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Afternoon conference
Ext ปุณณะปารย์ ธีระทีปต์ธรณ์ PCM
ผู้ป่วยชายไทยอายุ 44ปี
cc: ปวดสะโพกซ้ายมากขึ้น 2 mo
PTA
PI: 2 yr PTA ปวดขาหนีบข้างซ้ายขณะเดิน
1 yr PTA ปวดลึกๆบริเวณสะโพกซ้าย เดินลาบาก
ขึ้นเนื่องจากเจ็บสะโพกซ้าย
2 mo PTA ปวดสะโพกทั้ง2ข้าง (ซ้ายมากกว่า
ขวา) เดินไม่ได้เนื่องจากปวดมาก ต้องนั่งรถเข็น จึง
มารพ. ไม่มีไข้ ไม่ชา ไม่อ่อนแรง
PH: U/D gout รักษาที่รพ เทพารักษ์ รับประทานยา
สม่าเสมอ
ไม่เคยได้รับอุบัติเหตุ
สูบบุหรี่มา 30ปี 1/2pack/day
(15pack.year)
ดื่มเหล้าขาวมา 20ปี 1/2ขวด(~250ml)/day เลิก
มา3ปี
รับประทานยาสมุนไพร 6x2 o pc มา2ปี
Physical examination
Vital signs: BT 36.5 C PR 82 bpm BP 105/70mmHg RR 16/min
GA: A middle aged Thai male, good consciousness, well cooperated
HEENT: not pale conjunctivae, anicteric sclerae
Heart: normal s1s2, no murmur
Lungs: clear and equal breath sounds both lungs
Abdomen: soft, not tender
Neurological exam E4V5M6, pupils 3mm RTLBE
Orthopedic examination
Antalgic gait
Inspection no swelling, no ecchymosis
Full ROM both hips
Pain on passive and active motion
Anvil and rolling test - positive
Neurovascular intact
Physical examination
Diagnosis: Osteonecrosis of femoral head
both hips
(Ficat IV left hip, Ficat III right hip)
Management: Left Total hip arthroplasty
Osteonecrosis
of Femoral Head
Content
• Definition
• Anatomy
• Etiology
• Diagnosis
• Classification
• Management
Definition
• Osteonecrosis / Avascular necrosis
• Osteonecrosis = Dead bone
• Avascular = loss of circulation due to potential causes
Anatomy
femoral head is at risk because its blood supply is retrograde and tenuous
enclosed by cartilage, giving restricted access to local blood vessels
Etiology
10%
• Corticosteroid
• 2 gm/month of prednisolone at least 3 months
• Alcohol
• <400 ml per week increase 3X
• >400 ml per week increase 9.8X
• Smoking relative risk 3.9
• Chronic inflammatory disease - SLE, RA
Etiology
Clinical presentations
• Asymptomatic (early)
• Groin pain on ambulation or weight bearing followed by
hip, thigh and buttock pain
• Hip pain on extreme ROM particularly when internal rotate
• Bilateral 40-80%
Diagnosis
• Symptoms
• Plain radiology
• AP view, Frog-leg lateral view
• Crescent sign best seen in frog leg position
• MRI
Crescent sign
Double line sign
Ficat and Arlet Classification
Clinical Plain film MRI
Stage 0 No pain Normal Abnormal
Stage I Pain Normal +
Stage II +
Subchondral sclerosis and
cysts (IIA)
Crescent sign (IIB)
+
Stage III +
Cortical femoral head
collapsed
+
Stage IV +
Narrow joint space and
acetabulum
+
Ficat I
Ficat IIA
Ficat IIB
Ficat III
Ficat IV
Management
• Pre-subchondral collpase
• Subchondral collapse
• Prophylaxis treatment for contralateral side
Left untreated..
Rate of collapse >85% in 2 years
in symptomatic patients
Pre-subchondral collapse
Ficat 0-II
Non-operative treatment
• Restricted weight-bearing
• Pharmacological agents
• Pulsed electromagnetic field stimulation
• Extracoporeal shockwave therapy
• Hyperbaric oxygen therapy
Pharmacological agents
• Lipid lowering agents
• Anticoagulants
• Bisphosphonates
Operative treatment
Joint preserving procedure
• Core decompression
• Vascularized fibular
grafting
Prosthetic replacement
• Total hip arthroplasty
Core decompression
• Reduce intraosseus
pressure in the femoral
head
• Stimulate
neovascularization
• Only Pain relief,
NO advantage in prevention
of collapse
• Ficat and Arlet I, II
Vascularized fibular grafting
• Ficat stage II, III (10 year-
follow up)
• only 13 of 76 (17 percent)
were converted to THA
• Ficat arlet stage II, III
THA
• Intractable pain
• Acetabular involvement
Prophylaxis treatment for
contralateral side
• Plain film on contralateral side
• MRI if normal radiography
• Leision <30% conservative and follow up
• Leision >30% operative treatment
• Severe pain - core decompression
Collapse?
Precollapse Postcollapse
To relieve pain
To prevent collase
Symptomatic
Conservative
treatment
Core decompression
Vascularized bone
grafting
THA
Intractable pain
Acetabular invovementAsymptomatic
Vascularized bone
grafting
Yes No

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Onfh poon

  • 1. Afternoon conference Ext ปุณณะปารย์ ธีระทีปต์ธรณ์ PCM
  • 3. PI: 2 yr PTA ปวดขาหนีบข้างซ้ายขณะเดิน 1 yr PTA ปวดลึกๆบริเวณสะโพกซ้าย เดินลาบาก ขึ้นเนื่องจากเจ็บสะโพกซ้าย 2 mo PTA ปวดสะโพกทั้ง2ข้าง (ซ้ายมากกว่า ขวา) เดินไม่ได้เนื่องจากปวดมาก ต้องนั่งรถเข็น จึง มารพ. ไม่มีไข้ ไม่ชา ไม่อ่อนแรง
  • 4. PH: U/D gout รักษาที่รพ เทพารักษ์ รับประทานยา สม่าเสมอ ไม่เคยได้รับอุบัติเหตุ สูบบุหรี่มา 30ปี 1/2pack/day (15pack.year) ดื่มเหล้าขาวมา 20ปี 1/2ขวด(~250ml)/day เลิก มา3ปี รับประทานยาสมุนไพร 6x2 o pc มา2ปี
  • 5. Physical examination Vital signs: BT 36.5 C PR 82 bpm BP 105/70mmHg RR 16/min GA: A middle aged Thai male, good consciousness, well cooperated HEENT: not pale conjunctivae, anicteric sclerae Heart: normal s1s2, no murmur Lungs: clear and equal breath sounds both lungs Abdomen: soft, not tender Neurological exam E4V5M6, pupils 3mm RTLBE
  • 6. Orthopedic examination Antalgic gait Inspection no swelling, no ecchymosis Full ROM both hips Pain on passive and active motion Anvil and rolling test - positive Neurovascular intact Physical examination
  • 7.
  • 8.
  • 9. Diagnosis: Osteonecrosis of femoral head both hips (Ficat IV left hip, Ficat III right hip) Management: Left Total hip arthroplasty
  • 10.
  • 12. Content • Definition • Anatomy • Etiology • Diagnosis • Classification • Management
  • 13. Definition • Osteonecrosis / Avascular necrosis • Osteonecrosis = Dead bone • Avascular = loss of circulation due to potential causes
  • 14. Anatomy femoral head is at risk because its blood supply is retrograde and tenuous enclosed by cartilage, giving restricted access to local blood vessels
  • 16. • Corticosteroid • 2 gm/month of prednisolone at least 3 months • Alcohol • <400 ml per week increase 3X • >400 ml per week increase 9.8X • Smoking relative risk 3.9 • Chronic inflammatory disease - SLE, RA Etiology
  • 17. Clinical presentations • Asymptomatic (early) • Groin pain on ambulation or weight bearing followed by hip, thigh and buttock pain • Hip pain on extreme ROM particularly when internal rotate • Bilateral 40-80%
  • 18. Diagnosis • Symptoms • Plain radiology • AP view, Frog-leg lateral view • Crescent sign best seen in frog leg position • MRI
  • 19.
  • 22. Ficat and Arlet Classification Clinical Plain film MRI Stage 0 No pain Normal Abnormal Stage I Pain Normal + Stage II + Subchondral sclerosis and cysts (IIA) Crescent sign (IIB) + Stage III + Cortical femoral head collapsed + Stage IV + Narrow joint space and acetabulum +
  • 28. Management • Pre-subchondral collpase • Subchondral collapse • Prophylaxis treatment for contralateral side Left untreated.. Rate of collapse >85% in 2 years in symptomatic patients
  • 29. Pre-subchondral collapse Ficat 0-II Non-operative treatment • Restricted weight-bearing • Pharmacological agents • Pulsed electromagnetic field stimulation • Extracoporeal shockwave therapy • Hyperbaric oxygen therapy
  • 30. Pharmacological agents • Lipid lowering agents • Anticoagulants • Bisphosphonates
  • 31. Operative treatment Joint preserving procedure • Core decompression • Vascularized fibular grafting Prosthetic replacement • Total hip arthroplasty
  • 32. Core decompression • Reduce intraosseus pressure in the femoral head • Stimulate neovascularization • Only Pain relief, NO advantage in prevention of collapse • Ficat and Arlet I, II
  • 33. Vascularized fibular grafting • Ficat stage II, III (10 year- follow up) • only 13 of 76 (17 percent) were converted to THA • Ficat arlet stage II, III
  • 34. THA • Intractable pain • Acetabular involvement
  • 35. Prophylaxis treatment for contralateral side • Plain film on contralateral side • MRI if normal radiography • Leision <30% conservative and follow up • Leision >30% operative treatment • Severe pain - core decompression
  • 36. Collapse? Precollapse Postcollapse To relieve pain To prevent collase Symptomatic Conservative treatment Core decompression Vascularized bone grafting THA Intractable pain Acetabular invovementAsymptomatic Vascularized bone grafting Yes No

Editor's Notes

  1. ข้างขวา collapse ของ femoral head Subchondral Radiolucent line No Joint space narrowing ข้างซ้าย Joint space narrowing ลักษณธะของ 2 OA Scleroric change
  2. MRI sens >95%
  3. Subchondral radiolucency บ่งบอกว่ามี subchondral collapse