Copyright - Jackie Oldham, Manchester Integrated Medicine and Innovative Technologies, University of Manchester, 2011

1. MIMIT innovation model: A journey from patient needs to (commercial) healthcare solutions. Jackie Oldham Director MIMIT Dr Roz Kelly and Dr Sian Taylor

2. MANCHESTER - INTEGRATING MEDICINE & INNOVATIVE TECHNOLOGY www.mimit.org.uk 1 st International Affiliate of

3. 1998 CIMIT: A formal consortium among 13 Boston institutions, International Affiliates, and in collaboration with TATRC/DoD In Collaboration with and support from the Telemedicine and Advanced Technology Research Center 1999 2000 2001 2002 2003 2004 2005 2006 2007 2008 A Center at VA Boston 2009 2010 International Affiliates

5. Established 1824 One of the country’s major research universities Annual income of £788million 40,000 students By 2015 £650million capital investment Most prolific in the UK for IP and invention disclosures

6. Established 2001 (amalgamation of six Trusts) Largest University NHS Teaching Trust in the UK 1,245 beds, 8,000 staff Annual turnover £483million

7. Major acute teaching Trust 4,300 staff 855 beds Annual turnover £211million Northwest Lung Research Unit (led by Ashley Woodcock) Shortlisted for NHS Hospital of the Year 2011

8. Largest cancer centre in Europe More than 40,000 patients per year 2,500 staff £173million annual turnover

9. 850 in patient beds 5,080 staff 400,000 patient per year 328million annual turnover One of the best hospitals in the NHS

10. NHS Greater Manchester Cluster Statutory functions of each of ten PCTs across greater Manchester

12. MIMIT TM - Innovation Development Pathway Project Proposals Industry Engagement MIMIT Funding Site Miner dialogue with clinical community Clinical Unmet Need ILP targeted scoping or other introduction Dissemination of need To the widest group of scientists, engineers and designers. Validation of need Project award Optional Industry Funding or involvement Best Ideas Patients and Carers Six month review Facilitated Grant Funding Other Unmet Need Market Analysis Integration of need and solution Project Delivery License/spin out/other Operational/ Management team Forum

18. Christie Cancer urology, pathology medical physics, University of Manchester Chem eng, Tissue eng, Biomaterials, Polymer chem, Photon sciences, Biomed eng, Electrical & electronic eng, Manchester informatics, Mechanical and aerospace eng, Pharmaceutical sciences, Material sciences CMFT Rehab, renal medicine ENT/ head and neck surgery, maternal & foetal health, ophthalmic surgery, radiology, cardiovascular, nephrology, paediatric neurology Salford Rheumatology, diabetes, Dermatology, GI neurosciences, Salford PCT Vascular South Plastic surgery, vascular surgery, transfusion services, respiratory

19. Science Bridge Connections University of Manchester South Man CMFT Adults CMFT Children’s Tissue Engineering Chemical Eng & cardiovascular Med Pharmacy / biomaterials Mathematics Christie Wolfson Molecular Imaging/ neurology Rehab Science Plastic surgery Respiratory medicine Biomedical imaging ENT Anaesthetics Paediatric oncology Paediatric ICU Neurology Neonatology Terenghi Yuan El-deredy Parker Lionheart McCann Oldham McGrouther Woodcock Fowler Herholz Homer Coleman Makin Playfor Martland Tirelli Psychological Sciences Electrical Eng. Victor MIT Harvard Medical School Draper Lab Boston University Brigham Women’s Massachusetts General Boston Children’s Tissue Engineering Guttag Biomed Engineering Radiology Neurology Biomedical Engineering Rehabilitation Services Pathology & Health Sciences Laryngeal Surgery and Voice Rehab Anaesthetics Paediatric ICU Grinstaff Kikinis Schacter Trevejo Borenstein Zaman Stevenson Schoen Hillman Goldman Wolf Gaydecki Salford Royal Adult ICU Dark

20. Examples of projects

21. Cumulative disclosures 61 considered, 22 funded, 12 under consideration)

32. MIMIT TM is supported by: Manchester Academic Health Science Centre (MAHSC)