropriate place in this node\'s parent. But what if there is no room in the parent? If it overflows we do the same thing again: split it into Left-Middle-Right, make Left and Right into new nodes and add Middle (with Left and Right as its children) to the node above. We continue doing this until no overflow occurs, or until the root itself overflows. If the root overflows, we split it, as usual, and create a new root node with Middle as its only value and Left and Right as its children (as usual)..

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The physical protection of knowledge, assets and personnel is key to any security system. Closely associated with physical security ar the technical security safeguards needed to guard sure facilities against intelligence assortment or observation and security procedures adopted to observe and management physical access to facilities and material. Government rules for {cover|for defense} of classified info cover construction and storage necessities (facilities, locks, alarms, guards), technical security necessities obligatory on facilities storing classified info (surveillance countermeasures, TEMPEST, audio attenuation), and procedures moving the conduct of operations at intervals these facilities (inspections, document management, visit certification, and badges). The Commission\'s focus was totally on the domestic setting wherever there\'s the best potential for value savings, a lower level of threat, and since it lends itself additional without delay to uniformity than do facilities at overseas locations. Our review was restricted to the protection of classified info and material. It didn\'t embrace protection of weapons, munitions, or nuclear devices that ar ruled by separate rules. Recently there are important policy changes moving physical security at intervals the intelligence service. However, it seems that cross-program management for physical, technical, and procedural security countermeasures isn\'t uniform. The relationships with industrial contractors vary from relatiative compliance inspections to problem-solving recommendation and help. additionally, several of our physical security policies ar out of date, don\'t seem to be supported actual threat, conflict with one another, and haven\'t been enforced in an exceedingly uniform fashion. As a result, the top user is moon-faced with a patchwork of multiple standards, exaggerated prices as a result of facilities can\'t be shared, and irrational things wherever info classified at a lower level (Confidential and Secret) is usually additional strictly protected than our government\'s most sensitive technologies and operations. The large choice of physical, technical and procedural security necessities obligatory on trade is that the principal concern that cause the event of the National Industrial Security Program (NISP). For Confidential and Secret info, the Defense Industrial Security Program needs that contractors be inspected each six months, that guards physically check safes that hold classified material, which tight document management audits and inventories be maintained. Director of Central Intelligence representatives ordinarily examine facilities housing Sensitive compartmentalized info once each 2 years, need alarms instead of valuable guards, and recently have born strict document handling necessities. The Commission seeks to use physical, technical, and procedural security in line with a similar basic risk management principles suggested throughout this report. Securit.

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Purpose of cashflow statements are to analyse the different cashflows generated by the firm(hospital) into a) Operating cashflows: The cashflows(inflows/outflows) from operating activities of the hospital i.e providing services to patients from consulting, scanning, nursing and so on. b) Financing activities: Inflows/outflows which involve in raising funds to run the hospitals, meeting debt obligations c) Investing activities: Involves in where/what assets the hospital is investing into to generate the required operating cashflows. The cashflow statements are not only important to the hospitals but generally in US as well to get a right sense of understanding as to how the cashflows received are actually been utilised in the business and which cashflows actually do not belong to the daily operations of the business being run. Solution Purpose of cashflow statements are to analyse the different cashflows generated by the firm(hospital) into a) Operating cashflows: The cashflows(inflows/outflows) from operating activities of the hospital i.e providing services to patients from consulting, scanning, nursing and so on. b) Financing activities: Inflows/outflows which involve in raising funds to run the hospitals, meeting debt obligations c) Investing activities: Involves in where/what assets the hospital is investing into to generate the required operating cashflows. The cashflow statements are not only important to the hospitals but generally in US as well to get a right sense of understanding as to how the cashflows received are actually been utilised in the business and which cashflows actually do not belong to the daily operations of the business being run..

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Modern Times is one of the greatest movies in the history of film. The protogonist clearly depictts the poverty,struggle after the great depression times and how industrial age destroy the lives of the small employees. The assembly line of henry ford may have increased productivity but the employees are merged with the machinery as if they are blind machines.Every where chaplin go, the situation would be that he has to battle with the crowds for his livelihood or self respect. He clearly portrays the pain of being a small cog in the company which exploits its employees.He shows how america\'s race for automation have made life horrible for the employees when the company thinks that allowing employees a lunch break is wasting time. After getting cure from his nervous break down when he attempts to lift a fallen red flag, communists mistake him for their leader and he was jailed for starting a revolution. My opinion is that people under severe poverty and pain are waiting for a saviour and are ready to see in all directions to catch a break from the wretched life.This can give rise to leaders who can manipulate the crowds for their own benefit as we have seen in the history of the 19th century. After some scenes, chaplin observes that the best place to land is in jail itself and tries to get jailed. I saw this as normal person\'s inner thought where if he just stop complaining and stay calm he can be happy instead of raising his voice and expecting something of the wretched system which is depicted in the movie. When all said and done the final scene when he says no matter what we keep being happy and walk into the unknown future hoping for the better then i think chaplin would like to say that no matter what the situation is a person has to believe in himself and keep his spirit alive. The famous dance performance is amazing, he has really sang that song for the movie.It was the last silent movie of chaplin. The scene shows his acceptence to move into the talkie era from the silent film era. The movie is till in 35th rank in imdb and has a hundred percent rating in rotten tomatoes and still stands as a greatest film ever. Solution Modern Times is one of the greatest movies in the history of film. The protogonist clearly depictts the poverty,struggle after the great depression times and how industrial age destroy the lives of the small employees. The assembly line of henry ford may have increased productivity but the employees are merged with the machinery as if they are blind machines.Every where chaplin go, the situation would be that he has to battle with the crowds for his livelihood or self respect. He clearly portrays the pain of being a small cog in the company which exploits its employees.He shows how america\'s race for automation have made life horrible for the employees when the company thinks that allowing employees a lunch break is wasting time. After getting cure from his nervous break down when he attempts to lift a fallen red fl.

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Include time header file #include Write main method like this : int main(){ time_t start_t, end_t; double diff_t; time(&start_t); // capturing start time int n; printf(\"Enter number of stuents (<=30): \"); scanf(\"%d\", &n); GradeBook *students = (GradeBook *)malloc(sizeof(GradeBook)*n); int i,j; // taking n entries for(i=0; i Solution Include time header file #include Write main method like this : int main(){ time_t start_t, end_t; double diff_t; time(&start_t); // capturing start time int n; printf(\"Enter number of stuents (<=30): \"); scanf(\"%d\", &n); GradeBook *students = (GradeBook *)malloc(sizeof(GradeBook)*n); int i,j; // taking n entries for(i=0; i.

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The short answer is no. The reason why you cant predict acid/base properties based on O/H is because many very strong acids and bases dont contain O or H. That being said the bronsted-lowry definition of acid and bases says that an acid is a substance that donates protons and a base is a substance that donates electron. According to that definition there is a very very weak correlation between having Hs to donate as protons and acid strength and conversely having Os and being a base (O- ions are a good proton acceptors because they are highly electronegative). Acids and bases are really better described by their electron donating and accepting capabilities of the compound as described by the lewis acid/base theory. An acid is really a compound that accepts electrons and a base is a compound which donates electrons. An H+ ion then is a compound which readily accepts electrons while O- ions readily donate electrons. However the H+ and O- ability to donate and accept electrons depends on many complicated factors of the compound as a whole and even its surrounding environment than just its quantity of Hs and Os. Try using wikipedia to gain a basic understanding of lewis acids. Solution The short answer is no. The reason why you cant predict acid/base properties based on O/H is because many very strong acids and bases dont contain O or H. That being said the bronsted-lowry definition of acid and bases says that an acid is a substance that donates protons and a base is a substance that donates electron. According to that definition there is a very very weak correlation between having Hs to donate as protons and acid strength and conversely having Os and being a base (O- ions are a good proton acceptors because they are highly electronegative). Acids and bases are really better described by their electron donating and accepting capabilities of the compound as described by the lewis acid/base theory. An acid is really a compound that accepts electrons and a base is a compound which donates electrons. An H+ ion then is a compound which readily accepts electrons while O- ions readily donate electrons. However the H+ and O- ability to donate and accept electrons depends on many complicated factors of the compound as a whole and even its surrounding environment than just its quantity of Hs and Os. Try using wikipedia to gain a basic understanding of lewis acids..

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First, let\'s start with naming binary ionic compounds. A binary ionic compound has one metal and one nonmetal present in the compound. Let\'s consider my username (rubidium.chloride) as an example. Rubidium chloride, or RbCl, is a binary ionic compound. The metal here is Rb (rubidium, group 1A) and the nonmetal is Cl (chlorine, group 7A). When you name binary ionic compounds, you mention the cation (positively charged ion) first (usually metals, those elements that appear on the left side of the periodic table have the tendency to form positively-charged ions). Then mention the anion (negatively charged ion). The cation is rubidium (Rb). We mention it thus: Rubidium The anion is chlorine. When we write the name of the anion [alongside with the cation], we drop the ending -ine (or whatever ending it may have) and replace it with -ide. So chlorine now becomes chlor + ide = chloride. Therefore, the name of the compound is Rubidium Chloride. When you write the formulas of binary ionic compounds, you use the criss-cross method. Here\'s how it works: Rubidium has a charge of +1. Chlorine has a charge of -1. You interchange the charges of both ions. These charges, when interchanged, become the subscripts of the elements in the compound. Hence, the compound now looks Rb1Cl1. Since the subscripts are all 1, we can remove them and write the formula as RbCl. Here\'s another example: Give the formula of the compound magnesium chloride. Mg has a charge of +2. Chlorine has a charge of -1. When you interchange the respective charges of magnesium and chlorine, we get the following formula: Mg1Cl2 We simplify this as MgCl2. A list of the common cations and ions is found at the back page or on the chapter of naming chemical compounds of your chemistry book. Take time to know them by heart. But what if... you\'ve got a compound named sodium nitrate. Ok. The formula is NaNO3. How did I know? Sodium nitrate is an example of a ternary ionic compound. A ternary ionic compound has two or more elements present in it. In this case, there are 3 (Na, N and O). The naming system of ternary ionic compounds is the same as that of binary ionic compounds. Let\'s name the participating ions: Na+ NO3- NO3- is the formula for the polyatomic ion (two or more elements joined together sharing a common charge; they act as one unit when they combine with other elements) nitrate. We interchange the charges of sodium and nitrate. Interchanging them gives us the formula NaNO3 To name this formula, just combine the name of the cation and anion together. In this case, it is sodium nitrate. What if we have a formula like this? Ba(OH)2 Don\'t worry. This is just barium hydroxide. Let\'s analyze why this came about. The charge of Ba is +2 and hydroxide (OH-) is -1. When you combine them together by interchanging subscripts, we get the following: BaOH2 Wait. The formula doesn\'t make sense. H is not the only atom having two of its kind, but O too. So we put parentheses around hydroxide to i.

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