A web application framework is software designed to support the development of dynamic web applications and services. It aims to reduce overhead in common development tasks like database access, templating, and session management. Many frameworks follow the Model-View-Controller pattern and promote code reuse through libraries and tools. The document then discusses specific frameworks like Struts 2, Spring, Flex, Silverlight, Laszlo, Ruby on Rails, Yii, Zend, CakePHP, Node.js, and Django.