Which of the following would provide the best evidence that an early form of targeted cell-cell communication was present before the evolution of complex multicellular organisms? Question 7 options: Discovery of transmembrane proteins in a variety of bacteria Plants discovered that use a combination of plasmodesmata and gap junctions Discovery of an amoeba that forms connections between its plasma membrane and the plasma membrane of other amoebae Cell adhesion molecules present in plant cells also discovered in fungi Save Discovery of transmembrane proteins in a variety of bacteria Plants discovered that use a combination of plasmodesmata and gap junctions Discovery of an amoeba that forms connections between its plasma membrane and the plasma membrane of other amoebae Cell adhesion molecules present in plant cells also discovered in fungi Solution Mechanisms enabling cell-cell communications are well documented in various eukaryotes of higher orders. These cells typically use tight junctions and gap junctions to secrete and exchanging chemicals as a form of sharing information.Mechanisms enabling one cell to influence the behavior of another almost certainly existed in the world of unicellular organisms long before multicellular organisms appeared on Earth. In order to solve the above problem, we need to look at the most simplest organism possessing traits of cell communication. The first option related to the discovery of trasnmembrane proteins in bacteria. Although bacteria are prokaryotes, the presence of transmembrane proteins have more to do with signal transduction, as compared to cell-cell communication between two independent cells. The second option can clearly be negated since it deals with plants. The third and fourth option deals with the presence of cell adhesion molecules found in amoeba and fungi. Now both these organisms are simple unicellular organisms, and the presence of cell adhesion apparatus would validate our theory, However, for all practical purposes, one can choose option 4 above 3, for the singular reason that fungii are more simple and less developed than amoeboid cells. Moreover, there is evidence to prove that fungi can communicate and influence one another\'s behavior in preparation for sexual mating. In the budding yeast Saccharomyces cerevisiae, for example, when a haploid individual is ready to mate, it secretes a peptide mating factor that signals cells of the opposite mating type to stop proliferating and prepare to mate. Therefore, the correct option is Option 4..