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EBOLA VIRUS
PRESENTED BY:-
UDIT KR DIXIT
KHARAGPUR
1
OBJECTIVES
At the end of this topic you will be able to know
about :-
What is EBOLA?
 Mode of transmission of EVD.
 Signs & Symptoms of EVD.
 Diagnosis of EVD.
 Treatment/vaccine of EVD.
 How to prevent, Do's & Don't of EVD
2
EBOLA VIRUS
 Ebola is a deadly disease caused by a virus.
 After entering the body, it kills cells, making some of
them explode.
 It wrecks the immune system, causes heavy bleeding
inside the body, and damages almost every organ.
 Ebola virus disease(EVD),also known as Ebola
haemorrhagic fever (EHF).
3
FIRST APPEARANCE OF EVD
 The disease was first identify in 1976 in two
simultaneous outbreaks,
1) Nazra( a town in South Sudan)
2)Yambuku( Democratic Republic of the
Congo)
a village near the Ebola river.
 From which disease takes is name EBOLA.
4
RECENTLY AFFECTED COUNTRIES
 Nigeria
Senegal
Liberia
Guinea
Sierra Leone
Spain
USA 5
6
Modes of Transmission
 People can get Ebola in West Africa by preparing these sick
animals for food.
 The virus spreads by direct contact with body fluids, such
as blood, of an infected human or other animals.
 Health-care workers have frequently been infected while
treating patients with suspected or confirmed EVD,due to
close contact with patients.
7
Modes of Transmission
 Natural reservoir host of Ebola virus has not yet been
identified.
 Researchers believed that the first patient becomes
infected through contact with an infected animals like
chimpanzees, gorillas, fruit bats, monkeys etc.
8
 BODY FLUIDS
EBOLA VIRUS
Blood
Saliva Sweat
Types of Body Fluids That
involves in transmission of Ebola virus
9
NEEDLES
SYRINGES
EBOLA
VIRUS
CONTAMINATED OBJECTS THROUGH
WHICH EBOLA VIRUS TRANSMITS
10
• TOUCHING THE SOILED CLOTHES OF INFECTED
PERSON
• HAVING SEXUAL CONTACT WITH INFECTED PERSON
• HANDLING UNSTERILISED MEDICAL EQUIPMENT
OTHER WAYES IN WHICH EBOLA VIRUS
CAN TRANSMIT
11
Signs & Symptoms
 Incubation Period: 2 to 21 days
 Fever, headaches, joint and muscle aches, sore throat,
and weakness.
 These are followed by diarrhea, vomiting, & stomach
pains.
 Initial symptoms include high fever (at least 102°F). 12
Signs & Symptoms
 In some cases, internal and external bleeding may
occur. This begins 5 to 7 days after first symptoms.
 Death, if it occurs follows 06 to 16 days from 1st
symptoms & is often due to low blood pressure from
fluid loss.
 People are often in coma near the end of life.
13
FEVER HEADACHE
14
NAUSEA TIREDNESS
15
Diarrhea Vomiting
16
Rashes
BRAIN DAMAGE
17
18
DIAGNOSIS OF EVD
 Ebola is often confused with Malaria, Typhoid
fever, dysentery, etc.
 So Ebola is diagnosed through saliva and urine
tests.
 Blood samples are tested for viral RNA, viral
antibodies or for the virus itself to confirm the
diagnosis. 19
DIAGNOSIS OF EVD
 Detecting the viral RNA by polymerase chain
reaction (PCR).
 Detecting proteins by Enzyme-linked Immuno
Sorbent Assay (ELISA).
 These are methods best used in the early stages
of the disease and also for detecting the virus in
human remains. 20
Treatment/Vaccine Of EVD
 Treatment effective begun within 04 days and continued
for 10 days course.
There is no standard treatment & Vaccine for Ebola.
Only supportive treatment, which includes balancing
patient's fluids ,maintaining oxygen, blood pressure, &
treating any complications. 21
 Researchers have recently developed a new drug target in
the Ebola virus that could be used against it .
 University of Utah chemists have produced a molecule
known as peptide mimic that displays a functionally
critical region of the virus that is universally conserved in
all known species of Ebola
A New Drug Target For Ebola Virus
22
 If have sudden fever, diarrhoea, or vomiting, go to the nearest
health facility
 Make no contact with Ebola affected people
 Use a special kind of clothes while treating Ebola affected
people
HOW TO PREVENT EVD
23
24
REVIEW
 At the end of this topic you are now able to know
about.
What is EBOLA?
 Mode of transmission of EVD
 Sings & Symptoms of EVD
 Diagnosis of EVD
 Treatment/vaccine of EVD
 How to prevent, Do's & Don't of EVD. 25
CONCLUSION
In a nutshell we can say that
26
27
EVALUATION
Q.EHF STANDS FOR ?
A.EBOLA HAEMORRAGIC FEVER.
28
29

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Ebola virus

  • 1. EBOLA VIRUS PRESENTED BY:- UDIT KR DIXIT KHARAGPUR 1
  • 2. OBJECTIVES At the end of this topic you will be able to know about :- What is EBOLA?  Mode of transmission of EVD.  Signs & Symptoms of EVD.  Diagnosis of EVD.  Treatment/vaccine of EVD.  How to prevent, Do's & Don't of EVD 2
  • 3. EBOLA VIRUS  Ebola is a deadly disease caused by a virus.  After entering the body, it kills cells, making some of them explode.  It wrecks the immune system, causes heavy bleeding inside the body, and damages almost every organ.  Ebola virus disease(EVD),also known as Ebola haemorrhagic fever (EHF). 3
  • 4. FIRST APPEARANCE OF EVD  The disease was first identify in 1976 in two simultaneous outbreaks, 1) Nazra( a town in South Sudan) 2)Yambuku( Democratic Republic of the Congo) a village near the Ebola river.  From which disease takes is name EBOLA. 4
  • 5. RECENTLY AFFECTED COUNTRIES  Nigeria Senegal Liberia Guinea Sierra Leone Spain USA 5
  • 6. 6
  • 7. Modes of Transmission  People can get Ebola in West Africa by preparing these sick animals for food.  The virus spreads by direct contact with body fluids, such as blood, of an infected human or other animals.  Health-care workers have frequently been infected while treating patients with suspected or confirmed EVD,due to close contact with patients. 7
  • 8. Modes of Transmission  Natural reservoir host of Ebola virus has not yet been identified.  Researchers believed that the first patient becomes infected through contact with an infected animals like chimpanzees, gorillas, fruit bats, monkeys etc. 8
  • 9.  BODY FLUIDS EBOLA VIRUS Blood Saliva Sweat Types of Body Fluids That involves in transmission of Ebola virus 9
  • 11. • TOUCHING THE SOILED CLOTHES OF INFECTED PERSON • HAVING SEXUAL CONTACT WITH INFECTED PERSON • HANDLING UNSTERILISED MEDICAL EQUIPMENT OTHER WAYES IN WHICH EBOLA VIRUS CAN TRANSMIT 11
  • 12. Signs & Symptoms  Incubation Period: 2 to 21 days  Fever, headaches, joint and muscle aches, sore throat, and weakness.  These are followed by diarrhea, vomiting, & stomach pains.  Initial symptoms include high fever (at least 102°F). 12
  • 13. Signs & Symptoms  In some cases, internal and external bleeding may occur. This begins 5 to 7 days after first symptoms.  Death, if it occurs follows 06 to 16 days from 1st symptoms & is often due to low blood pressure from fluid loss.  People are often in coma near the end of life. 13
  • 18. 18
  • 19. DIAGNOSIS OF EVD  Ebola is often confused with Malaria, Typhoid fever, dysentery, etc.  So Ebola is diagnosed through saliva and urine tests.  Blood samples are tested for viral RNA, viral antibodies or for the virus itself to confirm the diagnosis. 19
  • 20. DIAGNOSIS OF EVD  Detecting the viral RNA by polymerase chain reaction (PCR).  Detecting proteins by Enzyme-linked Immuno Sorbent Assay (ELISA).  These are methods best used in the early stages of the disease and also for detecting the virus in human remains. 20
  • 21. Treatment/Vaccine Of EVD  Treatment effective begun within 04 days and continued for 10 days course. There is no standard treatment & Vaccine for Ebola. Only supportive treatment, which includes balancing patient's fluids ,maintaining oxygen, blood pressure, & treating any complications. 21
  • 22.  Researchers have recently developed a new drug target in the Ebola virus that could be used against it .  University of Utah chemists have produced a molecule known as peptide mimic that displays a functionally critical region of the virus that is universally conserved in all known species of Ebola A New Drug Target For Ebola Virus 22
  • 23.  If have sudden fever, diarrhoea, or vomiting, go to the nearest health facility  Make no contact with Ebola affected people  Use a special kind of clothes while treating Ebola affected people HOW TO PREVENT EVD 23
  • 24. 24
  • 25. REVIEW  At the end of this topic you are now able to know about. What is EBOLA?  Mode of transmission of EVD  Sings & Symptoms of EVD  Diagnosis of EVD  Treatment/vaccine of EVD  How to prevent, Do's & Don't of EVD. 25
  • 26. CONCLUSION In a nutshell we can say that 26
  • 27. 27
  • 28. EVALUATION Q.EHF STANDS FOR ? A.EBOLA HAEMORRAGIC FEVER. 28
  • 29. 29