This study examined weight loss strategies used by overweight adults with type 2 diabetes participating in the Look AHEAD clinical trial. Less than half of participants self-weighed at least weekly. Participants ate breakfast most days but also ate several meals and snacks per day and almost two fast food meals per week on average. The most common weight control practices involved increasing fruits and vegetables or reducing sweets or high-carbohydrate foods. Self-weighing less than weekly, eating more fast food meals, and fewer breakfast meals were associated with higher BMI after controlling for other factors. Regular self-weighing and breakfast consumption along with limiting fast food were related to lower BMI.