how can second messengers amplify a signal initiated by a toxicant or drug?
Solution
A toxicant or a drug can be considered as the first messenger.When these messengers bind to
their respective receptors,they may not always be able to pass through the phospholipid bilayer
of the plasma membrane to enter the cell and initiate the signalling process.In such cases,
secondary messengers helps to relay the signals from the recepors into the cell and in doing so,
they also amplify the signal received.This amplification of a signal is brought about by activating
many multi-cyclic kinase cascades and many intracellular signalling processes at a time.Thus for
one every receptor that is bound by a drug /toxicant, the signal is amplified many times..
how can second messengers amplify a signal initiated by a toxicant o.pdf
1. how can second messengers amplify a signal initiated by a toxicant or drug?
Solution
A toxicant or a drug can be considered as the first messenger.When these messengers bind to
their respective receptors,they may not always be able to pass through the phospholipid bilayer
of the plasma membrane to enter the cell and initiate the signalling process.In such cases,
secondary messengers helps to relay the signals from the recepors into the cell and in doing so,
they also amplify the signal received.This amplification of a signal is brought about by activating
many multi-cyclic kinase cascades and many intracellular signalling processes at a time.Thus for
one every receptor that is bound by a drug /toxicant, the signal is amplified many times.
