The document outlines the schedule for a toxicology conference taking place on June 11-12, 2018. It includes the following:
- An opening ceremony and plenary talks on June 11 from 9:30-11:20 on topics like synthetic pyrethroids and puffer fish poisoning.
- Three sessions on June 11 from 11:20-13:30, 14:00-16:00, and 16:15-18:15 covering a range of topics in occupational, in vitro/in vivo, and pharmaceutical toxicology.
- Additional sessions and talks on June 12 from 10:00-16:00 covering medical, clinical, and food toxicology topics as well as metallic and regulatory toxicology.
We are glad to announce that scientific program for the 2019 Edition of World Pediatrics Conference (2019WPC) has been released which is going to take place in Ramada by Wyndham Singapore at Zhongshan Park, Singapore from September 10-11, 2019.
We welcome you for the scientific collaboration with the 2019WPC in Singapore. Website: https://pediatrics.episirus.org/
AAPS Rocky Mountain Discussion Group (RMDG) Annual Meeting Schedule - "Expanding the Frontiers of Pharmaceutical Sciences" Seattle, WA. June 12 - June 13
After the success of Clinical Microbiology 2012, Clinical Microbiology 2013 and with the tremendous response of Clinical Microbiology 2014 and Clinical Microbiology 2015 ,OMICS Group International is glad to announce 6th International conference on Clinical Microbiology & Microbial Genomics (Clinical Microbiology-2016) during October 24-26, 2016 at Rome, Italy.
PAMAM/5-fluorouracil drug conjugate for targeting E6 and E7 oncoproteins in c...Arun kumar
In the present study, poly(amidoamine)/5-fluorouracil (PAMAM/5-FU) was prepared and used as
a conjugate system for delivering drugs to target E6 and E7 oncoproteins, which are predominant in
cervical cancers. Specifically, molecular docking analysis was used to investigate the interaction
between the PAMAM/5-FU and E6/E7 oncoproteins, which showed that the PAMAM/5-FU conjugate
had a higher affinity for the oncoprotein than for 5-FU. Different generations of PAMAM dendrimers
(0.5G, 1.0G, 1.5G, 2.0G, and 2.5G) were synthesized, characterized and tested as drug carriers for 5-
FU. The PAMAM and PAMAM/5-FU drug conjugate showed less toxicity over COS-7 and HeLa cell
lines. Laser confocal imaging and western blotting for tumor suppressor proteins pRb and p53 were
used to confirm the interaction of PAMAM/5-FU with E6/E7 oncoproteins. Hematological analysis of
PAMAM/5-FU using BALB/c female mice with cervical cancer confirmed the less toxic nature of this
material. Based on these results, the developed PAMAM/5-FU conjugate is a potential candidate for
the treatment of cervical cancer.
We are glad to announce that scientific program for the 2019 Edition of World Pediatrics Conference (2019WPC) has been released which is going to take place in Ramada by Wyndham Singapore at Zhongshan Park, Singapore from September 10-11, 2019.
We welcome you for the scientific collaboration with the 2019WPC in Singapore. Website: https://pediatrics.episirus.org/
AAPS Rocky Mountain Discussion Group (RMDG) Annual Meeting Schedule - "Expanding the Frontiers of Pharmaceutical Sciences" Seattle, WA. June 12 - June 13
After the success of Clinical Microbiology 2012, Clinical Microbiology 2013 and with the tremendous response of Clinical Microbiology 2014 and Clinical Microbiology 2015 ,OMICS Group International is glad to announce 6th International conference on Clinical Microbiology & Microbial Genomics (Clinical Microbiology-2016) during October 24-26, 2016 at Rome, Italy.
PAMAM/5-fluorouracil drug conjugate for targeting E6 and E7 oncoproteins in c...Arun kumar
In the present study, poly(amidoamine)/5-fluorouracil (PAMAM/5-FU) was prepared and used as
a conjugate system for delivering drugs to target E6 and E7 oncoproteins, which are predominant in
cervical cancers. Specifically, molecular docking analysis was used to investigate the interaction
between the PAMAM/5-FU and E6/E7 oncoproteins, which showed that the PAMAM/5-FU conjugate
had a higher affinity for the oncoprotein than for 5-FU. Different generations of PAMAM dendrimers
(0.5G, 1.0G, 1.5G, 2.0G, and 2.5G) were synthesized, characterized and tested as drug carriers for 5-
FU. The PAMAM and PAMAM/5-FU drug conjugate showed less toxicity over COS-7 and HeLa cell
lines. Laser confocal imaging and western blotting for tumor suppressor proteins pRb and p53 were
used to confirm the interaction of PAMAM/5-FU with E6/E7 oncoproteins. Hematological analysis of
PAMAM/5-FU using BALB/c female mice with cervical cancer confirmed the less toxic nature of this
material. Based on these results, the developed PAMAM/5-FU conjugate is a potential candidate for
the treatment of cervical cancer.
Recomendações da OMS sobre cuidados maternos e neonatais para uma experiência pós-natal positiva.
Em consonância com os ODS – Objetivos do Desenvolvimento Sustentável e a Estratégia Global para a Saúde das Mulheres, Crianças e Adolescentes, e aplicando uma abordagem baseada nos direitos humanos, os esforços de cuidados pós-natais devem expandir-se para além da cobertura e da simples sobrevivência, de modo a incluir cuidados de qualidade.
Estas diretrizes visam melhorar a qualidade dos cuidados pós-natais essenciais e de rotina prestados às mulheres e aos recém-nascidos, com o objetivo final de melhorar a saúde e o bem-estar materno e neonatal.
Uma “experiência pós-natal positiva” é um resultado importante para todas as mulheres que dão à luz e para os seus recém-nascidos, estabelecendo as bases para a melhoria da saúde e do bem-estar a curto e longo prazo. Uma experiência pós-natal positiva é definida como aquela em que as mulheres, pessoas que gestam, os recém-nascidos, os casais, os pais, os cuidadores e as famílias recebem informação consistente, garantia e apoio de profissionais de saúde motivados; e onde um sistema de saúde flexível e com recursos reconheça as necessidades das mulheres e dos bebês e respeite o seu contexto cultural.
Estas diretrizes consolidadas apresentam algumas recomendações novas e já bem fundamentadas sobre cuidados pós-natais de rotina para mulheres e neonatos que recebem cuidados no pós-parto em unidades de saúde ou na comunidade, independentemente dos recursos disponíveis.
É fornecido um conjunto abrangente de recomendações para cuidados durante o período puerperal, com ênfase nos cuidados essenciais que todas as mulheres e recém-nascidos devem receber, e com a devida atenção à qualidade dos cuidados; isto é, a entrega e a experiência do cuidado recebido. Estas diretrizes atualizam e ampliam as recomendações da OMS de 2014 sobre cuidados pós-natais da mãe e do recém-nascido e complementam as atuais diretrizes da OMS sobre a gestão de complicações pós-natais.
O estabelecimento da amamentação e o manejo das principais intercorrências é contemplada.
Recomendamos muito.
Vamos discutir essas recomendações no nosso curso de pós-graduação em Aleitamento no Instituto Ciclos.
Esta publicação só está disponível em inglês até o momento.
Prof. Marcus Renato de Carvalho
www.agostodourado.com
ARTIFICIAL INTELLIGENCE IN HEALTHCARE.pdfAnujkumaranit
Artificial intelligence (AI) refers to the simulation of human intelligence processes by machines, especially computer systems. It encompasses tasks such as learning, reasoning, problem-solving, perception, and language understanding. AI technologies are revolutionizing various fields, from healthcare to finance, by enabling machines to perform tasks that typically require human intelligence.
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Basavarajeeyam is a Sreshta Sangraha grantha (Compiled book ), written by Neelkanta kotturu Basavaraja Virachita. It contains 25 Prakaranas, First 24 Chapters related to Rogas& 25th to Rasadravyas.
Basavarajeeyam is an important text for ayurvedic physician belonging to andhra pradehs. It is a popular compendium in various parts of our country as well as in andhra pradesh. The content of the text was presented in sanskrit and telugu language (Bilingual). One of the most famous book in ayurvedic pharmaceutics and therapeutics. This book contains 25 chapters called as prakaranas. Many rasaoushadis were explained, pioneer of dhatu druti, nadi pareeksha, mutra pareeksha etc. Belongs to the period of 15-16 century. New diseases like upadamsha, phiranga rogas are explained.
Flu Vaccine Alert in Bangalore Karnatakaaddon Scans
As flu season approaches, health officials in Bangalore, Karnataka, are urging residents to get their flu vaccinations. The seasonal flu, while common, can lead to severe health complications, particularly for vulnerable populations such as young children, the elderly, and those with underlying health conditions.
Dr. Vidisha Kumari, a leading epidemiologist in Bangalore, emphasizes the importance of getting vaccinated. "The flu vaccine is our best defense against the influenza virus. It not only protects individuals but also helps prevent the spread of the virus in our communities," he says.
This year, the flu season is expected to coincide with a potential increase in other respiratory illnesses. The Karnataka Health Department has launched an awareness campaign highlighting the significance of flu vaccinations. They have set up multiple vaccination centers across Bangalore, making it convenient for residents to receive their shots.
To encourage widespread vaccination, the government is also collaborating with local schools, workplaces, and community centers to facilitate vaccination drives. Special attention is being given to ensuring that the vaccine is accessible to all, including marginalized communities who may have limited access to healthcare.
Residents are reminded that the flu vaccine is safe and effective. Common side effects are mild and may include soreness at the injection site, mild fever, or muscle aches. These side effects are generally short-lived and far less severe than the flu itself.
Healthcare providers are also stressing the importance of continuing COVID-19 precautions. Wearing masks, practicing good hand hygiene, and maintaining social distancing are still crucial, especially in crowded places.
Protect yourself and your loved ones by getting vaccinated. Together, we can help keep Bangalore healthy and safe this flu season. For more information on vaccination centers and schedules, residents can visit the Karnataka Health Department’s official website or follow their social media pages.
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These simplified slides by Dr. Sidra Arshad present an overview of the non-respiratory functions of the respiratory tract.
Learning objectives:
1. Enlist the non-respiratory functions of the respiratory tract
2. Briefly explain how these functions are carried out
3. Discuss the significance of dead space
4. Differentiate between minute ventilation and alveolar ventilation
5. Describe the cough and sneeze reflexes
Study Resources:
1. Chapter 39, Guyton and Hall Textbook of Medical Physiology, 14th edition
2. Chapter 34, Ganong’s Review of Medical Physiology, 26th edition
3. Chapter 17, Human Physiology by Lauralee Sherwood, 9th edition
4. Non-respiratory functions of the lungs https://academic.oup.com/bjaed/article/13/3/98/278874
Explore natural remedies for syphilis treatment in Singapore. Discover alternative therapies, herbal remedies, and lifestyle changes that may complement conventional treatments. Learn about holistic approaches to managing syphilis symptoms and supporting overall health.
Ozempic: Preoperative Management of Patients on GLP-1 Receptor Agonists Saeid Safari
Preoperative Management of Patients on GLP-1 Receptor Agonists like Ozempic and Semiglutide
ASA GUIDELINE
NYSORA Guideline
2 Case Reports of Gastric Ultrasound
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...Oleg Kshivets
RESULTS: Overall life span (LS) was 2252.1±1742.5 days and cumulative 5-year survival (5YS) reached 73.2%, 10 years – 64.8%, 20 years – 42.5%. 513 LCP lived more than 5 years (LS=3124.6±1525.6 days), 148 LCP – more than 10 years (LS=5054.4±1504.1 days).199 LCP died because of LC (LS=562.7±374.5 days). 5YS of LCP after bi/lobectomies was significantly superior in comparison with LCP after pneumonectomies (78.1% vs.63.7%, P=0.00001 by log-rank test). AT significantly improved 5YS (66.3% vs. 34.8%) (P=0.00000 by log-rank test) only for LCP with N1-2. Cox modeling displayed that 5YS of LCP significantly depended on: phase transition (PT) early-invasive LC in terms of synergetics, PT N0—N12, cell ratio factors (ratio between cancer cells- CC and blood cells subpopulations), G1-3, histology, glucose, AT, blood cell circuit, prothrombin index, heparin tolerance, recalcification time (P=0.000-0.038). Neural networks, genetic algorithm selection and bootstrap simulation revealed relationships between 5YS and PT early-invasive LC (rank=1), PT N0—N12 (rank=2), thrombocytes/CC (3), erythrocytes/CC (4), eosinophils/CC (5), healthy cells/CC (6), lymphocytes/CC (7), segmented neutrophils/CC (8), stick neutrophils/CC (9), monocytes/CC (10); leucocytes/CC (11). Correct prediction of 5YS was 100% by neural networks computing (area under ROC curve=1.0; error=0.0).
CONCLUSIONS: 5YS of LCP after radical procedures significantly depended on: 1) PT early-invasive cancer; 2) PT N0--N12; 3) cell ratio factors; 4) blood cell circuit; 5) biochemical factors; 6) hemostasis system; 7) AT; 8) LC characteristics; 9) LC cell dynamics; 10) surgery type: lobectomy/pneumonectomy; 11) anthropometric data. Optimal diagnosis and treatment strategies for LC are: 1) screening and early detection of LC; 2) availability of experienced thoracic surgeons because of complexity of radical procedures; 3) aggressive en block surgery and adequate lymph node dissection for completeness; 4) precise prediction; 5) adjuvant chemoimmunoradiotherapy for LCP with unfavorable prognosis.
Lung Cancer: Artificial Intelligence, Synergetics, Complex System Analysis, S...
World summint on toxicology 2018 program rome luisetto m
1. 08:30-09:30
09:30-09:35 Introduction
09:35-10:00 Opening Ceremony
Plenary Talk on
10:00-10:40 Title: Cypermethrin as Synthetic Pyrethroid and Environmental Threatening
Zeliha Selamoglu, Omer Halisdemir University, Turkey
Keynote Session
10:40-11:10 Title: A fishy Tale- Puffer fish poisoning in Bangladesh
Mohammad Robed Amin, Dhaka Medical College, Bangladesh
11:10-11:20 COFFEE BREAK
11:20-11:50
Title:Environmental Risk Assessment of Heavy Metal in Surface Dust
Caused by E-waste Recycling Activities
Anamika Tripathi, Hindu College,India
Title: Heavy Metals Toxicity and the Environment – Indian Context
Ch. Sanjay,Gitam University, India
Workshop on
12:20-13:20 Title:Toxicity of cigarette smoking compounds for cardiovascular system: A fact or
belief?
Aurelio Leone, Independent researcher, Italy
13:20-13:30 Group Photo
13:30-:14:00 Lunch Break
Session 1 Occupational and Environmental Toxicology
Session Chair Zeliha Selamoglu
Session Co-chair Yet to be finalized
Title: Comparative Health Effects of Carbon Nanotubes and Elongated Mineral
Fibers:What We Know and Don’t Know
Anna A. Shvedova. NIOSH,United States
Title: Hemotopoietic toxicity and blood diseases induced by benzene exposure
Cheng Peng, Queensland Alliance for Environmental Health Sciences, Australia
Day 1 June 11,2018
MainHall
Chair Person of Toxicology-2018, Aurelio Leone, Independent researcher, Italy
Co-Chair of Toxicology-2018, Antonio Rodríguez Valencia, National Autonomous University
11:50-12:20
14:00-14:20
14:20-14:40
2. Title: Base resolution DNA methylomes reveal vulnerable genomic loci due to
epigenetic perturbation from both Bisphenol A (BPA) and arsenic exposure
Zhibin Wang, Johns Hopkins University, United States
Session 2 In-vitro and In-vivo Toxicology
Session Chair Yet to be finalized
Session Co-chair Yet to be finalized
Title:A Genome-Wide Approach to the Analysis of Mutation Induction in the
Mammalian Germline
Yuri E Dubrova, University of Leicester, United Kingdom
Title:Systemic and developmental toxicity of Phthalate and ameliorative effect of
Nigella sativa on phthalate induced toxicity
Sahar Younes Ibrahim Issa, Alexandria University, Egypt
Title:Genetic and pharmaceutical toxicity - protective measures
Arumugam Ponnan, Bharathiar University, India
Title: The environmental exposures are major risk factors in development
of many human cancers.
Rajendra K Singh, Vyaire Medicals, United States
Title: Biocompatibility of metals used in orthodontic
Maria Perpétua Mota Freitas, University of Brazil, Canoas RS, Brazil
16:40-16:50 COFFEE BREAK
Session 3
Pharmaceutical Toxicology
Environmental Chemistry
Analytical Toxicology
Session Chair Yet to be finalized
Session Co-chair Yet to be finalized
Title: Preclinical toxicological evaluation of new quinolone antibacterial. Focus
on articular toxicity potential
Jorge Gonzalez Borroto, Ferrer Internacional S.A, Spain
Title: Protective effect of picroliv aganist cyclophasphamide induced cytotoxicity
in Allium cepa root meristem
Papiya Bigoniya, DSKM College of Pharmacy, India
Title: Geogenic Arsenic Contamination in Ground Water and its
Correlation with Cancer
Arun Kumar,Mahavir Cancer Institute & Research Centre, India
Title: Uji Toksisitas Filtrat Daun Jarak Pagar (Jatropha curcas .L)
Terhadap Mortalitas Keong Mas (Pomacea canaliculata)
Mulyadi Maruni , Bina Mandiri Foundation, Indonesia
Title: Drug abuse, the problem
Raafat Mandour, Mansoura University, Egypt
16:00-16:20
16:20-16:40
16:50-17:10
17:10-17:30
17:30-17:50
17:50-18:15
18:15-18-35
15:40-16:00
14:40-15:00
15:00-15:20
15:20-15:40
3. 19:00-20:00 Cocktails
Main Hall
Symposium on
Title: What are the common pesticides presenting as acute poisoning in
Bangladesh?
Mohammad Robed Amin, Dhaka Medical College, Bangladesh
11:00-11:15 COFFEE BREAK
Title: 7,12-Dimethylbenz[a]anthracene Toxicity and Cancer
Zeliha Selamoglu, Omer Halisdemir University, Turkey
Session 1 Medical and Clinical Toxicology
Food Toxicology
Session Chair Mohammad Rafiqul Islam
Session Co-chair Yet to be finalized
Title: Clinical Pattern and Epidemiological Factors of Acute Poisoning in a
Tertiary Hospital of Central Bangladesh
Mohammad Rafiqul Islam,Shaheed M Monsur Ali Medical College. Bangladesh
Title: Restoration of Hypertrophy-Induced by Norepinephrine Through
Opening of ATP sensitive Potassium Channel
Betul Ozaltun, Omer Halisdemir University, Turkey
Title: The relationship betweendoxorubicin’s liver toxicity and hepatic
renin-angiotensin system
Fatih Mehmet Gur, Omer Halisdemir University, Turkey
13:15-14:00 Lunch Break
Title: How does AMPK Inhibition atCardiotoxicity-Induced by Doxorubicin
occur?
Celal Guven, Omer Halisdemir University, Turkey
Title: Does HMGB1 gene silence really attenuatedoxorubicin’s cardiotoxicity?
Eylem Taskin, Omer Halisdemir University, Turkey
Title: Two cases of cured Foodborne Botulism. Does the addition of higher dose
Cobalamin make any difference?
Islam Aboelyazeed Aied, Soliman Fakeeh Hospital, Egypt
Title: A sugar-based gelator for eco-friendly marine oil-spill recovery
Muvvala Venkatanarayana, Gitam University, India
Title: Linking the corticoptropin-releasing factor, the heat shock preotein-27
and thioredoxin-1 in drug addiction and cellular toxicity in both, the brain and the
heart
Juan Antonio Garcia , Reina Sofia University Hospital, Spain
Title: Probiotics - boon for bioremediation of toxic Metals
Chand Ram, ICAR- National Dairy Research Institute, India
12:55-13:15
14:00-14:20
14:20-14:40
14:40-15:00
15:00-15:20
15:20-15:40
15:40-16:00
12:35-12:55
Day 2 June 12,2018
10:00-11:00
11:15-12:15
12:15-12:35
4. 16:00-16:15 COFFEE BREAK
Session 3 Metallic Toxicology
Pathology &Immunology
Regulatory Toxicology
Microbiology and Toxicology
Session Chair Yet to be finalized
Session co-Chair Yet to be finalized
Title: Investigation of mutagenesis effect of silver nanoparticles
in the Escherichia coli
Bahram Golestani Eimani , Islamic Azad university, Iran
Title: The physicochemical properties of lipids in shea butter nut
(butyrosperum parkii) and its effects on some organs of albino rats
Babatunde Oluwafemi Adetuyi, Joseph Ayo Babalola University, Nigeria
Title: Cellular stress in eukaryotic cells due to metal and metal oxide nanoparticles
Yogendrakumar Lahir, Univ of Mumbai, India
Title: Positively Negative: Proving the “absence-of-effect” hypothesis in safety
assessment
Mark Maier, Sheperian Toxicology, LLC, United States
Title: Serum Carbonic Anhydrase 1 is a Biomarker for Diagnosis of Human
Schistosoma mansoni Infection.
Manal Kardoush, Benha University, Egypt
Title: The biocontrol activity and ecological impact of surfactin AfromBacillus
subtilis against fumonisin B1 produced by Fusarium species
Ambrin Sarwar, COMSATS Institute of Information Technology, Pakistan
Title:Organochlorine pesticides and low birth weight: is there any association?
Madhu Anand, Dr. B R Ambedkar University, India
Title: Effect of arsenic exposure on histo-architecture of ovarian tissue in young
female rat
Zertashia Akram, COMSATS Institute of Information Technology,
Islamabad, Pakistan
Title: Biological Monitoring of Health Pesticide exposure among Agricultural
farm workers in Tanzania.
Raphael John Mwezi, Tropical Pesticide Research Institute, Tanzania
Title: brain response in some systemic immune condition- toxicological aspects
Mauro Luisetto, independent researcher, Italy
Title: Autopsic examination case of Levomepromazine toxicity
Satoshi Fatoshi Furukawa, Shiga University of Medical Science, Japan
Title: Opiate withdrawal syndrome in buprenorphine abusers admitted to a
rehabilitation center in Tunisia
Ghorbel, Hygiene Laboratory Hedi Chaker Hospital, Toxicology Unit,
South of Tunisia
P-005
P-006
17:55-17:15
Poster Presentations @ 17:15-18:15
P-001
P-002
P-003
P-004
17:35-17:55
16:15-16:35
16:35-16:55
16:55-17:15
17:15-17:35