What roles do the weak chemical forces (ionic bonding, hydrogen bonding, van der Waals interaction and hydrophobic interaction) play in the structure of membranes? Solution Weak forces like hydrogen bonding, ionic bonding, van der Waals interaction and hydrophobic interactions imparts stability to the plasma membrane by create constantly forming and breaking interations. Pheripheral proteins interact and anchored to the plasma membrane integral protein surfaces by weak chemical bonds by their polar nature..